Pain Medicine
AAOS Guideline: Pharmacologic, physical, and cognitive pain alleviation for musculoskeletal extremity/pelvis surgery.
5 Aug, 2021 | 08:49h | UTCEvidence summary: Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery
Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”
4 Aug, 2021 | 09:07h | UTCSee also:
Commentary:
More evidence needed to back cannabis as pain treatment, says review – Imperial College London
Medicinal cannabis to manage chronic pain? We don’t have evidence it works – The Conversation
Related:
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
Cohort study: Evidence of a potentially inappropriate and harmful prescribing cascade of gabapentinoid followed by a diuretic among older adults with lower back pain.
29 Jul, 2021 | 11:02h | UTCEvidence of a gabapentinoid and diuretic prescribing cascade among older adults with lower back pain – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
Related:
Are you the victim of a prescribing cascade?
Prescribing Cascade in a Cardiology Practice
Review: The routes of administration for acute postoperative pain medication.
22 Jul, 2021 | 10:46h | UTCThe Routes of Administration for Acute Postoperative Pain Medication – Pain and Therapy
RCT: Progressive exercise compared with best practice advice, with or without corticosteroid injection, for the treatment of patients with rotator cuff disorders.
22 Jul, 2021 | 10:42h | UTCCommentaries: Optimising treatment for patients with rotator cuff disorders – The Lancet (free registration required)
Commentary on Twitter (thread – click for more)
The much-anticipated GRASP trial for rotator cuff pain has just been published showing steroid injections have a small short-lasting benefit, and that physio led exercise was no better than patient led exercise… Here's my short Twitter review… 1/12 https://t.co/1TFYGoAi7X
— The Sp⚽️rts Physio (@AdamMeakins) July 13, 2021
Tramadol: Where do we go from here? – “Tramadol’s unpredictability, unique potential harms, and lack of advantage over other opioids or NSAIDs are now well recognized”.
15 Jul, 2021 | 09:14h | UTC[131] Tramadol: Where do we go from here? – Therapeutic Initiative
RCT: Comparison of nebulized ketamine at three different dosing regimens for treating painful conditions in the emergency department.
13 Jul, 2021 | 09:22h | UTCComparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the Emergency Department: A Prospective, Randomized, Double-Blind Clinical Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Nebulized Ketamine for pain in the ED? No way…Well- here you go-Comparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the ED. https://t.co/v3UT0Y0LdU #FOAMed #FOAMems #FOAMtox #FOAMcc #FOAMpharm
— Sergey Motov (@painfreeED) July 3, 2021
M-A: Little benefit from muscle relaxants for adults with non-specific low back pain.
9 Jul, 2021 | 10:02h | UTCCommentary: New analysis finds muscle relaxant drugs to be largely ineffective for low back pain – News Medical
Related studies: M-A: Effectiveness of treatments for acute and subacute mechanical non-specific low back pain AND RCT: Little benefit from osteopathic manipulative treatment on activity limitations in patients with nonspecific subacute and chronic low back pain AND M-A: Little benefit from antidepressants for low back pain AND Meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis AND ACP/AAFP Guideline: Nonpharmacologic and pharmacologic management of acute pain from non–low back, musculoskeletal injuries in adults
Commentaries on Twitter
Muscle relaxants are largely ineffective for #lowback #pain. They might increase the risk of side effects.
Published today in @bmj_latest ⬇️
Proud to be a part of this excellent team led by @AidanCashin
Paper: https://t.co/4p7gd7PJIe pic.twitter.com/3CLvL7JUfI
— Hayley Leake (@HayleyLeake) July 8, 2021
This systematic review found very low certainty evidence that muscle relaxant drugs for the treatment of acute low back pain might provide a small and not clinically meaningful improvement in pain intensity at two weeks or less @Pain_NeuRa https://t.co/HGwN4Oekrq
— The BMJ (@bmj_latest) July 8, 2021
Systematic Review: Pre‐emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery.
9 Jul, 2021 | 09:50h | UTC
RCT: Pectoral nerve blocks for breast augmentation surgery.
7 Jul, 2021 | 08:41h | UTCPectoral Nerve Blocks for Breast Augmentation Surgery: A Randomized, Double-blind, Dual-centered Controlled Trial – Anesthesiology (link to abstract – $ for full-text)
Commentary on Twitter
Better pain relief using PECS blocks in breast augmentation surgery. https://t.co/T0SIyR7zFn pic.twitter.com/4rrbj6eTFk
— Anesthesiology (@_Anesthesiology) June 29, 2021
M-A: The efficacy of systemic glucocorticosteroids for pain in rheumatoid arthritis.
6 Jul, 2021 | 09:54h | UTC
RCT: Consuming a diet with more fish fats, less vegetable oils can reduce migraine headaches.
5 Jul, 2021 | 01:51h | UTCNews release: Consuming a diet with more fish fats, less vegetable oils can reduce migraine headaches – NIH News Releases
Original study: Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial – The BMJ
Editorial: Dietary omega 3 fatty acids for migraine
Clinical Practice Guideline: Opioid Prescribing for Analgesia After Common Otolaryngology Operations.
5 Jul, 2021 | 01:19h | UTCOtolaryngology–Head and Neck Surgery
Commentary: AAO/HNS Issue Guideline for Opioid Use After Otolaryngologic Surgery – HealthDay
RCT: Safety and efficacy of occipital nerve stimulation for attack prevention in medically intractable chronic cluster headache.
5 Jul, 2021 | 01:24h | UTCSafety and efficacy of occipital nerve stimulation for attack prevention in medically intractable chronic cluster headache (ICON): a randomised, double-blind, multicentre, phase 3, electrical dose-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
Commentary: Nerve stimulation effective in patients with untreatable cluster headaches – Leiden University
Complex Regional Pain Syndrome: A Comprehensive Review
2 Jul, 2021 | 11:13h | UTCComplex Regional Pain Syndrome: A Comprehensive Review – Pain and Therapy
Editorial | Physiotherapists can reduce overuse by Choosing Wisely.
23 Jun, 2021 | 10:11h | UTCPhysiotherapists can reduce overuse by Choosing Wisely – Journal of Physiotherapy
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
RCT: Effects of intravenous Eptinezumab vs. placebo on headache pain and most bothersome symptom when initiated during a migraine attack.
18 Jun, 2021 | 08:16h | UTCEffects of Intraven.ous Eptinezumab vs Placebo on Headache Pain and Most Bothersome Symptom When Initiated During a Migraine Attack: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Acute Treatment for Migraine: Contemporary Treatments and Future Directions (free for a limited period)
Commentary: Migraine Prevention Drug Eptinezumab Shows Efficacy in Treating Acute Attacks – Physician’s Weekly
Commentary on Twitter (thread – click for more)
Science marches breathlessly forward – or, at least tries to expand its indication.
Anti–calcitonin gene-related peptide antibody infusion, again, vs. placebo.
— Ryan Radecki, MD MS (@emlitofnote) June 17, 2021
M-A: Acute treatments for episodic migraine in adults.
18 Jun, 2021 | 08:18h | UTCAcute Treatments for Episodic Migraine in Adults: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Editorial: Acute Treatment for Migraine: Contemporary Treatments and Future Directions (free for a limited period)
Commentary on Twitter (thread – click for more)
Science marches breathlessly forward – or, at least tries to expand its indication.
Anti–calcitonin gene-related peptide antibody infusion, again, vs. placebo.
— Ryan Radecki, MD MS (@emlitofnote) June 17, 2021
Randomized, sham-controlled pilot study: percutaneous peripheral nerve stimulation (neuromodulation) for postoperative pain.
16 Jun, 2021 | 08:17h | UTCCommentary: Peripheral Nerve Stimulation May Cut Pain After Orthopedic Surgery – HealthDay
M-A: Ibuprofen and other NSAIDs superior to codeine for managing outpatient postoperative pain.
15 Jun, 2021 | 08:55h | UTCOriginal Article: Managing postoperative pain in adult outpatients: a systematic review and meta-analysis comparing codeine with NSAIDs – Canadian Medical Association Journal
M-A: Effectiveness of telerehabilitation in physical therapist practice.
10 Jun, 2021 | 09:29h | UTC
RCT: No benefit from posterior quadratus lumborum block in total hip arthroplasty.
6 Jun, 2021 | 23:35h | UTC
Commentary on Twitter
In the context of a multimodal postoperative analgesic strategy, providing a quadratus lumborum block using ropivacaine resulted in no less morphine consumption or pain in the first 24 postoperative hours compared to saline injection #visualabstract https://t.co/cvxuQ9AQPQ pic.twitter.com/HP5EwrKagx
— Anesthesiology (@_Anesthesiology) April 20, 2021
EULAR recommendations for intra-articular therapies.
28 May, 2021 | 08:16h | UTCEULAR recommendations for intra-articular therapies – Annals of Rheumatic Diseases
Systematic review: Prognostic factors for pain chronicity in low back pain – “Higher pain intensity, higher body weight, carrying heavy loads at work, difficult working positions, and depression were the most frequently observed risk factors for chronic low back pain”
20 May, 2021 | 08:32h | UTCPrognostic factors for pain chronicity in low back pain: a systematic review – Pain Reports
The catastrophization effects of an MRI report on the patient and surgeon and the benefits of ‘clinical reporting’: results from an RCT and blinded trials.
19 May, 2021 | 08:25h | UTCRelated: You cannot unsee your MRI report AND Direct communication between radiologists and patients improves the quality of imaging reports – European Radiology
Commentary on Twitter
https://twitter.com/hjluks/status/1392151713700794374