Pediatrics (all articles)
CDC Report: COVID-19 vaccine safety in children aged 5–11 Years.
9 Jan, 2022 | 01:09h | UTCCommentary: COVID-19 vaccine appears safe in children aged 5–11 Years – News Medical
Commentary on Twitter
Early vaccine safety data for children ages 5–11 years old found that reactions such as fatigue and headaches were commonly reported following Pfizer-BioNTech #COVID19 vaccine. Everyone ages 5 years & older should get vaccinated as soon as possible. https://t.co/D66QgLRWni pic.twitter.com/8I48L5GmcG
— MMWR (@CDCMMWR) December 30, 2021
New CDC Guidance shortens isolation and quarantine period for Covid-19; patients that tested positive should isolate for 5 days and, if asymptomatic after this period, can leave isolation if they can continue to mask for 5 days to minimize the risk of infecting others.
9 Jan, 2022 | 01:13h | UTCSee also: Quarantine and Isolation – Centers for Disease Control and Prevention
Commentaries:
Facing criticism, CDC updates Covid-19 isolation recommendations with guidance on testing – CNN
CDC posts rationale for shorter isolation, quarantine – Associated Press
Covid-19: CDC shortens isolation period as US cases hit record high – The BMJ
Shortened CDC COVID isolation guide draws sharply mixed reviews – CIDRAP
New CDC isolation guidelines raise concerns among health experts – NPR
CDC Reduces Recommended Isolation Time for People With COVID-19 – HealthDay
COVID isolation and quarantine period for general population shortened by CDC – News Medical
CDC shortens recommended Covid-19 isolation and quarantine time – CNN
CDC cuts the recommended isolation and quarantine periods for coronavirus infections – NPR
US officials recommend shorter COVID isolation, quarantine – Associated Press
See new recommendations from other countries:
Covid: Self-isolation cut from 10 days to seven with negative tests – BBC
CDC Study: A test to stay strategy (allowing close contacts with masked COVID-19 exposures to remain in school) was very efficacious in preventing further school spread and allowed children to stay in the classroom as an alternative to home quarantine.
9 Jan, 2022 | 01:07h | UTCRelated CDC Guidance:
What You Should Know About COVID-19 Testing in Schools – Centers for Disease Control and Prevention
Commentary: ‘Test-to-stay’ works to keep students in school safely, CDC director says – CNN
Related:
Instead of quarantine for Covid-exposed students, some schools are trying test-to-stay.
Opinion | Data from routine Covid testing can help schools stay open this year.
Commentary on Twitter
Although vaccination is the best way to protect against #COVID19 for those aged 5 and up, schools might consider Test to Stay strategy for allowing close contacts who are not fully vaccinated to remain in the classroom. Learn more in a new @CDCMMWR: https://t.co/3m64vomRDh. pic.twitter.com/AAENAdxJ1y
— CDC (@CDCgov) December 17, 2021
[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.
9 Jan, 2022 | 01:05h | UTCRisk of myocarditis following sequential COVID-19 vaccinations by age and sex – medRxiv
Note: this study is an updated analysis of a recent study published in Nature Medicine; see below:
New AAP Guidance recommends routine HIV screening to all youth 15 years or older.
8 Jan, 2022 | 23:13h | UTCCommentary: Pediatricians Can Play Key Role in HIV Testing, Prophylaxis – HealthDay
RCT: Low-cost, easy to take antiretroviral treatment based on Dolutegravir as first- or second-Line therapy found to be non-inferior to standard care for treating HIV-1 infection in children.
8 Jan, 2022 | 23:07h | UTCDolutegravir as First- or Second-Line Treatment for HIV-1 Infection in Children – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Easy-to-take medicine better at suppressing HIV in children – University College London
Commentaries on Twitter
Dolutegravir-based antiretroviral therapy was compared with standard care in children and adolescents starting first- or second-line therapy for HIV type 1 infection. Dolutegravir-based ART was superior to standard-care ART. https://t.co/PP0XaEVswO pic.twitter.com/pQvhjdXcUk
— NEJM (@NEJM) December 29, 2021
Visual Abstract: Dolutegravir as First- or Second-Line HIV Treatment in Children https://t.co/2RIg9uH2V1 pic.twitter.com/mDr1Z6l6CJ
— NEJM (@NEJM) January 4, 2022
AAP Interim guidance on supporting the emotional and behavioral health needs of children, adolescents, and families during the COVID-19 pandemic.
17 Dec, 2021 | 09:57h | UTCCommentary: AAP Issues Guidance for Children’s Emotional Needs During COVID-19 – HealthDay
NICE Guideline | Fever in under 5s: assessment and initial management.
17 Dec, 2021 | 08:44h | UTCRelated: AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.
Sepsis in children: state-of-the-art treatment.
16 Dec, 2021 | 08:56h | UTCSepsis in children: state-of-the-art treatment – Therapeutic Advances in Infectious Disease
Antibiotics in critically ill children—a narrative review on different aspects of a rational approach.
16 Dec, 2021 | 08:53h | UTC
Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.
15 Dec, 2021 | 08:43h | UTCNews release: COVID-19 infection, more likely than vaccines, to cause rare cardiovascular complications – University of Oxford
Commentaries on Twitter
Hugely important work from @JuliaHCox and colleagues:
In people <40, Pfizer carries a much lower risk of myocarditis than either Moderna **or SARS-CoV-2 infection** (annotations added)https://t.co/wqRts3ALqy pic.twitter.com/fnn1T39h1b
— David Juurlink (@DavidJuurlink) December 14, 2021
A case series published in @NatureMedicine shows an increased risk of myocarditis after receiving the Astra-Zeneca-Oxford, Pfizer-BioNTech and the Moderna COVID-19 vaccines, but SARS-CoV-2 infection carried a greater risk of myocarditis. https://t.co/6y7pZlJN70 pic.twitter.com/cBlKz9sUkg
— Nature Portfolio (@NaturePortfolio) December 14, 2021
Just published @NatureMedicine
The most comprehensive assessment of the rare events of myocarditis, pericarditis, arrhythmias after COVID and AZ, mRNA vaccineshttps://t.co/0bEdMJSLXg pic.twitter.com/eC5JOx0CmG— Eric Topol (@EricTopol) December 14, 2021
Position Paper: Diagnosis, management, and prevention of button battery ingestion in childhood.
15 Dec, 2021 | 08:32h | UTCVisual summary: Diagnosis, Management, and Prevention of Button Battery Ingestion in Childhood
Commentary on Twitter (thread – click for more)
Button battery ingestion in children⚠️: Important🆕 guidelines for diagnosis and management from @ESPGHANSociety #GITwitter https://t.co/TQ1rfjQOpShttps://t.co/fxzzCEl2F2
— ESGE (@ESGE_news) December 14, 2021
RCT: In preterm infants with respiratory distress syndrome, surfactant administration via a thin catheter did not improve outcomes.
15 Dec, 2021 | 08:26h | UTCEffect of Minimally Invasive Surfactant Therapy vs Sham Treatment on Death or Bronchopulmonary Dysplasia in Preterm Infants With Respiratory Distress Syndrome: The OPTIMIST-A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Minimally Invasive Surfactant Therapy to Prevent Bronchopulmonary Dysplasia in Extremely Preterm Infants – JAMA (free for a limited period)
Retrospective study: antimicrobial susceptibility profiles among neonatal early-onset sepsis (EOS) pathogens – “The vast majority of contemporary EOS pathogens are susceptible to the combination of ampicillin and gentamicin”.
14 Dec, 2021 | 08:46h | UTC
Commentary on Twitter
Are bacteria responsible for early-onset sepsis susceptible to empiric antibiotic therapy used in NICU?
A new @NICHD_NIH study by @dus10flan published in @PIDJournal #neoEBM #EBNEOAlertshttps://t.co/6HJf4ZgAGa pic.twitter.com/pGMfbj3DQ6
— Evidence-Based Neo (@EBNEO) December 13, 2021
NICE Guideline | Inducing labor.
13 Dec, 2021 | 08:55h | UTCInducing labour – National Institute for Health and Care Excellence
Two-year follow up of randomized trial shows delaying umbilical cord clamping saves preterm babies’ lives.
13 Dec, 2021 | 08:46h | UTCNews Release: Two-year follow up shows delaying umbilical cord clamping saves babies’ lives – University of Sydney
Related:
Commentaries on Twitter
https://twitter.com/LancetChildAdol/status/1468733380510449667
https://twitter.com/EBNEO/status/1469959007955787781
Non-inferiority randomized trial showed radiotherapy can be safely omitted in many children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma.
10 Dec, 2021 | 10:04h | UTC
Systematic Review: Antibiotics for adults and children with sore throats.
10 Dec, 2021 | 10:02h | UTCSummary: Antibiotics for adults and children with sore throats – Cochrane Library
Original Research: Antibiotics for treatment of sore throat in children and adults – Cochrane Library
RCT: Among children between the ages of 6 and 11 years with uncontrolled moderate-to-severe asthma, add-on Dupilumab reduced exacerbations and improved lung function.
9 Dec, 2021 | 10:21h | UTCDupilumab in Children with Uncontrolled Moderate-to-Severe Asthma – New England Journal of Medicine
[Preprint] Risk of Hospitalization, severe disease, and mortality due to COVID-19 in children with SARS-CoV-2 infection in Germany – “overall hospitalization rate associated with SARS-CoV-2 infection was 35.9 per 10,000 children, ICU admission rate was 1.7 per 10,000 and case fatality was 0.09 per 10,000”.
8 Dec, 2021 | 10:18h | UTCRelated:
Review: Should children under 12 years of age be vaccinated against COVID-19?
Bronchiolitis: evidence and guidance for practice.
8 Dec, 2021 | 09:55h | UTCBronchiolitis: evidence and guidance for practice – Evidently Cochrane
Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.
7 Dec, 2021 | 10:19h | UTCNews Release: Young people recover quickly from rare myocarditis side effect of COVID-19 vaccine – American Heart Association
Review of 4,470 cases of Multisystem Inflammatory Syndrome in Children in the US.
7 Dec, 2021 | 10:08h | UTCRelated:
An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.
Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).
Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.
Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.
Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children
Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)
SR: Multisystem inflammatory syndrome in children related to COVID-19
Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance.
7 Dec, 2021 | 08:47h | UTC
The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019.
5 Dec, 2021 | 23:09h | UTCInvited Commentary: Burden of cancer in adolescents and young adults – The Lancet Oncology


