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Nephrology

Cohort Study | Patients diagnosed with diabetes by oral glucose tolerance test without elevated HbA1c had similar cardiovascular and renal disease risks as those without diabetes.

15 Sep, 2022 | 13:12h | UTC

Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study – Circulation

Commentary: Patients diagnosed by OGTT without elevated HbA1c had similar CV, renal disease risks as those without diabetes – ACP Diabetes

 

Commentary on Twitter

 


Review | Postoperative acute kidney injury.

15 Sep, 2022 | 13:00h | UTC

Postoperative AKI – Clinical Journal of the American Society of Nephrology

 


Systematic Review | Hypoxia‐inducible factor stabilizers for the anemia of chronic kidney disease.

8 Sep, 2022 | 14:35h | UTC

Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease – Cochrane Library

Summary: Are hypoxia-inducible factor stabilisers effective for management of anaemia among people with chronic kidney disease? – Cochrane Library

 


Brief Review | Monitoring of renal perfusion.

5 Sep, 2022 | 14:27h | UTC

Monitoring of renal perfusion – Intensive Care Medicine

 

Commentary on Twitter

 


M-A | The impact of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury on mortality and clinical outcomes.

1 Sep, 2022 | 11:33h | UTC

The impact of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury on mortality and clinical outcomes: a meta-analysis – Clinical Kidney Journal

Related:

Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial – The Lancet (link to abstract – $ for full-text)

Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury – New England Journal of Medicine

Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials – The Lancet

Timing of renal replacement therapy initiation for acute kidney injury in critically ill patients: a systematic review of randomized clinical trials with meta-analysis and trial sequential analysis – Critical Care

Comparison between watchful waiting strategy and early initiation of renal replacement therapy in the critically ill acute kidney injury population: an updated systematic review and meta-analysis – Annals of Intensive Care

 


Review/Perspective | European hypertension guideline downgrading of beta-blockers is not justified.

31 Aug, 2022 | 11:51h | UTC

Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta-blockers is not justified – Blood Pressure

 


Guideline | Management of kidney transplant patients with HLA antibodies.

31 Aug, 2022 | 11:47h | UTC

European Guideline for the Management of Kidney Transplant Patients With HLA Antibodies: By the European Society for Organ Transplantation Working Group – Transplant International

 


Salt substitutes vs. regular salt: a quick look.

30 Aug, 2022 | 12:02h | UTC

Salt substitutes vs. regular salt: a quick look – Evidently Cochrane

Original Study: Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library

Related:

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Commentary on Twitter

 


Cohort Study | Comparing kidney health outcomes in children, adolescents, and adults with focal segmental glomerulosclerosis.

30 Aug, 2022 | 11:53h | UTC

Comparing Kidney Health Outcomes in Children, Adolescents, and Adults With Focal Segmental Glomerulosclerosis – JAMA Network Open

 

Commentary on Twitter

 


[News release – not published yet] #ESCCongres – RCT | Evening dosing of blood pressure medication not better than morning dosing.

29 Aug, 2022 | 12:30h | UTC

Evening dosing of blood pressure medication not better than morning dosing – European Society of Cardiology

Related Consensus Statement: Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension – Journal of Hypertension

Related study (conflicting results): Bedtime Hypertension Treatment Improves Cardiovascular Risk Reduction in Randomized Trial

 


Bedtime dosing of antihypertensive medications: systematic review and consensus statement. – “use of bedtime drug dosing of antihypertensive drugs should not be routinely recommended”.

29 Aug, 2022 | 12:28h | UTC

Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension – Journal of Hypertension

Related: Evening dosing of blood pressure medication not better than morning dosing – European Society of Cardiology

 


RCT | Acetazolamide resulted in faster decongestion in patients with acute decompensated heart failure with volume overload.

29 Aug, 2022 | 12:25h | UTC

Acetazolamide in Acute Decompensated Heart Failure with Volume Overload – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Acetazolamide improves decongestion in patients with acute decompensated heart failure – European Society of Cardiology

Commentary: Acetazolamide in Decompensated Heart Failure With Volume Overload – ADVOR – American College of Cardiology

 

Commentary on Twitter

 


RCT | Efficacy of potassium supplementation on the risk of peritonitis in hypokalemic patients receiving peritoneal dialysis.

26 Aug, 2022 | 13:25h | UTC

Efficacy of Potassium Supplementation in Hypokalemic Patients Receiving Peritoneal Dialysis: A Randomized Controlled Trial – American Journal of Kidney Diseases (link to abstract – $ for full-text)

 

Commentary on Twitter

 


A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial.

26 Aug, 2022 | 13:08h | UTC

A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial – Critical Care

Original Study: Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury – New England Journal of Medicine

Related:

Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials – The Lancet

RCT: Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury – waiting too long can be deleterious

Meta-analysis: Early initiation of renal replacement therapy is not associated with survival benefit in critically ill patients with acute kidney injury

 


Brief Review | New drugs for acute kidney injury.

25 Aug, 2022 | 11:58h | UTC

New drugs for acute kidney injury – Intensive Care Medicine

 


Review | Subphenotypes in acute kidney injury.

25 Aug, 2022 | 11:50h | UTC

Subphenotypes in acute kidney injury: a narrative review – Critical Care

 


Position Statement | Chronic kidney disease as cardiovascular risk factor in routine clinical practice.

24 Aug, 2022 | 14:14h | UTC

Chronic kidney disease as cardiovascular risk factor in routine clinical practice: a position statement by the Council of the European Renal Association – European Journal of Preventive Cardiology (PDF)

 


Guideline | Management of adults with diabetes on dialysis.

23 Aug, 2022 | 13:16h | UTC

Management of adults with diabetes on dialysis – Joint British Diabetes Societies for Inpatient Care (PDF)

News Release: Latest JBDS dialysis guideline published – Diabetes Times

 


Observational analysis shows chronic kidney disease is associated with increased risk of intracerebral hemorrhage.

23 Aug, 2022 | 13:12h | UTC

Association of Chronic Kidney Disease With Risk of Intracerebral Hemorrhage – JAMA Neurology (link to abstract – $ for full-text)

 


Review | Drug regimens of novel antibiotics in critically ill patients with varying renal functions.

23 Aug, 2022 | 12:49h | UTC

Drug Regimens of Novel Antibiotics in Critically Ill Patients with Varying Renal Functions: A Rapid Review – Antibiotics

 


AHA Scientific Statement | Cardiovascular effects of home dialysis therapies.

22 Aug, 2022 | 12:24h | UTC

Cardiovascular Effects of Home Dialysis Therapies: A Scientific Statement From the American Heart Association – Circulation

Top Things to Know: CV Effects of Home Dialysis Therapies – American Heart Association

Commentaries:

AHA Urges More Home-Based Dialysis in Advanced Kidney Failure – TCTMD

Improving Cardiovascular Outcomes in Patients Treated With Dialysis—Time to Go Home – American Heart Association

 

Commentary on Twitter (thread – click for more)

 


Review | Hemoperfusion in the intensive care unit.

22 Aug, 2022 | 11:56h | UTC

Hemoperfusion in the intensive care unit – Intensive Care Medicine

 


Cohort Study | Aldosterone linked to increased risk of chronic kidney disease progression and end-stage kidney disease.

19 Aug, 2022 | 16:09h | UTC

News Release: Aldosterone linked to increased risk of chronic kidney disease progression and end-stage kidney disease – European Society of Cardiology

Original Study: Aldosterone in chronic kidney disease and renal outcomes – European Heart Journal

Editorial: Aldosterone excess and cardiorenal risk: more common than appreciated – European Heart Journal

 

Commentary on Twitter

 


M-A | Performance of confirmatory tests for diagnosing primary aldosteronism.

18 Aug, 2022 | 12:54h | UTC

Performance of Confirmatory Tests for Diagnosing Primary Aldosteronism: a Systematic Review and Meta-Analysis – Hypertension

 

Commentary on Twitter

 


Network M-A | Efficacy and safety of 12 immunosuppressive agents for idiopathic membranous nephropathy in adults.

16 Aug, 2022 | 13:10h | UTC

Efficacy and safety of 12 immunosuppressive agents for idiopathic membranous nephropathy in adults: A pairwise and network meta-analysis – Frontiers in Pharmacology

Related:

Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome – Cochrane Library

Treatment of Idiopathic Membranous Nephropathy for Moderate or Severe Proteinuria: A Systematic Review and Network Meta-Analysis – International Journal of Clinical Practice

 


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