Neurology
RCT: Baclofen reduces agitation in patients with unhealthy alcohol use receiving mechanical ventilation, but results in a longer time receiving mechanical ventilation and more extended ICU stay
28 Feb, 2021 | 21:09h | UTCEditorial: Baclofen to Prevent Agitation Caused by Alcohol Withdrawal in the ICU
Video presentation: Effect of Baclofen on Agitation-Related Events Among Mechanically Ventilated Patients With Alcohol Use Disorder
Commentary on Twitter
In this phase 3 RCT, high-dose baclofen reduced agitation-related events vs placebo in patients with unhealthy alcohol use receiving mechanical ventilation; considering the modest effect & secondary endpoints & adverse events, further research is needed https://t.co/gHWEqZKfFv
— JAMA (@JAMA_current) February 23, 2021
RCT: An intensive blood pressure lowering strategy after successful endovascular therapy in acute ischemic stroke did not reduce radiographic intraparenchymal hemorrhage rates
28 Feb, 2021 | 20:59h | UTCSafety and efficacy of intensive blood pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
Systematic Review: Cardiovascular Effects of Medical Marijuana
28 Feb, 2021 | 20:48h | UTCCardiovascular Effects of Medical Marijuana: A Systematic Review – The American Journal of Medicine
Systematic Review: Insufficient evidence to decide whether surgical intervention is beneficial or harmful for the early management of Bell’s palsy
26 Feb, 2021 | 08:20h | UTCSurgical interventions for the early management of Bell’s palsy – Cochrane Library
Summary: Surgical operation for Bell’s palsy (idiopathic facial paralysis) – Cochrane Library
RCT: Dimenhydrinate and metoclopramide equally effective in the treatment of nausea due to vertigo
26 Feb, 2021 | 08:12h | UTCComparison of efficacy dimenhydrinate and metoclopramide in the treatment of nausea due to vertigo; a randomized study – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
Review: Diagnosis and Treatment of Multiple Sclerosis
24 Feb, 2021 | 02:23h | UTCDiagnosis and Treatment of Multiple Sclerosis: A Review – JAMA
Podcast: Diagnosis and Treatment of Multiple Sclerosis—A Review
M-A: The diagnostic accuracy of noninvasive methods to measure the intracranial pressure
23 Feb, 2021 | 01:14h | UTC
Ocular MRI findings in patients with severe COVID-19
17 Feb, 2021 | 01:42h | UTCCommentaries: New COVID-19 side effect: MRI links severe infection to dangerous eye problems – Health Imaging AND MRI illuminates COVID-19’s negative impact on the eyes – AuntMinnie AND Windows of Infection: MRI Reveals COVID-19-Linked Eye Abnormalities – Diagnostic Imaging
Effectiveness of telerehabilitation in physical therapy: A rapid overview
16 Feb, 2021 | 01:53h | UTCEffectiveness of telerehabilitation in physical therapy: A rapid overview – Physical Therapy
How effective is magnesium in for the treatment of migraine?
16 Feb, 2021 | 01:48h | UTCHow Effective is Magnesium in your MAGraine Cocktail? – Journal Feed
Original study: MAGraine: Magnesium compared to conventional therapy for treatment of migraines – American Journal of Emergency Medicine
[Preprint] Six-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19
12 Feb, 2021 | 02:14h | UTCSix-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19 – medRxiv
Commentary: Covid linked to risk of mental illness and brain disorder, study suggests – The Guardian
SR: Plasma and cerebrospinal fluid ABeta42 for the differential diagnosis of Alzheimer’s disease dementia
12 Feb, 2021 | 01:53h | UTC
RCT: In patients with generalized myasthenia gravis prescribed azithromycin, rapid tapering of prednisone is beneficial and safe compared to slow tapering
10 Feb, 2021 | 01:32h | UTC
Commentary on Twitter
Rapid tapering of high-dose #prednisone therapy in patients with moderate to severe generalized #myastheniagravis on azathioprine appears to be well tolerated and associated with good outcome https://t.co/1nHZuy8kPN
— JAMA Neurology (@JAMANeuro) February 8, 2021
Canadians Win Again – Syncope Score Systematic Review
9 Feb, 2021 | 01:03h | UTCCanadians Win Again – Syncope Score Systematic Review – Journal Feed
See calculator: Canadian Syncope Risk Score – MdCalc
Prospective validation of Canadian TIA Score for subsequent stroke risk after transient ischemic attack
7 Feb, 2021 | 20:54h | UTCSee calculator: Canadian TIA Score
Commentary on Twitter
Jeff Perry is at it again! The ABCD2 score lacks the ability to discriminate low and high risk patients following TIA, so Perry et al. have validated the Canadian TIA Score.
Infographic and bedside calculator: https://t.co/OcbaK1aG3t
Full publication: https://t.co/wt87PKzNkO pic.twitter.com/q3QdgVxp6x
— EM Ottawa (@emergmedottawa) February 4, 2021
Review: Dysphagia in older adults
5 Feb, 2021 | 01:22h | UTCDysphagia in Older Adults – Mayo Clinic Proceedings
USPSTF recommends against screening for asymptomatic carotid artery stenosis in the general adult population
3 Feb, 2021 | 01:29h | UTCEditorials: Screening for Asymptomatic Carotid Artery Stenosis: Lack of Clinical Benefit, Potential for Harm – JAMA AND Screening for Asymptomatic Carotid Artery Stenosis in Adult Patients: Unclear Benefit but Downstream Risks – JAMA Internal Medicine AND USPSTF Recommendations for Screening for Carotid Stenosis to Prevent Stroke—The Need for More Data – JAMA Network Open
Author interview: USPSTF Recommendation: Carotid Artery Stenosis
JAMA Patient Page: Screening for Carotid Artery Stenosis
Living systematic review on Cannabis and other plant-based treatments for chronic pain
2 Feb, 2021 | 01:01h | UTC
Meta-analysis of longitudinal studies: Frequent or dependent cannabis use in youth linked to decline IQ
2 Feb, 2021 | 01:02h | UTC
fMRI identifies smell and taste malfunction in COVID-19 patients
2 Feb, 2021 | 01:16h | UTCfMRI Identifies Smell and Taste Malfunction in COVID-19 Patients – Clinical Imaging
Commentary on Twitter
Absent BOLD fMRI Activation of Orbitofrontal Cortex in a Patient With Persistent Cacosmia and Cacogeusia After COVID-19 https://t.co/bAa7sf6wNR
— Nat Rev Neurology (@NatRevNeurol) January 25, 2021
Association of dilated perivascular spaces with cognitive decline and incident dementia
1 Feb, 2021 | 01:38h | UTCThe Association of Dilated Perivascular Spaces with Cognitive Decline and Incident Dementia – Neurology (link to abstract – $ for full-text)
Commentaries: Large, Fluid-Filled Spaces Seen on Brain MRI Could Indicate Future Dementia – Diagnostic Imaging AND Perivascular Space Pathology Linked to Dementia in Seniors – HealthDay
Commentary on Twitter
.@GreenJournal: Severe perivascular space pathology in both centrum semiovale and basal ganglia was correlated with a greater risk of #dementia and #cognitive decline, regardless of other small vessel disease markers. #neurology @UNSW https://t.co/pHUhNBGpYw pic.twitter.com/dfaVvrTObx
— Neurology Today (@NeurologyToday) January 28, 2021
Blood test to detect psychogenic nonepileptic seizures shows promise
1 Feb, 2021 | 01:37h | UTCBlood Test to Detect Psychogenic Nonepileptic Seizures Shows Promise – Physician’s Weekly
Original study: Association of Epileptic and Non-epileptic Seizures and Changes in Circulating Plasma Proteins Linked to Neuroinflammation – Neurology (link to abstract – $ for full-text)
Systematic review: Worldwide incidence and prevalence of Neuromyelitis Optica
29 Jan, 2021 | 01:31h | UTCWorldwide Incidence and Prevalence of Neuromyelitis Optica: A Systematic Review – Neurology
Cohort study: Incidence of transient ischemic attack and association with long-term risk of stroke
28 Jan, 2021 | 01:28h | UTCIncidence of Transient Ischemic Attack and Association With Long-term Risk of Stroke – JAMA (free for a limited period)
Commentary: New study provides both good and bad news about transient ischemic attacks – News Medical
Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association
28 Jan, 2021 | 01:23h | UTC