Pharmacology/Pharmaceutical Industry
Computerised decision support can improve antibiotic prescribing in hospitals
30 Nov, 2017 | 18:13h | UTCComputerised decision support can improve antibiotic prescribing in hospitals – NIHR Signal (free)
Original Article: The effectiveness of computerised decision support on antibiotic use in hospitals: A systematic review – PLOS One (free)
Meta-analysis: Oral anticoagulants for prevention of stroke in atrial fibrillation
29 Nov, 2017 | 16:50h | UTCCommentary: Comparison of Oral Anticoagulants for Preventing Stroke in AF – MPR (free)
Tens of thousands dying from $30 billion fake drugs trade, WHO says
29 Nov, 2017 | 16:48h | UTCTens of thousands dying from $30 billion fake drugs trade, WHO says – Reuters Health (free)
Related: About 11 percent of drugs in poor countries are fake, U.N. says – Associated Press (free)
Guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis
28 Nov, 2017 | 19:40h | UTCCommentaries: New HIV guideline outlines cost-effective prevention strategies for high-risk people – ScienceDaily (free)
Related Free Online Course (Starts Dec 04): PrEParing: PrEP for Providers and Patients – Johns Hopkins University and Coursera
Related guidance: WHO implementation tool for pre-exposure prophylaxis of HIV infection (free) AND Summary: WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection (free)
Review: Does contrast cause kidney injury?
28 Nov, 2017 | 19:34h | UTCDoes contrast cause kidney injury? The evidence – First10EM (free)
Meta-Analysis: Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients
28 Nov, 2017 | 19:27h | UTCProlonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
“Receipt of prolonged infusion of piperacillin-tazobactam was associated with reduced mortality and improved clinical cure rates across diverse cohorts of severely ill patients”.
Research: Tolerability profile of glucocorticoids use in early rheumatoid arthritis
28 Nov, 2017 | 19:26h | UTCCommentaries: Long-Term Safety of Glucocorticoids in Patients with Early Rheumatoid Arthritis – Journal Watch (free) AND Long-term Low-dose Steroids OK in Early RA – MedPage Today (free registration required)
“Long-Term Safety of Glucocorticoids in Early Rheumatoid Arthritis. Stopping steroids completely is difficult in patients whose disease flares with tapering, but low-dose levels are relatively safe” (RT @JWatch see Tweet)
Research: Association of Hormonal Contraception With Suicide Attempts and Suicides
25 Nov, 2017 | 22:51h | UTCAssociation of Hormonal Contraception With Suicide Attempts and Suicides – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Hormonal Contraception May Increase Risk of Suicide, Study Suggests – Psychiatric News Alert (free) AND Oral Contraceptives Linked to Suicide – Medscape (free registration required)
Guideline for treatment of cancer pain
25 Nov, 2017 | 22:48h | UTC2017 SEOM clinical guideline for treatment of cancer pain – Clinical and Translational Oncology (free)
Guideline: Deprescribing antihyperglycemic agents in older persons
25 Nov, 2017 | 22:45h | UTCRelated algorithm: Antihyperglycemic deprescribing algorithm (free PDF)
See also other Deprescribing Guidelines and Algorithms (free resources)
Choosing Wisely: Six Things Pharmacists and Patients Should Question
25 Nov, 2017 | 22:46h | UTCNew Choosing Wisely Canada list: Six Things Pharmacists and Patients Should Question (RT @CPhAAPhC see Tweet)
See more on the Choosing Wisely initiative in our April 5 issue (see #6)
Guidelines Synopsis: Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults
25 Nov, 2017 | 22:39h | UTCClinical Guidelines Synopsis: Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults – JAMA (free)
Editorial: The New 2017 ACC/AHA Guidelines “Up the Pressure” on Diagnosis and Treatment of Hypertension (free)
Related Viewpoint: The 2017 Clinical Practice Guideline for High Blood Pressure (free)
See original AHA/ACC Hypertension Guidelines and related resources in our November 13th issue (see #1)
Review: Practical Considerations for the Diagnosis and Management of Asthma in Older Adults
25 Nov, 2017 | 22:33h | UTC
Guideline: Pharmacologic management of chronic neuropathic pain
25 Nov, 2017 | 22:32h | UTCRelated article: Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
2017 ACC/AHA Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults
20 Nov, 2017 | 14:19h | UTCSee also: High Blood Pressure Guidelines Hub / Executive Summary / ACC/AHA Slide Set / ACC Key Points to Remember (free resources)
World Antibiotic Awareness Week, 13-19 November 2017
20 Nov, 2017 | 14:10h | UTCWorld Antibiotic Awareness Week, 13-19 November 2017 – World Health Organization (free resources)
Review: l-Thyroxine replacement therapy in the frail elderly
14 Nov, 2017 | 20:15h | UTC
Research: Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting
11 Nov, 2017 | 19:20h | UTCEditorial: Antibiotics or NSAIDs for uncomplicated urinary tract infection? (free)
Commentary: NSAID Compared to Antibiotic for Symptomatic Treatment of UTI – MPR (free)
Meta-Analysis: Medications That Cause Dry Mouth As an Adverse Effect in Older People
11 Nov, 2017 | 19:16h | UTCCommentaries: Dry mouth symptoms can be side effect of certain medications for older adults – American Geriatrics Society, via EurekAlert (free) AND Certain medication use associated with dry mouth in older adults – Clinical Advisor (free)
European guidelines on perioperative venous thromboembolism prophylaxis
11 Nov, 2017 | 19:14h | UTCEuropean guidelines on perioperative venous thromboembolism prophylaxis (free PDF articles):
– Patients with preexisting coagulation disorders and after severe perioperative bleeding
– Cardiovascular and thoracic surgery
– Surgery in the obese patient
– Surgery during pregnancy and the immediate postpartum period
– Day surgery and fast-track surgery
– Chronic treatments with antiplatelet agents
– Aspirin
Meta-analysis: Vancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults
11 Nov, 2017 | 19:09h | UTCVancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults: A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Vancomycin plus piperacillin-tazobactam associated with higher AKI risk – ACP Hospitalist (free)
Related article: Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children – JAMA Pediatrics (link to abstract – $ for full-text)
Clinical Practice Guideline of The Korean Diabetes Association
11 Nov, 2017 | 19:08h | UTCClinical Practice Guideline of The Korean Diabetes Association (free articles):
– Antihyperglycemic Agent Therapy for Adult Patients with Type 2 Diabetes Mellitus 2017
– Insulin Therapy for Adult Patients with Type 2 Diabetes Mellitus
– Monotherapy in Patients with Type 2 Diabetes Mellitus
– Combination Therapy of Oral Hypoglycemic Agents in Patients with Type 2 Diabetes Mellitus
Research: Drivers not always told about their prescriptions’ potentially impairing effects
11 Nov, 2017 | 18:56h | UTCCommentaries: Drivers not always told about their prescriptions’ potentially impairing effects – ACP Internist (free)
Research: Effectiveness of β-Lactam Monotherapy vs Macrolide Combination Therapy for Children Hospitalized With Pneumonia
11 Nov, 2017 | 17:03h | UTCEffectiveness of β-Lactam Monotherapy vs Macrolide Combination Therapy for Children Hospitalized With Pneumonia – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Study: Azithromycin overprescribed for kids’ pneumonia – CIDRAP (free) AND Vanderbilt study shows azithromycin overprescribed for childhood pneumonia – Vanderbilt University Medical Center, via EurekAlert (free)
Research: Association of Warfarin Use With Lower Overall Cancer Incidence
11 Nov, 2017 | 16:56h | UTC“In this population-based cohort study of 1.256.725 persons, there was a significantly lower age- and sex-adjusted incidence rate ratio of cancer among warfarin users vs nonusers”.