Pain Medicine
RCT: Ketamine administration in patients with acute painful sickle cell crisis was effective for pain control and reduced the cumulative morphine dose in the emergency department.
2 Sep, 2021 | 08:11h | UTCKetamine Administration for Acute Painful Sickle Cell Crisis: A Randomized Controlled Trial – Academic Emergency Medicine (link to abstract – $ for full-text)
Review: The role of regional analgesia in personalized postoperative pain management.
26 Aug, 2021 | 08:24h | UTC
RCT: A single-session of pain management skills intervention was noninferior to 8 sessions of cognitive behavioral therapy in adults with chronic low back pain.
24 Aug, 2021 | 08:39h | UTCCommentaries:
New approach effectively relieves chronic low back pain – Stanford Medicine
Commentary on Twitter
NEW STUDY: Our Empowered Relief trial just published!
A *single-session* pain relief skills class was non-inferior to 8-session CBT for pain & symptom reduction at 3 months post-treatmenthttps://t.co/HYmWNkxUoR via @JAMANetworkOpen part of @JAMANetwork
funded by @NIH_NCCIH
— Beth Darnall, PhD (@BethDarnall) August 16, 2021
Systematic review: Kinesio taping provides little or no benefit for rotator cuff disease.
16 Aug, 2021 | 00:52h | UTCKinesio taping for rotator cuff disease – Cochrane Library
Summary: Kinesio taping for rotator cuff disease – Cochrane Library
Commentary on Twitter
Kinesio taping is one possible conservative treatment for rotator cuff disease (painful shoulder disorders).
Is it effective & what possible harms might it have?
Read about the latest Cochrane evidence from @CochraneMSK: https://t.co/itvdrUuIBm #KinesioTaping #KinesioTape pic.twitter.com/hXqvjOCgf8
— Cochrane UK (@CochraneUK) August 14, 2021
Guideline: Non-surgical interventions for lumbar spinal stenosis leading to neurogenic claudication.
13 Aug, 2021 | 09:03h | UTC
RCT: Decompression alone is non-inferior to decompression with fusion in patients with degenerative lumbar spondylolisthesis.
6 Aug, 2021 | 09:54h | UTCCommentary: Decompression Noninferior for Degenerative Spondylolisthesis – HealthDay
M-A: Pharmacotherapy for the prevention of chronic pain after surgery in adults.
6 Aug, 2021 | 09:51h | UTC
Commentary on Twitter
Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults: An Updated Systematic Review and Meta-analysis https://t.co/DzILWovtGG #visualabstract pic.twitter.com/A8JIxKl942
— Anesthesiology journal (@_Anesthesiology) August 5, 2021
AAOS Guideline: Pharmacologic, physical, and cognitive pain alleviation for musculoskeletal extremity/pelvis surgery.
5 Aug, 2021 | 08:49h | UTCEvidence summary: Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery
Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”
4 Aug, 2021 | 09:07h | UTCSee also:
Commentary:
More evidence needed to back cannabis as pain treatment, says review – Imperial College London
Medicinal cannabis to manage chronic pain? We don’t have evidence it works – The Conversation
Related:
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
Cohort study: Evidence of a potentially inappropriate and harmful prescribing cascade of gabapentinoid followed by a diuretic among older adults with lower back pain.
29 Jul, 2021 | 11:02h | UTCEvidence of a gabapentinoid and diuretic prescribing cascade among older adults with lower back pain – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
Related:
Are you the victim of a prescribing cascade?
Prescribing Cascade in a Cardiology Practice
Review: The routes of administration for acute postoperative pain medication.
22 Jul, 2021 | 10:46h | UTCThe Routes of Administration for Acute Postoperative Pain Medication – Pain and Therapy
RCT: Progressive exercise compared with best practice advice, with or without corticosteroid injection, for the treatment of patients with rotator cuff disorders.
22 Jul, 2021 | 10:42h | UTCCommentaries: Optimising treatment for patients with rotator cuff disorders – The Lancet (free registration required)
Commentary on Twitter (thread – click for more)
The much-anticipated GRASP trial for rotator cuff pain has just been published showing steroid injections have a small short-lasting benefit, and that physio led exercise was no better than patient led exercise… Here's my short Twitter review… 1/12 https://t.co/1TFYGoAi7X
— The Sp⚽️rts Physio (@AdamMeakins) July 13, 2021
Tramadol: Where do we go from here? – “Tramadol’s unpredictability, unique potential harms, and lack of advantage over other opioids or NSAIDs are now well recognized”.
15 Jul, 2021 | 09:14h | UTC[131] Tramadol: Where do we go from here? – Therapeutic Initiative
RCT: Comparison of nebulized ketamine at three different dosing regimens for treating painful conditions in the emergency department.
13 Jul, 2021 | 09:22h | UTCComparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the Emergency Department: A Prospective, Randomized, Double-Blind Clinical Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Nebulized Ketamine for pain in the ED? No way…Well- here you go-Comparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the ED. https://t.co/v3UT0Y0LdU #FOAMed #FOAMems #FOAMtox #FOAMcc #FOAMpharm
— Sergey Motov (@painfreeED) July 3, 2021
M-A: Little benefit from muscle relaxants for adults with non-specific low back pain.
9 Jul, 2021 | 10:02h | UTCCommentary: New analysis finds muscle relaxant drugs to be largely ineffective for low back pain – News Medical
Related studies: M-A: Effectiveness of treatments for acute and subacute mechanical non-specific low back pain AND RCT: Little benefit from osteopathic manipulative treatment on activity limitations in patients with nonspecific subacute and chronic low back pain AND M-A: Little benefit from antidepressants for low back pain AND Meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis AND ACP/AAFP Guideline: Nonpharmacologic and pharmacologic management of acute pain from non–low back, musculoskeletal injuries in adults
Commentaries on Twitter
Muscle relaxants are largely ineffective for #lowback #pain. They might increase the risk of side effects.
Published today in @bmj_latest ⬇️
Proud to be a part of this excellent team led by @AidanCashin
Paper: https://t.co/4p7gd7PJIe pic.twitter.com/3CLvL7JUfI
— Hayley Leake (@HayleyLeake) July 8, 2021
This systematic review found very low certainty evidence that muscle relaxant drugs for the treatment of acute low back pain might provide a small and not clinically meaningful improvement in pain intensity at two weeks or less @Pain_NeuRa https://t.co/HGwN4Oekrq
— The BMJ (@bmj_latest) July 8, 2021
Systematic Review: Pre‐emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery.
9 Jul, 2021 | 09:50h | UTC
RCT: Pectoral nerve blocks for breast augmentation surgery.
7 Jul, 2021 | 08:41h | UTCPectoral Nerve Blocks for Breast Augmentation Surgery: A Randomized, Double-blind, Dual-centered Controlled Trial – Anesthesiology (link to abstract – $ for full-text)
Commentary on Twitter
Better pain relief using PECS blocks in breast augmentation surgery. https://t.co/T0SIyR7zFn pic.twitter.com/4rrbj6eTFk
— Anesthesiology journal (@_Anesthesiology) June 29, 2021
M-A: The efficacy of systemic glucocorticosteroids for pain in rheumatoid arthritis.
6 Jul, 2021 | 09:54h | UTC
RCT: Consuming a diet with more fish fats, less vegetable oils can reduce migraine headaches.
5 Jul, 2021 | 01:51h | UTCNews release: Consuming a diet with more fish fats, less vegetable oils can reduce migraine headaches – NIH News Releases
Original study: Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial – The BMJ
Editorial: Dietary omega 3 fatty acids for migraine
Clinical Practice Guideline: Opioid Prescribing for Analgesia After Common Otolaryngology Operations.
5 Jul, 2021 | 01:19h | UTCOtolaryngology–Head and Neck Surgery
Commentary: AAO/HNS Issue Guideline for Opioid Use After Otolaryngologic Surgery – HealthDay
RCT: Safety and efficacy of occipital nerve stimulation for attack prevention in medically intractable chronic cluster headache.
5 Jul, 2021 | 01:24h | UTCSafety and efficacy of occipital nerve stimulation for attack prevention in medically intractable chronic cluster headache (ICON): a randomised, double-blind, multicentre, phase 3, electrical dose-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
Commentary: Nerve stimulation effective in patients with untreatable cluster headaches – Leiden University
Complex Regional Pain Syndrome: A Comprehensive Review
2 Jul, 2021 | 11:13h | UTCComplex Regional Pain Syndrome: A Comprehensive Review – Pain and Therapy
Editorial | Physiotherapists can reduce overuse by Choosing Wisely.
23 Jun, 2021 | 10:11h | UTCPhysiotherapists can reduce overuse by Choosing Wisely – Journal of Physiotherapy
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
RCT: Effects of intravenous Eptinezumab vs. placebo on headache pain and most bothersome symptom when initiated during a migraine attack.
18 Jun, 2021 | 08:16h | UTCEffects of Intraven.ous Eptinezumab vs Placebo on Headache Pain and Most Bothersome Symptom When Initiated During a Migraine Attack: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Acute Treatment for Migraine: Contemporary Treatments and Future Directions (free for a limited period)
Commentary: Migraine Prevention Drug Eptinezumab Shows Efficacy in Treating Acute Attacks – Physician’s Weekly
Commentary on Twitter (thread – click for more)
Science marches breathlessly forward – or, at least tries to expand its indication.
Anti–calcitonin gene-related peptide antibody infusion, again, vs. placebo.
— Ryan Radecki, MD MS (@emlitofnote) June 17, 2021
M-A: Acute treatments for episodic migraine in adults.
18 Jun, 2021 | 08:18h | UTCAcute Treatments for Episodic Migraine in Adults: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Editorial: Acute Treatment for Migraine: Contemporary Treatments and Future Directions (free for a limited period)
Commentary on Twitter (thread – click for more)
Science marches breathlessly forward – or, at least tries to expand its indication.
Anti–calcitonin gene-related peptide antibody infusion, again, vs. placebo.
— Ryan Radecki, MD MS (@emlitofnote) June 17, 2021