Internal Medicine
The ABCs of Primary Cardiovascular Prevention: 2019 Update
31 May, 2019 | 08:35h | UTCThe ABCs of Primary Cardiovascular Prevention: 2019 Update – American College of Cardiology (free) (via @paomorejon)
Original Guideline: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease (free guideline and related resources)
Cohort Study: Use of Proton Pump Inhibitors Associated with Increased Mortality
31 May, 2019 | 06:28h | UTCCommentaries: Investigating the causes of death attributable to use of proton pump inhibitors – The BMJ Opinion (free) AND Heartburn drugs linked to fatal heart and kidney disease, stomach cancer – Washington University in St. Louis (free) AND Overuse of heartburn drugs linked to heart, kidney disease, cancer – UPI (free) AND Proton-pump inhibitors (PPIs) Linked to Increased Risk of Death – MedicalResearch.com (free)
Antidepressants and Weight Gain: Long-term Population Impact
31 May, 2019 | 05:12h | UTCAntidepressants and weight gain: long-term population impact #SUSANAsurvey – The Mental Elf (free)
Original Study: Cohort Study: Weight Gain with Antidepressant Utilization (free study and commentaries)
Systematic Review: Tramadol for Osteoarthritis
30 May, 2019 | 08:28h | UTCTramadol for osteoarthritis – Cochrane Library (free)
Summary: Tramadol for osteoarthritis – Cochrane Library (free)
“tramadol alone or in combination with acetaminophen probably has no important benefit on mean pain or function in people with osteoarthritis, although slightly more people in the tramadol group report an important improvement”
Alex Nowbar’s Journal Reviews—29 May 2019
30 May, 2019 | 08:20h | UTCAlex Nowbar’s journal reviews, 29 May 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Societies Issue Statement Against New Treatment Recommendations for Subclinical Hypothyroidism
30 May, 2019 | 08:18h | UTCOriginal Article: BMJ Guideline: Treatment of Subclinical Hypothyroidism (free)
Short Review: Interpreting Pleural Fluid Results
29 May, 2019 | 10:40h | UTCInterpreting pleural fluid results – Clinical Medicine (free)
Source: Critical Care Reviews Newsletter
Another Study Supports Nonfasting Measurement of Lipid Levels
29 May, 2019 | 02:02h | UTCAssociation of Nonfasting vs Fasting Lipid Levels With Risk of Major Coronary Events in the Anglo-Scandinavian Cardiac Outcomes Trial–Lipid Lowering Arm – JAMA Internal Medicine (free for a limited period)
Commentaries: New evidence: It’s not necessary to fast before complete cholesterol test – Brigham and Women’s Hospital (free) AND More Evidence That Fasting Isn’t Necessary Before Lipid Tests – NEJM Journal Watch (free)
Study: Fall-related Injuries are a Leading Hospital Readmission Diagnosis
29 May, 2019 | 01:39h | UTCPosthospital Fall Injuries and 30-Day Readmissions in Adults 65 Years and Older – JAMA Network Open (free)
Commentaries: Hospitals fall short in teaching fall prevention to departing patients – University of Michigan (free) AND Fall Injuries Top Cause of Hospital Readmission in Elderly – Medscape (free registration required)
[Abstract Only] Cohort Study: Long‐term Risk of Recurrence in Patients with a First Unprovoked Venous Thromboembolism Managed According to D‐dimer Results
28 May, 2019 | 10:33h | UTCLong‐term risk of recurrence in patients with a first unprovoked venous thromboembolism managed according to d‐dimer results; A cohort study – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)
Commentary: VTE Recurrence After Negative D-Dimer Testing – Journal Watch (free)
A Safety Update on Sodium Glucose Co‐transporter 2 Inhibitors
28 May, 2019 | 10:32h | UTCA safety update on sodium glucose co‐transporter 2 inhibitors – Diabetes, Obesity and Metabolism (free)
Synopsis of the 2018 AHA/ACC Cholesterol Clinical Practice Guidelines
28 May, 2019 | 01:24h | UTCOriginal Guideline: New AHA/ACC Guideline on the Management of Blood Cholesterol (free guideline and resources)
Inpatient Management of Acute Severe Ulcerative Colitis
28 May, 2019 | 00:59h | UTCInpatient Management of Acute Severe Ulcerative Colitis – Journal of Hospital Medicine (free PDF via Unpaywall)
Source: Hospital Medicine Virtual Journal Club
Meta-Analysis of Delirium Preventive Models of Care
28 May, 2019 | 00:55h | UTCPreventing Delirium Takes a Village: Systematic Review and Meta-Analysis of Delirium Preventive Models of Care – Journal of Hospital Medicine (free PDF via Unpaywall)
Source: Hospital Medicine Virtual Journal Club
JACC Review: Deprescribing in Older Adults with Cardiovascular Disease
26 May, 2019 | 20:18h | UTCDeprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology (free for a limited period)
Related: Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
Related Commentary on Twitter
Deprescribing in Older Adults With Cardiovascular Disease
– its hard, it takes time, but it is probably as important as prescribing!#Cardiology #Cardiotwitter #publichealth https://t.co/1urlIi61RD pic.twitter.com/hOXUlZ5M7u
— Konstantin Krychtiuk (@krychtiukmd) May 25, 2019
[Abstract Only] Randomized Trial: Gentamicin vs. Ceftriaxone for the Treatment of Gonorrhea
28 May, 2019 | 00:51h | UTCGentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Clinical trial finds gentamicin inferior to ceftriaxone for gonorrhea – CIDRAP (free) AND Drug combination could be effective for treatment resistant gonorrhea – NIHR (free) AND New drug combination could be effective for treatment-resistant gonorrhea – OnMedica (free) AND Quick Take: Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG) – 2 Minute Medicine (free)
Guideline: Change in Renal Function Associated with Drug Treatment in Heart Failure
26 May, 2019 | 20:16h | UTCChange in renal function associated with drug treatment in heart failure: national guidance – Heart (free)
Randomized Trial: Daily Self‐Weighing May Prevent Holiday‐Associated Weight Gain
26 May, 2019 | 20:10h | UTCDaily Self‐Weighing to Prevent Holiday‐Associated Weight Gain in Adults – Obesity (free)
Commentaries: Daily self-weighing can prevent holiday weight gain – University of Georgia (free) AND Researchers reveal new strategy for preventing holiday weight gain – The Obesity Society (free) AND Weighing yourself every day could prevent weight gain – Medical News Today (free)
Position Paper: Management of Hyperkalemia in Patients with kidney disease
26 May, 2019 | 12:46h | UTC
Review: Evaluation and Management of Acute Pancreatitis
25 May, 2019 | 12:02h | UTCEvaluation and management of acute pancreatitis – World Journal of Clinical Cases (free)
Related Guidelines: American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)
[Abstract Only] Randomized Trial: Patients with COPD Exacerbation and Low Eosinophil Count May be Treated with Shorter Corticosteroid Treatment
24 May, 2019 | 05:19h | UTCEosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary: 2 Minute Medicine Rewind May 20, 2019 (4th Summary)
See also: Video Summary – Medwire News (free audio)
Related Commentary on Twitter
Presenting now at #ATS2019 @atscommunity—Eosinophil-guided corticosteroid therapy in patients admitted to hospital with #COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial https://t.co/YqUlX54gc5 pic.twitter.com/Bw1n9Tuink
— The Lancet Respiratory Medicine (@LancetRespirMed) May 20, 2019
Strategies to Relieve Dyspnea in Patients with Advanced Chronic Respiratory Diseases
24 May, 2019 | 05:16h | UTC
May Measurement Month 2018: A Pragmatic Global Screening Campaign to Raise Awareness of Hypertension
24 May, 2019 | 05:24h | UTCCommentary: Only a third of people have hypertension under control – OnMedica (free)
Neutrophil-Lymphocyte Ratio (NLR): Free Upgrade to your WBC
24 May, 2019 | 05:14h | UTCNeutrophil-Lymphocyte Ratio (NLR): Free upgrade to your WBC – PulmCrit (free)
Treatment of Infections Due to MDR Gram-Negative Bacteria
23 May, 2019 | 12:26h | UTCTreatment of Infections Due to MDR Gram-Negative Bacteria – Frontiers in Medicine (free)


