Internal Medicine
Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality
30 Mar, 2018 | 03:30h | UTCCommentaries: Loneliness itself appears not to raise risk of heart attack/stroke – OnMedica (free) AND Association Between Loneliness, CV Events Often Explained by Conventional Risk Factors – Physician’s First Watch (free)
Summary: U.S. Preventative Services Task Force – Screening for Thyroid Cancer
30 Mar, 2018 | 03:29h | UTCSummary: U.S. Preventative Services Task Force – Screening for Thyroid Cancer: Recommendation Statement – American Family Physician (free)
A Systematic Review of the High-flow Nasal Cannula for Adult Patients
30 Mar, 2018 | 03:03h | UTCA Systematic Review of the High-flow Nasal Cannula for Adult Patients – Critical Care (free)
Association of Frailty With Failure to Rescue After Low-Risk and High-Risk Inpatient Surgery
30 Mar, 2018 | 02:39h | UTCAssociation of Frailty With Failure to Rescue After Low-Risk and High-Risk Inpatient Surgery – JAMA Surgery (link to abstract – $ for full-text)
Commentary: Frailty associated with failure to rescue after surgery, study finds – ACP Hospitalist (free)
Enriched food and snacks can increase nutritional intake in older people in hospital
30 Mar, 2018 | 02:39h | UTCEnriched food and snacks can increase nutritional intake in older people in hospital – NIHR Signal (free)
Original article: Can fortified foods and snacks increase the energy and protein intake of hospitalised older patients? A systematic review – Journal of Human Nutrition and Dietetics (link to abstract – $ for full-text)
Guideline: Tracheotomy in the intensive care unit
23 Mar, 2018 | 02:48h | UTC
Systematic Review: Are shorter courses of systemic steroids as effective as conventional longer courses in the treatment of patients with flare-ups of COPD?
23 Mar, 2018 | 02:50h | UTC“Information from a new large study has increased our confidence that five days of oral corticosteroids is likely to be sufficient for treatment of adults with acute exacerbations of COPD”.
Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism
23 Mar, 2018 | 02:51h | UTC
For hypertension and diabetes, lower treatment targets not necessarily better
23 Mar, 2018 | 02:47h | UTCRelated: AAFP Decides to Not Endorse AHA/ACC Hypertension Guideline (free) AND ACC/AHA Hypertension Guideline: What Is New? What Do We Do? – American Family Physician (free) AND Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)
Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation
23 Mar, 2018 | 02:46h | UTCThe 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation – European Heart Journal (free for a limited period)
News release: New EHRA Practical Guide on non-vitamin K antagonist oral anticoagulants launched (free)
When antibiotics turn toxic
23 Mar, 2018 | 02:43h | UTCWhen antibiotics turn toxic – Nature News (free)
“Commonly prescribed drugs called fluoroquinolones cause rare, disabling side effects. Researchers are struggling to work out why”.
Imaging is the only way to diagnose blood clots in pregnancy
23 Mar, 2018 | 02:39h | UTCCommentary: Imaging is the only way to diagnose blood clots in pregnancy – NIHR Signal (free)
“No blood test can accurately tell if a pregnant or recently pregnant woman has a blood clot. All pregnant women with a suspected clot should continue to have imaging investigations” (via @NIHR_DC see Tweet)
Low Back Pain – New Series from The Lancet Journals
23 Mar, 2018 | 02:41h | UTCLow Back Pain – New Series from The Lancet Journals
– Homepage and Executive Summary (free)
– Article 1: What low back pain is and why we need to pay attention (free registration required)
– Article 2: Prevention and treatment of low back pain: evidence, challenges, and promising directions (free registration required)
– Invited Commentary: Low back pain: a major global challenge (free registration required)
– Viewpoint: Low back pain: a call for action (free registration required)
Commentaries: Low Back Pain Affects 540 Million People Worldwide, but Too Many Patients Receive the Wrong Care – University of Warwick, via NewsWise (free) AND Lower back pain being treated badly on a global scale, study says – The Guardian (free)
Expert consensus on arrhythmias and cognitive function
23 Mar, 2018 | 02:36h | UTCCommentary: New Expert Statement on Arrhythmias and Cognitive Function – Medscape (free registration required)
Diastolic blood pressure and adverse outcomes in patients with heart failure with preserved ejection fraction who are treated for hypertension
23 Mar, 2018 | 02:34h | UTCDiastolic Blood Pressure and Adverse Outcomes in the TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) Trial – Journal of the American Heart Association (free for a limited period)
“DBP values ≥90 and <60 mm Hg are associated with a significant risk of adverse outcomes in patients with heart failure with preserved ejection fraction who are treated for hypertension”.
Systematic Review: Oral vitamin B12 compared with intramuscular vitamin B12
23 Mar, 2018 | 02:32h | UTCCommentary: Oral vs. Intramuscular Vitamin B12: Efficacy, Safety Compared – MPR (free)
Research: Tai chi versus aerobic exercise for fibromyalgia
23 Mar, 2018 | 02:02h | UTCCommentaries: Time to rethink exercise for fibromyalgia care – The BMJ Opinion (free) AND The unintended consequences of tai chi for fibromyalgia – The BMJ Opinion (free) AND Tai chi may be as effective for fibromyalgia as standard exercise – NHS Choices (free) AND Tai chi at least as beneficial as aerobic exercise for fibromyalgia – OnMedica (free)
Meta-Analysis: Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure
23 Mar, 2018 | 01:57h | UTCRelated study with similar conclusions: Impact of Cardiovascular Risk on the Relative Benefit and Harm of Intensive Treatment of Hypertension – Journal of the American College of Cardiology (link to abstract – $ for full-text)
“An intelligent approach towards blood pressure management: by the individual’s risk instead of just their measurements” (via @EricTopol see Tweet)
Screening for Skin Cancer: US Preventive Services Task Force Recommendation Statement
23 Mar, 2018 | 01:58h | UTCScreening for Skin Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)
Related Recommendation Statement: Behavioral Counseling to Prevent Skin Cancer: US Preventive Services Task Force (free)
JAMA Editorials: Sun Protection and Skin Self-examination and the US Preventive Services Task Force Recommendation on Behavioral Counseling for Skin Cancer Prevention (free) AND Should Pediatricians Be More Proactive in Counseling Children About Skin Cancer Risk? Implications of the USPSTF Recommendation Statement (free) AND The Potential of Behavioral Counseling to Prevent Skin Cancer (free) AND USPSTF Recommendations for Behavioral Counseling for Skin Cancer Prevention: Throwing Shade on UV Radiation (free) AND The Value of Behavioral Counseling for Skin Cancer Prevention: Actions We Can Take Now and Guidance for the Future (free)
Author Interviews: Screening for Skin Cancer (free audio) AND USPSTF Recommendation: Behavioral Counseling to Prevent Skin Cancer (free)
Commentaries: Doctors endorse counseling of some kids, young adults to prevent skin cancer – Reuters (free) AND Evidence insufficient to make recommendation regarding visual skin examination by a clinician – The JAMA Network, via EurekAlert (free)
Research: Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors
23 Mar, 2018 | 01:56h | UTCCommentaries: Survivors of childhood cancer are at great risk of heart problems in adulthood – eCancerNews (free) AND Higher heart risk for survivors of childhood cancer – OnMedica (free)
Related study: The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE) – The Lancet (link to abstract – $ for full-text)
Related Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)
Association of Inhaled Corticosteroids and Long-Acting β-Agonists as Controller and Quick Relief Therapy With Exacerbations and Symptom Control in Persistent Asthma
23 Mar, 2018 | 01:54h | UTCAssociation of Inhaled Corticosteroids and Long-Acting β-Agonists as Controller and Quick Relief Therapy With Exacerbations and Symptom Control in Persistent Asthma: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Related Meta-Analysis: Association of Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists With Asthma Control in Patients With Uncontrolled, Persistent Asthma: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Commentary: Reviews Reveal Benefits of LAMAs, LABAs, and SMART in Asthma – Medscape (free registration required)
Research: Physical activity, sedentary behaviour and colorectal cancer risk
23 Mar, 2018 | 01:51h | UTCPhysical activity, sedentary behaviour and colorectal cancer risk in the UK Biobank – British Journal of Cancer (link to abstract – $ for full-text)
Commentaries: Binge watching TV could increase bowel cancer risk in men – Imperial College London (free) AND Expert reaction to study on physical activity, sedentary behaviour and bowel cancer risk – Science Media Centre (free)
Richard Lehman’s journal review – 19 March 2018
23 Mar, 2018 | 01:50h | UTCRichard Lehman’s journal review, 19 March 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Research: associations of different adiposity measures with the incidence of cardiovascular disease
23 Mar, 2018 | 01:48h | UTCCommentaries: New study casts further doubt on the idea that you can be ‘fat and fit’ – NHS Choices (free) AND A ‘Sweet Spot’ for Heart Health – The New York Times (10 articles per month are free)
Research: Cardiovascular and renal burdens of prediabetes
22 Mar, 2018 | 23:58h | UTCCardiovascular and renal burdens of prediabetes in the USA: analysis of data from serial cross-sectional surveys, 1988–2014 – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Slightly elevated blood sugar tied to heart and kidney problems – Reuters (free) AND Study finds prediabetes patients at heightened risk for cardiovascular and chronic kidney diseases – MedicalXpress (free)


