Internal Medicine
Guideline: Treatment of Adult Obstructive Sleep Apnea with Positive Airway Pressure
17 Feb, 2019 | 21:40h | UTCNews Release: AASM publishes clinical practice guideline on use of PAP therapy for sleep apnea (free)
Related Podcast: Sleep Apnea Pearls and Pitfalls (free)
Canadian Guidelines on the Acute Management of ST-Elevation Myocardial Infarction: Focused Update on Regionalization and Reperfusion
17 Feb, 2019 | 21:34h | UTCRelated Guideline: 2018 ESC/EACTS Guidelines on myocardial revascularization – European Heart Journal (free)
Review: Managing Malignant Pleural Effusion
17 Feb, 2019 | 20:00h | UTCManaging malignant pleural effusion – Cleveland Clinic Journal of Medicine (free)
Related Guidelines: Management of Malignant Pleural Effusions. An Official ATS/STS/STR Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine (free) AND ERS/EACTS statement on the management of malignant pleural effusions – European Respiratory Journal (free)
Meta-Analysis: Vitamin D Supplementation to Prevent Acute Respiratory Infections
17 Feb, 2019 | 19:46h | UTC
Recommendations from European Breast Guidelines
17 Feb, 2019 | 19:47h | UTCRecommendations from European Breast Guidelines – European Commission Initiative on Breast Cancer (free)
News Release: New recommendations published: screening intervals and more (free)
Systematic Review: Management of Acute Respiratory Failure Due to Community-Acquired Pneumonia
17 Feb, 2019 | 19:40h | UTC
Chinese Guidelines on the Management of Ascites and its Related Complications in Cirrhosis
16 Feb, 2019 | 13:49h | UTCNote: if the above link is not working, try this one
Related Guidelines: Evidence-based clinical practice guidelines for liver cirrhosis 2015 – Journal of Gastroenterology (free) AND Management of Adult Patients with Ascites Due to Cirrhosis: Update 2012 – American Association for the Study of Liver Diseases (free PDF) EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis (free) AND KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications – Clinical and Molecular Hepatology (free) AND Cirrhosis in Over 16s: Assessment and Management – National Institute for Health and Care Excellence (free)
Meta-Analysis: Benefits and Harms of Pregabalin in the Management of Neuropathic Pain
15 Feb, 2019 | 00:51h | UTCRelated Cochrane Review (just published): Pregabalin for neuropathic pain in adults – Cochrane Library (free) and Commentary: Pregabalin for neuropathic pain: balancing benefits and harms – Evidently Cochrane (free)
BMJ Head to Head: Should We Screen for Atrial fibrillation?
15 Feb, 2019 | 00:52h | UTCShould we screen for atrial fibrillation? – The BMJ (free)
Commentary: Should we screen people for irregular heartbeat? – The BMJ, via ScienceDaily (free)
Related: USPSTF Statement: Screening with Resting or Exercise Electrocardiography (ECG) Not Recommended (free Guideline and commentaries) AND Wearable technology to screen for atrial fibrillation: does it raise more questions than it answers? (free commentaries) AND Get Ready For A Tsunami Of ECGs (free commentaries)
JAMA Clinical Guideline Synopsis: Diagnosis and Management of Infectious Diarrhea
15 Feb, 2019 | 00:48h | UTCGuideline Synopsis: Diagnosis and Management of Infectious Diarrhea – JAMA (free)
Original Guideline: 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea (free)
Related Guidelines: Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report (free) AND Guidelines for the Investigation of Chronic Diarrhoea in Adults: British Society of Gastroenterology (free)
Related Report: Global Burden of Diarrhea (free report and commentaries)
Deprescribing Benzodiazepine Receptor Agonists Taken for Insomnia
15 Feb, 2019 | 00:39h | UTCRelated: Guideline: Deprescribing Benzodiazepines (free guideline and resources) AND Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
https://twitter.com/JustinLeeMD/status/1095881022330322944?s=03
Observational Study Suggests Artificially Sweetened Beverages May Increase the Risk of Stroke, Coronary Heart Disease, and All-Cause Mortality
15 Feb, 2019 | 00:35h | UTCCommentaries: Diet drinks may be associated with strokes among post-menopausal women – American Heart Association (free) AND Post-menopausal women who drink diet soda have increased stroke risk – UPI (free) AND Artificially Sweetened Drinks Linked to Stroke, Heart Disease – NEJM Journal Watch (free)
Zackary Berger’s weekly research reviews – 13 February 2019
14 Feb, 2019 | 01:30h | UTCZackary Berger’s weekly research reviews, 13 February 2019 – The BMJ Opinion (free)
Review: Urine Sediment Examination in the Diagnosis and Management of Kidney Disease
13 Feb, 2019 | 02:06h | UTCUrine Sediment Examination in the Diagnosis and Management of Kidney Disease: Core Curriculum 2019 – American Journal of Kidney Diseases (free for a limited period)
Related Commentary on Twitter
Urine Sediment Examination in the Diagnosis and Management of Kidney Disease: Core Curriculum 2019 https://t.co/2gWvKYGi5p (FREE) @ccavanaugh87 @YaleMedicine pic.twitter.com/6aJxMVC88L
— AJKD (@AJKDonline) February 12, 2019
Severe Toxicity from Checkpoint Protein Inhibitors: What Intensive Care Physicians Need to Know?
13 Feb, 2019 | 02:02h | UTCRelated Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)
Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)
Randomized Trial: Intensive Blood Pressure Reduction Does Not Improve Outcomes in Patients with Acute Ischemic Stroke Treated with Thrombolytics
13 Feb, 2019 | 01:52h | UTCIntensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Intensive Blood Pressure Lowering With Intravenous Thrombectomy for Acute Ischemic Stroke Did Not Improve Functional Outcomes – Practical Neurology (free) AND Tighter BP Control No Better in Acute Stroke – MedPage Today (free registration required)
Australian Guideline for the Diagnosis and Management of Venous Thromboembolism
12 Feb, 2019 | 00:31h | UTCNews Release: New Guidelines for Venous Thromboembolism (free)
Related Guidelines: BTS Guideline: Outpatient Management of Pulmonary Embolism (free) AND ACEP Clinical Policy: Evaluation and Management of Suspected Acute Venous Thromboembolism (free) AND Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians (free) AND 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) (free)
Related Commentary on Twitter
https://twitter.com/theMJA/status/1094873925543092224
Review: Identifying and Managing Younger Women at High Risk of Cardiovascular Disease
12 Feb, 2019 | 00:21h | UTCIdentifying and managing younger women at high risk of cardiovascular disease – Canadian Medical Association Journal (free for 7 days)
Related Reviews: Knowledge, Attitudes, and Beliefs Regarding Cardiovascular Disease in Women: The Women’s Heart Alliance – Journal of the American College of Cardiology (free)
Related guidelines: Preventing and Experiencing Ischemic Heart Disease as a Woman: State of the Science: A Scientific Statement From the American Heart Association (free) AND Acute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association (free) AND AHA/ACOG: Reduction of Cardiovascular Disease in Women Through Collaboration with Obstetricians and Gynecologists (free)
Observational Study: Antibiotics Provide No Benefit for Hospitalized Asthma Patients, Linked to Longer Hospital Stay
12 Feb, 2019 | 00:04h | UTCAssociation of Antibiotic Treatment With Outcomes in Patients Hospitalized for an Asthma Exacerbation Treated With Systemic Corticosteroids – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Should Hospitalized Asthma Patients Receive Antibiotics? – MedicalResearch.com (free) AND No benefit of antibiotic treatment for hospitalised asthma patients – medwire News (free) AND Antibiotic therapy for asthma exacerbation associated with longer hospital stay – 2 Minute Medicine (free) AND Antibiotics Provide No Added Benefit in Severe Asthma Flares – ACEPNow (free)
Related Commentary on Twitter
“…although guidelines do not recommend #antibiotics for patients hospitalized with an #asthma exacerbation (unless [there are] clear signs of infection) 41% of patients receive #abx on day 1 of hospitalization." #FOAMed
Full story here: https://t.co/cLvpFgcmMZ pic.twitter.com/1x01e2awIb
— ACEP Members (@ACEPNow) February 8, 2019
Meta-Analysis: Effects of Dietary Improvement on Symptoms of Depression and Anxiety
11 Feb, 2019 | 23:43h | UTCCommentaries: Improved Diet Can Ease Depression Symptoms, Enhance Mood – PsychCentral (free) AND Many Different Diets Can Improve Mood And Reduce Depression Symptoms, Study Finds – Forbes (free) AND A diet rich in fiber and vegetables can relieve depression – Medical News Today (free)
Observational Study Suggests a Link Between Fruit and Vegetable Consumption and Mental Well-Being
11 Feb, 2019 | 23:41h | UTCCommentary: Hearts and minds: fruit and veg boost well-being – University of Leeds (free) AND Eating more fruit and veg ‘improves mental wellbeing’ – NHS Choices (free)
USPSTF Draft Recommendation Statement: Pancreatic Cancer Screening
11 Feb, 2019 | 21:06h | UTCDraft Recommendation Statement: Pancreatic Cancer Screening – U.S. Preventive Services Task Force (free)
Commentary: USPSTF Maintains Stance Against Routine Screening for Pancreatic Cancer – NEJM Journal Watch (free)
“The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults.”
Study: Only a Minority of Adults and Youth with T1D Achieve ADA goals for HbA1c
11 Feb, 2019 | 21:03h | UTCCommentary: Minority of patients with type 1 diabetes achieve ADA goals for glycemic control, study finds – ACP Diabetes (free)
Perspective: The Path to Diagnostic Excellence Includes Feedback to Calibrate How Clinicians Think
11 Feb, 2019 | 20:55h | UTCThe Path to Diagnostic Excellence Includes Feedback to Calibrate How Clinicians Think – JAMA (free for a limited period)
NICE Guideline: Antimicrobial Prescribing for Acute Cough
11 Feb, 2019 | 00:20h | UTCCough (acute): antimicrobial prescribing – National Institute for Health and Care Excellence (free)
Infographic: 2-page visual summary of the recommendations (free PDF)
See also: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)


