Pharmacology/Pharmaceutical Industry
Guideline: ADA 2018 Standards of Medical Care in Diabetes
12 Dec, 2017 | 12:18h | UTCADA 2018 Standards of Medical Care in Diabetes – Diabetes Care (Free Supplement)
News Release: American Diabetes Association Releases 2018 Standards of Medical Care in Diabetes, with Notable New Recommendations for People with Cardiovascular Disease and Diabetes (free)
Summary of Revisions: Standards of Medical Care in Diabetes—2018 (free)
Commentaries: ADA 2018 Standards Address Diabetes Drugs With CV Benefit – Medscape (free registration required)
See Updated Guideline: ADA 2019 Standards of Medical Care in Diabetes (free supplement)
Meta-analysis: Efficacy and safety of stress ulcer prophylaxis in critically ill patients
12 Dec, 2017 | 12:15h | UTC“PPIs are the most effective agents in preventing CIB, but they may increase the risk of pneumonia”.
Opinion: The ‘smart pill’ for schizophrenia and bipolar disorder raises tricky ethical questions
10 Dec, 2017 | 15:48h | UTCThe ‘smart pill’ for schizophrenia and bipolar disorder raises tricky ethical questions – STAT (free)
Review: Comprehensive Analysis of the Clinical Immuno-Oncology Landscape
10 Dec, 2017 | 15:42h | UTCComprehensive analysis of the clinical immuno-oncology landscape – Annals of Oncology (free)
Commentary: The Cancer Research Institute Announces Publication of Comprehensive Immuno-Oncology Landscape Analysis in Annals of Oncology – NewsWise (free)
Research: Contemporary Hormonal Contraception and the Risk of Breast Cancer
7 Dec, 2017 | 22:08h | UTCContemporary Hormonal Contraception and the Risk of Breast Cancer – New England Journal of Medicine (free)
Commentaries: Even Low-Dose Contraceptives Slightly Increase Breast Cancer Risk – NPR (free) AND Study confirms higher breast cancer risk with hormone-based contraception – Reuters (free) AND Small risk of breast cancer seen with hormone contraceptives – Associated Press (free) All forms of hormonal contraception carry breast cancer risk, study finds – the Guardian (free) AND Birth Control Pills Still Linked to Breast Cancer, Study Finds – The New York Times (10 articles per month are free)
Two nerve drugs are not suitable for treating long-term low back pain
7 Dec, 2017 | 22:04h | UTCTwo nerve drugs are not suitable for treating long-term low back pain – NIHR Signal (free)
Original Article: Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials – PLOS One (free)
“Evidence supports NICE guidance not to use two nerve drugs (gabapentin and pregabalin) to treat long-term lower back pain”. (RT @NIHR_DC see Tweet)
Guidelines on the Management of Diabetes
5 Dec, 2017 | 18:36h | UTCSIGN Guidelines on Pharmacological management of glycaemic control in people with type 2 diabetes & Management of diabetes – Scottish Intercollegiate Guidelines Network (free guidelines and resources) (via @kamleshkhunti)
Consensus on the Management of Bleeding in Patients on Oral Anticoagulants
5 Dec, 2017 | 18:35h | UTCCommentary and Summary: Consensus for Management of Bleeding on Oral Anticoagulants – American College of Cardiology, Latest in Cardiology (free)
Systematic Review: Vitamin D supplementation during pregnancy
5 Dec, 2017 | 18:32h | UTCCommentaries: Evidence Insufficient to Recommend Prenatal Vitamin D Supplementation, Researchers Say – Physician’s First Watch (free) AND Jury Still Out on Vitamin D Supplements in Pregnancy – MedPage Today (free registration required)
Research: Risk of death associated with new benzodiazepine use among persons with Alzheimer disease
5 Dec, 2017 | 18:31h | UTCRisk of death associated with new benzodiazepine use among persons with Alzheimer disease: A matched cohort study – International Journal of Geriatric Psychiatry (link to abstract – $ for full-text) (RT @Deprescribing see Tweet)
Commentaries: Benzodiazepines linked to increased risk of death among Alzheimer’s disease patients – News Medical (free) AND Benzodiazepines Tied to a 41% Increased Mortality Risk in AD – Medscape (free registration required)
Research: Treatment eligibility and retention in clinical HIV care:
30 Nov, 2017 | 18:15h | UTCCommentary: Immediate ART treatment improves retention rates – Boston University School of Medicine (free)
Computerised decision support can improve antibiotic prescribing in hospitals
30 Nov, 2017 | 18:13h | UTCComputerised decision support can improve antibiotic prescribing in hospitals – NIHR Signal (free)
Original Article: The effectiveness of computerised decision support on antibiotic use in hospitals: A systematic review – PLOS One (free)
Meta-analysis: Oral anticoagulants for prevention of stroke in atrial fibrillation
29 Nov, 2017 | 16:50h | UTCCommentary: Comparison of Oral Anticoagulants for Preventing Stroke in AF – MPR (free)
Tens of thousands dying from $30 billion fake drugs trade, WHO says
29 Nov, 2017 | 16:48h | UTCTens of thousands dying from $30 billion fake drugs trade, WHO says – Reuters Health (free)
Related: About 11 percent of drugs in poor countries are fake, U.N. says – Associated Press (free)
Guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis
28 Nov, 2017 | 19:40h | UTCCommentaries: New HIV guideline outlines cost-effective prevention strategies for high-risk people – ScienceDaily (free)
Related Free Online Course (Starts Dec 04): PrEParing: PrEP for Providers and Patients – Johns Hopkins University and Coursera
Related guidance: WHO implementation tool for pre-exposure prophylaxis of HIV infection (free) AND Summary: WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection (free)
Review: Does contrast cause kidney injury?
28 Nov, 2017 | 19:34h | UTCDoes contrast cause kidney injury? The evidence – First10EM (free)
Meta-Analysis: Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients
28 Nov, 2017 | 19:27h | UTCProlonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
“Receipt of prolonged infusion of piperacillin-tazobactam was associated with reduced mortality and improved clinical cure rates across diverse cohorts of severely ill patients”.
Research: Tolerability profile of glucocorticoids use in early rheumatoid arthritis
28 Nov, 2017 | 19:26h | UTCCommentaries: Long-Term Safety of Glucocorticoids in Patients with Early Rheumatoid Arthritis – Journal Watch (free) AND Long-term Low-dose Steroids OK in Early RA – MedPage Today (free registration required)
“Long-Term Safety of Glucocorticoids in Early Rheumatoid Arthritis. Stopping steroids completely is difficult in patients whose disease flares with tapering, but low-dose levels are relatively safe” (RT @JWatch see Tweet)
Research: Association of Hormonal Contraception With Suicide Attempts and Suicides
25 Nov, 2017 | 22:51h | UTCAssociation of Hormonal Contraception With Suicide Attempts and Suicides – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Hormonal Contraception May Increase Risk of Suicide, Study Suggests – Psychiatric News Alert (free) AND Oral Contraceptives Linked to Suicide – Medscape (free registration required)
Guideline for treatment of cancer pain
25 Nov, 2017 | 22:48h | UTC2017 SEOM clinical guideline for treatment of cancer pain – Clinical and Translational Oncology (free)
Guideline: Deprescribing antihyperglycemic agents in older persons
25 Nov, 2017 | 22:45h | UTCRelated algorithm: Antihyperglycemic deprescribing algorithm (free PDF)
See also other Deprescribing Guidelines and Algorithms (free resources)
Choosing Wisely: Six Things Pharmacists and Patients Should Question
25 Nov, 2017 | 22:46h | UTCNew Choosing Wisely Canada list: Six Things Pharmacists and Patients Should Question (RT @CPhAAPhC see Tweet)
See more on the Choosing Wisely initiative in our April 5 issue (see #6)
Guidelines Synopsis: Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults
25 Nov, 2017 | 22:39h | UTCClinical Guidelines Synopsis: Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults – JAMA (free)
Editorial: The New 2017 ACC/AHA Guidelines “Up the Pressure” on Diagnosis and Treatment of Hypertension (free)
Related Viewpoint: The 2017 Clinical Practice Guideline for High Blood Pressure (free)
See original AHA/ACC Hypertension Guidelines and related resources in our November 13th issue (see #1)
Review: Practical Considerations for the Diagnosis and Management of Asthma in Older Adults
25 Nov, 2017 | 22:33h | UTC
Guideline: Pharmacologic management of chronic neuropathic pain
25 Nov, 2017 | 22:32h | UTCRelated article: Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)