Neurology
RCT: A single immediate dose of intravenous tenecteplase is noninferior to alteplase for the treatment of patients with acute ischemic stroke.
1 Jul, 2022 | 11:44h | UTCIntravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
News Release: UCalgary researchers with the Calgary Stroke Program make another breakthrough in the treatment of stroke
Cohort Study: Association of posttraumatic stress disorder with accelerated cognitive decline in middle-aged women.
1 Jul, 2022 | 11:21h | UTC
Commentary on Twitter
This cohort study found trauma-exposed middle-aged women with high levels of PTSD symptoms experienced worse cognitive decline compared to those with no PTSD symptoms. https://t.co/sV88HNy1JJ
— JAMA Network Open (@JAMANetworkOpen) June 30, 2022
Cohort Study: Association of time elapsed since ischemic stroke with risk of recurrent stroke in older patients undergoing elective nonneurologic, noncardiac surgery.
30 Jun, 2022 | 11:16h | UTCAssociation of Time Elapsed Since Ischemic Stroke With Risk of Recurrent Stroke in Older Patients Undergoing Elective Nonneurologic, Noncardiac Surgery – JAMA Surgery (free for a limited period)
Invited Commentary: Perioperative Stroke Risk Model—One Size Fits All? – JAMA Surgery
M-A: The association between vision impairment and cognitive outcomes in older adults.
30 Jun, 2022 | 10:26h | UTCNews Release: New study indicates sight problems may increase dementia risk in older adults – Taylor & Francis
Review: Common hand conditions.
29 Jun, 2022 | 11:57h | UTCCommon Hand Conditions: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis and Treatment of Common Hand Conditions
RCT: Cognitive behavioral therapy for veterans with comorbid posttraumatic headache and posttraumatic stress disorder symptoms.
29 Jun, 2022 | 11:21h | UTC
Commentary on Twitter
Outcomes from our @strongstar_ptsd trial of nonpharmacological treatment for posttraumatic headache was published in @JAMANeuro today! This study found strong efficacy for a CBT intervention for posttraumatic headache and, surprisingly, comorbid PTSD.https://t.co/KZWofaBB6c
— Don McGeary, PhD (@DonMcgeary) June 27, 2022
Epilepsy: what are the best medications?
28 Jun, 2022 | 11:14h | UTCEpilepsy: what are the best medications? – Evidently Cochrane
Original Study: Antiepileptic drug monotherapy for epilepsy: a network meta‐analysis of individual participant data – Cochrane Library
Systematic Review: Routine or selective carotid artery shunting for carotid endarterectomy (and different methods of monitoring in selective shunting).
28 Jun, 2022 | 10:53h | UTC
M-A: Clinical presentation and outcomes of Acute Disseminated Encephalomyelitis (ADEM) in adults worldwide.
28 Jun, 2022 | 10:47h | UTC
RCT: Evaluation of an online intervention for improving stroke survivors’ health-related quality of life.
28 Jun, 2022 | 10:44h | UTC
Infertility, recurrent pregnancy loss, and risk of stroke: pooled analysis of individual patient data of 618 851 women.
27 Jun, 2022 | 11:59h | UTCNews Release: Infertility and pregnancy loss may increase women’s risk of stroke – BMJ Newsroom
Commentary on Twitter
Infertility and pregnancy loss are associated with an increased risk of non-fatal and fatal stroke in later life, finds study.
Early monitoring of women who have experienced miscarriage or stillbirth could lower the risk, the researchers suggest https://t.co/fYrNfpz6fC
— The BMJ (@bmj_latest) June 24, 2022
Cohort Study: The risk of stroke is substantially higher in the first year of initiation of oral contraceptives or hormone replacement therapy.
27 Jun, 2022 | 11:44h | UTCOral Contraceptives, Hormone Replacement Therapy, and Stroke Risk – Stroke (link to abstract – $ for full-text)
Commentary: Flash of Greater Stroke Risk at Initiation of Oral Contraceptives — Risk with hormone replacement therapy lingers in the long run, though – MedPage Today (free frustration required)
Transcranial magnetic stimulation of the brain: What is stimulated? – A consensus and critical position paper.
27 Jun, 2022 | 11:36h | UTC
Commentary on Twitter
[Transcranial magnetic stimulation (TMS)] Siebner et al.: "Myelinated axon terminals of pyramidal cells and inhibitory interneurons in the crown of the gyri constitute low-threshold targets for TMS."https://t.co/1UfzuAHlPj@DRCMR_MRIhttps://t.co/LzHAzeGMZ5 https://t.co/n5hPOlFNlL pic.twitter.com/szdY77WieS
— IFCN and its Clinical Neurophysiology journals (@ClinicalNeuroph) May 21, 2022
M-A: Safety and efficacy of SSRIs in improving poststroke recovery.
27 Jun, 2022 | 10:58h | UTC
Consensus Recommendations: Early management of patients with aneurysmal subarachnoid hemorrhage in a hospital with neurosurgical/neuroendovascular facilities.
22 Jun, 2022 | 11:25h | UTC
Cohort Study: Cardiometabolic multimorbidity, genetic risk, and dementia.
21 Jun, 2022 | 11:01h | UTCNews Release: Multiple heart-related conditions linked to triple dementia risk regardless of genetics – University of Oxford
Related:
Genetic Risk, Midlife Life’s Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study – Neurology (link to abstract – $ for full-text) AND Commentary: Seven healthy habits linked to lower risk of dementia in those with genetic risk – American Academy of Neurology
Preventing dementia: what’s the evidence? – Evidently Cochrane
Cohort Study: Association of cardiovascular risk trajectory with cognitive decline and incident dementia.
21 Jun, 2022 | 10:58h | UTCCommentary: Heart Risk Factors Can Be Recipe for Dementia – HealthDay
Related:
Genetic Risk, Midlife Life’s Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study – Neurology (link to abstract – $ for full-text) AND Commentary: Seven healthy habits linked to lower risk of dementia in those with genetic risk – American Academy of Neurology
Preventing dementia: what’s the evidence? – Evidently Cochrane
Commentary on Twitter
Study findings show that the longitudinal, cumulative trajectory of #cardiovascular risk is predictive of #dementia risk and associated with the emergence of memory decline. Read the article: https://t.co/CT1NQ63sXO #NeuroTwitter pic.twitter.com/KMGAPLQFe7
— Neurology Journal (@GreenJournal) May 17, 2022
Cohort Study: Cardiometabolic multimorbidity linked to accelerated cognitive decline and dementia progression.
21 Jun, 2022 | 10:59h | UTCNews Release: Diabetes and cardiovascular disease increase dementia risk – Karolinska Institutet
Related:
Genetic Risk, Midlife Life’s Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study – Neurology (link to abstract – $ for full-text) AND Commentary: Seven healthy habits linked to lower risk of dementia in those with genetic risk – American Academy of Neurology
Preventing dementia: what’s the evidence? – Evidently Cochrane
Summary of the new 2022 AHA/ASA Guideline on intracerebral hemorrhage.
21 Jun, 2022 | 10:54h | UTCIntracerebral Hemorrhage 2022 Guideline Update – emDocs
Original Guideline: 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association – Stroke
Top Things to Know: 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage – American Heart Association
News Release: New guideline refines care for brain bleeds: compression socks, some meds not effective – American Heart Association
Associations of bilateral vestibulopathy with cognition in older adults matched with healthy controls for hearing status.
21 Jun, 2022 | 10:24h | UTC
Commentary on Twitter
In this study, older adults with #bilateralvestibulopathy had worse #cognition than their matched control. These results support an association between vestibular loss and cognitive impairment, in particular #Alzheimerdisease. https://t.co/atHR8QlWD9
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) June 17, 2022
Acute shortage of iodinated contrast media: implications and guidance for neurovascular imaging and intervention.
20 Jun, 2022 | 01:20h | UTCRelated Guidance:
Short-, Mid-, and Long-Term Strategies to Manage the Shortage of Iohexol – Radiology
Related Study:
Comparison of Strategies to Conserve Iodinated Intravascular Contrast Media for Computed Tomography During a Shortage – JAMA (free for a limited period) AND News Release: Amid Global Shortage, Study Shows How to Cut Contrast Dye Use 83% – University of California, San Francisco (UCSF)
Systematic Review: Clinical judgement by primary care physicians for the diagnosis of all‐cause dementia or cognitive impairment in symptomatic people.
20 Jun, 2022 | 01:18h | UTCSummary: Why is improving dementia diagnosis important? – Cochrane Library
RCT: Safety and efficacy of Eptinezumab for migraine prevention in patients with two-to-four previous preventive treatment failures.
20 Jun, 2022 | 01:01h | UTCSafety and efficacy of eptinezumab for migraine prevention in patients with two-to-four previous preventive treatment failures (DELIVER): a multi-arm, randomised, double-blind, placebo-controlled, phase 3b trial – The Lancet Neurology (link to abstract – $ for full-text)
Artificial intelligence may detect autism speech patterns across different languages, study finds.
20 Jun, 2022 | 01:05h | UTCNews Release: AI detects autism speech patterns across different languages – Northwestern University
Original Study: Cross-linguistic patterns of speech prosodic differences in autism: A machine learning study – PLOS One
Registry-based cohort study: Endovascular treatment vs. best medical management in acute basilar artery occlusion strokes.
17 Jun, 2022 | 11:03h | UTCEndovascular Treatment Versus Best Medical Management in Acute Basilar Artery Occlusion Strokes: Results From the ATTENTION Multicenter Registry – Circulation (free for a limited period)
Commentary on Twitter
#ResearchLetter In 2134 patients with basilar artery occlusion #stroke, endovascular treatment was associated with improved functional capacity. The effect was more pronounced in patients with more debilitating symptoms #AHAJournals https://t.co/wy4uFocYlR pic.twitter.com/TIBRVAXRhE
— Circulation (@CircAHA) June 10, 2022