Pharmacology/Pharmaceutical Industry
Research: Single Dose Moxidectin vs Ivermectin for Onchocerca Volvulus Infection
21 Jan, 2018 | 16:59h | UTCEditorial: A new powerful drug to combat river blindness (free)
Research: Antipsychotics and the Risk of Aspiration Pneumonia in Individuals Hospitalized for Nonpsychiatric Conditions
16 Jan, 2018 | 18:48h | UTCAntipsychotics and the Risk of Aspiration Pneumonia in Individuals Hospitalized for Nonpsychiatric Conditions – Journal of the American Geriatrics Society, via Medscape (free registration required)
Commentary: Antipsychotics May Increase Risk of Aspiration Pneumonia in Older Adults – Psychiatric News Alert (free)
Related: Antipsychotic use in elderly patients and the risk of pneumonia – Expert Opinion on Drug Safety (free) AND Antipsychotic drug exposure and risk of pneumonia: a systematic review and meta-analysis of observational studies – Pharmacoepidemiology & Drug Safety (free)
Meta-Analysis: Premature Infants and Risk of ADHD
16 Jan, 2018 | 18:27h | UTCCommentaries: Premature Infants Particularly Vulnerable to ADHD – Psychiatric Times (free) AND ADHD and Early Experience: Revisiting the Case of Low Birth Weight – Pediatrics (free)
Research: Prenatal Exposure to Acetaminophen and Children’s Language Development
16 Jan, 2018 | 18:24h | UTCPrenatal exposure to acetaminophen and children’s language development at 30 months – European Psychiatry (link to abstract – $ for full-text)
Commentaries: Is acetaminophen really safe in pregnancy? – Medical News Today (free) AND Acetaminophen Use During Pregnancy Associated With Elevated Rate of Language Delay in Girls, Mount Sinai Researchers Find – Mount Sinai Health System, via NewsWise (free)
Meta-Analysis: Acid-Suppressive Drug Use During Pregnancy and the Risk of Childhood Asthma
16 Jan, 2018 | 18:25h | UTCAcid-Suppressive Drug Use During Pregnancy and the Risk of Childhood Asthma: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)
Commentaries: Antacids During Pregnancy Tied to Asthma in Children – The New York Times (10 articles per month are free) AND Is antacid use during pregnancy tied to childhood asthma? – Reuters (free)
Review: Pharmacotherapy for Obesity
16 Jan, 2018 | 18:05h | UTCPharmacotherapy for obesity: What you need to know – Cleveland Clinic Journal of Medicine (free)
Research: Maternal Use of Folic Acid and Multivitamins and Risk of Autism in Offspring
16 Jan, 2018 | 17:34h | UTCCommentaries: Use of Folic Acid and Multivitamins During Pregnancy May Lower Autism Risk – Psychiatry News Alert (free) AND Folic Acid, Multivitamins During Pregnancy May Cut ASD Risk – MedPage Today (free registration required) AND Are Vitamin Supplements Used Before or During Pregnancy Associated with Risk of Autism Spectrum Disorder? – The JAMA Network (free)
Research: Folic Acid Supplementation During Pregnancy and Risk of Autism in Children Exposed to Antiepileptic Drugs In Utero
16 Jan, 2018 | 17:32h | UTCAssociation of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: Lack of Folic Acid Supplements During Pregnancy Linked With Increased Autism Risk in Children Exposed to Seizure Drugs In Utero – Medical Research (free) AND Folic Acid in Pregnant Women on Antiepileptic Drugs Linked to Lower Autism Risk – Medscape (free registration required) AND Folic Acid May Limit Autism Traits in Children of Epileptic Women – MedPage Today (free registration required) AND Folic acid lessens autism risk for fetal anti-epileptic exposure – MedicalXpress (free)
A Payer’s Perspective on Drug Pricing
16 Jan, 2018 | 13:53h | UTCA Payer’s Perspective on Drug Pricing – NEJM Catalyst (free)
14 Improving Patient Flow in the ED: 7 Strategies for Nurses
16 Jan, 2018 | 13:48h | UTCWTBS 14 Improving Patient Flow in the ED: 7 Strategies for Nurses – Emergency Medicine Cases (free)
Related White Paper: Achieving Hospital-wide Patient Flow: The Right Care, in the Right Place, at the Right Time – Institute for Healthcare Improvement (free registration required – PDF)
Research: Chemoprevention of Basal and Squamous Cell Carcinoma With Fluorouracil Cream
16 Jan, 2018 | 13:25h | UTCChemoprevention of Basal and Squamous Cell Carcinoma With a Single Course of Fluorouracil, 5%, Cream: A Randomized Clinical Trial – JAMA Dermatology (link to abstract – $ for full-text)
Commentaries: 5-FU Cream Reduces Surgery in High-Risk SCC Patients – Medscape (free registration required) AND In clinical trial, cream reduces squamous cell carcinoma risk – eCancer News (free)
Meta-analysis of Interventions to Reduce Adverse Drug Reactions in Older Adults
16 Jan, 2018 | 13:17h | UTCMeta-analysis of Interventions to Reduce Adverse Drug Reactions in Older Adults – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
“Interventions designed to optimize medication use reduced the risk of any and serious ADRs in older adults. Implementation of these successful interventions in healthcare systems may improve medication safety in older adults”.
Meta-Analysis: Chemical Venous Thromboembolism Prophylaxis in Neurosurgical Patients
16 Jan, 2018 | 13:13h | UTCChemical venous thromboembolism prophylaxis in neurosurgical patients: an updated systematic review and meta-analysis – Journal of Neurosurgery (link to abstract – $ for full-text)
Chemical venous thromboembolism prophylaxis seems to be effective and safe in neurosurgical patients.
Source: EvidenceAlerts
Review: SSRIs for Relapse Prevention in Major Depressive Disorder
16 Jan, 2018 | 13:07h | UTC“Review: The relapse risk during 1 year in adults with MDD was lower when SSRIs were combined with psychotherapy. Results comparing SSRIs and SNRIs were inconclusive. TCAs may be equally as effective as SSRIs” (via @psychopharmacol see Tweet)
Research: Triple Antiplatelet Therapy After Acute Cerebral Ischemia
16 Jan, 2018 | 13:00h | UTCCommentaries: Learning from TARDIS: time for more focused trials in stroke prevention – The Lancet (free) AND Triple Antiplatelets for Reducing Dependency After Ischaemic Stroke – TARDIS – American College of Cardiology, Latest in Cardiology (free)
“Among patients with recent cerebral ischaemia, intensive antiplatelet therapy did not reduce the incidence and severity of recurrent stroke or TIA, but did significantly increase the risk of major bleeding. Triple antiplatelet therapy should not be used in routine clinical practice”.
FDA: No Codein for Kids
16 Jan, 2018 | 12:53h | UTCFDA News Release: FDA acts to protect kids from serious risks of opioid ingredients contained in some prescription cough and cold products by revising labeling to limit pediatric use (free)
Commentaries: FDA strengthens warning on opioid cold medicine – CNN (free) AND FDA: Children should not take cough medicine with codeine – AAP News (free) AND FDA Updates Labeling for Opioid-Containing Medications to Limit Use in Children – Pharmacy Times (free) AND No Opioid Cough Meds in Children Under 18, FDA Says – Medscape (free registration required)
12 Must-Know EM Pharmacotherapy Articles of 2017
16 Jan, 2018 | 12:47h | UTC12 Must-Know EM Pharmacotherapy Articles of 2017 – Academic Life in Emergency Medicine (free)
Meta-Analysis: Lactobacillus reuteri to Treat Infant Colic
13 Jan, 2018 | 18:59h | UTCLactobacillus reuteri to Treat Infant Colic: A Meta-analysis – Pediatrics (free)
Invited commentary: Is It Time To Recommend Lactobacillus for Colic? Not Necessarily (free)
Research: Oral Once-Weekly Drug Delivery System for HIV Antiretroviral Therapy
12 Jan, 2018 | 16:43h | UTCCommentary: Swallowing A ‘Mini-Pillbox’ Could Change The Way HIV Drugs Are Delivered – NPR (free) AND HIV could be treated with a once-a-week pill – Medical News Today (free)
Source: Global Health NOW Newsletter
Research: Incremental Effects of Antihypertensive Drugs
12 Jan, 2018 | 16:27h | UTCIncremental effects of antihypertensive drugs: instrumental variable analysis – The BMJ (free)
Commentary: Addition of new class of antihypertensive drug effective for lowering BP – Clinical Advisor (free)
Guideline: Pharmacological Treatment of Patients With Alcohol Use Disorder
10 Jan, 2018 | 23:18h | UTCNews release: APA Releases New Practice Guideline on Treatment of Alcohol Use Disorder – American Psychiatry Association (free)
Commentary: New Alcohol Use Disorder Guideline Emphasizes Medication – Medscape (free registration required)
Research: Use of Folic Acid and Multivitamins During Pregnancy and Risk of Autism in Offspring
10 Jan, 2018 | 00:34h | UTCCommentaries: Use of Folic Acid and Multivitamins During Pregnancy May Lower Autism Risk – Psychiatry News Alert (free) AND Folic Acid, Multivitamins During Pregnancy May Cut ASD Risk – MedPage Today (free registration required) AND Are Vitamin Supplements Used Before or During Pregnancy Associated with Risk of Autism Spectrum Disorder? – The JAMA Network (free)
Prescribing Cascade in a Cardiology Practice
10 Jan, 2018 | 00:31h | UTCPrescribing Cascade in a Cardiology Practice – American College of Cardiology, Latest in Cardiology (free)
“Before starting a medication to treat a new medical condition, consider whether this condition could be a drug-related adverse event. Specifically, consider whether this could represent a prescribing cascade”.
Research: Folic Acid Supplementation During Pregnancy and Risk of Autism in Children Exposed to Antiepileptic Drugs in Utero
10 Jan, 2018 | 00:32h | UTCAssociation of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: Lack of Folic Acid Supplements During Pregnancy Linked With Increased Autism Risk in Children Exposed to Seizure Drugs In Utero – Medical Research (free) AND Folic Acid in Pregnant Women on Antiepileptic Drugs Linked to Lower Autism Risk – Medscape (free registration required) AND Folic Acid May Limit Autism Traits in Children of Epileptic Women – MedPage Today (free registration required) AND Folic acid lessens autism risk for fetal anti-epileptic exposure – MedicalXpress (free)
Research: Ibuprofen May Produce a State of Compensated Hypogonadism
10 Jan, 2018 | 00:17h | UTCCommentary: Ibuprofen may increase risk of fertility issues in men, study suggests – The Guardian (free)