Neurology
Guideline: Defining Optimal Brain Health in Adults
10 Sep, 2017 | 01:36h | UTCSee also: Advisory Highlights: Seven steps to keep your brain healthy from childhood to old age (free) AND News release: As brain problems increase, experts offer advice to keep yours healthy (free) AND Commentary: Optimal Cardiovascular Health and a Healthy Brain (free) AND Top Ten Things to Know: Defining Optimal Brain Health in Adults (free PDF)
Commentary: Heart and Stroke Groups Issue Advisory on Optimal Brain Health – Physician’s First Watch (free)
Study: Antipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities
10 Sep, 2017 | 01:31h | UTCAntipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities – The Canadian Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Antipsychotics common for adults with intellectual and developmental disabilities – Centre for Addiction and Mental Health (free) AND Antipsychotics Overused in Intellectually Disabled Adults – Medscape (free registration required)
“Antipsychotics are used inappropriately particularly in vulnerable groups: Poor children; Intellectually challenged; Autistic; Nursing homes. (RT @AllenFrancesMD see Tweet)
Study: Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease
9 Sep, 2017 | 23:16h | UTCPostoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary: Stereotactic Radiosurgery Achieves Better Quality of Life and Improved Cognition Than Whole-Brain Radiotherapy – ASCO Post (free)
Carers of stroke survivors voice an unmet need for practical and emotional support
9 Sep, 2017 | 21:33h | UTCCarers of stroke survivors voice an unmet need for practical and emotional support – NIHR Signal (free)
Original article: Carers’ Experiences, Needs, and Preferences During Inpatient Stroke Rehabilitation: A Systematic Review of Qualitative Studies – Archives of Physical Medicine and Rehabilitation (link to abstract – $ for full-text)
Meta-analysisis: vitamin D supplementation in chronic widespread pain
8 Sep, 2017 | 01:55h | UTCEffect of vitamin D supplementation in chronic widespread pain: a systematic review and meta-analysis – Clinical Rheumatology (link to abstract – $ for full-text)
Commentary: Vitamin D Supplementation Reduces Pain Scores in Chronic Widespread Pain – Practice Update (free registration required)
Guideline: diagnosis and treatment of cerebral venous thrombosis
7 Sep, 2017 | 20:17h | UTC
Meta-analysis: prediction of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs
7 Sep, 2017 | 21:02h | UTCIndividualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis – The Lancet Neurology (link to abstract – $ for full-text)
Commentary: Model Predicts Outcomes After AED Withdrawal – Neurology Reviews (free registration required)
Source: Journal Watch ($ resource to find articles of interest)
“A meta-analysis allows researchers to identify predictors of seizure recurrence and long-term seizure outcomes” (from Neurology Reviews).
Guideline: Management of Atherosclerotic Carotid and Vertebral Artery Disease
6 Sep, 2017 | 18:37h | UTCCommentary with highlights from the document: European Society for Vascular Surgery Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery Disease (free)
Systematic Reviews on Headache and migraine Prevention and Treatment
6 Sep, 2017 | 18:35h | UTCHeadache and migraine: interventions for preventing or treating headache and migraine – Cochrane Library (free) (RT @CochraneUK see Tweet)
Migraine awareness week (3-9 September). Latest Cochrane Evidence on interventions for preventing or treating headache and migraine.
Cohort Study: Physical Activity Frequency and the Risk of Stroke
6 Sep, 2017 | 18:32h | UTC“Even 1 to 2 times a week of moderate‐ to vigorous‐intensity physical activity might be beneficial to prevent a first‐ever stroke in the general population… from a public health perspective, we need to encourage inactive people to start exercising with more‐achievable goals”.
Guideline: Self‐Care for the Prevention and Management of Cardiovascular Disease and Stroke
4 Sep, 2017 | 15:30h | UTC
Study: Identifying incipient dementia individuals using machine learning and amyloid imaging
4 Sep, 2017 | 15:26h | UTCCommentaries: A.I., Big Data Project Predicts Dementia 2 Years Before Symptoms Onset, Researchers Show – Alzheimer’s News Today (free) AND Artificial intelligence predicts dementia before onset of symptoms – Science Daily (free)
See also related article and commentaries on Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons
Head injuries in sport must be taken more seriously
1 Sep, 2017 | 20:50h | UTCHead injuries in sport must be taken more seriously – Nature News (free)
“Sports organizations are only starting to understand the harm that can be inflicted by high-contact activities. Science must play its part in highlighting the problem and in aiding diagnosis”.
Review: Prevention of Alzheimer’s Disease
1 Sep, 2017 | 17:35h | UTCSource: PracticeUpdate
Meta-analysis: Association of Sleep-Disordered Breathing With Cognitive Function and Risk of Cognitive Impairment
30 Aug, 2017 | 20:37h | UTCAssociation of Sleep-Disordered Breathing With Cognitive Function and Risk of Cognitive Impairment: A Systematic Review Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: Breathing Disorders During Sleep Tied to Cognitive Issues – MedPage Today (free registration required) AND Sleep-Disordered Breathing Raises Risk for Cognitive Decline – Medscape (free registration required)
This meta-analysis of observational studies suggests a possible association. Further studies are needed to examine whether the treatment of this condition can help in the prevention of dementia and in improvement of cognition.
Study: Lack of REM sleep may lead to higher risk for dementia
30 Aug, 2017 | 19:08h | UTCSleep architecture and the risk of incident dementia in the community – Neurology (link to abstract – $ for full-text)
Commentaries: Lack of REM sleep may lead to higher risk for dementia – Boston University School of Medicine, via EurekAlert (free) AND Less REM Sleep May Significantly Boost Dementia Risk – Medscape (free registration required) AND Dreaming may keep dementia at bay – Medical News Today (free) AND Lack of REM sleep tied to increased risk of dementia – Reuters (free)
Study: Effectiveness of a Timing and Coordination Group Exercise Program to Improve Mobility in Older Adults
30 Aug, 2017 | 18:04h | UTCCommentary: On the Move exercise program improved mobility in older adults – 2 Minute Medicine (free)
#ESCCongress – Study: Closure of left atrial appendage during heart surgery protects the brain
29 Aug, 2017 | 15:09h | UTCClosure of left atrial appendage during heart surgery protects the brain (LAACS) – ESC Press Releases (free) (the results have not been published yet)
Commentary: LAACS: LAA Closure May Protect Against Long-Term Cerebral Ischemic Events – American College of Cardiology, Latest in Cardiology (free)
Meta-analysis: Effectiveness of Light Therapy in Cognitively Impaired Persons
29 Aug, 2017 | 14:52h | UTCEffectiveness of Light Therapy in Cognitively Impaired Persons: A Metaanalysis of Randomized Controlled Trials – Journal of The American Geriatric Society (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
Study: Is Parkinson’s Care Via Telemedicine as Effective as Going to the Clinic?
26 Aug, 2017 | 20:24h | UTCNational randomized controlled trial of virtual house calls for Parkinson disease – Neurology (link to abstract – $ for full-text)
Press release: Is Parkinson’s Care Via Telemedicine as Effective as Going to the Clinic? – American Academy of Neurology (free)
Commentaries: How Telemedicine Helps Those With Parkinson’s – Huffington Post (free) AND Telemedicine Equals Office Visits in Parkinson’s – MedPage Today (free registration required)
Viewpoint: Management of Parkinson Disease in 2017
26 Aug, 2017 | 20:17h | UTCViewpoint: Management of Parkinson Disease in 2017: Personalized Approaches for Patient-Specific Needs – JAMA (free)
Study: Is late-life dependency increasing or not?
26 Aug, 2017 | 17:03h | UTCCommentaries: The burden of triumph: meeting health and social care needs – The Lancet (free) AND Do we really need 200,000 more care home beds? – The Guardian (free) AND Time spent frail in old age ‘doubles’ – BBC (free)
“The amount of time spent needing daily care in late life has doubled in England over the past two decades, a study suggests”. (from BBC)
Study: Local Anesthetic With or Without Corticosteroid for Lumbar Spinal Stenosis
26 Aug, 2017 | 16:22h | UTCSource: ACP Journal Wise ($)
“Epidural injections of corticosteroid plus lidocaine offered no benefits from 6 weeks to 12 months beyond that of injections of lidocaine alone”
Systematic Review: First- and Second-Generation Antipsychotics in Children and Young Adults
26 Aug, 2017 | 16:04h | UTC
Systematic review: Interventions to Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia
26 Aug, 2017 | 16:07h | UTC


