Internal Medicine
Meta-Analysis: Radial-Artery vs Saphenous-Vein Grafts in CABG
3 May, 2018 | 20:14h | UTCRadial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery – New England Journal of Medicine (free for a limited period)
Commentaries: More Data Show Benefits of Multiple Arterial Over Saphenous-Vein Grafting in CABG: Meta-analysis – TCTMD (free) AND Radial Artery or Saphenous Vein Grafts in CABG – American College of Cardiology (free)
Guideline: Optimal Use of Ionizing Radiation in Cardiovascular Imaging
3 May, 2018 | 20:05h | UTCCommentary: New Expert Consensus Document Provides Best Practices For Ionizing Radiation Safety – American College of Cardiology (free)
AHA Scientific Statement: Indications for Intracranial Endovascular Neurointerventional Procedures
3 May, 2018 | 20:07h | UTCKey Points to Remember: Indications for Intracranial Endovascular Procedures – American College of Cardiology (free)
Randomized Controlled Trial: Tenecteplase vs Alteplase before Thrombectomy for Ischemic Stroke
3 May, 2018 | 19:52h | UTCTenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Stroke: Which Clot Buster Drug Works Best? – MedicalResearch.com (free) AND Tenecteplase Appears Superior to Alteplase After Ischemic Stroke – Cardiology Advisor (free)
Cohort Study: Preventability of Early Versus Late Hospital Readmissions
3 May, 2018 | 19:54h | UTCPreventability of Early Versus Late Hospital Readmissions in a National Cohort of General Medicine Patients – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Hospital care quality more likely a factor in early versus late readmissions – ACP Hospitalist (free) AND Hospital readmissions occurring within 7 days post-discharge may be more preventable than later readmissions – 2 Minute Medicine (free)
Richard Lehman’s Journal Review – 30 April 2018
3 May, 2018 | 19:47h | UTCRichard Lehman’s journal review, 30 April 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Meta-Analysis: Predictors of Post-stroke Fever and Infections
3 May, 2018 | 19:38h | UTCCommentary: Predictors of poststroke pneumonia clarified – Univadis (free)
Review: Goodpasture’s syndrome (anti-GBM disease) in the ED
3 May, 2018 | 19:22h | UTCGoodpasture’s syndrome (anti-GBM disease): ED presentations, evaluation, and management – emDocs (free)
Lecture: How Less Health Care Can (Sometimes) Be Better For You
3 May, 2018 | 18:50h | UTCLecture: How Less Health Care Can (Sometimes) Be Better For You (free Youtube video)
See also other CLUE Working Group Lecture Series (tweet with lecture links by @KariTikkinen)
“Editor-in-Chief of @JAMAInternalMed, professor Rita Redberg gave the 3rd CLUE Working Group lecture entitled “How Less Health Care Can (Sometimes) Be Better For You” at the Think Corner of the U of Helsinki” (via @KariTikkinen see Tweet)
Polypharmacy Guidance, Realistic Prescribing
27 Apr, 2018 | 02:58h | UTCPolypharmacy Guidance, Realistic Prescribing 3 rd Edition, 2018 – Scottish Government Polypharmacy Model of Care Group (free PDF) (via @trishgreenhalgh)
Related Reviews: Current and future perspectives on the management of polypharmacy – BMC Family Medicine (free) AND Routine deprescribing of chronic medications to combat polypharmacy – Therapeutic Advances in Drug Safety (free) AND Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international (free) AND Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety (free)
“Just because we can, doesn’t mean we should” – supporting informed decision-making
27 Apr, 2018 | 02:56h | UTC
Guideline: Pharmacologic Glycemic Management of Type 2 Diabetes in Adults
27 Apr, 2018 | 02:59h | UTCGuideline: Pharmacologic Glycemic Management of Type 2 Diabetes in Adults – Canadian Journal of Diabetes (free)
Related Guidelines: ADA 2018 Standards of Medical Care in Diabetes (free) AND ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes (free)
In this new guideline Hemoglobin A1c Targets are similar from ADA 2018 Standards.
Randomized Controlled Trial: BNP Guided Therapy in Acute Decompensated Heart Failure
27 Apr, 2018 | 02:40h | UTCNT-proBNP (N-Terminal pro-B-Type Natriuretic Peptide)-Guided Therapy in Acute Decompensated Heart Failure – Circulation (link to abstract – $ for full-text)
Related Systematic Review: Effectiveness and cost-effectiveness of serum B-type natriuretic peptide testing and monitoring in patients with heart failure in primary and secondary care: an evidence synthesis, cohort study and cost-effectiveness model – Health Technology Assessment (free) AND Commentary: Uncertain benefits of BNP blood tests to monitor heart failure treatment – NIHR Signal (free)
Related AHA Scientific Statement: Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure (free)
Source: EvidenceAlerts
“NT Pro BNP guided heart failure treatment no better than usual care”. (via @doctorvec)
Review: Optimised Care of Elderly Patients with Acute Coronary Syndrome
27 Apr, 2018 | 02:39h | UTCOptimised care of elderly patients with acute coronary syndrome – European Heart Journal: Acute Cardiovascular Care (free) (via @krychtiukmd see Tweet)
Case-control Study: Anticholinergic Drugs and Risk of Dementia
27 Apr, 2018 | 02:38h | UTCAnticholinergic drugs and risk of dementia: case-control study – The BMJ (free)
Editorial: Anticholinergic drugs and dementia in older adults (free)
Commentaries: Expert reaction to study investigating the association between different types of anticholinergic drugs and risk of dementia – Science Media Centre (free) AND Anticholinergic drugs may be linked to increased risk of dementia – OnMedica (free)
“The effect of anticholinergic therapy is relatively small (odds ratio 1.1 – 1.2) and establishing an association does not prove a causal link. Nevertheless, the paper may act as a useful guide for future research and clinical practice”. (by Prof Les Iversen, in Science Media Centre)
Meta-Analysis: Probiotics for the Prevention of Clostridium difficile
27 Apr, 2018 | 02:36h | UTCCommentary: Probiotics may be safe, low-cost prevention tool for Clostridium difficile infections – News Medical (free)
Related Articles: The use of probiotics to prevent Clostridium difficile diarrhea associated with antibiotic use – Cochrane Library (free) AND Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients—A Systematic Review and Meta-Analysis – Antibiotics (free) AND Timely Use of Probiotics in Hospitalized Adults Prevents Clostridium difficile Infection: A Systematic Review With Meta-Regression Analysis – Gastroenterology (free)
Clinical Guideline: HIV Pre-exposure Prophylaxis
27 Apr, 2018 | 02:32h | UTCRelated guidelines: WHO implementation tool for pre-exposure prophylaxis of HIV infection – World Health Organization (free) AND Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis – Canadian Medical Association Journal (free) AND Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2017 Update: a Clinical Practice Guideline (free)
NICE Guideline Update: Neuropathic pain in adults
27 Apr, 2018 | 02:29h | UTCGuideline Update: Neuropathic pain in adults: pharmacological management in non-specialist settings – National Institute for Health and Care Excellence (free)
Research: Avoid Piperacillin-tazobactam When Treating BSI Caused by Ceftriaxone-resistant Pathogens
27 Apr, 2018 | 02:25h | UTC28th ECCMID: The MERINO Trial: piperacillin-tazobactam versus meropenem for the definitive treatment of bloodstream infections caused by third-generation cephalosporin nonsusceptible Escherichia coli or Klebsiella spp.: an international multi-centre openlabel non-inferiority randomised controlled trial (free abstract)
Commentaries: Avoid piperacillin-tazobactam when treating BSI cause by ceftriaxone-resistant pathogens – European Society of Clinical Microbiology and Infectious Diseases, via EurekAlert (free) AND Combo antibiotic found inferior for MDR bloodstream infections – CIDRAP (free)
Debate: Should we Recommend e-Cigarettes to Help Smokers Quit?
27 Apr, 2018 | 01:36h | UTCShould we recommend e-cigarettes to help smokers quit? – The BMJ (free)
See also: related guidelines, reports and commentaries on e-cigarettes
“Experts debate: Should doctors recommend e-cigarettes to help smokers quit? Revelation in harm reduction or a way to keep people addicted and gateway to youth smoking?” (via @rich_hurley see Tweet)
NICE Guideline Update: Diagnosis and Management of Epilepsies
27 Apr, 2018 | 01:34h | UTCGuideline Update: Epilepsies: diagnosis and management – National Institute for Health and Care Excellence (free)
NICE Guideline Update: Depression in adults
27 Apr, 2018 | 01:26h | UTCGuideline Update: Depression in adults: recognition and management – National Institute for Health and Care Excellence (free)
USPSTF Draft Recommendation: Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults
27 Apr, 2018 | 01:31h | UTCUSPSTF Draft Recommendation Statement: Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: Screening (free)
Commentaries: USPSTF urges abuse screening for reproductive-aged women – MedicalXpress (free) AND USPSTF Recommends Screening for Partner Violence in Reproductive-Aged Women – Clinical Advisor (free)
“The USPSTF recommends that clinicians screen for intimate partner violence (IPV) in women of reproductive age and provide or refer women who screen positive to ongoing support services.”
Things We Do For No Reason: Periprocedural Bridging Anticoagulation
27 Apr, 2018 | 01:25h | UTCThings We Do For No Reason: Periprocedural Bridging Anticoagulation – Journal of Hospital Medicine (free)
Perspective: Improving Emergency Department Care for Low-Risk Chest Pain
27 Apr, 2018 | 01:28h | UTCImproving Emergency Department Care for Low-Risk Chest Pain – NEJM Catalyst (free)