Neurology
Antiepileptic drug monotherapy for epilepsy: a network meta‐analysis of individual participant data.
8 Apr, 2022 | 10:20h | UTCSummary: Antiepileptic drug monotherapy (single drug treatment) for epilepsy – Cochrane Library
Stroke: advances in treatment offer hope for patients.
8 Apr, 2022 | 10:23h | UTCStroke: advances in treatment offer hope for patients – Evidently Cochrane
M-A: Mechanical thrombectomy with retrievable stents and aspiration catheters for acute ischemic stroke.
8 Apr, 2022 | 10:21h | UTCMechanical thrombectomy with retrievable stents and aspiration catheters for acute ischaemic stroke: a meta-analysis of randomised controlled trials – EuroIntervention (link to abstract – $ for full-text)
Commentary: Mechanical Stroke Thrombectomy May Reduce Death: Meta-analysis – TCTMD
Commentary on Twitter
Contemporary trials of mechanical #thrombectomy for acute ischaemic stroke confirmed a reduction in disability with a large effect size. The pooled available evidence also supported a significant reduction in all-cause mortality at 3 months. #EAPCI https://t.co/330nKIP1zP pic.twitter.com/9vLMZtOskS
— EuroIntervention (@EuroInterventio) April 4, 2022
RCT: Effect of different corticosteroid dosing regimens on clinical outcomes in boys with Duchenne Muscular Dystrophy.
7 Apr, 2022 | 08:53h | UTCEffect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial – JAMA (free for a limited period)
Related:
RCT: Routine lung volume recruitment is not beneficial for boys with Duchenne muscular dystrophy.
Research: Long-term effects of glucocorticoids in patients with Duchenne muscular dystrophy
Commentary on Twitter
In this randomized clinical trial of boys with Duchenne muscular dystrophy, treatment with daily #prednisone or daily #deflazacort resulted in significantly better outcomes compared with intermittent prednisone. https://t.co/rKjSrjVemR #AAN2022 pic.twitter.com/qPNV9KBOXv
— JAMA (@JAMA_current) April 5, 2022
RCT: In patients undergoing intraarterial treatment for stroke, functional outcomes after 3 months were similar with general anesthesia vs. sedation.
7 Apr, 2022 | 08:00h | UTC
Commentary on Twitter
Previous speculations have considered the relationship between anesthetic strategy and patient outcomes. Now, new research suggests general #anesthesia and #sedation produce comparable outcomes after endovascular treatment for stroke. https://t.co/ggLRO8Or3W pic.twitter.com/dLLGA4Vmgk
— Anesthesiology (@_Anesthesiology) March 24, 2022
Systematic Review: Brivaracetam add‐on therapy for drug‐resistant epilepsy.
7 Apr, 2022 | 07:50h | UTCBrivaracetam add‐on therapy for drug‐resistant epilepsy – Cochrane Library
Summary: Brivaracetam add-on therapy for drug-resistant epilepsy – Cochrane Library
RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.
6 Apr, 2022 | 10:47h | UTC
Review: Antiseizure medications for adults with epilepsy.
6 Apr, 2022 | 10:25h | UTCAntiseizure Medications for Adults With Epilepsy: A Review – JAMA (free for a limited period)
Audio Clinical Review: Epilepsy Diagnosis and Treatment in Adults – JAMA
Craniocervical artery dissections: a concise review for clinicians.
6 Apr, 2022 | 10:06h | UTCCraniocervical Artery Dissections: A Concise Review for Clinicians – Mayo Clinic Proceedings
Opinion | Medicinal cannabis for chronic pain: the Bermuda triangle of low-quality studies, countless meta-analyses and conflicting recommendations.
5 Apr, 2022 | 08:52h | UTCRelated:
M-A: Birth outcomes of neonates exposed to marijuana in utero.
Cannabis-related allergies: an international overview and consensus recommendations.
Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.
Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
Guideline: Medical cannabis or cannabinoids for chronic pain.
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
Review: Considerations for cannabinoids in perioperative care by anesthesiologists.
Review: Cannabis-based Medicines and the Perioperative Physician
Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know
Cohort Study: Change in heart disease and stroke mortality before and during the Covid-19 pandemic.
5 Apr, 2022 | 08:47h | UTCCommentaries:
Several-Fold Increase in Stroke and Heart Disease Deaths During COVID-19 Pandemic – NeurologyToday
2019 to 2020 Saw Risk-Linked Deaths From Heart Disease, Stroke Up – HealthDay
Commentary from the author on Twitter (thread – click for more). Article and images under CC-BY License
Our paper @JAMANetworkOpen Sidney et al. https://t.co/bfCX9akd6p 2019 – 2020, several-fold ⬆️ in risk-associated deaths from Heart Disease & Stroke, with greater ⬆️ minorities & highest ⬆️among Black adults. More evidence of underlying systemic inequities & structural racism 🧵 pic.twitter.com/goQgPmRU9c
— Jamal Rana, MD (@JamalRanaMD) March 23, 2022
M-A: Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain.
5 Apr, 2022 | 08:29h | UTC
RCT: Routine lung volume recruitment is not beneficial for boys with Duchenne muscular dystrophy.
5 Apr, 2022 | 08:04h | UTC
Systematic Review: Occupational therapy for cognitive impairment in stroke patients.
4 Apr, 2022 | 00:25h | UTCOccupational therapy for cognitive impairment in stroke patients – Cochrane Library
Summary: Occupational therapy for cognitive impairment in people who have had a stroke – Cochrane Library
RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults.
1 Apr, 2022 | 10:07h | UTCCommentaries:
Study raises questions about risks of using medical marijuana for mood and anxiety disorders – CNN
Medical Marijuana Rx Ups Odds for Overuse, With No Benefit to Health: Study – HealthDay
Commentary on Twitter
RCT finds medical marijuana cards (MMC) are linked to an increase in cannabis use disorder, with no improvements in pain, depression, and anxiety for adults using medical marijuana but improvements in sleep. https://t.co/0gtGFi1RQ9
— JAMA Network Open (@JAMANetworkOpen) March 18, 2022
State of the Art Review: The heart brain team and patient-centered management of ischemic stroke.
1 Apr, 2022 | 09:53h | UTCThe Heart Brain Team and Patient-Centered Management of Ischemic Stroke – JACC: Advances
Study finds no increased risk of brain tumors for mobile phone users.
1 Apr, 2022 | 10:04h | UTCNews Release: No increased risk of brain tumours for mobile phone users, new study finds – University of Oxford
Original Study: Cellular Telephone Use and the Risk of Brain Tumors: Update of the UK Million Women Study – JNCI: Journal of the National Cancer Institute
Guideline for the management of neurogenic bowel dysfunction in spinal cord injury/disease.
1 Apr, 2022 | 08:50h | UTCGuideline for the management of neurogenic bowel dysfunction in spinal cord injury/disease – Spinal Cord (if the link is paywalled, try this one)
M-A: Psychological interventions for chronic, non-specific low back pain.
31 Mar, 2022 | 08:20h | UTCNews Release: Study sheds light on psychological therapies for chronic low back pain – British Medical Journal
AHA/ASA Scientific Statement: Endovascular treatment and thrombolysis for acute ischemic stroke in patients with premorbid disability or dementia.
30 Mar, 2022 | 10:33h | UTCNews Release: Stroke treatments safe and effective for people with existing disability or dementia – American Heart Association
Commentary on Twitter (thread – click for more)
1/ Endovascular Treatment and Thrombolysis for Acute Ischemic Stroke in Patients with Pre-morbid Disability or Dementia
Authors: @draravindganesh @pecouille @SMGreenbergNeur @Doctorjfred @mayank_G0 @NAsdaghi @GPerue
Published today in @StrokeAHA_ASA: https://t.co/9VdIvGDNoN pic.twitter.com/CgET4ygCHu
— AHA Science (@AHAScience) March 28, 2022
Systematic Review: Pregabalin add‐on for drug‐resistant focal epilepsy.
30 Mar, 2022 | 10:10h | UTCPregabalin add‐on for drug‐resistant focal epilepsy – Cochrane Library
Summary: Pregabalin add-on for drug-resistant focal epilepsy – Cochrane Library
Review: Diagnosis and neurointerventional management of large vessel occlusion acute ischemic stroke.
29 Mar, 2022 | 08:39h | UTC
European clinical guidelines for Tourette syndrome and other tic disorders.
29 Mar, 2022 | 08:26h | UTCPart I: assessment
Part II: psychological interventions
Part III: pharmacological treatment
Part IV: deep brain stimulation
Related: Guideline: Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders
Guidelines for Parkinson’s disease treatment.
28 Mar, 2022 | 09:43h | UTC
Study Commentary: Symptoms can appear up to 10 years before a Parkinson’s disease diagnosis in a primary care setting.
28 Mar, 2022 | 08:37h | UTCOriginal Study: Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population – JAMA Neurology (link to abstract – $ for full-text)