Internal Medicine
Guideline: Management of Sepsis in Neutropenic Cancer Patients
26 Feb, 2019 | 02:32h | UTCRelated Guidelines: SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018) – Clinical and Translational Oncology (free) AND Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update – Journal of Clinical Oncology (free) AND Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) (free) AND Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)
Meta-analysis: Performance of Fecal Immunochemical Tests for Colorectal Cancer Screening
26 Feb, 2019 | 02:15h | UTCPerformance Characteristics of Fecal Immunochemical Tests for Colorectal Cancer and Advanced Adenomatous Polyps: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Annual noninvasive stool test effective for colon cancer screening – Regenstrief Institute (free) AND Annual FIT home stool test effective for CRC screening rates – American College of Physicians (free) AND Meta-Analysis Adds Support for FIT for Colorectal Cancer Screening – NEJM Journal Watch (free) AND One-Time FIT Adequately Detects CRC but Not Advanced Adenomas – MedPage Today (free registration required)
Measuring Hospital-Acquired Complications Associated with Low-Value Care
26 Feb, 2019 | 02:17h | UTCMeasuring Hospital-Acquired Complications Associated With Low-Value Care – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Low-value procedures harm patients, consume hospital resources – HealthExec (free)
Nuances to the Management of Febrile Patients: Non-Infectious Causes of Fever
26 Feb, 2019 | 02:19h | UTCNuances to the Management of Febrile Patients: Non-Infectious Causes of Fever – emDocs (free)
Related: Pyrexia: aetiology in the ICU – Critical Care (free)
Guideline: Diagnosis and Management of Acute Lower Gastrointestinal Bleeding
25 Feb, 2019 | 01:20h | UTCRelated: ACG Clinical Guideline: Management of Patients With Acute Lower Gastrointestinal Bleeding (free)
Consensus Statement: Physical Activity and Ageing
25 Feb, 2019 | 01:19h | UTC
Updates in Management and Timing of Dialysis in Acute Kidney Injury
25 Feb, 2019 | 01:14h | UTCUpdates in Management and Timing of Dialysis in Acute Kidney Injury – Journal of Hospital Medicine (free PDF for a limited period)
Related Research: Early vs. Delayed Dialysis in Acute Kidney Injury (link to abstract and commentary)
FDA Adds Boxed Warning for Increased Risk of Death with Gout Medicine Febuxostat
25 Feb, 2019 | 01:15h | UTCCommentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)
Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)
Meta-Analysis: Pharmacological Treatments for Generalized Anxiety Disorder
25 Feb, 2019 | 01:11h | UTCPharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)
Commentary: Pharmacotherapy for Generalized Anxiety: An Update – NEJM Journal Watch (free for a limited period)
Report: Pharmacotherapy in Older Adults with Cardiovascular Disease
22 Feb, 2019 | 01:38h | UTC
Study: Preventing Misdiagnosis of Diabetes in the Elderly Through Age-dependent HbA1c Reference Intervals
22 Feb, 2019 | 01:36h | UTCCommentary: Should HbA1c cutoffs for DM diagnosis be higher in older adults? – Univadis (free registration required)
Related Commentary on Twitter
HbA1c increases with age in people without diabetes–should there be different cut-points for diagnosis of diabetes in elderly?https://t.co/5FvRXrMBvS@ABCDiab @IntDiabetesFed @DiabetesUK @ADA_DiabetesPro @DiabetesCanada @AmDiabetesAssn @AmarPut @parthaskar @drpatrickholmes
— Prof Kamlesh Khunti (@kamleshkhunti) February 16, 2019
Opinion – “Things We Do for No Reason: The Use of Thickened Liquids in Treating Hospitalized Adult Patients with Dysphagia”
22 Feb, 2019 | 01:21h | UTCSee Complete Series of Things We Do For No Reason (free articles)
What’s New in the ESC 2018 Guidelines for Arterial hypertension: The Ten Most Important Messages
21 Feb, 2019 | 04:08h | UTCRelated Summaries: Ten Commandments of the 2018 ESC/ESH Hypertension Guidelines (free) AND 2018 ESC/ESH Guidelines for Management of Arterial Hypertension – American College of Cardiology (free)
Original Guideline: ESC/ESH Guidelines for the Management of Arterial Hypertension (free)
Perspective: Understanding Lung Cancer Screening
21 Feb, 2019 | 03:54h | UTCUnderstanding Lung Cancer Screening – BMJ EBM Spotlight (free)
Consensus: Decision Tree for Diagnosis of Osteoarthritis in Primary Care
21 Feb, 2019 | 03:56h | UTC
USPSTF Draft Statement: BRCA-Related Cancer Risk Assessment, Genetic Counseling, and Genetic Testing
21 Feb, 2019 | 03:59h | UTCDraft Recommendation Statement: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing – U.S. Preventive Services Task Force (free)
Commentaries: USPSTF Issues Draft Recommendation on BRCA Risk Assessment and Testing – NEJM Journal Watch (free) AND New recommendations say not all women need genetic testing for cancer. Critics say it could cost lives – CNN (free)
Ann Robinson’s research reviews – 19 February 2019
20 Feb, 2019 | 03:06h | UTCAnn Robinson’s research reviews, 19 February 2019 – The BMJ Opinion (free)
Hospital Pharmacy: Choosing Wisely Canada New Recommendations Released
20 Feb, 2019 | 03:00h | UTCChoosing Wisely Canada: Six Things Clinicians and Patients Should Question – Canadian Society of Hospital Pharmacists (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Meta-Analysis: Proton Pump Inhibitors use and Risk of Chronic Kidney Disease
20 Feb, 2019 | 02:48h | UTCRelated Research (just published): Analysis of postmarketing safety data for proton-pump inhibitors reveals increased propensity for renal injury, electrolyte abnormalities, and nephrolithiasis – Scientific Reports (free) and Commentary: Common acid reflux medications linked to increased kidney disease risk – University of California (free)
See also: Proton Pump Inhibitors: Review of Emerging Concerns (free reviews) AND Deprescribing Proton Pump Inhibitors (free guidelines and reviews)
AGA Clinical Practice Guidelines on the Management of Mild-to-Moderate Ulcerative Colitis
18 Feb, 2019 | 23:57h | UTCSee also: AGA Technical Review on the Management of Mild-to-Moderate Ulcerative Colitis – Gastroenterology (free)
Commentary: New guideline recommendations for the treatment of mild-to-moderate ulcerative colitis – American Gastroenterological Association (free)
Podcast: Psychopharmacology 2.0, Antidepressant Master Class
18 Feb, 2019 | 23:39h | UTC#140 Psychopharmacology 2.0, Antidepressant Master Class – The Curbsiders Internal Medicine Podcast (free)
Guideline Summary: Deprescribing Cholinesterase Inhibitors and Memantine in Dementia
18 Feb, 2019 | 22:11h | UTCRelated: Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
Subclinical Hypothyroidism: When to Treat
18 Feb, 2019 | 21:49h | UTCSubclinical hypothyroidism: When to treat – Cleveland Clinic Journal of Medicine (free)
Related: Thyroid Hormone Treatment Does Not Help Adults with Mildly Abnormal Thyroid Tests (link to abstract and commentaries) AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (free study and commentary)
Podcast: Genetic Testing in Primary Care
18 Feb, 2019 | 17:01h | UTC#139 Genetic Testing in Primary Care – The Curbsiders Internal Medicine Podcast (free audio)
Acute Pulmonary Embolism: A Concise Review of Diagnosis and Management
18 Feb, 2019 | 16:59h | UTCAcute pulmonary embolism: a concise review of diagnosis and management – Internal Medicine Journal (free)
Related Guidelines: BTS Guideline: Outpatient Management of Pulmonary Embolism (free) AND ACEP Clinical Policy: Evaluation and Management of Suspected Acute Venous Thromboembolism (free) AND Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians (free) AND 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) (free)