Psychiatry
RCT: Methylphenidate may improve apathy in patients with Alzheimer Disease.
28 Sep, 2021 | 09:06h | UTCEffect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Editorial: Methylphenidate for Apathy in Alzheimer Disease—Why Should We Care? (free for a limited period)
Commentary on Twitter
Small to medium effects of methylphenidate for apathy in AD. Good to see a positive symptomatic treatment trial but I wonder just how important the improvements are to patients and their families. https://t.co/nGSxlAntAd
— Robert Howard (@ProfRobHoward) September 27, 2021
M-A of randomized trials: Efficacy of exercise combined with standard treatment for depression compared to standard treatment alone.
28 Sep, 2021 | 08:55h | UTC
Commentary on Twitter
Meta-analysis: Exercise combined with standard treatments for depression is more effective than standard treatments alone. https://t.co/TlePIyvzo3 pic.twitter.com/h6eRoKFLUt
— Steve Stewart-Williams (@SteveStuWill) September 18, 2021
Cohort Study: Insulin resistance linked to increased risk of major depressive disorder.
24 Sep, 2021 | 08:59h | UTCCommentaries:
Insulin Resistance Linked to Major Depressive Disorder, Dutch Study Finds – Psychiatric News Alert
Insulin resistance doubles risk of major depressive disorder – Stanford Medicine
RCT: Preemptive intervention may improve developmental outcomes in infants showing early signs of autism.
21 Sep, 2021 | 09:01h | UTCEffect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis – JAMA Pediatrics (free for a limited period)
Commentaries:
Autism therapy aimed at infants may reduce likelihood of later diagnosis – The Guardian
Commentary on Twitter
An Australian randomized clinical trial found that ‘pre-emptive’ therapy during infancy reduced #autism diagnostic behaviors and improved language ability across early childhood https://t.co/Sybbu4hRWL
— JAMA Pediatrics (@JAMAPediatrics) September 20, 2021
5000 alcohol-related cancer deaths could be prevented every year by doubling alcohol taxes in the European Region, says WHO/Europe.
21 Sep, 2021 | 08:52h | UTCRelated:
Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization
The Lancet taskforce on NCDs and economics
To improve global health, tax the things that are killing us – Financial Times
Reducing cardiovascular disease burden through targeted dietary policies
Fiscal policies for the prevention of diseases
Lamotrigine in the maintenance treatment of bipolar disorder.
19 Sep, 2021 | 23:25h | UTCLamotrigine in the maintenance treatment of bipolar disorder – Cochrane Library
Summary: Lamotrigine as a treatment for prevention of recurrence of bipolar disorder – Cochrane Library
Editorial: Brain health and its social determinants.
19 Sep, 2021 | 23:28h | UTCBrain health and its social determinants – The Lancet
Commentary on Twitter
Strong statement from @TheLancet on social determinants of mental health. The American Psychiatric Association has embraced it, as has @rcpsych https://t.co/JfRcj7KXvq
— Sir Michael Marmot (@MichaelMarmot) September 17, 2021
What an enormous global study can tell us about feeling better during the pandemic.
10 Sep, 2021 | 05:27h | UTCWhat an enormous global study can tell us about feeling better during the pandemic – Vox
Original study: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic – Nature Human Behavior
New Canadian study confirms the excess mortality associated with eating disorders.
10 Sep, 2021 | 05:03h | UTCNew Canadian study confirms the excess mortality associated with eating disorders – The Mental Elf
Original study: Excess mortality associated with eating disorders: population-based cohort study – The British Journal of Psychiatry
Commentary on Twitter
Today, @annapaspala1 summarises a new study by @KurdyakP et al, published today in @TheBJPsych, which suggests that in Ontario (Canada), mortality rates in people with eating disorders were 5-7 times higher than the general population.https://t.co/P2QmU3Qxg8 pic.twitter.com/7VrpsevF5P
— The Mental Elf (@Mental_Elf) September 1, 2021
Editorial | Anticholinergic drugs and dementia: time for transparency in the face of uncertainty.
9 Sep, 2021 | 08:57h | UTCSystematic review: Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome – Cochrane Library
Commentary on Twitter
Anticholinergic drugs may double the risk of developing dementia. What should we be doing right now?
Editorial with @JenMStevenson for @CochraneLibrary published todayhttps://t.co/808wSGPUtm— Henry Woodford (@woodford_henry) September 8, 2021
Recent cannabis use linked to increased risk of myocardial infarction in young adults: a cross-sectional study.
7 Sep, 2021 | 21:38h | UTCNews release: Recent cannabis use linked to heart attack risk in younger adults – Canadian Medical Association Journal
Commentary: Young adult cannabis consumers nearly twice as likely to suffer from a heart attack, research shows – CNN
M-A: Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia.
6 Sep, 2021 | 10:40h | UTCLong-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre–post studies – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/TheLancetPsych/status/1382314592609693703
M-A: Effect of monthly injections of naltrexone on alcohol consumption.
6 Sep, 2021 | 10:39h | UTCEffect of extended-release naltrexone on alcohol consumption: a systematic review and meta-analysis – Addiction (link to abstract – $ for full-text)
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Essentials of Diagnosis and Management.
1 Sep, 2021 | 09:04h | UTC
Many predicted some kind of ‘Covid slide’ in learning. Test results show how bad it is.
29 Aug, 2021 | 18:55h | UTCMany predicted some kind of ‘Covid slide’ in learning. Test results show how bad it is – CNN
Report: Learning during COVID-19: Reading and math achievement in the 2020-21 school year – NWEA
Related:
The Lancet Series: Active ingredients for addressing youth anxiety and depression.
27 Aug, 2021 | 09:05h | UTCHomepage: Active ingredients for addressing youth anxiety and depression – The Lancet Psychiatry (free registration required for all articles)
See commentary: The benefits and harms of antidepressants for youth depression and anxiety #ActiveIngredientsMH – The Mental Elf
Identifying and integrating active ingredients for mental health
Commentary on Twitter
https://twitter.com/TheLancetPsych/status/1428692894165225473
Exposure to antipsychotics in womb not found to increase risk of ADHD, autism in offspring.
27 Aug, 2021 | 09:03h | UTC
Revisiting treatment options for depressed patients with generalized anxiety disorder.
27 Aug, 2021 | 08:52h | UTC
Global death toll from suicide has increased by 20,000 over the past 30 years, analysis finds.
27 Aug, 2021 | 08:28h | UTC
Systematic review: The impact of COVID-19 lockdown on child and adolescent mental health.
25 Aug, 2021 | 08:58h | UTCRelated: M-A: Child and youth mental health problems have doubled during COVID-19. (several articles on the subject)
Study commentary: How risky for developing psychosis are ‘At Risk Mental States’ in youths?
24 Aug, 2021 | 08:45h | UTCHow risky for developing psychosis are ‘At Risk Mental States’ in youths? – The Mental Elf
Original study: Systematic Review and Meta-analysis: Psychosis Risk in Children and Adolescents With an At-Risk Mental State – Journal of the American Academy of Child & Adolescent Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
Wouldn't it be great if we could identify teens at risk for psychosis & then prevent it?
Trouble is we can't- lit review shows that most "at risk" teens aren't really at risk/predictive tools don't predict accurately.
And the "At Risk" label can burden teens with stigma & meds. https://t.co/1SiBH5tQRz
— Allen Frances (@AllenFrancesMD) August 23, 2021
Adult ADHD is linked to numerous physical conditions.
24 Aug, 2021 | 08:41h | UTCAdult ADHD is linked to numerous physical conditions – Karolinska Institutet
Commentaries on Twitter
Our new study in the Swedish population shows that ADHD leads to small by significant increases in the risk for many somatic disorders: https://t.co/SYTCntG9FD https://t.co/tLQ9qSxWWF
— Stephen Faraone (he/him/his) (@StephenFaraone) July 7, 2021
Important paper in @TheLancetPsych led by @EbbaDuRietz and @LarssonPsychEpi. We found that #ADHD in adults was associated with 34 out of 35 medical conditionshttps://t.co/K8xbokzZYx pic.twitter.com/Spw0ww98X0
— Samuele Cortese (@CorteseSamuele) July 6, 2021
M-A of randomized trials: Effectiveness of psychological interventions in prison to reduce recidivism.
24 Aug, 2021 | 08:42h | UTC
Commentary on Twitter
“Interventions that ensure continuity of care in community settings should be prioritised for future research.” https://t.co/FDIz1pbx7y
— ROBERTO COLOM (@ROBERTO_COLOM) August 20, 2021
M-A: Examination of dosing of antipsychotic drugs for relapse prevention in patients with stable schizophrenia.
20 Aug, 2021 | 09:04h | UTCExamination of Dosing of Antipsychotic Drugs for Relapse Prevention in Patients With Stable Schizophrenia: A Meta-analysis – JAMA Psychiatry (free for a limited period)
Commentaries on Twitter
Crucial literature review on optimal antipsychotic dosing for long term maintenance in #Schizophrenia.
Conclusion: Seek Goldilocks "just right"- definitely not high because of bad side effects, but not so low as to risk relapse.
Often easier said than done. https://t.co/RBBPBMzn9D
— Allen Frances (@AllenFrancesMD) August 20, 2021
Doses higher than 5mg/day risperidone equivalent are not more effective for relapse prevention than lower doses in #schizophrenia. But caution is required at the lower end of the dose-response curve where relapse risk disproportionally increases https://t.co/kQcnuRtzYU
— JAMA Psychiatry (@JAMAPsych) August 19, 2021
Nine in ten children with ADHD may experience symptoms into young adulthood.
19 Aug, 2021 | 08:45h | UTCNine in Ten Children With ADHD May Experience Symptoms Into Young Adulthood – Psychiatric News Alert
Original study: Variable Patterns of Remission From ADHD in the Multimodal Treatment Study of ADHD – The American Journal of Psychiatry