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Pharmacology/Pharmaceutical Industry

[Abstract Only] Case-control study: Maternal use of specific antidepressant medications during early pregnancy and the risk of selected birth defects

10 Aug, 2020 | 01:51h | UTC

Maternal Use of Specific Antidepressant Medications During Early Pregnancy and the Risk of Selected Birth Defects – JAMA Psychiatry

 


AAP Clinical Report: Long-acting reversible contraception: specific issues for adolescents

7 Aug, 2020 | 03:10h | UTC

Long-Acting Reversible Contraception: Specific Issues for Adolescents – Pediatrics

Commentary: Teens need easy access to condoms and long-acting reversible contraception, say pediatricians – CNN

 


[Abstract Only] Randomized trial: Continuing vs. tapering glucocorticoids after achievement of low disease activity or remission in rheumatoid arthritis

6 Aug, 2020 | 02:53h | UTC

Continuing versus tapering glucocorticoids after achievement of low disease activity or remission in rheumatoid arthritis (SEMIRA): a double-blind, multicentre, randomised controlled trial – The Lancet

Commentary: Reducing corticosteroid use in rheumatoid arthritis – Charité – Universitätsmedizin Berlin

 

Commentary on Twitter

 


Review: Heart failure with reduced ejection fraction

6 Aug, 2020 | 02:51h | UTC

Heart Failure With Reduced Ejection Fraction: A Review – JAMA (free for a limited period)

Podcast: Update on Congestive Heart Failure – JAMA

 


AHA Scientific statement: Medical marijuana, recreational cannabis, and cardiovascular health

6 Aug, 2020 | 02:40h | UTC

Medical Marijuana, Recreational Cannabis, and Cardiovascular Health: A Scientific Statement From the American Heart Association – Circulation

News Release: Cannabis use shows substantial risks, no benefits for cardiovascular health; more research is critical – American Heart Association

Commentaries: Weed is not good for your heart, studies say – CNN AND Heart risks of marijuana use need more research – American Heart Association

 


[Abstract Only] Randomized trial: Ofatumumab vs. Teriflunomide in multiple sclerosis

6 Aug, 2020 | 02:43h | UTC

Ofatumumab versus Teriflunomide in Multiple Sclerosis – New England Journal of Medicine

 


ACA 2020 Expert consensus: Novel therapies for cardiovascular risk reduction in patients with type 2 diabetes

6 Aug, 2020 | 02:39h | UTC

2020 Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes – Journal of the American College of Cardiology

Commentary: Cardiology Group Recommends Diabetes Drugs for CV Prevention – NEJM Journal Watch

 


Coronavirus vaccine tracker: How close are we to a vaccine?

5 Aug, 2020 | 10:00h | UTC

Coronavirus vaccine tracker: how close are we to a vaccine? – The Guardian

Related: Coronavirus Vaccine Tracker – The New York Times

 


[Preprint] REGN-COV2 antibody cocktail prevents and treats SARS-CoV-2 infection in rhesus macaques and hamsters

5 Aug, 2020 | 09:56h | UTC

REGN-COV2 antibody cocktail prevents and treats SARS-CoV-2 infection in rhesus macaques and hamsters – bioRxiv

Commentaries: Regeneron’s Monoclonal Antibody Cocktail in Primates – Science Translational Medicine AND Regeneron antibody cocktail shows promise as potential COVID-19 treatment – News Medical

 


Randomized trial: Vitamin D supplementation does not reduce the risk of depression

5 Aug, 2020 | 09:47h | UTC

Effect of Long-term Vitamin D3 Supplementation vs Placebo on Risk of Depression or Clinically Relevant Depressive Symptoms and on Change in Mood Scores: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: Vitamin D doesn’t prevent depression in older adults, large study finds – CNN AND Large study confirms vitamin D does not reduce risk of depression in adults – Massachusetts General Hospital

 


[Abstract Only] Case report: Rosuvastatin myotoxicity after starting canagliflozin treatment

4 Aug, 2020 | 02:46h | UTC

Rosuvastatin Myotoxicity After Starting Canagliflozin Treatment: A Case Report – Annals of Internal Medicine

Commentary: Rosuvastatin Toxicity Observed After Use of Canagliflozin – NEJM Journal Watch

 


Drug treatments for Covid-19: Living systematic review and network meta-analysis

3 Aug, 2020 | 01:10h | UTC

Drug treatments for covid-19: living systematic review and network meta-analysis – The BMJ

 


Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: Cohort study including 8.3 million people

3 Aug, 2020 | 00:38h | UTC

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people – Heart

 


[Abstract Only] A Systematic review of the effect of delayed appropriate antibiotic treatment on the outcomes of patients with severe bacterial infections

3 Aug, 2020 | 00:20h | UTC

A Systematic Review of the Effect of Delayed Appropriate Antibiotic Treatment on the Outcomes of Patients With Severe Bacterial Infections – CHEST (link to abstract – $ for full-text)

Commentary: Does Delayed Antibiotic for Severe Infection Impact Mortality? – Journal Feed

 


[Abstract Only] Cohort Study: Cardiovascular and bleeding risks associated with nonsteroidal anti-inflammatory drugs after myocardial infarction

3 Aug, 2020 | 00:17h | UTC

Cardiovascular and Bleeding Risks Associated With Nonsteroidal Anti-Inflammatory Drugs After Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: NSAIDs Boost CV, Bleeding Risks in Post-MI Patients – TCTMD AND Concomitant NSAID Treatment After MI – American College of Cardiology AND NSAIDs increase cardiovascular, bleeding risk in Korean heart attack patients – American College of Cardiology

 


Remdesivir for severe Covid-19: A clinical practice guideline

31 Jul, 2020 | 09:01h | UTC

Remdesivir for severe covid-19: a clinical practice guideline – The BMJ

 


Single-shot Ad26 vaccine protects against SARS-CoV-2 in monkeys

31 Jul, 2020 | 08:49h | UTC

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques – Nature

Commentaries: Vaccine Candidate Delivers Protection In A Single Shot (In Monkeys) – NPR AND Novel vaccine candidate robustly protects non-human primates against SARS-CoV-2 – News Medical

 


‘A huge experiment’: How the world made so much progress on a Covid-19 vaccine so fast

31 Jul, 2020 | 08:40h | UTC

‘A huge experiment’: How the world made so much progress on a Covid-19 vaccine so fast – STAT

 


Things you should think about when you hear “vaccine by end of the year”

31 Jul, 2020 | 08:41h | UTC

Things you should think about when you hear “vaccine by end of the year” – Health News Review

 


Some scientists are taking a DIY coronavirus vaccine, and nobody knows if it’s legal or if it works

31 Jul, 2020 | 08:36h | UTC

Some scientists are taking a DIY coronavirus vaccine, and nobody knows if it’s legal or if it works – MIT Technology Review

 


[Press release] Tocilizumab did not improve outcomes in hospitalized patients with severe COVID-19 associated pneumonia

30 Jul, 2020 | 10:52h | UTC

Roche provides an update on the phase III COVACTA trial of Actemra/RoActemra in hospitalised patients with severe COVID-19 associated pneumonia

 


‘Vaccine nationalism’ threatens global plan to distribute Covid-19 shots fairly

30 Jul, 2020 | 10:21h | UTC

‘Vaccine nationalism’ threatens global plan to distribute COVID-19 shots fairly – Science

 


Randomized trial: Respiratory syncytial virus vaccination during pregnancy and effects in infants

30 Jul, 2020 | 10:15h | UTC

Respiratory Syncytial Virus Vaccination during Pregnancy and Effects in Infants – New England Journal of Medicine

 


Randomized trial: Single-dose nirsevimab for prevention of RSV in preterm infants

30 Jul, 2020 | 10:14h | UTC

Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants – New England Journal of Medicine

 


Evaluation of the mRNA-1273 vaccine against SARS-CoV-2 in monkeys

29 Jul, 2020 | 09:53h | UTC

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates – New England Journal of Medicine

Commentary: Experimental COVID-19 vaccine protects upper and lower airways in nonhuman primates – National Institutes of Health

 


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