Internal Medicine
The clinician’s guide to prevention and treatment of osteoporosis.
20 Jun, 2022 | 01:22h | UTCThe clinician’s guide to prevention and treatment of osteoporosis – Osteoporosis International
Brief Review: Helmet noninvasive support in hypoxemic respiratory failure.
20 Jun, 2022 | 01:13h | UTCHelmet noninvasive support in hypoxemic respiratory failure – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Helmet noninvasive support in hypoxemic respiratory failure:
⚙️ set‐up
⛑ physiology of helmet interface: from most relevant feature to major drawbacks
💨 clinical implications
Free to read #FOAMcc on @yourICM
🖇 https://t.co/qNE4Id5oBg pic.twitter.com/b2auLLlW9z— Intensive Care Medicine (@yourICM) June 18, 2022
Systematic Review: Clinical judgement by primary care physicians for the diagnosis of all‐cause dementia or cognitive impairment in symptomatic people.
20 Jun, 2022 | 01:18h | UTCSummary: Why is improving dementia diagnosis important? – Cochrane Library
RCT: Immune enhancement with Thymosin alpha 1 does not improve outcomes in patients with predicted severe acute necrotizing pancreatitis.
20 Jun, 2022 | 01:11h | UTCImmune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial – Intensive Care Medicine (if the link is paywalled, try this one)
AHA Scientific Statement: Revascularization for renovascular disease.
17 Jun, 2022 | 11:50h | UTCTop Things to Know: Revascularization for Renovascular Disease – American Heart Association
Commentary: When is Renovascular Hypertension Amenable to Revascularization – American Heart Association
Test-negative, case–control study: Effects of previous infection and vaccination on symptomatic omicron infections.
17 Jun, 2022 | 11:44h | UTCRelated:
Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 – New England Journal of Medicine
Two new studies show vaccination provides additional protection after Covid-19 infection.
Commentary on Twitter
A study in Qatar assessed the effectiveness of previous infection, vaccination, and both against symptomatic SARS-CoV-2 caused by omicron BA.1 and BA.2 and against severe, critical, or fatal #COVID19. https://t.co/bEVD3Y1sUn pic.twitter.com/Y38a0xxead
— NEJM (@NEJM) June 15, 2022
Incubation period for monkeypox: Estimates from the Netherlands.
17 Jun, 2022 | 11:41h | UTCNews Release: Incubation period for monkeypox: Estimates from the Netherlands – European Centre for Disease Prevention and Control (ECDC)
Original Study: Estimated incubation period for monkeypox cases confirmed in the Netherlands, May 2022 – Eurosurveillance
Commentary on Twitter (thread – click for more)
Our early investigation from @rivm on the incubation period for #monkeypox is now available @Eurosurveillanc.https://t.co/Vr9AChIAOV
Main finding: the mean incubation period was 8.5 days (5th to 95th percentiles: 4.2 to 17.3 days).
Details, caveats, and a few thoughts ⬇️🧵1/
— Fumi Miura (@FuminariMiura) June 16, 2022
Does this patient with acute infectious conjunctivitis have a bacterial infection? The rational clinical examination systematic review.
17 Jun, 2022 | 11:12h | UTCDoes This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection? The Rational Clinical Examination Systematic Review – JAMA (free for a limited period)
Commentary on Twitter
In this review, bacterial conjunctivitis was more common than viral conjunctivitis in children and viral conjunctivitis was more common than bacterial conjunctivitis in adults, although the prevalence estimates were based on limited evidence. https://t.co/wJ6YXxPRem
— JAMA (@JAMA_current) June 16, 2022
Cohort Study: Association of sitting time with mortality and cardiovascular events in high-income, middle-income, and low-income countries.
17 Jun, 2022 | 11:05h | UTCAssociation of Sitting Time With Mortality and Cardiovascular Events in High-Income, Middle-Income, and Low-Income Countries – JAMA Cardiology (free for a limited period)
Commentary: Trade the chair for fresh air: Sitting time and cardio health – Simon Fraser University
Commentary from one of the authors on Twitter
Our study in 105K people from #PURE study:
🌟⬆️ sitting associated with >early death & heart disease
🌟association > in low income countries
🌟being active can counteract risk
🌟every 30 min of sitting replaced by #exercise, risk⬇️ 2%#healthy@JAMACardio: https://t.co/rR61SolkXs pic.twitter.com/ESUFXy6Pvj— Scott Lear, PhD (@DrScottLear) June 15, 2022
Post Hoc Secondary Analysis of RCT: Rivaroxaban monotherapy is associated with better outcomes vs. combination therapy with antiplatelets in patients with atrial fibrillation and stable coronary artery disease.
17 Jun, 2022 | 11:07h | UTCRivaroxaban Monotherapy vs Combination Therapy With Antiplatelets on Total Thrombotic and Bleeding Events in Atrial Fibrillation With Stable Coronary Artery Disease: A Post Hoc Secondary Analysis of the AFIRE Trial – JAMA Cardiology (free for a limited period)
Commentaries:
Antithrombotic Therapy in Atrial Fibrillation and Coronary Artery Disease: Does Less Mean More? – JAMA Cardiology (free for a limited period)
Rivaroxaban Monotherapy Linked to Lower Event Risk in Patients with AF, Stable CAD – HCPLive
Commentary on Twitter
In this post-hoc study of the AFIRE RCT, recurrent event analyses showed that rivaroxaban monotherapy was associated with lower risks of total thrombotic and/or bleeding events than rivaroxaban plus antiplatelet therapy in patients with AF and stable CAD. https://t.co/TGwatvlrKR
— JAMA Cardiology (@JAMACardio) June 15, 2022
NICE Guideline: Reducing sexually transmitted infections.
16 Jun, 2022 | 11:15h | UTCReducing sexually transmitted infections – National Institute for Health and Care Excellence
Inappropriate sinus tachycardia: etiology, pathophysiology, and management.
16 Jun, 2022 | 11:05h | UTC
Perspective | Viruses that were on hiatus during Covid are back — and behaving in unexpected ways.
16 Jun, 2022 | 11:06h | UTCViruses that were on hiatus during Covid are back — and behaving in unexpected ways – STAT
RCT: Effect of legumes in energy reduced dietary approaches to stop hypertension (DASH) diet on blood pressure among overweight and obese type 2 diabetic patients.
16 Jun, 2022 | 10:41h | UTC
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses.
15 Jun, 2022 | 11:25h | UTC‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
See also: Rename monkeypox strains to remove geographic stigma, researchers say – Science
Related:
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
Review: Sepsis management for the nephrologist.
15 Jun, 2022 | 11:23h | UTCSepsis Management for the Nephrologist – Clinical Journal of the American Society of Nephrology
Pfizer’s Paxlovid study fails to answer key questions over benefit for broader populations.
15 Jun, 2022 | 11:22h | UTCPfizer’s Paxlovid study fails to answer key questions over benefit for broader populations – STAT
RCT: Effect of varenicline added to counseling on smoking cessation among African American daily smokers.
15 Jun, 2022 | 11:18h | UTCEditorial: Helping African American Individuals Quit Smoking: Finally, Some Progress – JAMA
News Release: Varenicline Increases Smoking Cessation Rates for African American Smokers – University of Kansas Cancer Center
Commentary on Twitter
Study found that, among African American adults who were daily smokers, counseling + 12 weeks of varenicline treatment, vs counseling + placebo, showed a significant improvement in rates of 7-day point prevalence smoking abstinence at week 26. https://t.co/fK4NUWgkJO
— JAMA (@JAMA_current) June 14, 2022
Analysis of thromboembolic and thrombocytopenic events after the AstraZeneca, Pfizer, and Moderna COVID-19 vaccines in 3 Nordic countries.
15 Jun, 2022 | 11:17h | UTC
Consensus Recommendations: Nomenclature and diagnosis of seronegative coeliac disease and chronic non-coeliac enteropathies in adults.
15 Jun, 2022 | 10:58h | UTC
Cross Sectional Study: Underdiagnosis and undertreatment of modifiable cardiovascular risk factors among survivors of childhood cancer.
15 Jun, 2022 | 10:43h | UTCCommentaries:
Survivors of Childhood Cancer More Likely to Be Undertreated for CVD Risk Factors – AMJC
RCT: Vonoprazan triple and dual therapy for Helicobacter pylori infection.
15 Jun, 2022 | 10:41h | UTCVonoprazan Triple and Dual Therapy for Helicobacter pylori Infection in the US and Europe: Randomized Clinical Trial – Gastroenterology (link to abstract – $ for full-text)
Encephalopathy in cirrhosis: prevention and management.
15 Jun, 2022 | 10:39h | UTC
Review: Portal vein thrombosis in cirrhosis.
15 Jun, 2022 | 10:38h | UTCPortal Vein Thrombosis in Cirrhosis – Journal of Clinical and Experimental Hepatology
Cohort Study | Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration.
15 Jun, 2022 | 10:34h | UTC