Internal Medicine
Cohort Study: Pancreatic Cancer Following Incident Diabetes
22 Jun, 2018 | 02:31h | UTCPancreatic Cancer Following Incident Diabetes in African Americans and Latinos: The Multiethnic Cohort – Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentaries: Diabetes may be an early manifestation of pancreatic cancer – eCancer News (free) AND Recent-onset diabetes linked to pancreatic cancer for some minorities – UPI (free) AND Diabetes after 50 could be early sign of pancreatic cancer, study says – CNN (free)
Pharmacoepidemiological Study: Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms
22 Jun, 2018 | 02:28h | UTCAssociation of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study – Journal of Clinical Psychopharmacology (link to abstract – $ for full-text)
Commentaries: Incidence of Extrapyramidal Symptoms Higher With Certain Antidepressants – MPR (free) AND Antidepressants tied to Parkinson’s-like symptoms – Univadis (free registration required)
“Observational study: Incidence of EPSs with antidepressants. RRs: duloxetine, 5.68; mirtazapine, 3.78; citalopram, 3.47; escitalopram, 3.23; paroxetine, 3.07; sertraline, 2.57; venlafaxine, 2.37; bupropion, 2.31; and fluoxetine, 2.03 (all significant)” (via @psychopharmacol see Tweet)
Review: Surgical Treatment of Obesity
22 Jun, 2018 | 02:14h | UTCSurgical treatment of obesity – F1000 Research (free)
Review: Antiphospholipid Syndrome Nephropathy
22 Jun, 2018 | 02:13h | UTCAntiphospholipid Syndrome Nephropathy: From Pathogenesis to Treatment – Frontiers in Immunology (free)
Review: Pancreatic Cystic Lesions
22 Jun, 2018 | 02:10h | UTCPancreatic Cystic Lesions: Pathogenesis and Malignant Potential – Diseases (free)
Meta-Analysis: Cardiovascular Disease Risk Factors in Chronic Kidney Disease
22 Jun, 2018 | 02:06h | UTC“In addition to established traditional general population cardiovascular risk factors, left ventricular hypertrophy, serum albumin, phosphate, urate and hemoglobin were all found to be statistically significant in their association with future cardiovascular events”.
Update and Practical Messages: Systemic Lupus Erythematosus in Primary Care
22 Jun, 2018 | 02:08h | UTC
Review: How to Handle Patients with Bleeding Events While on Oral Antithrombotic Treatment
22 Jun, 2018 | 02:03h | UTCSource: Critical Care Reviews Newsletter
Review: Diuretic Resistance in Acute Heart Failure
22 Jun, 2018 | 01:59h | UTCDiuretic resistance in acute heart failure – European Heart Journal: Acute Cardiovascular Care (free PDF)
Clinical Review Podcast: Rethinking HbA1c Targets for Diabetes Treatment
19 Jun, 2018 | 22:32h | UTCPodcast (28 min): A Goal Too Far: Rethinking HbA1c Targets for Diabetes Treatment – JAMA Internal Medicine (free)
Related: For Patients with Type 2 Diabetes, What’s the Best Target Hemoglobin A1C? (Free Commentary, ADA Position Statement and ACP Guideline)
Review: Prevalence and Outcomes of Incidental Imaging Findings
19 Jun, 2018 | 22:28h | UTCPrevalence and outcomes of incidental imaging findings: umbrella review – The BMJ (free)
Related: Giles Maskell: Incidental anarchy – The BMJ Opinion (free)
“Incidentalomas. If you order imaging studies, you know they are a problem. This meta-analysis quantifies incidentaloma prevalence for specific types of imaging. For MRI of the brain, the prevalence was 22% (95%CI 14 to 31) (via @RasoiniR and @eloder, see Tweet)
Consensus Document: Management of Hyperkalemia in Patients with Cardiovascular Disease Treated with Renin Angiotensin Aldosterone System Inhibitors
19 Jun, 2018 | 22:31h | UTC
Commentary: Liberal vs Conservative Oxygen Therapy in the Critically Ill
19 Jun, 2018 | 22:26h | UTCIOTA – Liberal vs Conservative Oxygen Therapy in the Critically Ill – The Bottom Line (free)
Original Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)
“Hyperoxia is BAD –> Aim for lowest safest inspired O2 in critically ill pts & titrate FiO2 down if SpO2 >95%” (via @srrezaie see Tweet)
Meta-Analysis: Sex-specific Relevance of Diabetes to Occlusive Vascular and Other Mortality
19 Jun, 2018 | 22:25h | UTCCommentaries: Diabetes and cardiovascular mortality: the impact of sex – The Lancet Diabetes & Endocrinology (free) AND Diabetes triples women’s risk of death from ischemic heart disease – Cardiovascular Business (free)
Cohort Study: Influence of Lifestyle on Outcomes in Patients With Diabetes Mellitus
19 Jun, 2018 | 22:24h | UTCInfluence of Lifestyle on Incident Cardiovascular Disease and Mortality in Patients With Diabetes Mellitus – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Healthy Lifestyle Lowers CVD Risk in Diabetes Patients – American College of Cardiology (free) AND Healthy lifestyle changes after diabetes diagnosis lower CVD risk – Cardiovascular Business (free) AND Reduction in CVD Events, Even Mortality, in Patients With Diabetes Who Adopt a Healthier Lifestyle – TCTMD (free)
Consensus Document: Management of Arrhythmias and Cardiac Electronic Devices in the Critically Ill and Post-surgery Patient
18 Jun, 2018 | 23:22h | UTC
Cohort Study: Diagnosing Diabetes From a Single Blood Sample
19 Jun, 2018 | 22:23h | UTCPrognostic Implications of Single-Sample Confirmatory Testing for Undiagnosed Diabetes: A Prospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Diagnosing Diabetes From a Single Blood Sample – Johns Hopkins Bloomberg School of Public Health, via NewsWise (free) AND One Blood Test Might Be Enough to Diagnosis – HealthDay (free) AND Diabetes Dx Predicted Accurately with Single Blood Sample – MedPage Today (free registration required)
“The standard practice of repeat blood tests may not always be necessary, a new study suggests” (from Johns Hopkins Bloomberg School of Public Health)
Review: Secondary Peritonitis
18 Jun, 2018 | 23:21h | UTCSecondary peritonitis: principles of diagnosis and intervention – The BMJ (free)
Editorial: Helping Patients Choose Wisely
18 Jun, 2018 | 23:20h | UTCHelping patients choose wisely – The BMJ (free)
Related: The Choosing Wisely initiative was launched 5 years ago, and now has over 490 recommendations from 18 countries (free)
See complete lists from: Choosing Wisely U.S., Choosing Wisely UK, Choosing Wisely Australia AND Choosing Wisely Canada
“One of the main barriers to tackling the problem of overuse is that doctors are concerned patients will find it difficult to accept fewer interventions. However, informed patients often opt for less intervention, not more.” (via @bmj_latest see Tweet)
Randomized Trial: Medical Expulsive Therapy Not Effective for Kidney Stone Passage
18 Jun, 2018 | 23:18h | UTCEffect of Tamsulosin on Passage of Symptomatic Ureteral Stones: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Editorial: Medical Expulsive Therapy for Ureteral Stones—Stone Age Medicine (free)
Commentaries: Recent Clinical Trial Finds Tamsulosin Not Effective in Kidney Stone Passage – George Washington University, via NewsWise (free) AND For Passing Smaller Ureteral Stones, Tamsulosin May Be No Better Than Placebo – NEJM Physician’s First Watch (free)
Richard Lehman’s journal review, 18 June 2018
18 Jun, 2018 | 23:18h | UTCRichard Lehman’s journal review, 18 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Cohort Study: Outcomes in Acute Myocarditis
18 Jun, 2018 | 23:06h | UTCClinical Presentation and Outcome in a Contemporary Cohort of Patients with Acute Myocarditis: The Multicenter Lombardy Registry – Circulation (link to abstract – $ for full-text)
Commentary: Outcome of Acute Myocarditis Patients – American College of Cardiology (free)
“Retrospective study of 443 patients w/ acute myocarditis from 19 Italian hospitals reports relatively benign overall outcomes” (via @ACCinTouch see Tweet)
Randomized Trial: Metabolic Effects of Antipsychotics on Adiposity and Insulin Sensitivity in Youths
18 Jun, 2018 | 22:59h | UTCMetabolic Effects of Antipsychotics on Adiposity and Insulin Sensitivity in Youths: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Study First to Show Antipsychotic Medication Use in Youths Increases Diabetes Risk, Body Fat – Florida Atlantic University, via NewsWise (free) AND Rapid Weight Gain, Decreased Insulin Sensitivity Found in Youth Taking SGAs for First Time – Psychiatric News Alert (free) AND Kids on Antipsychotics May See Adverse Metabolic Effects – MedPage Today (free registration required)
Pearls for Evaluating Patients with New Venous Thromboembolism
18 Jun, 2018 | 22:58h | UTCPearls for Evaluating Patients with New Venous Thromboembolism – American College of Cardiology (free)
Randomized Trial: Duloxetine in Patients with Knee Osteoarthritis
18 Jun, 2018 | 10:08h | UTC