Systematic Reviews & Meta-analysis
M-A of RCT | Sleep deprivation is not effective as a treatment for major depressive episodes.
26 Oct, 2022 | 14:29h | UTC
M-A | Non-affective psychotic disorders and risk of dementia.
26 Oct, 2022 | 14:30h | UTCCommentaries:
Psychotic Disorders May Raise Risk for Later Dementia – HealthDay
M-A | Non-pharmacologic and pharmacologic treatments for anxiety in long-term care.
26 Oct, 2022 | 14:26h | UTC
Systematic Review | Point-of-care ultrasound in dyspnea, nontraumatic hypotension, and shock.
25 Oct, 2022 | 13:16h | UTC
Systematic Review | Mu‐opioid antagonists for opioid‐induced bowel dysfunction in palliative care and people with cancer.
25 Oct, 2022 | 13:13h | UTC
Systematic Review | Antipsychotic polypharmacy reduction vs. polypharmacy continuation for people with schizophrenia.
25 Oct, 2022 | 13:12h | UTCSummary: Reduction in the number of antipsychotics for people with schizophrenia – Cochrane Library
Related: Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations – Drugs
M-A of RCT | Analgesic efficacy and risk of low-to-medium dose intrathecal morphine in patients undergoing cardiac surgery.
25 Oct, 2022 | 13:10h | UTC
Conservative interventions for treating urinary incontinence in women: an overview of Cochrane systematic reviews.
24 Oct, 2022 | 14:13h | UTC
Systematic Review | Systemic corticosteroids for radicular and non‐radicular low back pain.
24 Oct, 2022 | 14:03h | UTCSystemic corticosteroids for radicular and non‐radicular low back pain – Cochrane Library
Systematic Review | Topical corticosteroids for dry eye.
24 Oct, 2022 | 14:02h | UTCTopical corticosteroids for dry eye – Cochrane Library
Systematic Review | TNF inhibitors for juvenile idiopathic arthritis‐associated uveitis.
21 Oct, 2022 | 12:55h | UTC
M-A | Safety and efficacy of tyrosine kinase inhibitors for the treatment of multiple sclerosis.
21 Oct, 2022 | 12:53h | UTC
M-A | The optimal timing for non-culprit PCI in patients with multivessel coronary artery disease.
21 Oct, 2022 | 12:52h | UTC
M-A | Scalp block for postoperative pain after craniotomy.
21 Oct, 2022 | 12:51h | UTC
M-A | Efficacy and safety of ketamine vs. electroconvulsive therapy among patients with major depressive episode.
20 Oct, 2022 | 12:30h | UTCEfficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis – JAMA Psychiatry (free for a limited period)
Commentary on Twitter
While #ElectroconvulsiveTherapy may be more efficacious than #ketamine for #depression severity in the acute phase, treatment options should be individualized and patient-centered. https://t.co/4poayVgsTG
— JAMA Psychiatry (@JAMAPsych) October 19, 2022
M-A of RCT | Carvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis.
20 Oct, 2022 | 12:25h | UTCCarvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis in a competing-risk meta-analysis – Journal of Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
#Carvedilol
➡️non-selective #βblocker
✅associated with reduced risk of decompensating events
➡️improved survival in patients with #cirrhosis & #portalhypertensionRead it here?https://t.co/yy8DIJBhfL#LiverTwitter pic.twitter.com/XxmrB7gff8
— Journal of Hepatology (@JHepatology) October 13, 2022
M-A | Interventions associated with reduced loneliness and social isolation in older adults.
19 Oct, 2022 | 14:22h | UTCRelated:
Loneliness and health – Nature Reviews Disease Primers (if the link is paywalled, try this one)
The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ
Social Isolation and Loneliness – World Health Organization
Psychological Distress and Loneliness Reported by US Adults in 2018 and April 2020 – JAMA
M-A | Endothelin receptor antagonists do not improve outcomes in idiopathic pulmonary fibrosis.
19 Oct, 2022 | 14:14h | UTC
M-A | Safety of sotagliflozin in diabetes mellitus type 1 and type 2.
19 Oct, 2022 | 14:12h | UTC
M-A | Cardiovascular and renal efficacy and safety of sodium-glucose cotransporter-2 inhibitors in patients without diabetes.
19 Oct, 2022 | 14:11h | UTC
Systematic Review | Conservative vs. surgical management for femoro-acetabular impingement.
19 Oct, 2022 | 14:09h | UTCRelated:
Systematic Review | Reconstructive surgery for treating pressure ulcers – little evidence to guide recommendations.
18 Oct, 2022 | 12:46h | UTCReconstructive surgery for treating pressure ulcers – Cochrane Library
Interpreting and assessing confidence in network meta-analysis results: an introduction for clinicians.
18 Oct, 2022 | 12:39h | UTC
M-A | Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome.
18 Oct, 2022 | 12:37h | UTC
M-A | Association of atrial septal aneurysm and shunt size with stroke recurrence and benefit from patent foramen ovale closure.
17 Oct, 2022 | 12:24h | UTCAssociation of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure – JAMA Neurology (free for a limited period)
Commentary: Anatomic Features Key for Selecting Patients Best Suited to PFO Closure – TCTMD
Commentary on Twitter
Patients with both large shunt and atrial septal aneurysm (ASA) benefit substantially more from patent foramen ovale than patients with large shunt alone, small shunt and ASA, or neither large shunt or ASA. https://t.co/lYL5sOnTCW #Research
— JAMA Neurology (@JAMANeuro) October 11, 2022