Pharmacology/Pharmaceutical Industry
Coronavirus drug and treatment tracker
17 Jul, 2020 | 08:46h | UTCCoronavirus Drug and Treatment Tracker – The New York Times
RIP Hydroxychloroquine? 2 studies show no benefit in early/mild COVID-19
17 Jul, 2020 | 08:59h | UTCCommentaries: New Covid-19 study, despite flaws, adds to case against hydroxychloroquine – STAT AND Hydroxychloroquine also doesn’t help Covid-19 patients who aren’t hospitalized, new study finds – CNN
Open letter: challenge trials for COVID-19
17 Jul, 2020 | 08:48h | UTCChallenge Trials for COVID-19 – 1 Day Sooner
Commentary: Scientists call for volunteers to be infected with the coronavirus to test vaccines – CNBC
ASCO Guideline update: Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers
17 Jul, 2020 | 08:28h | UTC
Review: Perioperative management of oral glucose-lowering drugs in the patient with Type 2 Diabetes
17 Jul, 2020 | 08:24h | UTC
WHO and UNICEF warn of a decline in vaccinations during COVID-19
16 Jul, 2020 | 08:36h | UTCWHO and UNICEF warn of a decline in vaccinations during COVID-19 – World Health Organization
Commentary: Officials warn about drop in childhood vaccination due to COVID-19 – CIDRAP
[Preprint] RECOVERY trial: effect of hydroxychloroquine in hospitalized patients with COVID-19
16 Jul, 2020 | 08:39h | UTC
Related Commentary on Twitter (Thread – Click for more)
HYDROXYCHLOROQUINE – Recovery trial results finally out – and hopefully puts nail in coffin. Out of 4700 people randomized… HCQ did NOT lower #covid19 mortality. It anything it was trending in wrong direction. Thread 🧵 https://t.co/6Iu0NEejON pic.twitter.com/6l85Nmz4id
— Eric Feigl-Ding (@DrEricDing) July 15, 2020
Covid-19: experts criticize claim that remdesivir cuts death rates
16 Jul, 2020 | 08:31h | UTCCovid-19: Experts criticise claim that remdesivir cuts death rates – The BMJ
Related Commentary on Twitter
Experts have criticised pharmaceutical firm Gilead Sciences after it released data suggesting that its antiviral drug remdesivir can reduce death rates for patients with covid-19. They say the research is intrinsically flawed @MartinLandray https://t.co/a1q2FxMa7C
— The BMJ (@bmj_latest) July 14, 2020
ATS Guideline: Initiating pharmacologic treatment in tobacco-dependent adults
16 Jul, 2020 | 08:20h | UTCCommentary: ATS releases new practice guideline on treating tobacco dependence in adult smokers – News Medical
[Abstract Only] Randomized trial: ticagrelor and aspirin vs. aspirin alone in acute ischemic stroke or TIA
16 Jul, 2020 | 08:17h | UTCCommentaries: Acute Stroke or Transient Ischaemic Attack Treated With Ticagrelor and ASA for Prevention of Stroke and Death – THALES – American College of Cardiology AND Ticagrelor and aspirin taken post stroke may decrease the risk of recurrent stroke – 2 Minute Medicine
[Abstract Only] Trial of Roflumilast cream for chronic plaque psoriasis
16 Jul, 2020 | 08:15h | UTCTrial of Roflumilast Cream for Chronic Plaque Psoriasis – New England Journal of Medicine
Commentary: Researchers discover that topical treatment improves chronic plaque psoriasis – Mount Sinai Hospital
An mRNA vaccine against SARS-CoV-2 — preliminary report
15 Jul, 2020 | 08:25h | UTCAn mRNA Vaccine against SARS-CoV-2 — Preliminary Report – New England Journal of Medicine
Editorial: The Covid-19 Vaccine-Development Multiverse – New England Journal of Medicine
Commentaries: Experimental COVID-19 vaccine safe, generates immune response – NIH News Release AND First data for Moderna Covid-19 vaccine show it spurs an immune response – STAT
Are you the victim of a prescribing cascade?
15 Jul, 2020 | 08:17h | UTCAre you the victim of a prescribing cascade? – Canadian Deprescribing Network
[Abstract Only] Study: Hydroxychloroquine to prevent recurrent congenital heart block in fetuses of anti-SSA/Ro-positive mothers
15 Jul, 2020 | 08:06h | UTCCommentary: Hydroxychloroquine Reduces Incidence of Heartbeat Condition in Newborns – Technology Networks
ACC Consensus on management of anticoagulant-related bleeding
15 Jul, 2020 | 08:12h | UTCKey Points: ACC Consensus on Management of Anticoagulant-Related Bleeding
Antiemetics: ASCO Guideline update
15 Jul, 2020 | 08:04h | UTCAntiemetics: ASCO Guideline Update – Journal of Clinical Oncology
Guideline executive summary: therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections
14 Jul, 2020 | 08:11h | UTC
Editorial – Ivermectin and COVID-19: Keeping Rigor in Times of Urgency
13 Jul, 2020 | 00:18h | UTCRelated Editorial: COVID-19 and the rush for self-medication and self-dosing with ivermectin: A word of caution – One Health
Determinants of COVID-19 Disease Severity in Patients with Cancer
13 Jul, 2020 | 00:06h | UTCDeterminants of COVID-19 disease severity in patients with cancer – Nature Medicine
Commentaries: New York City data suggest link between immunotherapy, poor COVID-19 outcomes – Medwire News AND Should You Delay Cancer Treatment Because of COVID-19? Study Says Most Treatments Don’t Worsen Coronavirus Infection – Memorial Sloan Kettering
Related Commentary on Twitter
Publication of MSKCC COVID-19 experience shows that receiving ICIs seems to be associated with both increased risk of hospitalization with COVID-19 (HR 2.84; P = 0.013) and severe respiratory illness (HR 2.74; P = 0.004) https://t.co/GEU4GMVT8e
— NatureRevClinOncol (@NatRevClinOncol) July 2, 2020
Observational Analysis: BCG Vaccine and COVID-19
13 Jul, 2020 | 00:02h | UTCCommentaries: Expert reaction to study looking at BCG vaccination programmes and COVID-19 deaths in different countries – Science Media Centre AND Preliminary study suggests tuberculosis vaccine may be limiting COVID-19 deaths – Virginia Tech
Podcast: Acute Kidney Injury Caused by Proton Pump Inhibitors
12 Jul, 2020 | 23:55h | UTCAcute Kidney Injury Caused by Proton Pump Inhibitors – JAMA
[Abstract Only] Randomized Trial: Intravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria
12 Jul, 2020 | 23:57h | UTCIntravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria: A Phase III Randomized Controlled Noninferiority Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
[Abstract Only] Randomized Trial: Ruxolitinib Cream for Treatment of Vitiligo
12 Jul, 2020 | 23:58h | UTCRuxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial – The Lancet
Related Commentary on Twitter
NEW—Treatment with ruxolitinib cream was associated with substantial repigmentation of vitiligo lesions up to 52 weeks of treatment, and all doses were well tolerated: finding from a randomised, controlled, phase 2 trial https://t.co/Td5nlsMcYI pic.twitter.com/CHvtspGstQ
— The Lancet (@TheLancet) July 10, 2020
Observational Study Suggests an Increased Risk of COVID-19 Among Users of Proton Pump Inhibitors
10 Jul, 2020 | 09:19h | UTCCommentaries: Increased Risk of COVID-19 Among Users of Proton Pump Inhibitors (PPIs) – American College of Gastroenterology AND Popular Heartburn Drugs Linked to Heightened COVID-19 Risk – TIME
[Abstract Only] Randomized Trial: Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts
9 Jul, 2020 | 09:22h | UTCCommentary: Baloxavir Helps Prevent Flu in Exposed Household Contacts – NEJM Journal Watch