Nephrology
New WHO Guideline for the pharmacological treatment of hypertension in adults.
26 Aug, 2021 | 08:57h | UTCGuideline for the pharmacological treatment of hypertension in adults – World Health Organization
Commentary on Twitter (thread – click for more)
The number of adults aged 30-79 living with #hypertension has doubled from 650 million to 1.28 billion since 1990, according to a 🆕 comprehensive global 🌎🌍🌏 analysis of trends in hypertension prevalence, detection, treatment and control.
👉 https://t.co/MI48CX2kEO pic.twitter.com/ARpS8uipeY
— World Health Organization (WHO) (@WHO) August 25, 2021
Review: Acute and chronic hyponatremia.
25 Aug, 2021 | 08:50h | UTCAcute and Chronic Hyponatremia – Frontiers in Medicine
Related:
Podcast: Hyponatremia deconstructed
Guidelines for the Management of Exercise-Associated Hyponatremia
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.
25 Aug, 2021 | 08:56h | UTCCommentary: Global and national high blood pressure burden and control – The Lancet (free registration required)
Commentary on Twitter
Our new analysis within #NCDRisC on the #worldwide #hypertension #prevalence in last 30 yrs published in @TheLancet. The number of people with HTN doubled from 1990 with 626 million🕴️♀️ and 652 million 🕴️ in 2019. Control rates were ⬇️10% in some countries!https://t.co/FdjusD38X3 pic.twitter.com/famYphfqC8
— Maciej Banach (@maciejbanach) August 25, 2021
RCT: Catheter-based adrenal ablation remits primary aldosteronism.
25 Aug, 2021 | 08:52h | UTCCatheter-Based Adrenal Ablation Remits Primary Aldosteronism: A Randomized Medication-Controlled Trial – Circulation (free for a limited period)
Commentary on Twitter
#ResearchLetter: RCT data show catheter-based adrenal ablation effectively ⬇️ BP in primary aldosteronism comparable to spironolactone – A potential therapy for patients unable to tolerate medications? https://t.co/ImSAdnVtxE #AHAJournals pic.twitter.com/WSJjFpzKPo
— Circulation (@CircAHA) August 21, 2021
RCT: No effect of Vitamin D supplementation on kidney function in adults with prediabetes.
25 Aug, 2021 | 08:41h | UTCEffect of Vitamin D Supplementation on Kidney Function in Adults with Prediabetes: A Secondary Analysis of a Randomized Trial – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary on Twitter
Low circulating 25-hydroxyvitamin D concentration has been suggested as a risk factor for both type 2 diabetes and kidney disease. This study found that in persons with prediabetes, vitamin D supplementation did not affect progression of KDIGO risk scores https://t.co/e1EmP403TD pic.twitter.com/yEQjrvZr7A
— CJASN (@CJASN) August 24, 2021
Things we do for no reason: routinely holding metformin in the hospital.
25 Aug, 2021 | 08:43h | UTC
RCT: SGLT2 inhibition reduces the risk of hyperkalemia in patients with diabetes and chronic kidney disease.
24 Aug, 2021 | 08:57h | UTCEffects of canagliflozin on serum potassium in people with diabetes and chronic kidney disease: the CREDENCE trial – European Heart Journal (link to abstract – $ for full-text)
Commentary on Twitter
SGLT2 inhibition reduces the risk of serious hyperkalemia in people with diabetic kidney disease, which may enable greater use of RAAS inhibitors in CKD and/or heart failure
New CREDENCE data presented this week at #ESCCongress, now in @ESC_Journals:https://t.co/OEqnXTdBDi pic.twitter.com/zsanEFZVCy
— Brendon Neuen (@brendonneuen) August 23, 2021
Prioritizing Peritoneal Catheter Placement during the COVID-19 Pandemic – A Perspective of the American Society of Nephrology COVID-19 Home Dialysis Subcommittee.
18 Aug, 2021 | 08:52h | UTC
Commentary on Twitter
Those receiving dialysis are at high risk of COVID-19, but peritoneal dialysis is a way to lower risk. Perspective outlines importance of timely PD catheter insertion, which is facilitated by prioritizing operating room time and enhanced operator training https://t.co/Sy2pUShfNU pic.twitter.com/sGl7lkPnGI
— CJASN (@CJASN) August 17, 2021
Cohort study: cardiovascular and kidney outcomes across the glycemic spectrum – Prediabetes and T2D were independently associated atherosclerotic cardiovascular disease; substantial gradient of risk was observed across HbA1c levels.
18 Aug, 2021 | 08:36h | UTCCommentary: Cardiovascular and Kidney Outcomes in Diabetes and Prediabetes – American College of Cardiology
Benefits and risks of frequent or longer hemodialysis: weighing the evidence.
17 Aug, 2021 | 08:37h | UTC
Guideline Synopsis: Management of patients with microhematuria.
16 Aug, 2021 | 00:45h | UTCManagement of Patients With Microhematuria – JAMA (free for a limited period)
Original guideline: Microhematuria: AUA/SUFU Guideline
BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.
11 Aug, 2021 | 08:39h | UTCEffect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill PatientsThe BaSICS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Does Crystalloid Composition or Rate of Fluid Administration Make a Difference When Resuscitating Patients in the ICU? – JAMA (free for a limited period)
Video: Balanced Solution vs. Saline in Intensive Care Study
Commentary on Twitter
Among critically ill patients requiring fluid challenges, treatment with a balanced solution compared with saline solution did not significantly reduce 90-day mortality https://t.co/LNDtsxxiwB
— JAMA (@JAMA_current) August 10, 2021
Secondary analysis of RCT finds Dapagliflozin is safe for patients with stage 4 chronic kidney disease.
10 Aug, 2021 | 08:51h | UTCCommentaries:
No Increase in Risk With Dapagliflozin in Patients With Stage 4 CKD – HealthDay
Review: Rational fluid resuscitation in sepsis for the hospitalist.
6 Aug, 2021 | 09:53h | UTC
Study: many patients with small renal masses can be safely managed with active surveillance.
2 Aug, 2021 | 00:07h | UTCCommentary: More Data Support Active Surveillance for Small Renal Masses — Most patients avoided surgery with no metastasis, better focus on aggressive disease – MedPage Today (free registration required)
Review: Diabetes and the kidney.
27 Jul, 2021 | 03:16h | UTCDiabetes and the kidney – Clinical Medicine Journal
Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.
26 Jul, 2021 | 02:54h | UTCCommentary: Case Mounts for COVID Vaccine Boosters in Kidney Transplant Recipients – MedPage Today (free registration required)
Related:
[Preprint] 3rd AstraZeneca shot gives strong immunity.
Commentary on Twitter
JUST PUBLISHED @JAMANetwork
✔️N=159 kidney #transplant recipients
✔️3rd dose of #mRNA #Moderna #vaccine induced a #serologic response in 49% of kidney transplant recipients who did not respond after 2 doseshttps://t.co/NCDyraI98x#RealTimeCOVID19 @IDSAInfo @HIV_TID @AST_info— COVID-19 Real-Time Learning Network (RTLN) (@RealTimeCOVID19) July 24, 2021
Complications of renal interventions: a pictorial review of CT findings.
21 Jul, 2021 | 10:24h | UTCComplications of renal interventions: a pictorial review of CT findings – Insights into Imaging
Review: Acute kidney injury.
18 Jul, 2021 | 23:18h | UTCAcute kidney injury – Nature Reviews Disease Primers (free for a limited period)
Commentary on Twitter
Get Primed on #AcuteKidneyInjury with our NEW PrimeView, FREE to download this week https://t.co/4RAOOaB8ep pic.twitter.com/d5iHCcqJwY
— Nature Reviews Disease Primers (@DiseasePrimers) July 15, 2021
Pathophysiology of COVID-19-associated acute kidney injury.
16 Jul, 2021 | 10:52h | UTCPathophysiology of COVID-19-associated acute kidney injury – Nature Reviews Nephrology
Summary: SGLT2 inhibitors and GLP-1 receptor agonists established and emerging indications.
14 Jul, 2021 | 10:56h | UTCSGLT2 Inhibitors and GLP-1 Receptor Agonists: Indications – American College of Cardiology
Original review: SGLT2 inhibitors and GLP-1 receptor agonists: established and emerging indications – The Lancet (link to abstract – $ for full-text)
A UK expert consensus approach for managing symptomatic arteriovenous fistula (AVF) stenosis in hemodialysis patients.
14 Jul, 2021 | 10:55h | UTC
FDA Safety Alert: hydroxyethyl starch products should not be used unless adequate alternative treatment is unavailable.
14 Jul, 2021 | 10:48h | UTCCommentary: FDA Piles on New Warnings for Blood Volume Expanders – MedPage Today (free registration required)
Related: Hydroxyethyl-starch Solutions (HES) Should no Longer be Used – European Medicines Agency AND Randomized Trial: Hydroxyethyl Starch vs. Saline for Volume Replacement Therapy in High-Risk Patients Undergoing Major Abdominal Surgery AND Systematic Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People
2021 ACR Guideline for the Management of ANCA–Associated Vasculitis.
9 Jul, 2021 | 10:09h | UTC
Systematic Review: Altered dietary salt intake for people with chronic kidney disease.
9 Jul, 2021 | 09:52h | UTCAltered dietary salt intake for people with chronic kidney disease – Cochrane Library
Summary: Altered dietary salt intake for adults with chronic kidney disease – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1410873135709278210