Internal Medicine
Randomized Trial: Restarting Antiplatelet Therapy Safe after Intracerebral Hemorrhage
23 May, 2019 | 08:05h | UTCCommentaries: Restarting antiplatelet therapy after intracerebral haemorrhage – The Lancet (free) AND Aspirin unlikely to cause more brain bleeds for stroke patients – UPI (free) AND Aspirin green light for brain bleed stroke patients, study suggests – University of Edinburgh (free)
“The risk of recurrent intracerebral hemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention.”
Mexican Consensus on the Prevention, Diagnosis, and Treatment of Clostridium Difficile Infection
23 May, 2019 | 07:57h | UTCRelated Guidelines: IDSA Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children (free) AND 2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients – World Journal of Emergency Surgery (free) AND The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications (free) AND Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients (free) AND Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children (free)
Alex Nowbar’s Journal Reviews—22 May 2019
23 May, 2019 | 07:49h | UTCAlex Nowbar’s journal reviews, 22 May 2019 – The BMJ Opinion (free)
Evidence‐based Diabetes Care for Older People with Type 2 Diabetes
23 May, 2019 | 07:47h | UTC
Choosing Wisely Canada-Top Five List in Hepatology
23 May, 2019 | 07:44h | UTCSee complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
1 – Don’t order serum ammonia to diagnose or manage hepatic encephalopathy (HE).
2 – Don’t routinely transfuse fresh frozen plasma, platelets or give Vitamin K to reverse abnormal tests of coagulation in patients with cirrhosis prior to abdominal paracentesis, endoscopic variceal band ligation, or any other minor invasive procedures.
3 – Don’t order HFE genotyping based on serum ferritin values alone to diagnose hereditary hemochromatosis.
4 – Don’t perform computed tomography (CT) or magnetic resonance imaging (MRI) routinely to monitor benign focal liver lesions (ex. focal nodal hyperplasia, hemangioma).
5 – Don’t repeat hepatitis C viral load testing in an individual who has established chronic infection, outside of antiviral treatment.
(Under a Creative Commons license)
Systematic Review: Galactomannan Detection in Broncho‐alveolar Lavage Fluid for Invasive Aspergillosis in Immunocompromised Patients
22 May, 2019 | 06:11h | UTCGalactomannan detection in broncho‐alveolar lavage fluid for invasive aspergillosis in immunocompromised patients – Cochrane Library (free)
Summary: Measuring galactomannan in lung-washing fluid to diagnose invasive aspergillosis in patients with an impaired immune system – Cochrane Library (free)
Systematic Review: Mucolytic Agents for Chronic Bronchitis or Chronic Obstructive Pulmonary Disease
22 May, 2019 | 06:16h | UTCMucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease – Cochrane Library (free)
Summary: Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease – Cochrane Library (free)
Current Concepts in Acute Liver Failure
22 May, 2019 | 06:00h | UTCCurrent concepts in acute liver failure – Annals of Hepatology (free)
Update in Surveillance Recommendations in Individuals with Conventional Adenomas
22 May, 2019 | 06:02h | UTC
Editorial: What’s New in Oxygen therapy?
22 May, 2019 | 05:57h | UTCWhat’s new in oxygen therapy? – Intensive Care Medicine (free)
Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Review: Oxygen Treatment in Intensive Care and Emergency Medicine (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)
Source: Critical Care Reviews Newsletter
A Review of Novel Antidepressants: A Guide for Clinicians
21 May, 2019 | 14:56h | UTCA Review of Novel Antidepressants: A Guide for Clinicians – Cureus (free)
#ATS2019 – Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma
21 May, 2019 | 06:16h | UTCControlled Trial of Budesonide–Formoterol as Needed for Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Treatment Changes for Mild Asthma? – NEJM Journal Watch (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – Randomized Trial: Patients with Mild Asma and Low Sputum Eosinophil Levels Do Not Benefit from Inhaled Corticosteroids
21 May, 2019 | 06:15h | UTCMometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Large portion of patients with mild persistent asthma and low sputum eosinophils respond equally well to inhaled corticosteroids as placebo – NIH News Releases (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
Viewpoint – “Millions Take Gabapentin for Pain. But There’s Scant Evidence It Works.”
21 May, 2019 | 06:04h | UTCMillions Take Gabapentin for Pain. But There’s Scant Evidence It Works. – The New York Times (10 articles per month are free)
Related: Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free) AND Benefits and safety of gabapentinoids in chronic low back pain (free) AND Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs (link to abstract)
Blood Pressure and the New ACC/AHA Hypertension Guidelines
20 May, 2019 | 17:09h | UTCBlood Pressure and the New ACC/AHA Hypertension Guidelines – Trends in Cardiovascular Medicine (free)
Original Guideline: 2017 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (free)
Related: 2018 ESC/ESH Guidelines for the management of arterial hypertension – European Heart Journal (free) AND What’s New in the ESC 2018 Guidelines for Arterial hypertension: The Ten Most Important Messages (free) AND AAFP Decides to Not Endorse AHA/ACC Hypertension Guideline – American Academy of Family Physicians (free) AND Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Synopsis of the 2017 American College of Cardiology/American Heart Association Hypertension Guideline – Annals of Internal Medicine (free) AND Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children – Canadian Journal of Cardiology (free)
Podcast: Best Practices Update and the Future of Heart Failure with Preserved EF
20 May, 2019 | 22:22h | UTCBest practices update and the future of heart failure with preserved EF – The Curbsiders Internal Medicine Podcast (free audio and summary)
Review: New-onset Atrial Fibrillation in Adult Critically Ill Patients
19 May, 2019 | 22:27h | UTCNew-onset atrial fibrillation in adult critically ill patients: a scoping review – Intensive Care Medicine (free) (via @AndersPerner)
EULAR Recommendations for the Management of Antiphospholipid Syndrome in Adults
19 May, 2019 | 22:33h | UTCRelated: Diagnosing and treating antiphospholipid syndrome: a consensus paper – The Netherlands Journal of Medicine (free PDF) AND Guidelines on the investigation and management of antiphospholipid syndrome – British Journal of Haematology (free)
Clinical Update: Management of Hepatitis C in 2019
19 May, 2019 | 22:23h | UTCManagement of Hepatitis C in 2019 – JAMA (free for a limited period)
Evaluation of the Solitary Pulmonary Nodule
19 May, 2019 | 21:47h | UTCEvaluation of the Solitary Pulmonary Nodule – Internal Medicine Journal (free)
Related: Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017 – Radiology (free) AND Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (free) AND British Thoracic Society guidelines for the investigation and management of pulmonary nodules (free) AND Management pathways for solitary pulmonary nodules – Journal of Thoracic Disease (free)
Meta-Analysis: Perioperative/Postoperative Atrial Fibrillation and Risk of Subsequent Stroke and/or Mortality
19 May, 2019 | 21:15h | UTCPerioperative/Postoperative Atrial Fibrillation and Risk of Subsequent Stroke and/or Mortality – Stroke (link to abstract – $ for full-text)
Commentary: Perioperative Atrial Fibrillation and Risk of Stroke, Mortality – American College of Cardiology (free)
Early Repolarization Syndrome: Diagnostic and Therapeutic Approach
19 May, 2019 | 21:05h | UTC
Cohort Study: Hypoglycemia at Hospital Discharge Linked to Poor Outcomes in Diabetics
19 May, 2019 | 14:42h | UTCAssociation of glucose concentrations at hospital discharge with readmissions and mortality: A nationwide cohort study. – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Hypoglycemia at End of Hospital Stay Linked to Readmission, Mortality in Diabetes – Endocrinology Advisor (free) AND Hypoglycemia on the day of hospital discharge linked to adverse outcomes – Medicine Matters (free)
Two Studies Point to Increase in Colorectal Cancer Incidence in Young Adults
19 May, 2019 | 13:27h | UTCChanges in colorectal cancer incidence in seven high-income countries: a population-based study – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Related Research: Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years – Gut (link to abstract – $ for full-text)
Commentaries: Bowel cancer rates rising ‘among young adults’ – BBC (free) AND Expert reaction to two studies on the rise of bowel cancer among young adults – Science Media Centre (free) AND Colorectal cancer is killing more 20- to 30-year-olds. We have some clues about why. – VOX (free)
Anticoagulation in Chronic Kidney Disease: From Guidelines to Clinical Practice
19 May, 2019 | 13:00h | UTC