Pain Medicine
Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.
9 Nov, 2021 | 01:17h | UTCSee also:
Related:
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
Guideline: Medical cannabis or cannabinoids for chronic pain.
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
Things We Do for No Reason: Prescribing Tramadol for Inpatients in Pain.
5 Nov, 2021 | 09:44h | UTCRelated:
Cohort Study: Chronic Use of Tramadol After Acute Pain Episode
Short Review: Ketamine for the treatment of acute pain.
2 Nov, 2021 | 02:43h | UTCKetamine for the treatment of acute pain – Canadian Medical Association Journal
Commentary on Twitter
If you manage pain in hospital, low-dose ketamine should be in your toolkit. And not just in the ED.
Quick overview with @WKSilverstein & @JonZipursky in @CMAJ: https://t.co/w5h3vIMiEK pic.twitter.com/gVO7W9dcYY
— David Juurlink (@DavidJuurlink) November 1, 2021
RCT: Extended follow-up of local steroid injection for carpal tunnel syndrome.
28 Oct, 2021 | 09:46h | UTC
Commentary on Twitter
In carpal tunnel syndrome, this randomized trial of local steroid vs placebo injection shows similar symptom severity score improvement but a significant small reduction in rate of and longer time to surgery after steroid. @IsamAtroshi @jonasranstam https://t.co/s5LibRnFaV
— JAMA Network Open (@JAMANetworkOpen) October 22, 2021
Five-year follow-up of RCT: Arthroscopic subacromial decompression provided no benefit over diagnostic arthroscopy or exercise therapy on return to work in patients with shoulder impingement syndrome.
21 Oct, 2021 | 09:54h | UTCRelated:
Randomized Trial: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement
Research: Arthroscopic subacromial decompression for subacromial shoulder pain
Systematic Review: Subacromial Decompression Surgery for Rotator Cuff Disease
Systematic Review: Surgery for Rotator Cuff Tears
Large observational study suggests Tramadol is associated with increased risk of adverse outcomes compared to Codeine.
20 Oct, 2021 | 10:11h | UTCAssociation of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Clinical Outcomes – JAMA (free for a limited period)
Editorial: Tramadol, Codeine, and Risk of Adverse Outcomes – JAMA (free for a limited period)
M-A: Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis – although Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be most effective treatments, topical diclofenac 70-81 mg/day is safer and should be considered as first line treatment.
17 Oct, 2021 | 21:14h | UTCNews release: Topical pain-killers more effective, safer than opioids for knee osteoarthritis pain – St. Michael’s Hospital
Commentary: Network meta-analysis compares analgesic regimens for osteoarthritis – medwire News
Commentary on Twitter
Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be the most effective oral NSAIDs for knee and hip osteoarthritis pain and physical function, but might not be appropriate in the presence of comorbidities or for long term use, concludes #BMJResearchhttps://t.co/rrtX3BnQE5
— The BMJ (@bmj_latest) October 16, 2021
RCT: After third molar surgery, Ibuprofen doses above 400 mg did not significantly increase the analgesic effect, and Paracetamol 1000/codeine 60 mg was not more effective than ibuprofen 400 mg.
17 Oct, 2021 | 21:16h | UTC
Podcast: Acute Pain Management for the Hospitalist.
14 Oct, 2021 | 09:47h | UTC#299 Acute Pain Management for the Hospitalist – The Curbsiders
M-A: New pharmacologic agents (Ditans and Gepants) are not as good as triptans for treating migraines.
13 Oct, 2021 | 01:17h | UTCCommentary: Migraine: Older Drugs May Be Best Bet for Lessening Pain – Physician’s Weekly
Commentary on Twitter
This systematic review and meta-analysis found that ditans and gepants were associated with less efficacy compared with triptans, whereas gepants were associated with fewer adverse events compared with triptans for migraine treatment. https://t.co/PFCHg4MZ8r
— JAMA Network Open (@JAMANetworkOpen) October 11, 2021
Systematic Review: Is exercise an effective therapy to treat long-lasting low back pain?
3 Oct, 2021 | 22:32h | UTCSummary: Is exercise an effective therapy to treat long-lasting low back pain? – Cochrane Library
Original Study: Exercise therapy for chronic low back pain – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1444221879502483456
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
1 Oct, 2021 | 10:07h | UTCRelated studies:
Cannabinol and Sleep: Separating Fact from Fiction – Cannabis and Cannabinoid Research
Medical Cannabis and Cannabinoids for Impaired Sleep: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – Sleep (link to abstract – $ for full-text)
Guideline Synopsis: The Non-Surgical Management of Hip and Knee Osteoarthritis.
1 Oct, 2021 | 10:00h | UTC
RCT: Neurolytic splanchnic nerve block and pain relief, survival, and quality of life in unresectable pancreatic cancer.
30 Sep, 2021 | 10:16h | UTC
Commentary on Twitter
Neurolytic Splanchnic Nerve Block and Pain Relief, Survival, and Quality of Life in Unresectable Pancreatic Cancer: A Randomized Controlled Trial https://t.co/xa9sPAdQu1 pic.twitter.com/gi74fdDSfl
— Anesthesiology (@_Anesthesiology) August 30, 2021
Consensus Statement: Paracetamol use during pregnancy — a call for precautionary action – “Pregnant women should minimize risk by using the lowest effective APAP dose for the shortest possible time”.
26 Sep, 2021 | 22:02h | UTCParacetamol use during pregnancy — a call for precautionary action – Nature Reviews Endocrinology
Editorial: Caution needed: paracetamol use in pregnancy – Nature Reviews Endocrinology
Commentaries:
New research cautions about possible risks of acetaminophen use during pregnancy – STAT
Expert reaction to statement on paracetamol use during pregnancy – Science Media Centre
A Common Pain Relief Med Used in Pregnancy Should Be Taken with Caution, Experts Warn – ScienceAlert
Commentary on Twitter
New content online: Paracetamol use during pregnancy — a call for precautionary action https://t.co/FhsB5KdRs0 pic.twitter.com/8BQUUWeTbN
— Nature Reviews Endocrinology (@NatureRevEndo) September 23, 2021
AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee.
21 Sep, 2021 | 09:03h | UTCNews release: AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee – American Academy of Orthopaedic Surgeons
Guideline summary: Management of Osteoarthritis of the Knee (Non-Arthroplasty) (3rd Edition) – American Academy of Orthopaedic Surgeons
Full paper: Management of Osteoarthritis of the Knee (Non-Arthroplasty) Evidence-Based Clinical Practice Guideline
Systematic Review: Interventional treatments for acute and chronic pain.
17 Sep, 2021 | 10:01h | UTC
Guideline: Medical cannabis or cannabinoids for chronic pain.
10 Sep, 2021 | 05:22h | UTCMedical cannabis or cannabinoids for chronic pain: a clinical practice guideline – The BMJ
Editorial: Medical cannabis for chronic pain – The BMJ
Related: Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.” (several resources on the subject)
Commentary on Twitter
A panel of international experts make a weak recommendation for a trial of non-inhaled medical cannabis or cannabinoids for people living with chronic pain, if standard care is not sufficient
Guideline includes a visual summary #BMJInfographic @will_s_t https://t.co/25ML4DZcvz pic.twitter.com/mjbDOyYVLL
— The BMJ (@bmj_latest) September 9, 2021
RCT: Ketamine administration in patients with acute painful sickle cell crisis was effective for pain control and reduced the cumulative morphine dose in the emergency department.
2 Sep, 2021 | 08:11h | UTCKetamine Administration for Acute Painful Sickle Cell Crisis: A Randomized Controlled Trial – Academic Emergency Medicine (link to abstract – $ for full-text)
Review: The role of regional analgesia in personalized postoperative pain management.
26 Aug, 2021 | 08:24h | UTC
RCT: A single-session of pain management skills intervention was noninferior to 8 sessions of cognitive behavioral therapy in adults with chronic low back pain.
24 Aug, 2021 | 08:39h | UTCCommentaries:
New approach effectively relieves chronic low back pain – Stanford Medicine
Commentary on Twitter
NEW STUDY: Our Empowered Relief trial just published!
A *single-session* pain relief skills class was non-inferior to 8-session CBT for pain & symptom reduction at 3 months post-treatmenthttps://t.co/HYmWNkxUoR via @JAMANetworkOpen part of @JAMANetwork
funded by @NIH_NCCIH
— Beth Darnall, PhD (@BethDarnall) August 16, 2021
Systematic review: Kinesio taping provides little or no benefit for rotator cuff disease.
16 Aug, 2021 | 00:52h | UTCKinesio taping for rotator cuff disease – Cochrane Library
Summary: Kinesio taping for rotator cuff disease – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1426468681677254658
Guideline: Non-surgical interventions for lumbar spinal stenosis leading to neurogenic claudication.
13 Aug, 2021 | 09:03h | UTC
RCT: Decompression alone is non-inferior to decompression with fusion in patients with degenerative lumbar spondylolisthesis.
6 Aug, 2021 | 09:54h | UTCCommentary: Decompression Noninferior for Degenerative Spondylolisthesis – HealthDay
M-A: Pharmacotherapy for the prevention of chronic pain after surgery in adults.
6 Aug, 2021 | 09:51h | UTC
Commentary on Twitter
Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults: An Updated Systematic Review and Meta-analysis https://t.co/DzILWovtGG #visualabstract pic.twitter.com/A8JIxKl942
— Anesthesiology (@_Anesthesiology) August 5, 2021