Neurology
Quitting statins after stroke may raise risk of another stroke
3 Aug, 2017 | 19:43h | UTCCommentary: Quitting statins after stroke may raise risk of another stroke – AHA / ASA Newsroom (free) AND Many Stroke Patients Stop Statins or Never Start, With Dire Consequences – TCTMD (free) AND Stopping statins after stroke may increase second-stroke risk – Reuters (free)
Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest
1 Aug, 2017 | 17:38h | UTCTargeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Targeted Temperature Management for 24 vs. 48 Hours After OHCA – American College of Cardiology, Latest in Cardiology (free) AND Longer Induced Cooling Not Better After Cardiac Arrest – MedPage Today (free registration required)
“Small trial shows no advantage to an additional day of cooling” (from MedPage Today)
Diabetes mellitus and stroke: A clinical update
1 Aug, 2017 | 17:12h | UTCReview: Diabetes mellitus and stroke: A clinical update – World Journal of Diabetes (free)
Treatment Outcomes for Patients with Failed Back Surgery
1 Aug, 2017 | 17:09h | UTCSystematic Review: Treatment Outcomes for Patients with Failed Back Surgery – Pain Physician (free PDF)
Intensive speech therapy helps stroke survivors with persistent communication difficulties
28 Jul, 2017 | 22:14h | UTCIntensive speech therapy helps stroke survivors with persistent communication difficulties – NIHR Signal (free)
Original article: Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting – The Lancet (link to abstract – $ for full-text) AND commentary: Intensive speech therapy helps months after stroke – Reuters (free)
Surgical Informed Consent Process in Neurosurgery
28 Jul, 2017 | 15:37h | UTCReview: Surgical Informed Consent Process in Neurosurgery – Journal of Korean Neurosurgical society (free)
Social Interaction Improves Quality Of Life For People With Dementia
27 Jul, 2017 | 17:58h | UTCSocial Interaction Improves Quality Of Life For People With Dementia – NPR (free)
Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football
27 Jul, 2017 | 16:03h | UTCAuthor interview: Evaluation of Chronic Traumatic Encephalopathy in Football Players (free video)
Commentaries: High Prevalence of Evidence of CTE in Brains of Deceased Football Players – JAMA Network (free) AND Brain disease CTE seen in most football players in large report – STAT News (free) AND 110 N.F.L. Brains – The New York Times (10 articles per month are free) AND Signs of brain disease in 99 percent of ex-NFL players studied: paper – Reuters (free) AND Study: CTE Found In Nearly All Donated NFL Player Brains – NPR (free)
“A neuropathologist has examined the brains of 111 N.F.L. players — and 110 were found to have C.T.E., the degenerative disease linked to repeated blows to the head” (from NYT).
Early Orthostatic Hypotension and Orthostatic Intolerance
25 Jul, 2017 | 14:59h | UTCInvited commentary: Early Orthostatic Hypotension and Orthostatic Intolerance—More Than an Observation or Annoyance (free)
Practice Changing – Orthostatic hypotension within 1 min of standing (rather than at 3 minutes) has greater relation to falls, fracture, syncope, motor vehicle crash, and mortality.
Early vs Later Orthostatic Hypotension Assessment Times
25 Jul, 2017 | 20:53h | UTCInvited commentary: Early Orthostatic Hypotension and Orthostatic Intolerance—More Than an Observation or Annoyance (free)
Practice Changing – Orthostatic hypotension within 1 min of standing (rather than at 3 minutes) has greater relation to falls, fracture, syncope, motor vehicle crash, and mortality.
Parkinson Disease and Melanoma
25 Jul, 2017 | 00:51h | UTCParkinson Disease and Melanoma – Mayo Clinic Proceedings (free)
Commentary: Melanoma, Parkinson’s: See One, Be Aware of the Other – Medscape (free registration required)
Long-term morbidity and mortality in patients without early complications after stroke or transient ischemic attack
25 Jul, 2017 | 00:39h | UTCCommentaries: Stroke, TIA Survivors Without Early Complications Still Face Increased Long-Term Risks – Physician’s First Watch (free) AND Stroke survivors without early complications at long-term risk of death, stroke – Canadian Medical Association Journal, via EurekAlert (free)
Cardiocerebral and cardiopulmonary resuscitation – 2017 update
25 Jul, 2017 | 00:41h | UTCCardiocerebral and cardiopulmonary resuscitation – 2017 update – Acute Medicine & Surgery (free)
Source: Critical Care Reviews Newsletter
Is cyclobenzaprine useful for pain?
25 Jul, 2017 | 00:24h | UTCIs cyclobenzaprine useful for pain? – Therapeutics Initiative (free)
“…cyclobenzaprine is a long-acting sedative, not a muscle relaxant, and questioning whether any potential benefits are worth the side effects”. (from TI Newsletter). “If prescribed, a dose of 5 mg at bedtime should be tried first. Evidence suggests titration based on response and tolerability to a maximum dose of 15 mg/day, for no longer than one week”.
Amyloid PET for Mild Cognitive Impairment Diagnosis
25 Jul, 2017 | 00:14h | UTCAmyloid PET a ‘Game Changer’ for MCI Diagnosis – Medscape (free registration required)
Coverage from the Alzheimer’s Association International Conference (AAIC) 2017
Effectiveness of Lateral Decubitus Position for Preventing Post-Dural Puncture Headache
23 Jul, 2017 | 23:17h | UTCSource: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)
Evidence suggests lateral decubitus position is associated with reduced incidence of post-dural puncture headache.
Electrical stimulation can help people who are too weak to exercise
23 Jul, 2017 | 16:14h | UTCElectrical stimulation can help people who are too weak to exercise – The Conversation (free)
Cognitive Impairment and Heart Failure
23 Jul, 2017 | 16:04h | UTCCognitive Impairment and Heart Failure: Systematic Review and Meta-Analysis – Journal of Cardiac Failure (link to abstract – $ for full-text)
Commentary: Cognitive Impairment and HF – American College of Cardiology, Latest in Cardiology (free)
The Evolving Story of Overlapping Surgery
23 Jul, 2017 | 14:09h | UTCViewpoint: The Evolving Story of Overlapping Surgery – JAMA (free) (RT @pash22 see Tweet)
Commentary: 3 steps to restore patient trust in overlapping surgeries – FierceHealthcare (free)
This interesting viewpoint discusses the practice of scheduling overlapping surgeries, in which a qualified practitioner finishes noncritical parts of the first operation while the primary surgeon moves to the next surgery.
Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons
22 Jul, 2017 | 15:32h | UTCAssociation Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons – JAMA (link to abstract – $ for full-text)
Commentaries: Elevated Brain Amyloid Linked to Later Cognitive Decline – Medscape (free registration required) AND Amyloid Plaque and Cognitive Decline – Diagnostic Imaging (free) More Data Suggests Brain Amyloid Buildup Leads to Cognitive Decline – MedPage Today (free registration required) AND Elevated amyloid proves a warning sign of cognitive decline to come – Health Imaging (free) AND Study reveals early indication of Alzheimer’s in adults with normal cognition – News Medical (free)
More Millennials Are Having Strokes
22 Jul, 2017 | 14:54h | UTCPrevalence of Cardiovascular Risk Factors and Strokes in Younger Adults – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: More Millennials Are Having Strokes – Scientific American (free) AND Ischemic stroke hospitalizations among younger adults increased 30% or more in recent years – Cardiovascular Business (free) AND Higher incidence of stroke and greater prevalence of stroke risk factors in younger adults over the last decade – 2 Minute Medicine (free) Is Stroke Trending Younger? – MedPage Today (free registration required) AND More Data Suggest Stroke Rates Rising in Younger Adults – Medscape (free registration required)
Short review: Subarachnoid Hemorrhage
21 Jul, 2017 | 18:27h | UTCShort review: Subarachnoid Hemorrhage – NEJM Resident 360 (free)
Cerebellar Dysfunction in Multiple Sclerosis
21 Jul, 2017 | 18:13h | UTCReview: Cerebellar Dysfunction in Multiple Sclerosis – Frontiers in Neurology (free)
Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin
21 Jul, 2017 | 17:51h | UTCAntiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis – Stroke (link to abstract – $ for full-text)
Commentary: Adjusting Antiplatelet Regimen Could Decrease Risk For Stroke Patients on Aspirin Monotherapy – American College of Cardiology, Latest in Cardiology (free)
Meta-analysis of cohort studies: in patients who experienced an ischemic stroke or transient ischemic attack while on aspirin monotherapy, the addition of or a switch to another antiplatelet agent, versus aspirin monotherapy, was associated with a 32 percent reduction in the risk of major adverse cardiovascular events (HR 0.68; 0.54–0.85) and 30 percent reduction in recurrent strokes (HR, 0.70; 0.54–0.92). Additional randomized trials would better clarify the best antiplatet regimen for these patients.
NICE Guideline: Parkinson’s disease in adults
21 Jul, 2017 | 17:52h | UTCParkinson’s disease in adults – National Institute for Health and Care Excellence (NICE) Guideline (free)