Internal Medicine
Randomized Trial: Intense IV Blood Sugar Control Doesn’t Improve Stroke Outcomes
11 Feb, 2019 | 00:15h | UTCCommentaries: NIH study provides answer to long-held debate on blood sugar control after stroke – National Institute of Health (free) AND Stroke: Intensive Blood Sugar Control Did Not Improve Outcomes – MedicalResearch.com (free) AND Live from the ISC: Standard treatment of hyperglycaemia in acute ischaemic stroke outperforms an intensive approach – NeuroNews (free)
Related Cochrane Review: Insulin for glycaemic control in acute ischaemic stroke (free) AND Summary: Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke (free)
“Intensive glucose control (80–130mg/dL) does not improve 90-day functional outcome and increases the risk of severe hypoglycaemia.” (from NeuroNews)
Five Warning Signs of Overdiagnosis
11 Feb, 2019 | 00:05h | UTCFive warning signs of overdiagnosis – The Conversation (free)
Related: Overdiagnosis: Causes and Consequences in Primary Health Care (free) AND Screening: How Overdiagnosis and Other Harms can Undermine the Benefits (free) AND WONCA Position Paper on Overdiagnosis and Action to be Taken (free) AND Overdiagnosis: what it is and what it isn’t (free) AND Review: Overdiagnosis Across Medical Disciplines (free) AND Too much medical care: bad for you, bad for health care systems (free)
Systematic Review: Managing Antidepressant Discontinuation
11 Feb, 2019 | 00:00h | UTCManaging Antidepressant Discontinuation: A Systematic Review – Annals of Family Medicine (free)
Commentary: Psychotherapy Ups Odds of Tapering Off Antidepressants – Medscape (free registration required)
Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine Learning
11 Feb, 2019 | 00:02h | UTCViewpoint: Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine Learning – JAMA (free for a limited period)
Related Commentary on Twitter
Excessive medical testing in the era of big data and precision medicine can lead to potential harms and unnecessary healthcare costs. @mandl & @arjunmanrai write an insightful @JAMA_current viewpoint on how to deal with this threat. https://t.co/uu1Cjwqy8n pic.twitter.com/L67aJhetCf
— Muin J. Khoury (@MuinJKhoury) February 8, 2019
Systematic Review Supports Lengthening of the Screening Interval of Patients with Type 2 Diabetes Without Retinopathy at Last Screening Session
10 Feb, 2019 | 23:58h | UTCCommentary: How often should patients with T2D be screened for retinopathy? – Univadis (free registration required)
Related: Evidence‐based Guidelines for Screening of Diabetic Retinopathy (free)
“This review supports lengthening of the screening interval of patients with Type 2 diabetes without retinopathy at last screening session”
Review: Cardiovascular Manifestations of Inflammatory Bowel Disease
10 Feb, 2019 | 15:41h | UTC
Cohort Study: Effect of Gastric Bypass Surgery on Diabetes Remission and Complications
10 Feb, 2019 | 15:44h | UTCEffect of Roux-en-Y gastric bypass surgery on diabetes remission and complications in individuals with type 2 diabetes: a Danish population-based matched cohort study – Diabetologia (free for a limited period)
Commentary: Gastric Bypass Surgery Linked to Diabetes Remission – MedicalResearch.com (free)
Study: Lifestyle Changes May be More Important than Drugs for Mild Hypertension
10 Feb, 2019 | 15:37h | UTCLifestyle changes may be more important than drugs for mild hypertension – NIHR Signal (free)
Original Study: Cohort Study: Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension (link to abstract and commentaries)
Clinical Practice Guidelines for Diagnosis and Management of Cough
10 Feb, 2019 | 14:35h | UTCRelated Guideline: KAAACI Evidence-Based Clinical Practice Guidelines for Chronic Cough in Adults and Children in Korea – Allergy, Asthma & Immunology Research (free)
See also recently published CHEST guidelines on the management of cough in specific populations: Classification of Cough as a Symptom in Adults and Management Algorithms (free) AND Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza – CHEST Guideline and Expert Panel Report (free) AND Clinically Diagnosing Pertussis-associated Cough in Adults and Children (free) AND Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold (free) AND Cough Due to TB and Other Chronic Infections (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis (free)
Expert Consensus on Diagnosis and Management of Severe Asthma
10 Feb, 2019 | 14:34h | UTCChinese expert consensus on diagnosis and management of severe asthma – Journal of Thoracic Disease (free)
Related Guidelines: Recognition and management of severe asthma: A Canadian Thoracic Society position statement (free) AND International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma (free) AND Guidelines for Severe Uncontrolled Asthma – Spanish Society of Pulmonology and Thoracic Surgery (free) AND Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults (free)
Study: Cardiovascular Risk Factors Associated With Venous Thromboembolism
10 Feb, 2019 | 13:48h | UTCCardiovascular Risk Factors Associated with Venous Thromboembolism – JAMA Cardiology (free)
“Older age, smoking, and adiposity were consistently associated with higher VTE risk.”
Expert Panel Recommendations: Fluid Administration for Acute Circulatory Dysfunction Using Basic Monitoring
7 Feb, 2019 | 23:26h | UTCFluid administration for acute circulatory dysfunction using basic monitoring: narrative review and expert panel recommendations from an ESICM task force – Intensive Care Medicine (free for a limited period)
Note: if the above link is paywalled, try this one
Related Commentary on Twitter
Fluid administration for acute circulatory failure: go back to the basics, thanks to the expert panel recommendations from an ESICM task force!
Read the full text article for free at https://t.co/VPtl6cD0aN @Dr_Cit @ESICM @ClinMedJournals pic.twitter.com/pBoJiKHihT— Intensive Care Medicine (@yourICM) February 1, 2019
Review: Diagnosis and Treatment of Primary Headache Disorders in Older Adults
7 Feb, 2019 | 22:50h | UTCSource: Medscape
Study: Patterns in Outpatient Benzodiazepine Prescribing
7 Feb, 2019 | 15:13h | UTCPatterns in Outpatient Benzodiazepine Prescribing in the United States – JAMA Network Open (free)
Commentary: Steep Climb In Benzodiazepine Prescribing By Primary Care Doctors – NPR (free)
Related: A Quiet Drug Problem Among the Elderly – The New York Times (10 articles per month are free) AND Benzodiazepines: our other prescription drug epidemic – STAT (free)
Consensus: Diagnosis of Peripheral Bone Infection in Adults
7 Feb, 2019 | 15:05h | UTC
BMJ Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain Does Not Improve Outcomes
7 Feb, 2019 | 02:03h | UTCCommentaries: Expert panel strongly recommends against surgery for the most common shoulder pain – MedicalXpress (free) AND Guidelines Recommend Against Surgery for Subacromial Pain Syndrome – NEJM Journal Watch (free)
Related Systematic Reviews: Subacromial decompression surgery for adults with shoulder pain: a systematic review with meta-analysis – British Journal of Sports Medicine (free) AND Subacromial Decompression Surgery for Rotator Cuff Disease – Cochrane Library (link to study and randomized trials on the subject)
Antibiotics may be an Alternative First-line Treatment for Uncomplicated Appendicitis
7 Feb, 2019 | 14:55h | UTCAntibiotics may be an alternative first-line treatment for uncomplicated appendicitis – NIHR Signal (free)
Original Study: Randomized Trial: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis (link to abstract, other studies, commentaries and a guideline on the subject)
Guideline: Acute Exacerbation of Bronchiectasis (Non-cystic Fibrosis)
7 Feb, 2019 | 01:07h | UTCRelated: British Thoracic Society Guideline for bronchiectasis in adults – Thorax (free)
Abdominal Wall Pain: A Common Clinical Problem
7 Feb, 2019 | 01:01h | UTCAbdominal Wall Pain: A Common Clinical Problem – Mayo Clinic Proceedings (free for a limited period)
Alex Nowbar’s research reviews – 5 February 2019
7 Feb, 2019 | 01:04h | UTCAlex Nowbar’s research reviews, 5 February 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Randomized Trial: Effect of Aerobic Exercise on Cognition in Younger Adults
7 Feb, 2019 | 00:45h | UTCEffect of aerobic exercise on cognition in younger adults: A randomized clinical trial – Neurology (link to abstract – $ for full-text)
Commentary: Exercise may improve thinking skills in people as young as 20 – American Academy of Neurology (free)
Position Statement: Comprehensive Management of Fibrotic Interstitial Lung Diseases
6 Feb, 2019 | 01:11h | UTCRelated: The interstitial lung disease multidisciplinary meeting: A position statement from the Thoracic Society of Australia and New Zealand and the Lung Foundation Australia (free) AND Interstitial Lung Disease and Pulmonary Fibrosis: A Practical Approach for General Medicine Physicians with Focus on the Medical History – Journal of Clinical Medicine (free) AND Pharmacological management of progressive-fibrosing interstitial lung diseases: a review of the current evidence – European Respiratory Review(free)
German Guidelines for the Treatment of Migraine Attacks and Prevention of Migraine
6 Feb, 2019 | 01:13h | UTCRelated Guidelines: Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society (free) AND Pharmacological management of migraine – Scottish Intercollegiate Guidelines Network (free)
Podcast: Hyperkalemia Master Class
6 Feb, 2019 | 00:52h | UTC#137 Hyperkalemia Master Class with Joel Topf MD – The Curbsiders Internal Medicine Podcast (free)
Meta-Analysis: Automated Office Blood Pressure Readings vs. Other Methods of Blood Pressure Measurement for Identifying Patients with Possible Hypertension
6 Feb, 2019 | 00:54h | UTCComparing Automated Office Blood Pressure Readings With Other Methods of Blood Pressure Measurement for Identifying Patients With Possible Hypertension: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Automated BP Readings More Accurate Than Manual Measurements – NEJM Journal Watch (free) AND Automated office BP readings best routine measures – MDedge Cardiology (free)
Related Commentary on Twitter
Automated office blood pressure readings, when recorded properly with the patient sitting alone in a quiet place, are more accurate than office BP readings in routine clinical practice and are similar to awake ambulatory BP readings @JAMAInternalMed https://t.co/iY5v4my94d
— Joseph Ross (@jsross119) February 4, 2019