Neurology
FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions
13 Jul, 2018 | 02:50h | UTCNews Release: FDA updates warnings for fluoroquinolone antibiotics on risks of mental health and low blood sugar adverse reactions – U.S. Food and Drug Administration (free)
Commentaries: FDA Strengthens Warnings for Fluoroquinolone Antibiotics – MPR (free) AND FDA Announces Labeling Changes for Fluoroquinolones Due to Mental Health AEs, Blood Sugar Disturbances – MD Magazine (free)
Amyotrophic Lateral Sclerosis: An Update for 2018
13 Jul, 2018 | 01:40h | UTCAmyotrophic Lateral Sclerosis: An Update for 2018 – Mayo Clinic Proceedings (free)
Refractory Status Epilepticus: Pearls and Pitfalls for the Resuscitation Room
13 Jul, 2018 | 01:39h | UTCRefractory Status Epilepticus: Pearls and Pitfalls for the Resuscitation Room – emDocs (free)
Review: ICU Delirium ― A Diagnostic and Therapeutic Challenge in the Intensive Care Unit
13 Jul, 2018 | 01:18h | UTCSource: Critical Care Reviews Newsletter
Randomized Trial: Antibiotic Prophylaxis for Patients with Neurogenic Bladder and Repeated Urinary Tract Infections
6 Jul, 2018 | 09:47h | UTCInvited Commentary: Preventing urinary tract infections in patients with neurogenic bladder (free)
Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain
6 Jul, 2018 | 09:37h | UTCCommentaries: Class of drugs used as alternative to opioids for back pain are ineffective, have potentially serious side effects: report – The Globe and Mail (free) AND Anticonvulsant drugs ineffective for low back pain and can cause harm, despite increased prescribing – CMAJ, via EurekAlert (free)
Related Meta-Analysis: Benefits and safety of gabapentinoids in chronic low back pain (free research and commentaries)
Cohort Study: Retinal Nerve Fiber Layer Thinning and Future Cognitive Decline
29 Jun, 2018 | 02:53h | UTCAssociation of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline: A Study Using Optical Coherence Tomography – JAMA Neurology (free for a limited period)
Commentaries: Eye Sign of Dementia Risk? Thinning of Retinal Nerve Fiber Layer – MedicalResearch.com (free) AND Are the Eyes Windows to Early Dementia? – MedPage Today (free registration required)
“A thinner Retinal Nerve Fiber Layer is associated with worse cognitive function in individuals without a neurodegenerative disease as well as greater likelihood of future cognitive decline”.
Case Series: Recurrent Glioblastoma Treated with Recombinant Poliovirus
29 Jun, 2018 | 02:50h | UTCRecurrent Glioblastoma Treated with Recombinant Poliovirus – New England Journal of Medicine (free for a limited period)
Editorial: Exploiting Viruses to Treat Diseases (free for a limited period)
Commentaries: Doctors Try Genetically Modified Poliovirus As Experimental Brain Cancer Treatment – NPR (free) AND Poliovirus therapy shows early promise in patients with aggressive brain cancer but questions linger – STAT (free)
Systematic Review: Donepezil for Dementia Due to Alzheimer’s Disease
29 Jun, 2018 | 02:36h | UTCDonepezil for dementia due to Alzheimer’s disease – Cochrane Library (free)
Summary: Donepezil for people with dementia due to Alzheimer’s disease – Cochrane Library (free)
Guideline: Advance Care Planning in Dementia
29 Jun, 2018 | 02:30h | UTCRelated: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries) AND Alzheimer’s? Your Paperwork May Not Be in Order – The New York Times (free)
Systematic Review: Non-pharmacological Interventions to Improve Nighttime Sleep Among Residents of Long-Term Care Settings
29 Jun, 2018 | 02:10h | UTC
Guideline: Management of Idiopathic Intracranial Hypertension
29 Jun, 2018 | 02:06h | UTC
NICE Guideline: Dementia
22 Jun, 2018 | 02:34h | UTC
Pharmacoepidemiological Study: Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms
22 Jun, 2018 | 02:28h | UTCAssociation of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study – Journal of Clinical Psychopharmacology (link to abstract – $ for full-text)
Commentaries: Incidence of Extrapyramidal Symptoms Higher With Certain Antidepressants – MPR (free) AND Antidepressants tied to Parkinson’s-like symptoms – Univadis (free registration required)
“Observational study: Incidence of EPSs with antidepressants. RRs: duloxetine, 5.68; mirtazapine, 3.78; citalopram, 3.47; escitalopram, 3.23; paroxetine, 3.07; sertraline, 2.57; venlafaxine, 2.37; bupropion, 2.31; and fluoxetine, 2.03 (all significant)” (via @psychopharmacol see Tweet)
Perspective: Sleep Disorders Associated With Alzheimer’s Disease
22 Jun, 2018 | 02:17h | UTCSleep Disorders Associated With Alzheimer’s Disease: A Perspective – Frontiers in Neuroscience (free)
Position Paper: Treatment of Nightmare Disorder in Adults
18 Jun, 2018 | 23:01h | UTCCommentary: New position paper recommends treatment options for nightmare disorder in adults – American Academy of Sleep Medicine, via EurekAlert (free)
Report: Current Endovascular Strategies for Cerebral Venous Thrombosis
18 Jun, 2018 | 09:15h | UTC
Guideline: Efficacy and Tolerability of the New Antiepileptic Drugs
18 Jun, 2018 | 00:21h | UTCPractice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs – American Academy of Neurology and the American Epilepsy Society
Part I: Treatment of new-onset epilepsy (free PDF)
Part II: Treatment-resistant epilepsy (free PDF)
Commentary: New Epilepsy Guidelines Shed Light on Explosion of New Drugs – MedPage Today (free registration required)
Cohort Study: High Blood Pressure in 50-year-olds Associated with Higher Risk of Dementia
15 Jun, 2018 | 02:13h | UTCCommentaries: Dementia risk increased in 50-year-olds with blood pressure below hypertension threshold – European Society of Cardiology, via EurekAlert (free) AND Blood pressure below treatable threshold linked to heightened dementia risk – OnMedica (free) AND Studies: Higher blood pressure increases risk for dementia – UPI (free) AND High Blood Pressure at Age 50 Tied to Dementia Risk – The New York Times (10 articles per month are free) AND Dementia risk to 50-year-olds with raised blood pressure – study – The Guardian (free)
Review: Antiepileptic Drugs in Critically Ill Patients
15 Jun, 2018 | 02:05h | UTCAntiepileptic drugs in critically ill patients – Critical Care (free)
Randomized Trial: Antipsychotic Treatment of Very Late-onset Schizophrenia-like Psychosis
15 Jun, 2018 | 00:55h | UTCCommentaries: Very late-onset schizophrenia-like psychosis: positive findings but questions remain unanswered – The Lancet Psychiatry (free) AND Low-Dose Antipsychotic Effective in Late-Onset Psychosis – Medscape (free registration required) AND Low-dose amisulpride effective for late-onset psychosis – Healio (free registration required)
Randomized Trial Continuous Low-dose Antibiotic Prophylaxis to Prevent UTI in Adults who Perform Clean Intermittent Self-catheterization
7 Jun, 2018 | 02:52h | UTC“The results of this large randomised trial, conducted in accordance with best practice, demonstrate clear benefit for antibiotic prophylaxis in terms of reducing the frequency of UTI for people carrying out CISC”.
Systematic Review: Exercise for Cognitive Brain Health in Aging
7 Jun, 2018 | 02:43h | UTCExercise for cognitive brain health in aging: A systematic review for an evaluation of dose – Neurology Clinical Practice (link to abstract – $ for full-text)
Commentary: How Much Exercise Is Needed to Help Improve Thinking Skills? – American Academy of Neurology, via NewsWise (free) AND Exercise regimen can maintain cognition in older adults, researchers say – UPI (free) AND 1-Hour Exercise, 3 Times a Week Boosts Cognition in Older Adults – MedPage Today (free registration required)
Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders
7 Jun, 2018 | 02:37h | UTCCurrent Concepts in Diagnosis and Treatment of Functional Neurological Disorders – JAMA Neurology (free for a limited period)
Review: Perimesencephalic Hemorrhage
6 Jun, 2018 | 21:35h | UTCPerimesencephalic Hemorrhage: A Review of Epidemiology, Risk Factors, Presumed Cause, Clinical Course, and Outcome – Stroke (free for a limited period)