Internal Medicine
Diabetes UK evidence-based nutrition guidelines for the prevention and management of diabetes
22 Mar, 2018 | 23:56h | UTCDiabetes UK evidence-based nutrition guidelines for the prevention and management of diabetes – Diabetic Medicine (free PDF for a limited period)
Commentary: New Diabetes UK Nutrition Guidance Supports Individual Approach – Medscape (free registration required)
Primary Care Physicians in the hospital
22 Mar, 2018 | 23:57h | UTCPCPs in the hospital – ACP Hospitalist (free)
Related study: Comparison of Hospital Resource Use and Outcomes Among Hospitalists, Primary Care Physicians, and Other Generalists – JAMA Internal Medicine (link to abstract – $ for full-text)
Pulmonary rehabilitation improves exercise tolerance in pulmonary fibrosis
22 Mar, 2018 | 23:52h | UTCPulmonary rehabilitation improves exercise tolerance in pulmonary fibrosis – NIHR Signal (free)
Original article: Impact of Pulmonary Rehabilitation on Exercise Tolerance and Quality of Life in Patients With Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis – Journal of Cardiopulmonary Rehabilitation and Prevention (link to abstract – $ for full-text)
Meta-analysis: Immune-related adverse events for anti-PD-1 and anti-PD-L1 drugs
22 Mar, 2018 | 23:51h | UTC
Meta-Analysis: Bedside ultrasound to detect central venous catheter misplacement and associated iatrogenic complications
22 Mar, 2018 | 23:45h | UTC
Viewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension
22 Mar, 2018 | 23:43h | UTCViewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension: Comparing the ADA and the ACC/AHA Recommendations – JAMA (free for a limited period)
A Quiet Drug Problem Among the Elderly
22 Mar, 2018 | 23:44h | UTCA Quiet Drug Problem Among the Elderly – The New York Times (free)
Related: Our Other Prescription Drug Problem – New England Journal of Medicine (free) AND Benzodiazepines: our other prescription drug epidemic – STAT (free)
“Despite warnings from experts, older people are using more anti-anxiety and sleep medications, putting them at risk of serious side effects and even overdoses”.
APROCCHSS: Hydrocortisone plus Fludrocortisone for Adults with Septic Shock
22 Mar, 2018 | 23:40h | UTCCommentary: APROCCHSS: Hydrocortisone plus Fludrocortisone for Adults with Septic Shock – The Bottom Line (free)
Original article: Hydrocortisone plus Fludrocortisone for Adults with Septic Shock – New England Journal of Medicine (link to abstract – $ for full-text)
Consensus Recommendations on Sulfonylurea and Sulfonylurea Combinations in the Management of Type 2 Diabetes Mellitus
22 Mar, 2018 | 23:35h | UTC
2018 ESC Guidelines for the diagnosis and management of syncope
19 Mar, 2018 | 13:12h | UTC2018 ESC Guidelines for the diagnosis and management of syncope – European Heart Journal (free for a limited period)
Related guideline: 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society (free)
Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops
16 Mar, 2018 | 03:37h | UTC#ACC18 – Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops – New England Journal of Medicine (free for a limited period)
Commentaries: Barbershop-Based Intervention Leads to Blood Pressure Reductions in African-American Men – American College of Cardiology (free) AND Mixing Haircuts and Hypertension Rx a ‘Home Run’ for Blood Pressure Control – TCTMD (free)
“Among black male barbershop patrons with uncontrolled hypertension, health promotion by barbers resulted in larger blood-pressure reduction when coupled with medication management in barbershops by specialty-trained pharmacists”.
Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care
16 Mar, 2018 | 03:36h | UTC#ACC18 – Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care – American College of Cardiology (free) AND Low-Dose, Three-Drug Polypill TRIUMPHs for Blood Pressure – TCTMD (free)
Do Antidepressants Work?
16 Mar, 2018 | 03:36h | UTCDo Antidepressants Work? – The New York Times (10 articles per month are free)
“The most comprehensive study on them has recently been published, showing mostly modest effects”.
See related meta-analysis and commentaries in our February 23rd issue (see #3)
Did a pricey cholesterol-lowering drug really reduce deaths, as headlines claim?
16 Mar, 2018 | 03:33h | UTCSee original article and commentaries in our March 12th issue (see #2)
The ODYSSEY Trial Ends Well— But Will It Be Enough?
16 Mar, 2018 | 03:32h | UTC#ACC18 – The ODYSSEY Trial Ends Well— But Will It Be Enough? – Cardiobrief (free) AND Ten Quick Thoughts on ODYSSEY – John Mandrola, via Medscape (free registration required)
“An absolute risk reduction of 1.6% in the primary endpoint translates to a number needed to treat of 64. Using the current price of $14,500 per year, Kaul calculated that preventing one event over the trial period of almost 3 years would cost about $2.6 million” (via John Mandrola). This study was presented at #ACC18 and has not been published yet. Among the many commentaries, these two were selected for a balanced point of view.
Research: Aromatherapy Versus Oral Ondansetron for Antiemetic Therapy
16 Mar, 2018 | 03:29h | UTCAromatherapy Versus Oral Ondansetron for Antiemetic Therapy Among Adult Emergency Department Patients: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentaries: Practice Changing: Inhaled Isopropyl Alcohol Superior to Oral Ondansetron as an Antiemetic – NEJM Journal Watch (free) AND Wake Up And Smell the Isopropyl – Emergency Medicine Literature of Note (free)
Research: Vitamin D and risk of total and site specific cancers
16 Mar, 2018 | 03:26h | UTC“Wake me up when there is a positive randomized trial of vitamin D pills for anything” (from Richard Lehman’s review).
Richard Lehman’s journal reviews – 12 March 2018
16 Mar, 2018 | 03:28h | UTCRichard Lehman’s journal reviews, 12 March 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Research: Inflammatory Bowel Disease Linked to Increased Risk in Heart Attack
16 Mar, 2018 | 03:18h | UTC#ACC18 – Inflammatory Bowel Disease Increases Likelihood of a Heart Attack – American College of Cardiology (free) AND Inflammatory bowel disease may raise heart attack risk – Medical News Today (free) AND Those with IBD twice as likely to have heart attack – Cardiovascular Business (free) AND Inflammatory Bowel Disease Makes Heart Attack Twice as Likely – Cardiosmart (free)
Meta-analysis: Getting flu shot may reduce deaths in heart failure
16 Mar, 2018 | 03:16h | UTC#ACC18 – Getting flu shot halves death risk for heart failure patients – Cardiovascular Business (free) AND Flu Vaccine Reduces Mortality, Hospitalization in HF Patients: Meta-analysis – TCTMD (free) AND Flu Shot Cuts Risk for Death by Half in Heart Failure – Medscape (free registration required) AND Getting Flu Vaccine Cuts Risk of Death by Half in People with Heart Failure – American College of Cardiology (free)
This meta-analysis of observational studies suggests a possible benefit.
Research: Hospital Readmission After Perioperative Acute Myocardial Infarction Associated With Noncardiac Surgery
16 Mar, 2018 | 03:20h | UTC#ACC18 – Hospital Readmission After Perioperative Acute Myocardial Infarction Associated With Noncardiac Surgery – Circulation (free PDF for a limited period)
Commentaries: Hospital Readmissions After Perioperative AMI – American College of Cardiology, Latest in Cardiology (free) AND Perioperative MIs Bring Too Many Patients Back to the Hospital After Noncardiac Surgery – TCTMD (free)
Research: Aspirin Lowers Risk of Death for Patients with Diabetes, Heart Failure
16 Mar, 2018 | 03:15h | UTC#ACC18 – Aspirin Lowers Risk of Death for Patients with Diabetes, Heart Failure – American College of Cardiology (free) AND Aspirin Linked to Lower Mortality in Diabetes With Heart Failure – Medscape (free registration required) AND ACC 2018: Aspirin Lowers Risk of Death in Patients With Diabetes and Heart Failure – PracticeUpdate (free registration required)
Guideline Summary: Peripheral Arterial Diseases
16 Mar, 2018 | 02:42h | UTCThe 2017 ESC Guidelines on PADs: what’s new? – European Heart Journal (free) AND The ‘Ten Commandments’ of 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases – European Heart Journal (free)
Original Guideline: 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS) (free)
Meta-Analysis: Dialysis Modality Survival Comparison
16 Mar, 2018 | 02:40h | UTCEditorial: Dialysis Modality Survival Comparison: Time to End the Debate, It’s a Tie – American Journal of Kidney Diseases (free)
Related commentary: PD or HD: Which Road Do We Take? – AJKD Blog (free)
Original article: Comparison of Patient Survival Between Hemodialysis and Peritoneal Dialysis Among Patients Eligible for Both Modalities – American Journal of Kidney Diseases (link to abstract – $ for full-text)
Source: Hemodialysis vs. Peritoneal Dialysis for End-Stage Renal Disease – NEJM Journal Watch ($)
Research: 6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome
16 Mar, 2018 | 02:29h | UTC#ACC18 – 6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (SMART-DATE): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: SMART-DATE: Myocardial Infarction Risk Higher with Six-Month Versus Twelve-Month DAPT – American College of Cardiology (free) AND Too Soon for 6-Month DAPT, Say SMART-DATE Investigators, Despite Positive Trial – TCTMD (free)
Related Guidelines: 2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy (free) AND 2017 European Society of Cardiology focused update on dual antiplatelet therapy in coronary artery disease (free) AND 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease (free)