Pharmacology/Pharmaceutical Industry
Guideline: Antiretroviral therapy in pregnant women living with HIV
16 Sep, 2017 | 18:24h | UTCAntiretroviral therapy in pregnant women living with HIV: a clinical practice guideline – The BMJ (free guideline and infographic)
Study: Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality
16 Sep, 2017 | 18:23h | UTCMenopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women’s Health Initiative Randomized Trials – JAMA (link to abstract – $ for full-text)
Commentaries: Taking Hormones for Menopause Doesn’t Raise Early Death Risk – The New York Times (free) AND Menopause hormone therapy not linked to premature death – Reuters (free) AND Menopause hormones don’t shorten lives, long follow-up says – STAT (free)
Guideline for the Management of Chronic Pain in Patients Living With HIV
16 Sep, 2017 | 18:18h | UTC
Study: LDL-Cholesterol Lowering for the Primary Prevention of Cardiovascular Disease Among Men
16 Sep, 2017 | 18:20h | UTCCommentary: Statins cut heart deaths in men by 28% finds study – NHS Choices (free)
Metformin: a review of its potential indications
16 Sep, 2017 | 18:05h | UTCMetformin: a review of its potential indications – Drug Design, Development and Therapy (free)
Review: Targeted therapy of ovarian cancer including immune check point inhibitor
16 Sep, 2017 | 18:02h | UTC
Review: Stent thrombosis and optimal duration of dual antiplatelet therapy after coronary stenting
16 Sep, 2017 | 18:01h | UTC
Meta-analysis: More Intensive vs Less Intensive Blood Pressure Lowering in Chronic Kidney Disease
15 Sep, 2017 | 19:16h | UTCAssociation Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Intensive blood pressure lowering linked to decreased mortality in patients with chronic kidney disease – 2 Minute Medicine (free) AND Intensive BP Lowering in Chronic Kidney Disease Associated with Lower Mortality – Physician’s First Watch (free) AND Is Strict BP Control a Good Bet for CKD Patients? – MedPage Today (free registration required)
Systematic Review: Corticosteroid versus NSAIDs for the Treatment of Acute Gout
15 Sep, 2017 | 19:14h | UTCSource: EvidenceAlerts
Corticosteroids and NSAIDs did not have different effects on pain scores, but there was a higher risk of indigestion, nausea and vomiting with NSAIDs.
A range of anti-epilepsy drugs are effective as first-line treatment
15 Sep, 2017 | 19:10h | UTCA range of anti-epilepsy drugs are effective as first-line treatment – NIHR Signal (free)
Original article: Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data – Cochrane Library (link to abstract – $ for full-text)
Review: Osteoporosis drug treatment: duration and management after discontinuation
15 Sep, 2017 | 19:09h | UTC
Study: Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine
14 Sep, 2017 | 20:45h | UTCFinal efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16–26 years: a randomised, double-blind trial – The Lancet (link to abstract – $ for full-text)
Commentary: Vaccine to prevent most cervical cancers shows long-term effectiveness – eCancer News (free)
Study: Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease
14 Sep, 2017 | 20:51h | UTCTiotropium in Early-Stage Chronic Obstructive Pulmonary Disease – The New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Drug may slow early lung disease damage – Reuters (free) AND Tiotropium Boosts Lung Function in Early COPD – MedPage Today (free)
Guideline: Treatment of Type 1 Diabetes
12 Sep, 2017 | 21:11h | UTC
WHO Guideline: Hormonal contraceptive eligibility for women at high risk of HIV
12 Sep, 2017 | 21:05h | UTCHormonal contraceptive eligibility for women at high risk of HIV: Guidance Statement – World Health Organization (free PDF)
News release: Can women who are at high risk of acquiring HIV, safely use hormonal contraception? (free)
Frequently asked questions: Hormonal contraceptive eligibility for women at high risk of HIV (free)
Guideline Summary: Hormonal contraceptive eligibility for women at high risk of HIV: guidance statement – National Guideline Clearinghouse (free)
Review: Adverse effects of proton-pump inhibitor use in older adults
12 Sep, 2017 | 20:58h | UTC
Review: The Nephrotoxicity of Vancomycin
12 Sep, 2017 | 20:53h | UTCThe Nephrotoxicity of Vancomycin – Clinical Pharmacology & Therapeutics (free)
Recommendations for the treatment of hepatitis B
12 Sep, 2017 | 20:51h | UTCRecommendations for the treatment of hepatitis B in 2017 – Polish Group of Experts for HBV (free)
Recommendations for the treatment of hepatitis C
12 Sep, 2017 | 20:50h | UTCRecommendations for the treatment of hepatitis C in 2017 – Polish Group of Experts for HCV (free)
FDA approves new drug for complicated UTI
11 Sep, 2017 | 14:32h | UTCFDA News Release: FDA approves new antibacterial drug (free)
FDA approves new drug for complicated urinary tract infection – CIDRAP (free) AND FDA OKs Vabomere, New Antibacterial for Complicated UTI – Medscape (free registration Required)
Free Online Course: PrEP for Providers and Patients
11 Sep, 2017 | 00:58h | UTCStarts Today! Free Online Course: PrEParing: PrEP for Providers and Patients – Johns Hopkins University and Coursera
11 Drugs You Should Seriously Consider Deprescribing
11 Sep, 2017 | 00:24h | UTC11 Drugs You Should Seriously Consider Deprescribing – Medscape Slideshow (free registration required)
Related: Canadian Deprescribing Network (CaDeN) (free) AND CaDeN Deprescribing Guidelines and Algorithms (free) AND Deprescribing guidelines for the elderly – Ontario Pharmacy Evidence Network (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Too Many Meds? America’s Love Affair With Prescription Medication – Consumer Reports (free) AND Patient often prescribed potentially futile drugs in their final months of life – Science Daily AND The Challenge of Polypharmacy: From Rhetoric to Reality – Royal Pharmaceutical Society and Royal College of General Practitioners Partnership (free PDF) Current and future perspectives on the management of polypharmacy – BMC Family Practice (free)
Medication Adherence in Hypertension: The Role of Patient–Provider Communication
11 Sep, 2017 | 00:21h | UTCEditorial: Talking With Patients Is Better Than Talking to Patients (free)
Commentaries: Hypertension Medication Adherence May Be Improved by Collaborate Communication – Cardiology Advisor (free) AND Better Provider Communication Might Improve Medication Adherence – Medscape (free registration required) AND Talk Why, Not What for Better Antihypertensive Adherence – MedPage Today (free)
“Odds of poor med adherence 6x greater when patient-provider interactions don’t address patients’ unmet social needs” (RT @CircOutcomes see Tweet)
Study: Safety and Feasibility of Antiretroviral Preexposure Prophylaxis for Adolescent Men Who Have Sex With Men
10 Sep, 2017 | 01:30h | UTCEditorial: Human Immunodeficiency Virus Preexposure Prophylaxis for Adolescent Men (free)
Commentaries: Safety, Feasibility of PrEP for Adolescent Men Who Have Sex With Men – The JAMA Network (free) AND PrEP safe and effective for young men who have sex with men – OnMedica (free) AND HIV PrEP for adolescent men found to be safe, effective – UPI (free)
Study: Antipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities
10 Sep, 2017 | 01:31h | UTCAntipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities – The Canadian Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Antipsychotics common for adults with intellectual and developmental disabilities – Centre for Addiction and Mental Health (free) AND Antipsychotics Overused in Intellectually Disabled Adults – Medscape (free registration required)
“Antipsychotics are used inappropriately particularly in vulnerable groups: Poor children; Intellectually challenged; Autistic; Nursing homes. (RT @AllenFrancesMD see Tweet)