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Oncology (all articles)

[Abstract Only] Randomized Trial: Ultra-hypofractionated vs. Conventionally Fractionated Radiotherapy for Prostate Cancer

30 Jun, 2019 | 17:18h | UTC

Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 

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[Abstract Only] Study: 81% of Metastatic Colorectal Cancers Seed Metastases While the Carcinoma is Clinically Undetectable

30 Jun, 2019 | 17:13h | UTC

Quantitative evidence for early metastatic seeding in colorectal cancer – Nature Genetics (link to abstract – $ for full-text)

Commentaries: Most metastatic colorectal cancers have spread before diagnosis, Stanford researchers say – Stanford Medicine (free) AND Colon cancer may be metastatic long before initial detection – UPI (free) AND Some Colorectal Cancers Are “Born To Be Bad,” Have Already Spread Long Before Diagnosis – Forbes (free)

 


Perspective: Challenging the Resistance to Palliative Care

28 Jun, 2019 | 07:42h | UTC

Survey Snapshot: Challenging the Resistance to “Palliative” – NEJM Catalyst (free)

 


International Consensus on Lesions of Uncertain Malignant Potential in the Breast (B3 lesions)

27 Jun, 2019 | 09:17h | UTC

Second International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions) – Breast Cancer Research and Treatment (free)

 


ESMO Guideline: Early Breast Cancer

24 Jun, 2019 | 01:49h | UTC

Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology (free PDF)

 


Study: Prevalence of Chronic Pain in Cancer Survivors

21 Jun, 2019 | 08:28h | UTC

Prevalence of Chronic Pain and High-Impact Chronic Pain in Cancer Survivors in the United States – JAMA Oncology (free for a limited period)

Commentaries: Nearly 5.4 million cancer survivors suffer chronic pain – American Cancer Society (free) AND One-third of cancer survivors experiences chronic pain, study says – UPI (free)

 


Small Observational Study Suggests Active Surveillance is Feasible for Small Renal Masses

20 Jun, 2019 | 05:56h | UTC

Extended Duration of Active Surveillance of Small Renal Masses: A Prospective Cohort Study – Journal of Urology (free)

Commentary: Active Surveillance Safe for Small Renal Tumors – MedPage Today (free registration required)

 


[Abstract Only] Randomized Trial: Overall Survival with a (CDK) 4/6 inhibitor plus Endocrine Therapy in Breast Cancer

19 Jun, 2019 | 07:48h | UTC

Overall Survival with Ribociclib plus Endocrine Therapy in Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: MONALEESA-7 Shows Overall Survival Benefit for Ribociclib/Endocrine Therapy – The ASCO Post (free)

 


[Abstract Only] Randomized Trial: Chemotherapy Alone vs. Chemotherapy Plus Radiation Therapy for Locally Advanced Endometrial Cancer

18 Jun, 2019 | 06:54h | UTC

Adjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Carboplatin & paclitaxel chemotherapy alone should remain standard treatment for endometrial cancer – NRG Oncology (free) AND Radiation’s Role Questioned in Stage III Uterine Cancer – MedPage Today (free registration required) AND Chemo Alone in Advanced Endometrial Cancer? – Medscape (free registration required)

 


Update Breast Cancer 2019 Part 3 – Current Developments in Early Breast Cancer: Review and Critical Assessment by an International Expert Panel

17 Jun, 2019 | 06:00h | UTC

Update Breast Cancer 2019 Part 3 – Current Developments in Early Breast Cancer: Review and Critical Assessment by an International Expert Panel – Geburtshilfe und Frauenheilkunde (free)

See also: Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) – Part 1 with Recommendations for the Screening, Diagnosis and Therapy of Breast Cancer (free) AND Update Breast Cancer 2019 Part 2 – Implementation of Novel Diagnostics and Therapeutics in Advanced Breast Cancer Patients in Clinical Practice (free)

 


Meta-analysis: Prophylactic and Therapeutic Effects of Honey on Radiochemotherapy-induced Mucositis

17 Jun, 2019 | 05:57h | UTC

Prophylactic and therapeutic effects of honey on radiochemotherapy-induced mucositis: a meta-analysis of randomized controlled trials – Supportive Care in Cancer (free)

 


ESGO–EFC Position Paper: Human Papillomavirus Vaccination

17 Jun, 2019 | 06:04h | UTC

Human papillomavirus vaccination: The ESGO–EFC position paper of the European society of Gynaecologic Oncology and the European Federation for colposcopy – European Journal of Cancer (free)

Commentary: European organizations strongly in favor of gender-neutral HPV vaccination – Univadis (free registration required)

 


2019 Japanese Guidelines for the Treatment of Colorectal Cancer

17 Jun, 2019 | 06:02h | UTC

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer – International Journal of Clinical Oncology (free)

 


Meta-Analysis: Safety and Efficacy of Aspirin for Primary Prevention of Cancer

17 Jun, 2019 | 01:44h | UTC

Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials – Journal of Cancer Research and Clinical Oncology (free)

“Our study did not find any significant reductions in cancer-related mortality or cancer incidence when compared aspirin use with placebo or no aspirin.”

 


[Abstract Only] Artificial Intelligence Algorithms vs. Human Readers for Diagnosis of Pigmented Skin Lesions

17 Jun, 2019 | 01:38h | UTC

Comparison of the accuracy of human readers versus machine-learning algorithms for pigmented skin lesion classification: an open, web-based, international, diagnostic study – The Lancet Oncology (link to abstract- $ for full-text)

Commentary: Artificial intelligence for the diagnosis of skin lesions is superior to humans – Medical University of Vienna (free)

 


Randomized Trial: Trastuzumab for 6 Months as Good as Treatment for 12 Months in Patients with HER2-positive Early Breast Cancer

17 Jun, 2019 | 01:30h | UTC

6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial – The Lancet (free)

Commentaries: Is the duration of adjuvant trastuzumab debate still clinically relevant? – The Lancet (free) AND 6 months treatment with Herceptin is as good as 12 months for preventing breast cancer return – University of Warwick (free)

 


Cohort Study: Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients with Lung Cancer

17 Jun, 2019 | 01:32h | UTC

Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients With Lung Cancer – Journal of the American College of Cardiology (free for a limited period)

Commentaries: Radiation treatment increases cardiac risk for lung cancer patients – Brigham and Women’s Hospital (free) AND Study: Radiation drives up cardiac event risk for lung cancer patients – UPI (free) AND Cardiac Radiation Can Increase Mortality in Lung Cancer Patients – MedicalResearch.com (free)

 


Cancer Treatment and Survivorship Statistics, 2019

12 Jun, 2019 | 05:38h | UTC

Cancer treatment and survivorship statistics, 2019 – CA: A Cancer Journal for Clinicians (free)

Commentaries: Cancer survivors to reach 22 million by 2030 – UPI (free) AND Cancer survivors predicted to number over 22 million by 2030 – American Cancer Society (free)

 


Consensus Paper: Management of Targeted Therapies in Cancer Patients with Chronic Kidney Disease, or on Hemodialysis

9 Jun, 2019 | 13:59h | UTC

Management of targeted therapies in cancer patients with chronic kidney disease, or on haemodialysis: An Associazione Italiana di Oncologia Medica (AIOM)/Societa’ Italiana di Nefrologia (SIN) multidisciplinary consensus position paper – Critical Reviews in Oncology/Hematology (free)

 


Review: Malignant Neoplasms of Meckel’s Diverticulum

9 Jun, 2019 | 13:23h | UTC

Malignant neoplasms of Meckel’s Diverticulum; an evidence based review – Annals of Medicine and Surgery (free)

 


Meta-Analysis: Risk of Pneumonitis and Pneumonia Associated With Immune Checkpoint Inhibitors for Solid Tumors

9 Jun, 2019 | 13:30h | UTC

Risk of Pneumonitis and Pneumonia Associated With Immune Checkpoint Inhibitors for Solid Tumors: A Systematic Review and Meta-Analysis – Frontiers in Immunology (free)

 


Guideline: Adjuvant Therapy for Resected Biliary Tract Cancer

9 Jun, 2019 | 12:58h | UTC

Adjuvant Therapy for Resected Biliary Tract Cancer: ASCO Clinical Practice Guideline – Journal of Clinical Oncology (free)

 


[Abstract Only] Randomized Trial: Lisinopril vs. Carvedilol vs. Placebo to Prevent Trastuzumab Cardiotoxicity in Patients with Breast Cancer

5 Jun, 2019 | 04:13h | UTC

Randomized Trial of Lisinopril Versus Carvedilol to Prevent Trastuzumab Cardiotoxicity in Patients With Breast Cancer – Journal of the American College of Cardiology (link to abstract – $ for full-text)

“In patients with HER2-positive breast cancer treated with trastuzumab, both lisinopril and carvedilol prevented cardiotoxicity in patients receiving anthracyclines.”

 


[Abstract Only] Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma

3 Jun, 2019 | 07:29h | UTC

Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)

 


[Abstract Only] Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer

3 Jun, 2019 | 07:31h | UTC

Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Adding Apalutamide to ADT Prolongs Survival in mCSPC – Renal & Urology News (free) AND TITAN: OS benefit seen with apalutamide in metastatic CSPC setting – Medicine Matters (free)

 


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