Internal Medicine
Guideline Synopsis: Management of Ventricular Arrhythmias and Sudden Cardiac Death Risk Associated With Cardiac Channelopathies
29 Jun, 2018 | 03:06h | UTCManagement of Ventricular Arrhythmias and Sudden Cardiac Death Risk Associated With Cardiac Channelopathies – JAMA Cardiology (free for a limited period)
Original Guideline: 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death – Circulation (free PDF)
USPSTF Statement: Screening for Osteoporosis to Prevent Fractures
29 Jun, 2018 | 02:52h | UTCEditorials: Screening for Osteoporosis (free) AND Osteoporosis Screening—2 Steps May Be Too Much for Women Younger Than 65 Years (free)
Author Interview: USPSTF Recommendation Statement: Screening for Osteoporosis to Prevent Fractures (free)
See also: USPSTF Final Recommendation Statement (free)
Randomized Trial: Closed-Loop Insulin Delivery for Glycemic Control in Noncritical Care
29 Jun, 2018 | 02:49h | UTCClosed-Loop Insulin Delivery for Glycemic Control in Noncritical Care – New England Journal of Medicine (free for a limited period)
Commentaries: Improved Glycemic Control With Closed-Loop Insulin Delivery System – Endocrinology Advisor (free) AND Closed-Loop Diabetes Systems (Artificial Pancreas) Can Be Used For Inpatient Care – MedicalResearch.com (free)
Review: Deprescribing Proton Pump Inhibitors
29 Jun, 2018 | 02:41h | UTCDeprescribing Proton Pump Inhibitors – Therapeutics Initiative (free)
Related guidelines: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing antipsychotics for behavioural and psychological symptoms of dementia and insomnia: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing benzodiazepine receptor agonists – Canadian Family Physician (free)
Randomized Trial: More Weight Loss Associated with Better Outcomes in Knee Osteoarthritis
29 Jun, 2018 | 02:39h | UTCCommentaries: Long-term weight loss of at least 20% helps improve outcomes in overweight, obese patients with knee osteoarthritis – ACP Internist (free) AND When it comes to weight loss in overweight and obese adults with knee osteoarthritis, more is better – Wiley, via ScienceDaily (free) AND More weight loss tied to less knee pain for obese people – Reuters (free) AND More Weight Loss Linked To Greater Decrease in Knee Arthritis Pain – MedicalResearch.com (free)
Case-Control Study: Hospital-at-Home Care Program Associated with Improved Outcomes and Patient Experiences
29 Jun, 2018 | 02:32h | UTCAssociation of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences – JAMA Internal Medicine (free for a limited period)
Editorial: Hospital-at-Home Care Programs—Is the Hospital of the Future at Home? (free for a limited period)
Author Interview: Association of a Bundled Hospital-at-Home Program With Clinical Outcomes and Patient Experiences (free)
Commentaries: Hospital-at-Home Bundled Program Associated With Better Clinical Outcomes, Patient Experiences – AJMC (free) AND Clinical outcomes and patient experiences vastly improved with hospital at home – The Mont Sinai Hospital (free) AND Hospital-at-Home Care a Potential Alternative to Inpatient Care – Physician’s First Watch (free)
Cohort Study: Accurately Measured Sodium Intake Showed a Linear Relationship with Mortality
29 Jun, 2018 | 02:27h | UTCErrors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health – International Journal of Epidemiology (link to abstract – $ for full-text)
Commentaries: Accurate measurements of sodium intake confirm relationship with mortality – ScienceDaily (free) AND Better estimate of intake more firmly links salt, death – UPI (free)
Related Report: Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks – Agency for Healthcare Research and Quality (free)
Guideline: Advance Care Planning in Dementia
29 Jun, 2018 | 02:30h | UTCRelated: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries) AND Alzheimer’s? Your Paperwork May Not Be in Order – The New York Times (free)
Richard Lehman’s journal review – 25 June 2018
29 Jun, 2018 | 02:24h | UTCRichard Lehman’s journal review, 25 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Systematic Review: Saline Irrigation for Allergic Rhinitis
29 Jun, 2018 | 02:25h | UTCSaline irrigation for allergic rhinitis – Cochrane Library (free)
Summary: Nasal saline for allergic rhinitis – Cochrane Library (free)
Review: Difficult Airway Management with Proposal of a Simplified Algorithm
29 Jun, 2018 | 02:21h | UTCRelated Guidelines: Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults – British Journal of Anaesthesia (free) AND Practice Guidelines for Management of the Difficult Airway: An Updated Report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway – Anesthesiology (free)
Review: Imaging of Abnormal Liver Function Tests
29 Jun, 2018 | 02:09h | UTCImaging of abnormal liver function tests – Clinical Liver Disease (free)
Systematic Review: Non-pharmacological Interventions to Improve Nighttime Sleep Among Residents of Long-Term Care Settings
29 Jun, 2018 | 02:10h | UTC
Review: The Venous Ulcer Continues to be a Clinical Challenge
29 Jun, 2018 | 02:08h | UTCThe venous ulcer continues to be a clinical challenge: an update – Burns & Trauma (free)
Related Cochrane Review: Dressings and topical agents for treating venous leg ulcers (free) AND Summary (free)
ESMO Guideline: Diarrhea in Adult Cancer Patients
24 Jun, 2018 | 19:34h | UTCDiarrhoea in adult cancer patients: ESMO Clinical Practice Guidelines – Annals of Oncology (free)
Retrospective Observational Study: Basal Insulin Analogs vs NPH Insulin for Type 2 Diabetes
24 Jun, 2018 | 19:27h | UTCAssociation of Initiation of Basal Insulin Analogs vs Neutral Protamine Hagedorn Insulin With Hypoglycemia-Related Emergency Department Visits or Hospital Admissions and With Glycemic Control in Patients With Type 2 Diabetes – JAMA (free for a limited period)
Editorial: Revisiting NPH Insulin for Type 2 Diabetes: Is a Step Back the Path Forward? (free for a limited period)
Clinical Review Audio: Health Care Spending Gone Wild: Using Expensive Insulin Analogs With Few Clinical Advantages (free)
“Long-acting insulin analogs not associated with reduced hypoglycemia-related ED visits or hospital admissions when compared with NPH insulin, despite costing 5-10x as much” (via @jsross119 see Tweet)
Report: Effects of Sodium and Potassium Intake on Chronic Disease Outcomes and Risks
22 Jun, 2018 | 02:53h | UTCSee also: Evidence Summary (free PDF) AND Full Report (free PDF)
Randomized Trial: Sodium Bicarbonate for Patients with Severe Metabolic Acidemia in the ICU
24 Jun, 2018 | 19:26h | UTCSodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: BICAR-ICU – The Bottom Line (free)
“This study will reassure clinicians that already use sodium bicarbonate for correcting metabolic acidaemia, that this may delay and/or reduce the requirement for RRT. Equally, for those that opt to avoid sodium bicarbonate, there is no compelling evidence to change practice”
Meta-Analysis: Determinants of Clinical Outcomes in Patients with Angina but Without Obstructive Coronary Artery Disease
24 Jun, 2018 | 19:23h | UTCCommentaries: Outcomes in Patients With Angina but Without Obstructive CAD – American College of Cardiology (free)
Review: What’s New in Severe Pulmonary Embolism?
22 Jun, 2018 | 02:40h | UTCWhat’s new in severe pulmonary embolism? – Intensive Care Medicine (free for a limited period) (via @srrezaie)
EULAR 2018: NSAIDs Account for Large Part of Osteoarthritis-CVD Link
22 Jun, 2018 | 02:50h | UTCNSAIDs Account for Large Part of Osteoarthritis-CVD Link, Study Suggests – TCTMD (free)
Review: Acute Myocardial Infarction in Young Women
22 Jun, 2018 | 02:38h | UTCRelated Review: Young Women With Acute Myocardial Infarction: Current Perspectives – Circulation: Cardiovascular Quality and Outcomes (free)
Related Guideline: Acute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association – Circulation (free)
NICE Guideline: Dementia
22 Jun, 2018 | 02:34h | UTC
Review: Managing Patients with Chronic Cough
22 Jun, 2018 | 02:37h | UTCSee also recently published CHEST guidelines on the management of cough in specific populations: Classification of Cough as a Symptom in Adults and Management Algorithms (free) AND Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold (free) AND Cough Due to TB and Other Chronic Infections (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis (free)
Register-Based Retrospective Cohort: Stress-Related Disorders Associated With Subsequent Autoimmune Disease
22 Jun, 2018 | 02:32h | UTCAssociation of Stress-Related Disorders With Subsequent Autoimmune Disease – JAMA (link to abstract – $ for full-text)
Commentaries: Association of Stress-Related Disorders With Subsequent Autoimmune Disease – University of Iceland (free) AND Stress disorders tied to increased risk of autoimmune diseases – Reuters (free) AND Does Psychological Stress Trigger Autoimmune Disorders? – MedPage Today (free registration required)