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Pediatrics – Pulmonology

AARC Guideline: Management of pediatric patients with oxygen in the acute care setting.

8 Aug, 2021 | 23:43h | UTC

AARC Clinical Practice Guideline: Management of Pediatric Patients With Oxygen in the Acute Care Setting – Respiratory Care – American Association for Respiratory Care

 

Pediatric asthma: The REGAP consensus.

8 Aug, 2021 | 23:45h | UTC

Pediatric asthma: The REGAP consensus – Anales de Pediatría

 

Review of COVID-19: Abdominal manifestations in adults and multisystem inflammatory syndrome in children.

6 Aug, 2021 | 10:05h | UTC

Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children – Clinical Imaging

 

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

4 Aug, 2021 | 10:06h | UTC

Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2 – The Lancet Child & Adolescent Health

Invited commentary: Citizen science and biomedical research (free registration required)

Commentaries:

Expert reaction to study looking at long-lasting symptoms from COVID-19 in children – Science Media Centre

Long Covid uncommon in children, analysis finds – King’s College London

Study finds long-term Covid symptoms rare in school-age children – The Guardian

Most children with Covid-19 recover within a week, but a small percentage have long-term symptoms, a study says. – The New York Times

Related:

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Cohort study: Risk factors for long covid in previously hospitalized children.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

 

Commentary on Twitter

 

AAP Guidance: Post-COVID-19 conditions in children and adolescents.

4 Aug, 2021 | 10:01h | UTC

Post-COVID-19 Conditions in Children and Adolescents – American Academy of Pediatrics

 

RCT: Effect of a sedation and ventilator liberation protocol vs. usual care on duration of invasive mechanical ventilation in pediatric intensive care units.

4 Aug, 2021 | 08:59h | UTC

Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial – JAMA (free for a limited period)

 

Commentary on Twitter

 

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

3 Aug, 2021 | 09:05h | UTC

Six Month Follow-up of Patients With Multisystem Inflammatory Syndrome in Children – Pediatrics (PDF)

 

Cohort study: Risk factors for long covid in previously hospitalized children.

3 Aug, 2021 | 09:06h | UTC

Risk factors for long covid in previously hospitalised children using the ISARIC Global follow-up protocol: A prospective cohort study – European Respiratory Review

Commentaries:

Study investigates long-term sequelae of COVID-19 in hospitalized children – News Medical

 

Commentary on Twitter

 

[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.

12 Jul, 2021 | 03:12h | UTC

Original study (preprint): Deaths in Children and Young People in England following SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data – National Child Mortality Database / Public Health England

Commentaries: Risks of severe illness in children from COVID-19 shown to be very low in largest study yet – University of Liverpool AND Covid: Children’s extremely low risk confirmed by study – BBC

Related study from the same group (preprint): Risk factors for intensive care admission and death amongst children and young people admitted to hospital with COVID-19 and PIMS-TS in England during the first pandemic year – medRxiv

 

Review: Advances in the diagnosis and treatment of primary ciliary dyskinesia.

21 Jun, 2021 | 08:27h | UTC

Advances in the Diagnosis and Treatment of Primary Ciliary Dyskinesia: A Review – JAMA Otolaryngology – Head & Neck Surgery (free for a limited period)

 

Audio Interview: potential treatments for children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19.

18 Jun, 2021 | 08:33h | UTC

Audio Interview: Covid-19 in Children – New England Journal of Medicine

 

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

18 Jun, 2021 | 08:35h | UTC

Multisystem Inflammatory Syndrome in Children — Initial Therapy and Outcomes – New England Journal of Medicine

Editorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics

 

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

18 Jun, 2021 | 08:36h | UTC

Treatment of Multisystem Inflammatory Syndrome in Children – New England Journal of Medicine

Editorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics

Commentaries: Steroids may be effective treatment for COVID-19 complications in children – Imperial College London AND Expert reaction to study looking at treatments for COVID-19 complications in children – Science Media Centre

 

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

14 Jun, 2021 | 08:48h | UTC

Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2 – JAMA Network Open

Commentary: MIS-C Incidence 316 Persons Per 1 Million SARS-CoV-2 Infections – HealthDay

 

Commentary on Twitter

 

In youth, COVID-19 causes more complications than flu; fatality is rare.

9 Jun, 2021 | 08:23h | UTC

In youth, COVID-19 causes more complications than flu; fatality is rare – Columbia University Irving Medical Center

Original study: 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics

 

Underlying medical conditions associated with severe COVID-19 illness among children – the strongest risk factors for hospitalization were chronic and complex chronic diseases, type 1 diabetes, and obesity.

8 Jun, 2021 | 09:37h | UTC

Underlying Medical Conditions Associated With Severe COVID-19 Illness Among Children – JAMA Network Open

Commentaries: Underlying illness, respiratory infection raise risk for severe COVID in kids – CIDRAP AND COVID-19 in Children—Not Just Little Adults – JAMA Network Open

 

Commentary on Twitter

 

Synopsis | Updates to the Pediatrics Asthma Management Guidelines.

8 Jun, 2021 | 09:22h | UTC

Updates to the Pediatrics Asthma Management Guidelines – JAMA Pediatrics (free for a limited period)

Original Guideline: 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group

 

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

3 Jun, 2021 | 11:06h | UTC

6-month multidisciplinary follow-up and outcomes of patients with paediatric inflammatory multisystem syndrome (PIMS-TS) at a UK tertiary paediatric hospital: a retrospective cohort study – The Lancet Child & Adolescent Health

Commentary: Most severe effects of MIS-C in children typically resolve within six months, new research suggests – CNN AND Children who developed a rare inflammation disease after COVID-19 are mostly better after 6 months, but some still suffer fatigue and anxiety, a small UK study found – Insider AND Most severe effects of PIMS-TS resolved at six months – HealthDay

 

Commentary on Twitter

 

RCT: Among children with protracted bacterial bronchitis, a 4-week course of amoxicillin–clavulanate is not better than a 2-week course in achieving clinical cure by 28 days.

31 May, 2021 | 08:02h | UTC

Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial – The Lancet Respiratory Medicine

Commentary: Four weeks of antibiotics for kids’ chronic cough no better than 2, study finds – CIDRAP

 

Commentary on Twitter

 

ERS clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years.

20 May, 2021 | 08:21h | UTC

European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years – European Respiratory Journal

 

Cohort study of 12,306 pediatric COVID-19 patients finds only 16.5% presented with typical respiratory symptoms (cough, dyspnea). 13.9% had GI symptoms, 8.1% had dermatological symptoms (rash), 4.8% had neurological (headache), and 18.8% had other non-specific symptoms (fever, malaise, myalgia, arthralgia and disturbances of smell or taste).

14 May, 2021 | 08:48h | UTC

A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United States – Scientific Reports

Commentary: COVID-19: Majority of infected children may not show typical symptoms – Nature Publishing Group

 

Commentary on Twitter

 

Systematic review: Combination fixed‐dose beta-agonist and steroid inhaler as required is clinically effective in adults and adolescents with mild asthma.

14 May, 2021 | 08:23h | UTC

Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma – Cochrane Library

Summary: Combination fixed-dose beta agonist and steroid inhaler as required for adults or children with mild asthma – Cochrane Library

 

RCT: Tezepelumab can reduce exacerbations in adults and adolescents with severe, uncontrolled asthma.

14 May, 2021 | 08:25h | UTC

Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma – New England Journal of Medicine

Commentary: New drug shows promise against tough-to-manage asthma – MedicalXpress

 

Pfizer COVID-19 shot expanded to US children as young as 12.

12 May, 2021 | 08:53h | UTC

Pfizer COVID-19 shot expanded to US children as young as 12 – Associated Press

Counterpoint: Covid vaccines for children should not get emergency use authorization – The BMJ Opinion

Commentaries: Covid-19: FDA authorises Pfizer vaccine for children 12-15 – The BMJ AND Expert reaction to U.S. FDA authorising Pfizer-BioNTech COVID-19 vaccine for emergency use in adolescents – Science Media Centre

 

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

22 Apr, 2021 | 08:40h | UTC

Post-acute COVID-19 outcomes in children with mild and asymptomatic disease – The Lancet Child & Adolescent Health

 

Commentaries on Twitter

 

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