Pediatrics – Critical Care & Emergencies
Case-control study | Risk variants in the exomes of children with critical illness.
10 Nov, 2022 | 13:52h | UTCRisk Variants in the Exomes of Children With Critical Illness – JAMA Network Open
Guideline | Intravenous maintenance fluid therapy in acute and critically ill children.
9 Nov, 2022 | 12:32h | UTC
Commentary on Twitter
The @ESPNIC_Society guidelines for IV maintenance fluid therapy in acute & critically ill children, SR/MA:
➡️indications for use
?isotonic fluids
?balanced solutions
?composition: Ca, Mg, K, glucose, micronutrients
?optimal amount#PedsICU #FOAMcc
?️https://t.co/ZZwHX1IaUh pic.twitter.com/KGr4e2dFg4— Intensive Care Medicine (@yourICM) October 26, 2022
RCT | Early amino acids in extremely preterm infants did improve neurodisability at 2 Years.
7 Nov, 2022 | 12:52h | UTCEarly Amino Acids in Extremely Preterm Infants and Neurodisability at 2 Years – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Extra Parenteral Amino Acids No Benefit for Extremely Preterm Infants – HealthDay
Commentary on Twitter
ProVIDE trial @NEJM: In ELBW infants, extra parenteral amino acids at a dose of 1 g/day for 5 days after birth did not improve survival free from neurodisability at 2 yrs.
Higher rates of mod-sev disability noted in intervention group.https://t.co/8hT3Ol3qOi#EBNEOalerts #neoEBM pic.twitter.com/2Z9qgkQF54— Evidence-Based Neo (@EBNEO) November 5, 2022
AAP Policy Statement | Optimizing pediatric patient safety in the emergency care setting.
3 Nov, 2022 | 14:04h | UTCOptimizing Pediatric Patient Safety in the Emergency Care Setting – Pediatrics
Technical Report: Optimizing Pediatric Patient Safety in the Emergency Care Setting – Pediatrics
Commentary: AAP Addresses Safety for Children in Emergency Care Settings – HealthDay
Caffeine to prevent intermittent hypoxemia in late preterm infants: randomized controlled dosage trial.
21 Oct, 2022 | 12:49h | UTCSummary: What dose of caffeine to use? – Neonatal Research
Commentary on Twitter
Caffiene for late prems and reduction of intermittent hypoxaemia events by Oliphant et al in @ADC_FN #EBNEOalerts #neoEBM #neotwitter https://t.co/bkKqRabe0h pic.twitter.com/VRV8GHrywN
— Evidence-Based Neo (@EBNEO) September 2, 2022
Cohort Study | New and progressive medical conditions after pediatric sepsis hospitalization requiring critical care.
13 Oct, 2022 | 13:45h | UTCNew and Progressive Medical Conditions After Pediatric Sepsis Hospitalization Requiring Critical Care – JAMA Pediatrics (free for a limited period)
Commentary on Twitter
The development or progression of comorbid conditions occurred in over 10% of children who survived #sepsis hospitalization, suggesting that they may benefit from structured follow-up to identify and address new or worsening medical conditions. https://t.co/yfAt60PsU6
— JAMA Pediatrics (@JAMAPediatrics) October 11, 2022
AAP Clinical Report | Evaluation for bleeding disorders in suspected child abuse.
3 Oct, 2022 | 14:03h | UTCEvaluation for Bleeding Disorders in Suspected Child Abuse – Pediatrics’
Technical Report: Evaluating for Suspected Child Abuse: Conditions That Predispose to Bleeding – American Academy of Pediatrics
Commentary: AAP guidance helps distinguish bleeding disorders from abuse – MDedge
Systematic Review | Home care for bronchiolitis.
21 Sep, 2022 | 13:14h | UTCHome Care for Bronchiolitis: a Systematic Review – Pediatrics
Commentary on Twitter
Given the growing interest in and potential impact of the Hospital-at-Home model, this review helps determine whether bronchiolitis requiring hospital-level care is feasible, acceptable to families, and can be safely managed in the home: https://t.co/eISjhYmRdd #Pediatrics pic.twitter.com/qjJYSDUTOq
— AAP Pediatrics (@aap_peds) September 6, 2022
Review | Aerosol delivery of lung surfactant and nasal CPAP in the treatment of neonatal respiratory distress syndrome.
19 Sep, 2022 | 12:29h | UTC
RCT | Among neonates with probable bacterial infection, switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) was noninferior to a full course of intravenous antibiotics and resulted in shorter hospitalization (median duration of 3.4 vs. 6.8 days).
16 Sep, 2022 | 12:59h | UTCEfficacy and safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentary: Dutch team devise less painful ‘drip and drink’ antibiotics treatment for babies – Dutch News
Commentaries on Twitter
*New trial*—early switch to #OralAntibiotics is not inferior to full-course IV antibiotics in #neonates with probable bacterial infection; & adverse events were not increased with use of oral antibiotics
By @IKMReiss @karelallegaert & colleagues
https://t.co/2yzeh3ptuc pic.twitter.com/BgBosxfECC
— The Lancet Child & Adolescent Health (@LancetChildAdol) September 12, 2022
In term and near-term infants <28 days with probable bacterial infection, how safe is it to switch to oral Amox-Clav as opposed to completing a course of intravenous antibiotics? A new RCT in @Lancet tries to answer this question.https://t.co/M2Za54cfxF#EBNeoAlerts#NeoEBM pic.twitter.com/zKpIiW1Whx
— Evidence-Based Neo (@EBNEO) September 12, 2022
(Thread – click for more)
Efficacy & safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) vs full course of IV antibiotics in neonates with probable bacterial infection (RAIN):multicentre, randomised,open-label,non-inferiority trial -The Lancet https://t.co/mcyr9bILRq
— Prof. Dr. Sanjeev Bagai (@BagaiDr) September 13, 2022
Review | Multisystem inflammatory syndrome in children (MIS-C) and neonates (MIS-N) associated with COVID-19: optimizing definition and management.
14 Sep, 2022 | 13:15h | UTC
Commentary on Twitter
Proposed classification of Multisystem inflammatory syndrome in #neonates (MIS-N)
Clinical features
Treatment and immunological mechanisms#MISC #covid19 #PIMSTS #PedsICU#NeoEBM @DrSBagci #NeoTwitter #Neonatology @DrKenRemy1 @ChrisCarrollMD @lizWWyld https://t.co/tDuM51GMr4 pic.twitter.com/PNobOOzevX— Yonca Bulut M.D. (@yoncabulutmd) September 6, 2022
Under a http://creativecommons.org/licenses/by/4.0/ License
Review | Nutritional support for pediatric severe traumatic brain injury.
14 Sep, 2022 | 13:04h | UTCNutritional Support for Pediatric Severe Traumatic Brain Injury – Frontiers in Pediatrics
Systematic Review | Long-term outcomes after non-traumatic out-of-hospital cardiac arrest in pediatric patients.
11 Sep, 2022 | 22:30h | UTC
Review | COVID-19 in children.
8 Sep, 2022 | 14:43h | UTCCOVID-19 in Children – Pediatric Clinics of North America
Pediatric infective endocarditis: a literature review.
8 Sep, 2022 | 14:31h | UTCPediatric Infective Endocarditis: A Literature Review – Journal of Clinical Medicine
Brief Review | What’s new in pediatric ventilator liberation?
5 Sep, 2022 | 14:29h | UTCWhat’s new in paediatric ventilator liberation? – Intensive Care Medicine
Commentary on Twitter
Pediatric ventilator liberation, update
⚙️ assess/adjustment of MV & sedation
⚙️ prepare
⚙️ extubate
⚙️ support
Many questions unanswered! peri-extubation steroids, criteria for NIV after extubation, post-extubation rescue HFNC vs CPAP.#PedsICU #FOAMcc
?️ https://t.co/MGPStTvZh2 pic.twitter.com/AySzk9blS5— Intensive Care Medicine (@yourICM) September 2, 2022
Perspective | Should less invasive surfactant administration (LISA) become routine practice in US neonatal units?
29 Aug, 2022 | 11:59h | UTCRelated:
Measuring quality of dying, death and end-of-life care for children and young people: a scoping review of available tools.
26 Aug, 2022 | 13:14h | UTC
Hospitalizations for unintentional cannabis poisonings among Canadian children surged after legalization.
25 Aug, 2022 | 12:07h | UTCOriginal Study: Edible Cannabis Legalization and Unintentional Poisonings in Children – New England Journal of Medicine ($)
AAP Updated Clinical Report | The use of systemic and topical fluoroquinolones.
17 Aug, 2022 | 14:19h | UTCThe Use of Systemic and Topical Fluoroquinolones – Pediatrics
International clinical practice guidelines for pediatric ventilator liberation.
16 Aug, 2022 | 13:56h | UTC
NICE Guideline | Urinary tract infection in under 16s: diagnosis and management.
15 Aug, 2022 | 12:34h | UTC
Pediatric acute liver failure: reexamining key clinical features, current management, and research prospects.
12 Aug, 2022 | 14:17h | UTC
AAP Guideline Update | Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.
9 Aug, 2022 | 13:00h | UTC
M-A | The outcome of post-cardiotomy extracorporeal membrane oxygenation in neonates and pediatric patients.
4 Aug, 2022 | 13:48h | UTC