Internal Medicine
Urinary Tract Infections Affect Millions. The Cures Are Faltering.
14 Jul, 2019 | 19:49h | UTCUrinary Tract Infections Affect Millions. The Cures Are Faltering. – The New York Times (10 articles per month are free)
“As the infections become increasingly resistant to antibiotics, some standard treatments no longer work for an ailment that was once easily cured.”
A Current Appraisal of Evidence for the Approach to Sepsis and Septic Shock
14 Jul, 2019 | 19:43h | UTCSource: Critical Care Reviews Newsletter
[Abstract Only] Meta-Analysis: Balanced Crystalloids Do Not Improve Outcomes When Compared with Normal Saline in Critically Ill Patients
14 Jul, 2019 | 19:13h | UTCChoice of Intravenous Crystalloid Fluid and Mortality in Critically Ill Adult Patients – Southern Medical Journal (link to abstract – $ for full-text)
Related Randomized Trials: Balanced Crystalloids vs Saline in Hospitalized Patients (free studies and commentary)
Source: Hospital Medicine Virtual Journal Club
[Abstract Only] Randomized Trial: PPI, H2RA Equally Effective for Prevention of Recurrent Idiopathic Gastroduodenal Ulcer Bleeding
14 Jul, 2019 | 19:03h | UTCPrevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial – Gut (link to abstract – $ for full-text)
Commentary: PPI, H2RA Equally Good at Preventing Bleeding Recurrence in H. Pylori-Negative Ulcers – Medscape (free registration required)
Study: Diagnosis Errors Account for One-third of Severe Harm Malpractice Claims
12 Jul, 2019 | 08:05h | UTCSerious misdiagnosis-related harms in malpractice claims: The “Big Three” – vascular events, infections, and cancers – Diagnosis (free)
Commentary: Diagnosis errors account for one-third of severe harm malpractice claims – Modern Healthcare (free) AND Study: 100k patients injured, die each year after misdiagnosis – UPI (free)
Related Report: Improving Diagnosis in Health Care – The National Academies of Sciences Engineering and Medicine (free)
Interventions to Treat Erectile Dysfunction and Premature Ejaculation: An Overview of Systematic Reviews
12 Jul, 2019 | 07:54h | UTCRelated Guidelines: Erectile Dysfunction: AUA Guideline (free) AND An Update of the International Society of Sexual Medicine’s Guidelines for the Diagnosis and Treatment of Premature Ejaculation – Sexual Medicine (free)
[Abstract Only] Study: The Benefits of Clopidogrel-aspirin Combination after Minor Stroke/TIA occurs Predominantly Within the First 21 Days
12 Jul, 2019 | 08:03h | UTCTime Course for Benefit and Risk of Clopidogrel and Aspirin after Acute Transient Ischemic Attack and Minor Ischemic Stroke: A Secondary Analysis from the POINT Randomized Trial – Circulation (link to abstract – $ for full-text)
Commentary: Clopidogrel-Aspirin in Minor Stroke/TIA of Maximum Benefit in First 21 Days – TCTMD (free)
Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)
Viewpoint: Preclinical Alzheimer Disease—Early Diagnosis or Overdiagnosis?
12 Jul, 2019 | 07:52h | UTCPreclinical Alzheimer Disease—Early Diagnosis or Overdiagnosis? – JAMA Internal Medicine (free for a limited period)
Related Commentary on Twitter
Preclinical #AlzheimerDisease: may identify high-risk group to target new preventive medications, but may also lead to overdiagnosis and high costs https://t.co/GK3soETwd1
— JAMA Internal Medicine (@JAMAInternalMed) July 9, 2019
[Abstract Only] Meta-analysis: Association Between Blood Pressure Variability, Cardiovascular Disease and Mortality In Type 2 Diabetes
12 Jul, 2019 | 07:45h | UTCAssociation Between Blood Pressure Variability, Cardiovascular Disease And Mortality In Type 2 Diabetes: A Systematic Review And Meta‐Analysis – Diabetes, Obesity and Metabolism (link to abstract – $ for full-text)
Commentary: Systolic BP variability associated with increased risk of death, CV events in patients with type 2 diabetes, meta-analysis finds – ACP Diabetes (free)
Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries
11 Jul, 2019 | 11:08h | UTCEditorial: Myocardial Infarction With Nonobstructive Coronary Arteries: A Call for Individualized Treatment (free)
Related: Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association (free) AND The What, When, Who, Why, How and Where of Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA) – Circulation Journal (free) AND Systematic Review of Patients Presenting With Suspected Myocardial Infarction and Nonobstructive Coronary Arteries – Circulation (free) AND Nonobstructive Versus Obstructive Coronary Artery Disease in Acute Coronary Syndrome: A Meta‐Analysis – Journal of the American Heart Association (free)
“Patients with MINOCA and those with myocardial infarction with obstructive coronary artery disease had comparable clinical outcomes. Use of renin‐angiotensin system blockers and statins was associated with lower mortality in patients with MINOCA.”
[Abstract Only] Randomized Trial: C-Reactive Protein Can Guide Antibiotics for COPD Exacerbations
11 Jul, 2019 | 11:18h | UTCC-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: CRP Testing Can Safely Reduce Antibiotic Use for COPD Exacerbations – NEJM Journal Watch (free) AND Fingerprick Biomarker Test Can Reduce Use of Antibiotics in COPD Flares – MedicalResearch.com (free)
Drug-induced Endocrinopathies and Diabetes
11 Jul, 2019 | 10:27h | UTC
Cohort Study: Microvascular Disease, Peripheral Artery Disease and Amputation
11 Jul, 2019 | 10:33h | UTCMicrovascular Disease, Peripheral Artery Disease and Amputation – Circulation (free PDF)
Commentaries: Microvascular Disease Quadruples Risk of Leg Amputation – TCTMD (free) AND Microvascular Disease Anywhere in the Body May Be Linked to Higher Risk of Leg Amputations – American Heart Association (free)
Quality Improvement Goals for Acute Kidney Injury
11 Jul, 2019 | 10:15h | UTC
Related Commentary on Twitter
Quality Improvement Goals for Acute Kidney Injury: "The AKI care process starts with the community, continues in the hospital, and ends in community, and each of these phases requires specific intervention." https://t.co/V4nkKQLZuL #FridayReads #ICYMI #AKI
— Crit Care Nephrology (@CCCNPitt) May 24, 2019
Pathophysiology and Management of Diabetic Gastroenteropathy
11 Jul, 2019 | 10:21h | UTC
Ann Robinson’s journal review—10 July 2019
11 Jul, 2019 | 09:59h | UTCAnn Robinson’s journal review, 10 July 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
[Abstract Only] Randomized Trial: Selective Referral Using CCTA First vs. Direct Referral for Individuals with Indication of Invasive Coronary Angiography for Suspected CAD
10 Jul, 2019 | 09:50h | UTCSelective Referral Using CCTA Versus Direct Referral for Individuals Referred to Invasive Coronary Angiography for Suspected CAD: A Randomized, Controlled, Open-Label Trial – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)
Commentary: Coronary Computed Tomographic Angiography for Selective Cardiac Catheterization – CONSERVE – American College of Cardiology (free)
Review: Subclinical Hypothyroidism
10 Jul, 2019 | 02:36h | UTCSubclinical Hypothyroidism – A Review – JAMA (free link for a limited period)
Related: BMJ Guideline: Treatment of Subclinical Hypothyroidism (free guideline and commentaries)
Review: Management of Acute Variceal Hemorrhage
10 Jul, 2019 | 02:31h | UTCManagement of acute variceal hemorrhage – F1000Research (free)
Review: Evaluating and Managing Bradycardia
10 Jul, 2019 | 02:32h | UTCEvaluating and Managing Bradycardia – Trends in Cardiovascular Medicine (free)
Related: 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay (free guideline and resources)
ERS Statement on Chest Imaging in Acute Respiratory Failure
9 Jul, 2019 | 10:26h | UTCERS statement on chest imaging in acute respiratory failure – European Respiratory Journal (free PDF)
Guidelines on the Diagnosis and Management of Patients at Risk of Gastric Adenocarcinoma
9 Jul, 2019 | 10:30h | UTC
[Abstract Only] Little Evidence for Nutritional Supplements to Improve Cardiovascular Outcomes
9 Jul, 2019 | 10:19h | UTCEffects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Little evidence supports nutritional supplements for protection against cardiovascular disease, death – ACP Internist (free) AND Nutritional supplements and diets not always protective, WVU research suggests – West Virginia University (free) AND Supplements and Diets for Heart Health Show Limited Proof of Benefit – The New York Times (10 articles per month are free)
Related Study: Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free) AND Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)
Podcast: Atrial Fibrillation Review and Update
9 Jul, 2019 | 10:06h | UTC#159 Atrial Fibrillation Review and Update – The Curbsiders Internal Medicine Podcast (free audio and summary)
[Abstract Only] Cohort Study: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized with Pneumonia
9 Jul, 2019 | 10:13h | UTCExcess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Pneumonia patients get too many antibiotics – especially as they leave the hospital – University of Michigan (free)
Related Commentary on Twitter
https://twitter.com/ABsteward/status/1148384237499899904