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Systematic Reviews & Meta-analysis

Systematic Review | Conservative vs. surgical management for femoro-acetabular impingement.

19 Oct, 2022 | 14:09h | UTC

Conservative vs. Surgical Management for Femoro-Acetabular Impingement: A Systematic Review of Clinical Evidence – Journal of Clinical Medicine

Related:

Arthroscopic hip surgery compared with personalised hip therapy in people over 16 years old with femoroacetabular impingement syndrome: UK FASHIoN RCT – Health Technology Assessment

Arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of symptomatic femoroacetabular impingement: multicentre randomised controlled trial – The BMJ

 


Systematic Review | Reconstructive surgery for treating pressure ulcers – little evidence to guide recommendations.

18 Oct, 2022 | 12:46h | UTC

Reconstructive surgery for treating pressure ulcers – Cochrane Library

 


Interpreting and assessing confidence in network meta-analysis results: an introduction for clinicians.

18 Oct, 2022 | 12:39h | UTC

Interpreting and assessing confidence in network meta-analysis results: an introduction for clinicians – Journal of Anesthesia

 


M-A | Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome.

18 Oct, 2022 | 12:37h | UTC

Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials – Therapeutic Advances in Endocrinology and Metabolism

 


M-A | Association of atrial septal aneurysm and shunt size with stroke recurrence and benefit from patent foramen ovale closure.

17 Oct, 2022 | 12:24h | UTC

Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure – JAMA Neurology (free for a limited period)

Commentary: Anatomic Features Key for Selecting Patients Best Suited to PFO Closure – TCTMD

 

Commentary on Twitter

 


M-A | The prognostic value of CAC zero among individuals presenting with chest pain.

14 Oct, 2022 | 14:10h | UTC

The Prognostic Value of CAC Zero Among Individuals Presenting With Chest Pain: A Meta-Analysis – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)

 


M-A | Incidence of cutaneous adverse events with Phosphoinositide 3-Kinase inhibitors as adjuvant therapy in patients with cancer.

14 Oct, 2022 | 14:01h | UTC

Incidence of Cutaneous Adverse Events With Phosphoinositide 3-Kinase Inhibitors as Adjuvant Therapy in Patients With Cancer: A Systematic Review and Meta-analysis – JAMA Oncology (free for a limited period)

 


M-A | Clinical effectiveness of tenotomy versus tenodesis for long head of biceps pathology.

13 Oct, 2022 | 13:41h | UTC

Clinical effectiveness of tenotomy versus tenodesis for long head of biceps pathology: a systematic review and meta-analysis – BMJ Open

 


M-A | Complications of hidradenitis suppurativa after surgical management.

13 Oct, 2022 | 13:40h | UTC

Complications of hidradenitis suppurativa after surgical management: A systematic review and meta-analysis – International Wound Journal

Commentary: Assessing Surgical Complications in Management of Hidradenitis Suppurativa – AJMC

 


Systematic Review | Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency.

13 Oct, 2022 | 13:39h | UTC

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency – Cochrane Library

Summary: Which hormonal therapy works better for women with early failure of the ovaries? – Cochrane Library

 

Commentary on Twitter

 


Systematic Review | Splinting for the non‐operative management of developmental dysplasia of the hip in children under six months.

12 Oct, 2022 | 13:53h | UTC

Splinting for the non‐operative management of developmental dysplasia of the hip (DDH) in children under six months of age – Cochrane Library

 


M-A | Higher vs. lower oxygenation strategies in the general intensive care unit population.

11 Oct, 2022 | 13:25h | UTC

Higher versus lower oxygenation strategies in the general intensive care unit population: A systematic review, meta-analysis and meta-regression of randomized controlled trials – Journal of Critical Care

Related:

Oxygen targets – Intensive Care Medicine (if the link is paywalled, try this one)

Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’ – Respirology

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

 


Systematic Reviews | Little evidence from RCTs on crisis interventions for adults with borderline personality disorder.

6 Oct, 2022 | 13:38h | UTC

Crisis interventions for adults with borderline personality disorder – Cochrane Library

Summary: Crisis interventions for people with borderline personality disorder – Cochrane Library

 


Systematic Review | There is little evidence on pharmacological interventions to prevent weight gain in people with schizophrenia.

6 Oct, 2022 | 13:39h | UTC

Pharmacological interventions for prevention of weight gain in people with schizophrenia – Cochrane Library

Summary: How effective are medications given alongside antipsychotics at preventing weight gain in people with schizophrenia? – Cochrane Library

 


M-A | Efficacy and safety of JAK inhibitors in the treatment of psoriasis and psoriatic arthritis.

6 Oct, 2022 | 13:37h | UTC

Efficacy and safety of JAK inhibitors in the treatment of psoriasis and psoriatic arthritis: a systematic review and meta-analysis – BMC Rheumatology

 


Systematic Review | Compression following treatment of superficial venous incompetence.

4 Oct, 2022 | 14:28h | UTC

Compression following treatment of superficial venous incompetence: systematic review – British Journal of Surgery (link to abstract – $ for full-text)

 


M-A of randomized trials | Colchicine and coronary heart disease risks.

3 Oct, 2022 | 14:00h | UTC

Colchicine and coronary heart disease risks: A meta-analysis of randomized controlled clinical trials – Frontiers in Cardiovascular Medicine

Related:

M-A: Colchicine after percutaneous coronary intervention significantly reduces the risk of major adverse cardiovascular events in patients with symptomatic coronary artery disease.

Expert Analysis | Colchicine in acute coronary syndrome: when to commence?

M-A: Colchicine in patients with coronary artery disease – “colchicine reduces the risk of myocardial infarction and stroke, but has a higher rate of gastrointestinal upset with no influence on all‐cause mortality”.

Review: Colchicine and the heart.

M-A: Colchicine administration for percutaneous coronary intervention

M-A: Efficacy and safety of low-dose colchicine in patients with coronary disease

Meta-analysis: Colchicine reduces new cardiovascular events in patients with coronary artery disease

Expert analysis: Efficacy and safety of colchicine in patients with chronic stable coronary disease

#ESCCongress – [Abstract Only] Randomized trial: Colchicine in patients with chronic coronary disease

#ESCCongress – Randomized trial: Colchicine not beneficial for patients with acute coronary syndrome

#ESCCongress – Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)

#AHA19 – [Abstract Only] Practice Changing? – Randomized Trial: Low-Dose Colchicine Improves Outcomes after Myocardial Infarction

Research: Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome

 


Systematic Review | Randomized clinical trials of machine learning interventions in health care.

30 Sep, 2022 | 12:37h | UTC

Randomized Clinical Trials of Machine Learning Interventions in Health Care: A Systematic Review – JAMA Network Open

 


Systematic Review | Increased vs. stable doses of inhaled corticosteroids for exacerbations of asthma in adults and children.

30 Sep, 2022 | 12:30h | UTC

Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children – Cochrane Library

 


Systematic Review | Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.

30 Sep, 2022 | 12:29h | UTC

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome – Cochrane Library

 

Commentary on Twitter

 


Systematic Review | Laser therapy for treating hypertrophic and keloid scars – not enough evidence to guide recommendations.

30 Sep, 2022 | 12:27h | UTC

Laser therapy for treating hypertrophic and keloid scars – Cochrane Library

Summary: Laser therapy for hypertrophic and keloid scars – Cochrane Library

 


M-A | Carbon dioxide laser vs. vaginal estrogen for genitourinary syndrome of menopause.

29 Sep, 2022 | 13:24h | UTC

Comparison of Severity of Genitourinary Syndrome of Menopause Symptoms After Carbon Dioxide Laser vs Vaginal Estrogen Therapy: A Systematic Review and Meta-analysis – JAMA Network Open

Related: RCT: Laser treatment not better than sham treatment on symptom severity in women with postmenopausal vaginal symptoms.

 

Commentary on Twitter

 


M-A of randomized trials | Regional anesthesia techniques and postoperative delirium.

28 Sep, 2022 | 13:48h | UTC

Regional anesthesia techniques and postoperative delirium: systematic review and meta-analysis – Minerva Anestesiologica

Related:

Effect of regional anesthesia on the postoperative delirium: A systematic review and meta-analysis of randomized controlled trials – Frontiers in Surgery

RCT: In older patients undergoing hip fracture surgery, regional anesthesia did not reduce the incidence of postoperative delirium compared to general anesthesia.

 


M-A | Combination therapy with long-acting bronchodilators and risk of adverse cardiovascular events in patients with COPD.

28 Sep, 2022 | 13:40h | UTC

Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis – European Respiratory Journal (link to abstract – $ for full-text)

 


Systematic Reviews | Pharmacological interventions for the treatment of disordered and problem gambling.

28 Sep, 2022 | 13:39h | UTC

Pharmacological interventions for the treatment of disordered and problem gambling – Cochrane Library

 


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