Internal Medicine | Page 100 of 487 | Links Medicus Content Curation & Alerts in Medicine

Two-thirds of individuals with sleep apnoea are multimorbid at diagnosis and one-third are heavily multimorbid. Dorsopathies, musculoskeletal diseases, hypertension and metabolic diseases are the most common comorbidities preceding sleep apnoea diagnosis. https://t.co/6MOud2ePbm pic.twitter.com/wyTukZAIxR

— ERS publications (@ERSpublications) June 7, 2022

Systematic Review: Recommendations of high-quality clinical practice guidelines related to the process of starting dialysis.

14 Jun, 2022 | 10:33h | UTC

Recommendations of high-quality clinical practice guidelines related to the process of starting dialysis: A systematic review – PLOS One

Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies.

14 Jun, 2022 | 10:30h | UTC

Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies – Neuropsychopharmacology

Commentary on Twitter

MA of RCTs: In patients with cancer pain no effect of cannabinoid administration on opioid dose was found (MD= −3.8 mg; −10.97 to 3.37) or % change in pain scores (MD=1.84; −2.05 to 5.72) https://t.co/tTckc0z8Oz pic.twitter.com/Gh7LvYRz0n

— P𝘧OL (@psychopharmacol) May 20, 2022

BSH guideline for the hematological management of major hemorrhage.

13 Jun, 2022 | 10:53h | UTC

A guideline for the haematological management of major haemorrhage: a British Society for Haematology Guideline – British Journal of Haematology

WHO Interim Guidance: Clinical management and infection prevention and control for monkeypox.

13 Jun, 2022 | 10:49h | UTC

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

M-A: Respiratory viral co-infections in patients with COVID-19 and associated outcomes.

13 Jun, 2022 | 10:41h | UTC

Respiratory viral co-infections in patients with COVID-19 and associated outcomes: A systematic review and meta-analysis – Reviews in Medical Virology

NIH Updated Guideline: Oxygenation and ventilation for adults with Covid-19.

13 Jun, 2022 | 10:44h | UTC

Oxygenation and Ventilation for Adults – National Institutes of Health

RCT: Intramuscular tixagevimab–cilgavimab may benefit non-hospitalized unvaccinated adults with Covid-19.

13 Jun, 2022 | 10:39h | UTC

Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Respiratory Medicine

Commentaries:

Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID – News Medical

Expert reaction to results of the TACKLE Phase 3 trial of Evusheld (tixagevimab and cilgavimab) for treating early COVID-19 in outpatients – Science Media Centre

Commentary on Twitter

NEW—A single intramuscular tixagevimab–cilgavimab dose provided protection against progression to severe COVID-19 or death vs placebo in unvaccinated individuals

TACKLE trial from Prof Hugh Montgomery & colleagues https://t.co/M9LENFsA2C pic.twitter.com/Aon4wJsBOi

— The Lancet Respiratory Medicine (@LancetRespirMed) June 8, 2022

Guidelines for the management of hypertension.

13 Jun, 2022 | 08:13h | UTC

2022 Guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the Management of Hypertension – Acta Cardiologica Sinica

One in 500 men carry extra sex chromosome, putting them at higher risk of several common diseases.

13 Jun, 2022 | 10:35h | UTC

News Release: One in 500 men carry extra sex chromosome, putting them at higher risk of several common diseases – University of Cambridge

Original Study: Detection and characterization of male sex chromosome abnormalities in the UK Biobank study – Genetics in Medicine

Commentary: One in 500 men carry extra sex chromosome, research suggests – The Guardian

Commentary on Twitter

Interesting work looking at the prevalence of male sex chromosomal abnormalities in UK Biobank.

"Only 49 of 213 (23%) of men whom we identified with KS and only 1 of 143 (0.7%) with 47,XYY had a diagnosis of abnormal karyotype on their medical records or self-report." https://t.co/3VKh2rqxyn

— Veera Rajagopal  (@doctorveera) June 11, 2022

Position Statement: Management of diabetic kidney disease.

13 Jun, 2022 | 08:09h | UTC

The 2021–2022 position of Brazilian Diabetes Society on diabetic kidney disease (DKD) management: an evidence-based guideline to clinical practice. Screening and treatment of hyperglycemia, arterial hypertension, and dyslipidemia in the patient with DKD – Diabetology & Metabolic Syndrome

Brief Review: Mental health morbidity, self-harm, and suicide in ICU survivors and caregivers.

13 Jun, 2022 | 08:01h | UTC

Mental health morbidity, self-harm, and suicide in ICU survivors and caregivers – Intensive Care Medicine (if the link is paywalled, try this one)

Commentary on Twitter

#ICU mental health outcomes? The more we discover, the more we realize we need to care for a vulnerable population!
🧠 mental health morbidity among survivors
🧠 mental health morbidity among caregivers
🧠 risk prediction/mitigation
🧠 future directions
🖇 https://t.co/wo8QdP8Mz9 pic.twitter.com/9jX6h9SdRz

— Intensive Care Medicine (@yourICM) June 7, 2022

SGLT2 inhibitor reduces the risk of hyperkalemia in patients with heart failure.

13 Jun, 2022 | 07:52h | UTC

Empagliflozin and serum potassium in heart failure: an analysis from EMPEROR-Pooled – European Heart Journal

Editorial: Emerging role for SGLT2 inhibitors in mitigating the risk of hyperkalaemia in heart failure

Commentary on Twitter

More evidence that SGLT2i ⬇️ hyperK, this time in heart failure

Empagliflozin reduces:
– K>6.0: HR 0.62 95% CI 0.48–0.81
– Investigator reported hyperK or K binders, HR 0.82 95% CI 0.71-0.95
– Effect modified by GFR – larger in CKD
– Regardless of MRAshttps://t.co/t4T7II1G8p pic.twitter.com/RP1EUKXHyV

— Brendon Neuen (@brendonneuen) June 12, 2022

Under a https://creativecommons.org/licenses/by-nc/4.0/ license

Systematic Review: Oxycodone for cancer‐related pain.

13 Jun, 2022 | 07:37h | UTC

Oxycodone for cancer‐related pain – Cochrane Library

Summary: Oxycodone for cancer-related pain in adults – Cochrane Library

RCT: Marine Omega-3 Fatty acid supplementation does not reduce the incidence of dry eye disease in healthy adults.

10 Jun, 2022 | 12:25h | UTC

Efficacy of Marine ω-3 Fatty Acid Supplementation vs Placebo in Reducing Incidence of Dry Eye Disease in Healthy US Adults: A Randomized Clinical Trial – JAMA Ophthalmology (free for a limited period)

Invited Commentary: Another Disappointment for ω-3 Fatty Acid and Dry Eye Disease – JAMA Ophthalmology (free for a limited period)

Commentary on Twitter

In this randomized clinical trial, daily supplementation with marine omega-3 fatty acids (1 gram) for a median of 5.3 years had no significant effect on the incidence of diagnosed #dryeyedisease (DED) or reported DED symptoms. https://t.co/iTBONh6CZK

— JAMA Ophthalmology (@JAMAOphth) June 9, 2022

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