Internal Medicine
Review: Cardiovascular Risk in Patients with Rheumatoid Arthritis
24 Apr, 2018 | 19:31h | UTCState of the Art Review: Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications – The BMJ (free for a limited period)
Review: Management of Dyspnea in the Terminally Ill
24 Apr, 2018 | 18:03h | UTCManagement of Dyspnea in the Terminally Ill – CHEST (free PDF)
Source: Hospital Medicine Virtual Journal Club
Randomized Controlled Trial: Home vs Hospital Treatment of COPD Exacerbation
24 Apr, 2018 | 18:01h | UTCSource: Hospital Medicine Virtual Journal Club
Expert Analysis: Major Dyslipidemia Guidelines and Their Discrepancies
24 Apr, 2018 | 17:58h | UTC
Guideline: Diagnosis and Management of Primary Aldosteronism
23 Apr, 2018 | 21:17h | UTCDiagnosis and Management of Primary Aldosteronism: the Endocrine Society guideline 2016 revisited – European Journal of Endocrinology (free)
Hypokalemia: A Clinical Update
23 Apr, 2018 | 21:16h | UTCHypokalemia: a clinical update – Endocrine Connections (free)
New International Classification of Headache Disorders
23 Apr, 2018 | 21:14h | UTCHeadache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition – Cephalalgia (free PDF) (via @adamcifu)
News release and website: The International Classification of Headache Disorders 3rd edition (free)
Commentary: International Classification of Headache Disorders – The Lancet Neurology (free)
Randomized Trial: 5-Day Nitrofurantoin vs Single-Dose Fosfomycin in Uncomplicated Lower UTI
23 Apr, 2018 | 21:13h | UTCEditorial: Nitrofurantoin vs Fosfomycin: Rendering a Verdict in a Trial of Acute Uncomplicated Cystitis – JAMA (free)
Report: Role of Immunotherapy in the Treatment of Asthma
23 Apr, 2018 | 21:15h | UTCRole of Immunotherapy in the Treatment of Asthma – Agency for Healthcare Research and Quality (free)
Source: EvidenceAlerts
New Glasgow Coma Scale–Pupils Score
23 Apr, 2018 | 21:10h | UTCSimplifying the use of prognostic information in traumatic brain injury – Journal of Neurosurgery
Part 1: The GCS-Pupils score: an extended index of clinical severity (free)
Part 2: Graphical presentation of probabilities (free)
Commentaries: New Glasgow Coma Scale–Pupils Score and Multifactor Probability Outcome Charts for Use in Patients with TBI – Journal of Neurosurgery, via NewsWise (free) AND New scoring system will speed up assessment of brain injuries – OnMedica (free) AND Glasgow Coma Scale Gets an Eye-Opening Update – Medscape (free registration required)
Pancreatitis: Pearls & Pitfalls
23 Apr, 2018 | 20:59h | UTCPancreatitis: Pearls & Pitfalls – emDocs (free)
Related guidelines: American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis – Gastroenterology (free) AND Clinical practice guideline: management of acute pancreatitis – Canadian Journal of Surgery (free)
Meta-Analysis: Dual vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation following PCI
23 Apr, 2018 | 16:47h | UTCCompared with triple antithrombotic therapy, dual antithrombotic therapy shows a reduction in TIMI major or minor bleeding by 47% with comparable outcomes of major adverse cardiac events.
EuroPrevent 2018 Research: Exercise After a Heart Attack Could Save Your Life
23 Apr, 2018 | 16:46h | UTCOther commentaries: Regular exercise after heart attack might halve risk of death over next few years – OnMedica (free) AND It’s not too late: Exercise after heart attack cuts mortality risk – Cardiovascular Business (free) AND Remaining Active After MI May Help Stave Off Mortality – TCTMD (free)
“Becoming more physically active after a myocardial infarction halves the risk of dying within 4 years, study finds”
Cohort Study: Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality
20 Apr, 2018 | 02:02h | UTCEditorial: The Value in an Ambulatory Blood-Pressure Registry (free)
Commentaries: Value of Ambulatory BP Monitoring Bolstered by Large Study – TCTMD (free) AND 24-hour ambulatory BP measurements strongly predict mortality – The Hospitalist (free) AND Expert reaction to study looking at blood pressure measurement method and predicting risk of heart disease – Science Media Centre (free)
Guideline: Management of Acute Coronary Syndromes
20 Apr, 2018 | 01:53h | UTCSource: Critical Care Reviews Newsletter
Choosing Wisely: “Top 12” Recommendations That Are Reducing Overuse
20 Apr, 2018 | 01:50h | UTCThe “Top 12” Recommendations That Are Reducing Overuse – Choosing Wisely (free) (via @kennylinafp)
Learn more about the Choosing Wisely Initiative and see other lists of low-value practices in Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Choosing Wisely Campaigns: A Work in Progress
20 Apr, 2018 | 01:50h | UTCChoosing Wisely Campaigns: A Work in Progress – JAMA (free for a limited period) (via @ChooseWiselyCA see Tweet)
Guideline: Recommended Standard Care for People with Suicide Risk
20 Apr, 2018 | 01:47h | UTCNews Release: New Recommended Standard Care for People with Suicide Risk Aims to Fundamentally Improve Suicide Care Delivered Nationwide (free PDF)
Commentary: First-Ever Suicide Prevention Recommendations Released – Medscape (free registration required)
Cancer treatment in the last 6 months of life: when inaction can outperform action
20 Apr, 2018 | 01:46h | UTC
Research: Association of Repeated Measurements With Blood Pressure Control in Primary Care
20 Apr, 2018 | 01:43h | UTCAssociation of Repeated Measurements With Blood Pressure Control in Primary Care – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Repeat BP Measurements in the Office Are Key, Study Highlights – TCTMD (free) AND Should Blood Pressure Measurement Be Repeated During Primary Care Visit? – MedicalResearch.com (free) AND Second BP Measurement Often Brings Better News – MedPage Today (free registration required) AND Repeated BP Measures Linked to Drop in Initially Elevated BP – Physician’s Weekly (free)
Viewpoint: Another Nail in the Coffin for Fish Oil Supplements
20 Apr, 2018 | 01:36h | UTCAnother Nail in the Coffin for Fish Oil Supplements – JAMA (free for a limited period)
Systematic Review: First-line Drugs for Hypertension
20 Apr, 2018 | 01:34h | UTCFirst-line drugs for hypertension – Cochrane Library (free)
Summary: Thiazides best first choice for hypertension – Cochrane Library (free)
“First-line low-dose thiazides reduced all morbidity and mortality outcomes in adult patients with moderate to severe primary hypertension. First-line ACE inhibitors and calcium channel blockers may be similarly effective, but the evidence was of lower quality”.
Meta-Analysis: Baseline LDL Level and Total and Cardiovascular Mortality After LDL Lowering
20 Apr, 2018 | 01:31h | UTCAssociation Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: Patients With Highest LDL Levels Benefit Most From Lipid-Lowering Drugs – MedicalResearch.com (free) AND New Study Finds that Statins Prevent Cardiovascular Deaths – Science Based Medicine (free) AND Meta-Analysis: ‘Floor’ for Lipid-Lowering Mortality Benefits May Be Real – MedPage Today (free registration required)
“In meta-analyses of LDL-C lowering drug trials, we found that total and cardiovascular mortality were reduced only when the mean baseline LDL-C in the trial was >100 mg/dl” (from MedicalResearch.com)
BTS Quality Standards for Acute Non-invasive Ventilation in Adults
20 Apr, 2018 | 01:32h | UTCRelated Guidelines: Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting – Canadian Medical Association Journal (free) AND BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults – Thorax (free)
Source: Critical Care Reviews Newsletter
Systematic Review: Exercise Interventions and Patient Beliefs for People with Hip, Knee or Hip and Knee Osteoarthritis
18 Apr, 2018 | 01:09h | UTC