Neurology | Page 42 of 81 | Links Medicus Content Curation & Alerts in Medicine

DEVT, SKIP Trials Add Support for Omitting IV tPA Before Stroke Thrombectomy

27 Jan, 2021 | 01:01h | UTC

DEVT, SKIP Trials Add Support for Omitting IV tPA Before Stroke Thrombectomy – TCTMD

Original studies and commentaries: Randomized trial: Endovascular treatment alone noninferior to intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke

American Clinical Neurophysiology Society’s Standardized Critical Care EEG Terminology: 2021 Version

25 Jan, 2021 | 01:15h | UTC

American Clinical Neurophysiology Society’s Standardized Critical Care EEG Terminology: 2021 Version – Journal of Clinical Neurophysiology

Cohort study: Long-term clinical outcomes of hematopoietic stem cell transplantation in 210 patients with multiple sclerosis

25 Jan, 2021 | 01:15h | UTC

Long-Term Clinical Outcomes of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis – Neurology (link to abstract – $ for full-text)

Meta-analysis: Clinical presentation, investigation findings, and treatment outcomes of spontaneous intracranial hypotension syndrome

22 Jan, 2021 | 08:12h | UTC

Clinical Presentation, Investigation Findings, and Treatment Outcomes of Spontaneous Intracranial Hypotension Syndrome: A Systematic Review and Meta-analysis – JAMA Neurology

Commentary on Twitter

This meta-analysis offers a comprehensive and objective summary of the evidence on SIH. Spontaneous intracranial hypotension should not be excluded on the basis of a non-orthostatic headache, normal neuroimaging or normal lumbar puncture opening pressure https://t.co/BcVk2ftcs3

— JAMA Neurology (@JAMANeuro) January 4, 2021

Meta-analysis: Prevalence of postural hypotension in primary, community and institutional care

22 Jan, 2021 | 08:09h | UTC

Prevalence of postural hypotension in primary, community and institutional care: a systematic review and meta-analysis – BMC Family Medicine

Randomized trial: Oral Rimegepant for preventive treatment of migraine

21 Jan, 2021 | 01:04h | UTC

Oral rimegepant for preventive treatment of migraine: a phase 2/3, randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Rimegepant bests placebo for preventing migraine – MedicalXpress

Against placebo? It would be interesting to know how this new drug works against other established treatments.

Randomized trial: In pediatric acute CNS infections, 3% Hypertonic saline is superior to 20% Mannitol for reducing intracranial pressure

21 Jan, 2021 | 01:08h | UTC

Randomized Clinical Trial of 20% Mannitol Versus 3% Hypertonic Saline in Children With Raised Intracranial Pressure Due to Acute CNS Infections – Pediatric Critical Care Medicine (link to abstract – $ for full-text)

Commentary on Twitter

Feature w/#VisualAbstract

RCT of 20% mannitol vs. 3% hypertonic saline in children w/raised ICP due to acute CNS infections: Which is superior?

Rameshkumar, @drarunbansal, Jayashree 🇮🇳: https://t.co/ZGWaPMhPvr

Editorial by Argent 🇿🇦: https://t.co/BsbZKsEG03 #PedsICU @WFPICCS pic.twitter.com/5asM9HNQaN

— Pediatric Critical Care Medicine (@PedCritCareMed) December 21, 2020

Acute flaccid myelitis: Cause, diagnosis, and management

21 Jan, 2021 | 00:58h | UTC

Acute flaccid myelitis: cause, diagnosis, and management – The Lancet (free registration required)

Case series: Portable Magnetic Resonance Imaging for ICU Patients

21 Jan, 2021 | 00:54h | UTC

Portable Magnetic Resonance Imaging for ICU Patients – Critical Explorations

Consensus statement: Electrodiagnostic assessment of the autonomic nervous system

21 Jan, 2021 | 00:34h | UTC

Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology – Clinical Neurophysiology

Randomized trial: Endovascular treatment alone noninferior to intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke

20 Jan, 2021 | 01:35h | UTC

Effect of Endovascular Treatment Alone vs Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients With Acute Ischemic Stroke: The DEVT Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke – JAMA (free for a limited period)

Video: Thrombolysis Before Thrombectomy for Stroke

Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease

20 Jan, 2021 | 01:20h | UTC

Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease – New England Journal of Medicine

Commentary: Parkinson’s Motor Symptoms Improve with Focused Ultrasound — Adverse events were frequent, with some persisting 4 months or longer

Study: Seizure frequency does not increase during Pregnancy

15 Jan, 2021 | 08:28h | UTC

Changes in Seizure Frequency and Antiepileptic Therapy during Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: MONEAD Study: Does Pregnancy Lead to Increased Seizure Frequency in Women with Epilepsy? – Physician’s Weekly AND Pregnancy Does Not Increase Seizures in Women With Epilepsy – Medscape

Systematic review: Acute treatments for episodic migraine

13 Jan, 2021 | 01:56h | UTC

Acute Treatments for Episodic Migraine – Agency for Healthcare Research and Quality

Full text: Acute Treatments for Episodic Migraine

Evidence summary: Acute Treatments for Episodic Migraine

Systematic review: There is no evidence that Souvenaid is useful for preventing dementia or provide benefit for patients with Alzheimer’s disease

13 Jan, 2021 | 01:47h | UTC

Souvenaid for Alzheimer’s disease – Cochrane Library

AASM Guideline: Behavioral and psychological treatments for chronic insomnia disorder in adults

13 Jan, 2021 | 01:58h | UTC

Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline – Journal of Clinical Sleep Medicine

Commentary: New guideline encourages use of cognitive behavioral therapy for insomnia in adults – ACP Internist

Cohort study: Prevalence and risk factors for delirium in critically ill patients with COVID-19

12 Jan, 2021 | 01:55h | UTC

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study – The Lancet Respiratory Medicine

Commentaries: Sedation in mechanically ventilated patients with COVID-19 – The Lancet Respiratory Medicine AND Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients – Vanderbilt University Medical Center

Randomized trial: Ultra-early tranexamic acid does not improve outcomes after subarachnoid hemorrhage

10 Jan, 2021 | 21:02h | UTC

Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Tranexamic acid treatment in spontaneous subarachnoid haemorrhage, started immediately after CT diagnosis and continued until start of the aneurysm treatment as early as possible, does not improve clinical outcome, finds new randomised controlled trial: https://t.co/R0AhtszaY5 pic.twitter.com/Bnft9XgBA9

— The Lancet (@TheLancet) December 22, 2020

Guideline Synopsis: Management of patients with a patent foramen ovale with history of stroke or TIA

10 Jan, 2021 | 20:19h | UTC

Management of Patients With a Patent Foramen Ovale With History of Stroke or TIA – JAMA (free for a limited period)

Original Guideline: Practice advisory update summary: Patent foramen ovale and secondary stroke prevention: Report of the Guideline Subcommittee of the American Academy of Neurology – Neurology

Meta-analysis: Effectiveness of bundle interventions on ICU delirium

10 Jan, 2021 | 20:16h | UTC

Effectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine

Commentary: ICU bundles do not appear to improve delirium but may help other outcomes – ACP Hospitalist

Commentary on Twitter

Meta-Analysis incl 11 studies and 26,384 patients for bundle-interventions of delirium treatment showed no effects on delirum duration ( –1.42 d; 95% CI –3.06 to 0.22) or prevalence (risk ratio = 0.92; 95% CI, 0.68–1.24)https://t.co/PzZBGttOL8

— Peter Nydahl (@NydahlPeter) December 18, 2020

Neuroimaging manifestations in children with SARS-CoV-2 infection: a multinational, multicenter collaborative study

18 Dec, 2020 | 09:50h | UTC

Neuroimaging manifestations in children with SARS-CoV-2 infection: a multinational, multicentre collaborative study – The Lancet Child & Adolescent Health

Commentary: Study highlights neurological impact of COVID-19 on children – University of Manchester

Commentary on Twitter (thread – click for more)

New #COVID19 Research: An international call for cases identified 38 children with neurological disease related to #SARSCoV2 infection

Recurring patterns of disease were identified, with #neuroimaging abnormalities ranging from mild to severehttps://t.co/a3bjPlOY0z pic.twitter.com/W0lxLP4aAh

— The Lancet Child & Adolescent Health (@LancetChildAdol) December 16, 2020

Randomized trial: Dexamethasone for chronic subdural hematoma resulted in fewer favorable outcomes and more adverse events than placebo at 6 months

17 Dec, 2020 | 09:02h | UTC

Trial of Dexamethasone for Chronic Subdural Hematoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Dexamethasone should be avoided in patients with chronic subdural haematoma – University of Cambridge AND Dexamethasone for Chronic Subdural Hematoma? – NEJM Journal Watch

Commentary on Twitter

In a trial that compared a 2-week course of dexamethasone with placebo in patients with a chronic subdural hematoma, a favorable outcome on the modified Rankin scale at 6 months was more common in the placebo group than in the dexamethasone group.

— NEJM (@NEJM) December 17, 2020