Psychiatry
M-A: Fatigue and cognitive impairment in Post-COVID-19 Syndrome.
11 Jan, 2022 | 01:28h | UTC
RCT: Long-term supplementation with marine Omega-3 fatty acids does not reduce the risk of depressive symptoms.
8 Jan, 2022 | 23:10h | UTCEffect of Long-term Supplementation With Marine Omega-3 Fatty Acids vs Placebo on Risk of Depression or Clinically Relevant Depressive Symptoms and on Change in Mood Scores: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
RCT: Vitamin D supplementation does not improve outcomes in people with early psychosis.
8 Jan, 2022 | 22:52h | UTC
AAP Interim guidance on supporting the emotional and behavioral health needs of children, adolescents, and families during the COVID-19 pandemic.
17 Dec, 2021 | 09:57h | UTCCommentary: AAP Issues Guidance for Children’s Emotional Needs During COVID-19 – HealthDay
Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.
14 Dec, 2021 | 08:44h | UTCNews release: Cannabis use could cause harmful drug interactions – Washington State University
Perspective: Alcohol-related harm is a public health issue, not a lifestyle choice.
14 Dec, 2021 | 08:41h | UTCAlcohol-related harm is a public health issue, not a lifestyle choice – Health Policy Watch
Related:
COVID-19 pandemic and alcohol consumption: Impacts and interconnections – Toxicology Reports
National, Regional, and Global Burdens of Disease Attributable to Alcohol Use
Study: Alcohol Use and Burden for 195 Countries and Territories
Study: The Global Burden of Disease Attributable to Alcohol and Drug Use
Study: Global Alcohol Exposure Between 1990 and 2017 and Forecasts Until 2030
Analysis: Prioritizing Action on Alcohol for Health and Development
Research: Contribution of alcohol use disorders to the burden of dementia
Review: Neuropsychiatric assessment and management of the ICU survivor.
10 Dec, 2021 | 10:01h | UTC
Outcomes associated with caustic ingestion among 1198 adults in a national prospective database in France.
9 Dec, 2021 | 10:19h | UTCOutcomes Associated With Caustic Ingestion Among Adults in a National Prospective Database in France – JAMA Surgery (free for a limited period)
Invited commentary: Caustic Ingestion—The Haves and the Have Nots (free for a limited period)
Commentary on Twitter
Study provides nation-wide data regarding in-hospital patients' outcomes after caustic ingestion. Severity of ingestion and hospital volume are associated with mortality. If feasible, low volume hospitals should transfer patients to larger centers https://t.co/VbX1jhGbjJ
— JAMA Surgery (@JAMASurgery) December 8, 2021
Benzodiazepines: Uses, dangers, and clinical considerations.
30 Nov, 2021 | 09:59h | UTCBenzodiazepines: Uses, Dangers, and Clinical Considerations – Neurology International
M-A: Psychiatric disorders in individuals born very preterm / very low-birth weight.
28 Nov, 2021 | 21:11h | UTC
Fatigue as the chief complaint: epidemiology, causes, diagnosis, and treatment.
28 Nov, 2021 | 21:05h | UTC
Systematic Review: Quantifying anticholinergic burden and sedative load in older adults with polypharmacy.
26 Nov, 2021 | 09:58h | UTC
Commentary on Twitter
Systematic review of risk scales for anticholinergic burden and sedative overload – authors developed a comprehensive table on anticholinergics & sedatives (with potency). Check Table 2 and Table S2 (supplementary) for usable info to guide decision-making!https://t.co/JYaSuOeHqv
— deprescribing.org (@deprescribing) November 25, 2021
Systematic Review: Insufficient evidence to recommend Omega‐3 fatty acids for depression in adults.
26 Nov, 2021 | 09:54h | UTCOmega‐3 fatty acids for depression in adults – Cochrane Library
Commentary on Twitter
'At present, we do not have sufficient high‐certainty evidence to determine the effects of Omega‐3 fatty acids as a treatment for depression in adults' – updated @Cochrane_CCMD systematic review https://t.co/Bg9VNMnyGx
— The Cochrane Library (@CochraneLibrary) November 25, 2021
AGA Clinical practice update on management of chronic gastrointestinal pain in disorders of gut–brain interaction.
24 Nov, 2021 | 08:42h | UTC
Optimal dose of aripiprazole for augmentation therapy of antidepressant-refractory depression: preliminary findings based on a systematic review and dose–effect meta-analysis.
24 Nov, 2021 | 08:23h | UTC
Commentary on Twitter
Low-doses of aripiprazole [2-5 mg] as augmentation treatment for depression might achieve the optimal balance between efficacy, tolerability and acceptability, per this meta-analysis (certainty of evidence low to moderate)https://t.co/aTkcQOsORp
— Awais Aftab (@awaisaftab) November 21, 2021
RCT: Among patients with bipolar disorder or depression who had survived a recent suicide-related event, Lithium as an add on therapy was not effective for the prevention of repeat suicide-related outcomes.
21 Nov, 2021 | 22:59h | UTCLithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder – JAMA Psychiatry (free for a limited period)
Author Interview: Lithium for Suicide-Related Outcome Prevention in Veterans With Major Depression or Bipolar Disorder
Commentary: Lithium Added To Current Tx Fails to Reduce Suicide-Related Events in Veterans – Physician’s Weekly
Commentary on Twitter
VA Trial findings suggest simply adding lithium to existing medication in patients with #bipolar disorder or major depressive disorder is unlikely to be effective for preventing a broad range of repeat suicide-related events. https://t.co/QOj5UhEFKh
— JAMA Psychiatry (@JAMAPsych) November 17, 2021
What is the functional/organic distinction actually doing in psychiatry and neurology?
19 Nov, 2021 | 10:29h | UTC
Commentary on Twitter
Beautiful paper puts nails in coffin of outdated/inaccurate distinction "Functional" Vs "Organic".
Confusion causes great harms:
I've seen many 100s patients mislabeled primary psych disorder whose symptoms were really caused by medical illness/med side effect/drugs.Must read: https://t.co/Fl492ADrjE
— Allen Frances (@AllenFrancesMD) November 12, 2021
Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomized controlled trials.
17 Nov, 2021 | 08:12h | UTC
Viewpoint | How to Measure Progress in Addressing Physician Well-being: Beyond Burnout.
14 Nov, 2021 | 19:40h | UTCHow to Measure Progress in Addressing Physician Well-being: Beyond Burnout – JAMA
Related:
Physician Well-being 2.0: Where Are We and Where Are We Going?
[Abstract Only] Assessment of Risk Factors for Suicide Among US Health Care Professionals
Beyond Burnout: Docs Decry ‘Moral Injury’ From Financial Pressures of Health Care
Perspective: Hospital Administration Response to Physician Stress and Burnout
Opinion: It’s Time to Talk About Physician Burnout and Moral Injury
Systematic Review: Effect of Organization-Directed Workplace Interventions on Physician Burnout
Perspective: The 3 Causes Of Physician Burnout (And Why There’s No Simple Solution)
Physician Burnout: A Global Crisis (several resources on the subject)
The COVID pandemic has harmed researcher productivity – and mental health – “Surveys show that women, parents of young children and people of color are most affected by pandemic-related disruptions and need more support”.
12 Nov, 2021 | 10:35h | UTCThe COVID pandemic has harmed researcher productivity – and mental health – Nature
M-A: Efficacy of amisulpride for depressive symptoms in individuals with mental disorders.
12 Nov, 2021 | 10:21h | UTC
Commentary on Twitter
MA: Amisulpride 50 mg/day was associated with a larger reduction of depressive symptoms vs. placebo (SMD= −0.70; −0.92 to −0.49; I2=0.0%), and was found to be comparable to SSRIs (SMD= −0.08; −0.23 to 0.06; I2=0.0%) in dysthymia https://t.co/schW6PbZQK pic.twitter.com/p7St9pE0Cr
— P𝘧OL (@psychopharmacol) November 7, 2021
RCT: Universal screening in high schools can help identify and initiate treatment for depression in adolescents.
11 Nov, 2021 | 08:35h | UTCNews release: School-based screening increases identification of, treatment for depression – Penn State
Commentaries:
Commentaries on Twitter
In a randomized clinical trial including 12,909 students at 14 Pennsylvania public high schools, adolescents randomized to receive a depression screen and identified with symptoms had 2.1 times higher odds of initiating depression treatment. https://t.co/b0l5ShCiHf pic.twitter.com/XptJDrH0Ne
— JAMA Network Open (@JAMANetworkOpen) November 8, 2021
M-A: Offspring’s risk for suicidal behavior in relation to parental death by suicide – “the experience of losing a parent to suicide is a strong and independent risk factor for suicidal behavior in offspring”.
11 Nov, 2021 | 08:39h | UTC
Commentary on Twitter
Crucial question to ask all patients:
"Has anyone in your family committed suicide?"Review of studies shows why: https://t.co/QIysuw9DoX
— Allen Frances (@AllenFrancesMD) November 10, 2021
RCT: Effects of ketamine vs. midazolam on neurocognition at 24 hours in depressed patients with suicidal ideation.
11 Nov, 2021 | 08:37h | UTCEffects of Ketamine Versus Midazolam on Neurocognition at 24 Hours in Depressed Patients With Suicidal Ideation – The Journal of Clinical Psychiatry (link to abstract – $ for full-text)
A New Dementia Test Raises More Questions Than Answers – “A 5-minute assessment on an iPad could transform how we screen for dementia—or overwhelm the health care system with worried test-takers”.
11 Nov, 2021 | 08:29h | UTCA New Dementia Test Raises More Questions Than Answers – Wired