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Nephrology

RCT: Catheter-based adrenal ablation remits primary aldosteronism.

25 Aug, 2021 | 08:52h | UTC

Catheter-Based Adrenal Ablation Remits Primary Aldosteronism: A Randomized Medication-Controlled Trial – Circulation (free for a limited period)

 

Commentary on Twitter

 

RCT: No effect of Vitamin D supplementation on kidney function in adults with prediabetes.

25 Aug, 2021 | 08:41h | UTC

Effect of Vitamin D Supplementation on Kidney Function in Adults with Prediabetes: A Secondary Analysis of a Randomized Trial – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Things we do for no reason: routinely holding metformin in the hospital.

25 Aug, 2021 | 08:43h | UTC

Things We Do For No Reason™: Routinely Holding Metformin in the Hospital – Journal of Hospital Medicine

 

RCT: SGLT2 inhibition reduces the risk of hyperkalemia in patients with diabetes and chronic kidney disease.

24 Aug, 2021 | 08:57h | UTC

Effects of canagliflozin on serum potassium in people with diabetes and chronic kidney disease: the CREDENCE trial – European Heart Journal (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Prioritizing Peritoneal Catheter Placement during the COVID-19 Pandemic – A Perspective of the American Society of Nephrology COVID-19 Home Dialysis Subcommittee.

18 Aug, 2021 | 08:52h | UTC

Prioritizing Peritoneal Catheter Placement during the COVID-19 Pandemic – Clinical Journal of the American Society of Nephrology

 

Commentary on Twitter

 

Cohort study: cardiovascular and kidney outcomes across the glycemic spectrum – Prediabetes and T2D were independently associated atherosclerotic cardiovascular disease; substantial gradient of risk was observed across HbA1c levels.

18 Aug, 2021 | 08:36h | UTC

Cardiovascular and Kidney Outcomes Across the Glycemic Spectrum: Insights From the UK Biobank – Journal of the American College of Cardiology

Commentary: Cardiovascular and Kidney Outcomes in Diabetes and Prediabetes – American College of Cardiology

 

Benefits and risks of frequent or longer hemodialysis: weighing the evidence.

17 Aug, 2021 | 08:37h | UTC

Benefits and risks of frequent or longer haemodialysis: weighing the evidence – Nephrology Dialysis Transplantation

 

Guideline Synopsis: Management of patients with microhematuria.

16 Aug, 2021 | 00:45h | UTC

Management of Patients With Microhematuria – JAMA (free for a limited period)

Original guideline: Microhematuria: AUA/SUFU Guideline

 

BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.

11 Aug, 2021 | 08:39h | UTC

Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill PatientsThe BaSICS Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Does Crystalloid Composition or Rate of Fluid Administration Make a Difference When Resuscitating Patients in the ICU? – JAMA (free for a limited period)

Video: Balanced Solution vs. Saline in Intensive Care Study

 

Commentary on Twitter

 

Secondary analysis of RCT finds Dapagliflozin is safe for patients with stage 4 chronic kidney disease.

10 Aug, 2021 | 08:51h | UTC

Effects of Dapagliflozin in Stage 4 Chronic Kidney Disease – Journal of the American Society of Nephrology

Commentaries:

Dapagliflozin Found Effective and Safe in Adults with Advanced Kidney Disease – American Society of Nephrology

No Increase in Risk With Dapagliflozin in Patients With Stage 4 CKD – HealthDay

 

Review: Rational fluid resuscitation in sepsis for the hospitalist.

6 Aug, 2021 | 09:53h | UTC

A Narrative Review Rational Fluid Resuscitation in Sepsis for the Hospitalist: A Narrative Review – Mayo Clinic Proceedings

 

Study: many patients with small renal masses can be safely managed with active surveillance.

2 Aug, 2021 | 00:07h | UTC

Active Surveillance for Risk Stratification of All Small Renal Masses Lacking Predefined Clinical Criteria for Intervention – The Journal of Urology

Commentary: More Data Support Active Surveillance for Small Renal Masses — Most patients avoided surgery with no metastasis, better focus on aggressive disease – MedPage Today (free registration required)

 

Review: Diabetes and the kidney.

27 Jul, 2021 | 03:16h | UTC

Diabetes and the kidney – Clinical Medicine Journal

 

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

26 Jul, 2021 | 02:54h | UTC

Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses – JAMA

Commentary: Case Mounts for COVID Vaccine Boosters in Kidney Transplant Recipients – MedPage Today (free registration required)

Related:

Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

[Preprint] 3rd AstraZeneca shot gives strong immunity.

 

Commentary on Twitter

 

Complications of renal interventions: a pictorial review of CT findings.

21 Jul, 2021 | 10:24h | UTC

Complications of renal interventions: a pictorial review of CT findings – Insights into Imaging

 

Review: Acute kidney injury.

18 Jul, 2021 | 23:18h | UTC

Acute kidney injury – Nature Reviews Disease Primers (free for a limited period)

 

Commentary on Twitter

 

Pathophysiology of COVID-19-associated acute kidney injury.

16 Jul, 2021 | 10:52h | UTC

Pathophysiology of COVID-19-associated acute kidney injury – Nature Reviews Nephrology

 

Summary: SGLT2 inhibitors and GLP-1 receptor agonists established and emerging indications.

14 Jul, 2021 | 10:56h | UTC

SGLT2 Inhibitors and GLP-1 Receptor Agonists: Indications – American College of Cardiology

Original review: SGLT2 inhibitors and GLP-1 receptor agonists: established and emerging indications – The Lancet (link to abstract – $ for full-text)

Related guideline: SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes – This guidance recommends a risk-based approach, advising against starting SGLT-2 inhibitors or GLP-1 receptor agonists in patients with three or fewer cardiovascular risk factors and without established CVD or CKD.

 

A UK expert consensus approach for managing symptomatic arteriovenous fistula (AVF) stenosis in hemodialysis patients.

14 Jul, 2021 | 10:55h | UTC

A UK Expert Consensus Approach for Managing Symptomatic Arteriovenous Fistula (AVF) Stenosis in Haemodialysis Patients – CardioVascular and Interventional Radiology

 

FDA Safety Alert: hydroxyethyl starch products should not be used unless adequate alternative treatment is unavailable.

14 Jul, 2021 | 10:48h | UTC

Labeling Changes on mortality, kidney injury, and excess bleeding with hydroxyethyl starch products – U.S. Food and Drug Administration

Commentary: FDA Piles on New Warnings for Blood Volume Expanders – MedPage Today (free registration required)

Related: Hydroxyethyl-starch Solutions (HES) Should no Longer be Used – European Medicines Agency AND Randomized Trial: Hydroxyethyl Starch vs. Saline for Volume Replacement Therapy in High-Risk Patients Undergoing Major Abdominal Surgery AND Systematic Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People

 

2021 ACR Guideline for the Management of ANCA–Associated Vasculitis.

9 Jul, 2021 | 10:09h | UTC

2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis – Arthritis & Rheumatology

 

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

9 Jul, 2021 | 09:52h | UTC

Altered dietary salt intake for people with chronic kidney disease – Cochrane Library

Summary: Altered dietary salt intake for adults with chronic kidney disease – Cochrane Library

 

Commentary on Twitter

 

M-A: Incidence and Relapse of Idiopathic Nephrotic Syndrome.

7 Jul, 2021 | 08:37h | UTC

Incidence and Relapse of Idiopathic Nephrotic Syndrome: Meta-analysis – Pediatrics (link to abstract – $ for full-text)

 

Acute kidney injury in the critically ill: an updated review on pathophysiology and management.

5 Jul, 2021 | 01:49h | UTC

Acute kidney injury in the critically ill: an updated review on pathophysiology and management – Intensive Care Medicine

 

Commentary on Twitter

 

Podcast | Evaluation and management of hypercalcemia.

29 Jun, 2021 | 09:51h | UTC

#281 Hypercalcemia: Calci-fun! with Dr. Carl Pallais – The Curbsiders

 

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