Oncology (all articles)
[Abstract Only] Large Observational Study Suggests Vasectomy May Increase the Risk of Prostate Cancer
3 Jun, 2019 | 07:19h | UTCVasectomy and prostate cancer risk: a 38-year nationwide cohort study – JNCI: Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentary: Vasectomy Increases Prostate Cancer Risk Over Time – Medscape (free registration required)
ASCO/SNO Joint Endorsement Summary: Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors
30 May, 2019 | 08:30h | UTCOriginal Guideline: Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines – Journal of Clinical Oncology (free)
Study: Assessment of the Clinical Benefit of Cancer Drugs Receiving Accelerated Approval
29 May, 2019 | 02:00h | UTCAssessment of the Clinical Benefit of Cancer Drugs Receiving Accelerated Approval – JAMA Internal Medicine (free for a limited period)
Related Study: An Overview of Cancer Drugs Approved by the US Food and Drug Administration Based on the Surrogate End Point of Response Rate – JAMA Internal Medicine (free for a limited period)
Invited Commentaries: An International Perspective on Drugs for Cancer: The Best of Times, the Worst of Times (free for a limited period) AND Accelerated Approval of Cancer Drugs—Righting the Ship of the US Food and Drug Administration (free for a limited period)
Commentaries: Cancer Drugs Approved Quickly Often Fail To Measure Up Later – NPR (free) AND Questions raised over cancer drugs in FDA’s accelerated approval program – CNN (free)
Randomized Trial: Similar Disease-free Survival with Laparoscopic vs. Open Distal Gastrectomy for Locally Advanced Gastric Cancer
29 May, 2019 | 01:41h | UTCEffect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer: The CLASS-01 Randomized Clinical Trial – JAMA (free for a limited period)
Cancer Control in Low- and Middle-Income Countries: Is It Time to Consider Screening?
29 May, 2019 | 01:43h | UTC“the placement of priority on early detection cannot be assumed to be effective in LMICs, where limited downstream resources may be overwhelmed by the inevitable increases in number of diagnoses.”
[Abstract Only] Randomized Trial: Effect of Vein-First vs Artery-First Surgical Technique on Circulating Tumor Cells and Survival in Patients with Non–Small Cell Lung Cancer
28 May, 2019 | 10:35h | UTCEffect of Vein-First vs Artery-First Surgical Technique on Circulating Tumor Cells and Survival in Patients With Non–Small Cell Lung Cancer: A Randomized Clinical Trial and Registry-Based Propensity Score Matching Analysis – JAMA Surgery (link to abstract – $ for full-text)
Source: EvidenceAlerts
Related Commentary on Twitter
Ligating the effluent veins first may be more consistent with cancer treatment principles and should be recommended for #lungcancer surgery https://t.co/rAz1caon8Y
— JAMA Surgery (@JAMASurgery) May 2, 2019
Review: From Molecular Mechanisms to Clinical Management of Antineoplastic Drug-Induced Cardiovascular Toxicity
28 May, 2019 | 10:22h | UTCRelated: AHA Scientific Statement on Cardio-Oncology: Vascular and Metabolic Perspectives (several guidelines on the subject)
Study: Preventable Cancer Burden Associated with Poor Diet
28 May, 2019 | 00:47h | UTCPreventable Cancer Burden Associated with Poor Diet in the United States – JNCI Cancer Spectrum (free PDF)
Commentaries: New study estimates preventable cancer burden linked to poor diet in the US – Tufts University (free) AND Poor diet may increase risk for preventable cancers – UPI (free)
Another Study Shows Increased Incidence of Colorectal Cancer in Adults Aged 40 Through 49 Years
26 May, 2019 | 19:59h | UTCTrends in Incidence and Stage at Diagnosis of Colorectal Cancer in Adults Aged 40 Through 49 Years, 1975-2015 – JAMA (free for a limited period)
Commentaries: CRC rates appear to be rising among younger adults in U.S., Europe – ACP Gastroenterology (free) AND More Younger People Getting Later Stage Colon Cancer – MedicalResearch.com (free)
Related: Two Studies Point to Increase in Colorectal Cancer Incidence in Young Adults (link to abstracts and commentaries)
Cohort Study: Diabetes Patients with NAFLD Have a Higher Risk of Cirrhosis and Hepatocellular Carcinoma
26 May, 2019 | 19:46h | UTCCommentaries: Diabetes patients at higher risk of deadly liver disease, finds study of 18 million people – Queen Mary University of London (free) AND Diabetes patients at high risk of serious NAFLD outcomes – Medwire News (free) AND Cirrhosis and liver cancer risk higher in people with type 2 diabetes – Medical News Today (free)
Recent Advances in the Management of Penile Cancer
26 May, 2019 | 12:32h | UTCRecent advances in the management of penile cancer – F1000Research (free)
[ASCO 2019] Study Finds Less Chemotherapy Noninferior to More in Frail and Elderly Patients With Advanced Gastroesophageal Cancer
25 May, 2019 | 18:53h | UTCAbstract: Optimizing chemotherapy for frail and elderly patients (pts) with advanced gastroesophageal cancer (aGOAC): The GO2 phase III trial. (free)
Canadian Recommendations for the Management of the Incidental Renal Mass in Adults
24 May, 2019 | 05:07h | UTCRecommendations for the Management of the Incidental Renal Mass in Adults: Endorsement and Adaptation of the 2017 ACR Incidental Findings Committee White Paper by the Canadian Association of Radiologists Incidental Findings Working Group – Canadian Association of Radiologists Journal (free)
Cohort Study: Breast Cancer Risk Increased in Transgender People Receiving Hormone Treatment
24 May, 2019 | 05:02h | UTCCommentaries: Breast cancer risk in transgender people: the value of gaining new insights from other sources – The BMJ Opinion (free) AND Risk of Breast Cancer Among Transgender People – The ASCO Post (free) AND Transgender women have increased risk of breast cancer compared to cisgender men – Cancer Research UK (free)
Review: FDG PET/CT for Assessing Tumor Response to Immunotherapy
21 May, 2019 | 18:50h | UTC
Google’s AI Improves Accuracy of Lung Cancer Diagnosis, Study Shows
21 May, 2019 | 06:10h | UTCGoogle’s AI improves accuracy of lung cancer diagnosis, study shows – STAT (free)
See also: A.I. Took a Test to Detect Lung Cancer. It Got an A. – The New York Times (10 articles per month are free)
Original Article: End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography – Nature Medicine (link to abstract – $ for full-text)
Final Overall Survival Analysis of the LATITUDE Trial in Newly Diagnosed, High-Risk, Metastatic, Castration-Sensitive Prostate Cancer
20 May, 2019 | 22:47h | UTCOriginal Article: Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial – The Lancet Oncology (link to abstract – 4 for full-text)
Management of Keratinocyte Carcinoma – Special Considerations in the Elderly
20 May, 2019 | 14:50h | UTC
Optimizing Cancer Pain Management in Resource-limited Settings
19 May, 2019 | 21:55h | UTCOptimizing cancer pain management in resource-limited settings – Supportive Care in Cancer (free)
Evaluation of the Solitary Pulmonary Nodule
19 May, 2019 | 21:47h | UTCEvaluation of the Solitary Pulmonary Nodule – Internal Medicine Journal (free)
Related: Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017 – Radiology (free) AND Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (free) AND British Thoracic Society guidelines for the investigation and management of pulmonary nodules (free) AND Management pathways for solitary pulmonary nodules – Journal of Thoracic Disease (free)
Current Status of MRI and PET in the NCCN Guidelines for Prostate Cancer
19 May, 2019 | 16:29h | UTC
NCCN Guideline: Prostate Cancer, Version 2.2019
19 May, 2019 | 16:23h | UTCRelated Guideline: NICE Guideline: Diagnosis and Management of Prostate Cancer (free)
Two Studies Point to Increase in Colorectal Cancer Incidence in Young Adults
19 May, 2019 | 13:27h | UTCChanges in colorectal cancer incidence in seven high-income countries: a population-based study – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Related Research: Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years – Gut (link to abstract – $ for full-text)
Commentaries: Bowel cancer rates rising ‘among young adults’ – BBC (free) AND Expert reaction to two studies on the rise of bowel cancer among young adults – Science Media Centre (free) AND Colorectal cancer is killing more 20- to 30-year-olds. We have some clues about why. – VOX (free)
Randomized Trial: Telephone-Based Rehab Program Helps People with Advanced Cancer Maintain Independence
19 May, 2019 | 12:50h | UTCOriginal Study: Effect of Collaborative Telerehabilitation on Functional Impairment and Pain Among Patients With Advanced-Stage Cancer: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Randomized Trial: Low-Fat Diet May Reduce the Risk of Death From Breast Cancer in Postmenopausal Women
17 May, 2019 | 06:57h | UTCSee also: Healthy diet cuts risk of dying from breast cancer in older women – Reuters (free) AND Less fat, more fruit may cut risk of dying of breast cancer – Associated Press (free) AND Balanced, Low-Fat Diet Reduces Risk of Death From Breast Cancer in Postmenopausal Women – ASCO News Releases (free)