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Internal Medicine

Study: Benefits of Statins Questioned for Primary Prevention of Cardiovascular Disease

30 Apr, 2019 | 02:35h | UTC

Statins for the primary prevention of cardiovascular disease: an overview of systematic reviews – BMJ Open (free)

Commentary: NNT with statins is 400 for lower risk eligible patients, researchers estimate – Pulse (free)

 


Management of Inflammatory Rheumatic Conditions in the Elderly

29 Apr, 2019 | 01:04h | UTC

Management of inflammatory rheumatic conditions in the elderly – Rheumatology (free)

 


Study: Half of Older Patients Starting Dialysis Die Within One Year

29 Apr, 2019 | 01:06h | UTC

One-Year Mortality After Dialysis Initiation Among Older Adults – JAMA Internal Medicine (free for a limited period)

Commentaries: Older Adults Starting Dialysis Die at Higher Rates than Previously Thought – Harvard Medical School (free) AND More than half of older dialysis patients die within a year – UPI (free)

 


2019 Chinese Guideline for the Management of Hypertension in the Elderly

28 Apr, 2019 | 13:35h | UTC

2019 Chinese guideline for the management of hypertension in the elderly – Journal of Geriatric Cardiology (free)

 


Contemporary Concise Review 2018: Asthma and COPD

28 Apr, 2019 | 13:27h | UTC

Contemporary Concise Review 2018: Asthma and chronic obstructive pulmonary disease – Respirology (free)

 


Review: Acute Management of Hyperkalemia

28 Apr, 2019 | 13:33h | UTC

Acute Management of Hyperkalemia – Current Heart Failure Reports (free)

Related: Management of Hyperkalemia in the Acutely Ill Patient (free reviews)

 


Cardiovascular Comorbidities in COPD—Current Considerations for Clinical Practice

28 Apr, 2019 | 13:29h | UTC

Cardiovascular Comorbidities in Chronic Obstructive Pulmonary Disease (COPD)—Current Considerations for Clinical Practice – Journal of Clinical Medicine (free)

 


Review: Determinants of Perioperative Outcome in Frail Older Patients

28 Apr, 2019 | 13:26h | UTC

Determinants of Perioperative Outcome in Frail Older Patients – Deutsches Ärzteblatt international (free)

 


Clinical Guideline for Urinary Stone Disease

26 Apr, 2019 | 02:09h | UTC

The Urological Association of Asia clinical guideline for urinary stone disease – International Journal of Urology (free)

Related: NICE Guideline – Renal and Ureteric Stones: Assessment and Management (free guidelines)

 


Randomized Trial: β Blockers to Prevent Decompensation of Cirrhosis in Patients with Portal Hypertension

26 Apr, 2019 | 02:07h | UTC

β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial – The Lancet (link to abstract – $ for full-text)

Commentary: Beta-blockers linked to better outcomes in some patients with cirrhosis – ACP Gastroenterology (free)

 


Systematic Review: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention

26 Apr, 2019 | 02:05h | UTC

Long-Term Drug Therapy and Drug Discontinuations and Holidays for Osteoporosis Fracture Prevention: A Systematic Review – Annals of Internal Medicine (free)

See also: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review – Agency for Healthcare Research and Quality (free) AND Full Report (free PDF) AND Evidence Summary (free PDF)

 


JAMA Guideline Synopsis: Colorectal Cancer Screening

26 Apr, 2019 | 01:55h | UTC

Colorectal Cancer Screening – JAMA (free for a limited period)

Related: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)

 


Sitting Time, Physical Activity, and Risk of Mortality in Adults

26 Apr, 2019 | 01:54h | UTC

Sitting Time, Physical Activity, and Risk of Mortality in Adults – Journal of the American College of Cardiology (free)

Commentaries: How much do sedentary people really need to move? It’s less than you think – The Conversation (free) AND Physical Activity May Offset Mortality Risk Caused by Too Much Sitting – American College of Cardiology (free) AND Sitting Kills, in a Dose-Response Fashion, but Regular Physical Activity Attenuates Risks – TCTMD (free) AND Computers, not TV, are to blame for increase in US sitting time, study says – CNN (free)

 


Consensus Paper: Diagnosing and Treating Antiphospholipid Syndrome

25 Apr, 2019 | 06:46h | UTC

Diagnosing and treating antiphospholipid syndrome: a consensus paper – The Netherlands Journal of Medicine (free PDF)

Related: Guidelines on the investigation and management of antiphospholipid syndrome – British Journal of Haematology (free)

 


Randomized Trial: Switching to Oral Antibiotics Early for Bone and Joint Infections

25 Apr, 2019 | 06:20h | UTC

Switching to oral antibiotics early for bone and joint infections gave similar results to continuing intravenous therapy – NIHR Signal (free)

Original Research: Oral versus Intravenous Antibiotics for Bone and Joint Infection (link to abstract and commentaries)

 


USPSTF Draft Statement: Screening for Asymptomatic Bacteriuria in Adults

24 Apr, 2019 | 06:34h | UTC

Draft Recommendation Statement: Asymptomatic Bacteriuria in Adults: Screening – U.S. Preventive Services Task Force (free)

Commentary: USPSTF Eases Recommendation for Asymptomatic Bacteriuria Screening in Pregnant Women – NEJM Journal Watch (free)

 


Meta-Analysis: Effects of Intensive Blood Pressure Lowering in Patients with Type 2 Diabetes

25 Apr, 2019 | 02:02h | UTC

Effects of intensive blood pressure lowering on mortality and cardiovascular and renal outcomes in type 2 diabetic patients: A meta-analysis – PLOS One (free)

 


Study: Long-Term Weight Loss with Metformin

24 Apr, 2019 | 06:24h | UTC

Long-Term Weight Loss with Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Metformin may help patients maintain weight loss long-term – American College of Physicians (free) AND Metformin may help people at high diabetes risk to maintain weight loss – Medicine Matters (free) AND Metformin may help patients maintain long-term weight loss – 2 Minute Medicine (free)

 


Meta-Analysis: In‐hospital Mobilization Programs Associated with Reduced Length of Stay and Improvement in Physical Function

24 Apr, 2019 | 06:27h | UTC

Systematic review and meta‐analysis of experimental studies: In‐hospital mobilization for patients admitted for medical treatment – Journal of Advanced Nursing (free)

Commentary: Getting hospital patients up and moving shortens stay and improves fitness – NIHR Signal (free)

Related: Randomized Trial: Effect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization (link to abstract and commentaries)

 


Review: Hepatorenal Syndrome

24 Apr, 2019 | 06:21h | UTC

Hepatorenal Syndrome – Clinical Journal of American Society of Nephrology (free)

Related: Epidemiology, Pathophysiology, and Management of Hepatorenal Syndrome (free guidelines and reviews)

 


Position Paper: Managing and Preventing Vascular Catheter Infections

23 Apr, 2019 | 01:54h | UTC

Managing and Preventing Vascular Catheter Infections ISID Position Paper – International Journal of Infectious Diseases (free)

 


Clinical Update: Metformin in 2019

23 Apr, 2019 | 01:50h | UTC

Metformin in 2019 – JAMA (free for a limited period)

 


ECG Challenge: Pseudo–Ventricular Tachycardia, Pseudo–Atrial Fibrillation, and Pseudo–Atrial Flutter in a Patient with Parkinson Disease

23 Apr, 2019 | 01:11h | UTC

Pseudo–Ventricular Tachycardia, Pseudo–Atrial Fibrillation, and Pseudo–Atrial Flutter in a Patient with Parkinson Disease: Two’s Company, Three’s a Crowd – JAMA Internal Medicine (free for a limited period)

 


Meta-Analysis of Randomized Trials: Effects of IV Hydration on Risk of Contrast Induced Nephropathy in STEMI patients Undergoing Primary PCI

22 Apr, 2019 | 22:26h | UTC

Effects of intravenous hydration on risk of contrast induced nephropathy and in-hospital mortality in STEMI patients undergoing primary percutaneous coronary intervention: a systematic review and meta-analysis of randomized controlled trials – BMC Cardiovascular Disorders (free)

 


Perspective: Shared Decision Making and the Importance of Time

22 Apr, 2019 | 02:18h | UTC

Shared Decision Making and the Importance of Time – JAMA (free for a limited period)

 


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