Internal Medicine
Ann Robinson’s journal review—7 November 2019
8 Nov, 2019 | 07:15h | UTCAnn Robinson’s journal review, 7 November 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
[Abstract Only] Study: Evidence of Bacterial Transmission from Probiotic Capsule to Blood in ICU Patients
8 Nov, 2019 | 07:36h | UTCGenomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients – Nature Medicine (link to abstract – $ for full-text)
Related: Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries) AND The Problem With Probiotics – The New York Times (free)
Related Commentary on Twitter
The use of #probiotics in hospitals is increasing. Now the first proof via genomic sequencing that these pills can induce sepsis https://t.co/mY0gxPXFQ1 @NatureMedicine by @TechnionLive's @idanyelin @harvardmed and collaborators pic.twitter.com/GZ6HgwxWyR
— Eric Topol (@EricTopol) November 7, 2019
Insomnia Symptoms and Risk of Cardiovascular Diseases Among 0.5 Million Adults: A 10-year Cohort
8 Nov, 2019 | 07:11h | UTCCommentaries: Difficulty sleeping linked with raised risk of heart attack and stroke – NHS Choices (free) AND Insomnia in adults linked to heart attack and stroke – CNN (free) AND Insomnia maybe a significant risk factor for heart attacks and strokes – News Medical (free)
[Abstract Only] Another Study Questions the Association of Contrast Use and Acute Kidney Injury
7 Nov, 2019 | 08:03h | UTCAssociation of contrast and acute kidney injury in the critically ill: A propensity matched study – CHEST (link to abstract – $ for full-text)
Commentary: No association between contrast use and AKI seen in critically ill patients with normal kidney function – ACP Hospitalist (free)
Related: Does contrast cause kidney injury? The evidence – First10EM (free) AND Are the Risks Of Drugs That Enhance Imaging Tests Overblown? – NPR (free) AND Acute Kidney Injury After Computed Tomography: A Meta-analysis – Annals of Emergency Medicine (link to abstract – $ for full-text) AND Risk of Acute Kidney Injury After Intravenous Contrast Media Administration – Annals of Emergency Medicine (link to abstract – $ for full-text) AND
Study: Association Between Gifts from Pharmaceutical Companies to Doctors and Their Drug Prescribing Patterns
7 Nov, 2019 | 08:07h | UTC
Related Commentary on Twitter
New study shows that gifts to GPs are common and associated with less rational drug prescriptions for patients and more expenses for the National Health Insurance https://t.co/Hvu6BqrHhi
— The BMJ (@bmj_latest) November 6, 2019
Cohort Study: Metformin Use Linked to Lower Risk of Hospitalization for Heart Failure in Patients with Type 2 Diabetes
7 Nov, 2019 | 07:40h | UTCCommentary: Metformin lowers risk of HF hospitalization in those with T2D – Cardiovascular Business (free)
Related Study: Metformin Use Linked to Reduced Risk for Cardiovascular Death and All-cause Mortality (link to abstract and commentaries)
Update on the Management of Constipation
7 Nov, 2019 | 07:35h | UTCUpdate on the Management of Constipation – JAMA (free for a limited period)
Related: Indian Consensus on Chronic Constipation in Adults (free guidelines and reviews on the subject)
Guidelines on Long-term Home Non-invasive Ventilation for Management of COPD
4 Nov, 2019 | 01:26h | UTCSource: EvidenceAlerts
Randomized Trial: Internet Based Vestibular Rehabilitation for Adults with a Chronic Vestibular Syndrome
6 Nov, 2019 | 08:35h | UTCCommentaries: Treat dizziness and vertigo with vestibular rehabilitation – The BMJ Opinion (free) AND Online Intervention Could Help Those with Chronic Vestibular Syndrome – NEJM Journal Watch (free)
Related Study: Internet-Based Vestibular Rehabilitation for Older Adults With Chronic Dizziness (free study and commentaries)
State of the Art Review: Benefits and Harms of Intensive Glycemic Control in Patients with Type 2 Diabetes
6 Nov, 2019 | 08:37h | UTCBenefits and harms of intensive glycemic control in patients with type 2 diabetes – The BMJ (free for a limited period)
Related Commentary on Twitter
Evidence over the past decade has shown that the aggressive efforts often needed to achieve low HbA1c levels can lead to worse clinical outcomes. This review provides a summary of the evidence on the benefits and harms of intensive glycemic control https://t.co/rghp5iVRfX
— The BMJ (@bmj_latest) November 5, 2019
[Abstract Only] Cohort Study: Fecal Microbiota Transplantation Associated with Improved Outcomes in Patients with Clostridium Difficile Infection
6 Nov, 2019 | 08:33h | UTCIncidence of Bloodstream Infections, Length of Hospital Stay, and Survival in Patients With Recurrent Clostridioides difficile Infection Treated With Fecal Microbiota Transplantation or Antibiotics: A Prospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Study: Fecal Transplants Cut Sepsis Risk in Patients With C. Diff – MedPage Today (free registration required)
Related: Clostridioides Difficile: Diagnosis and Treatments (free guidelines and reviews)
Meta-Analysis: Mind-Body Therapies for Opioid-Treated Pain
6 Nov, 2019 | 08:10h | UTCMind-Body Therapies for Opioid-Treated Pain: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Commentaries: Study highlights role of mind-body therapies in addressing opioid-treated pain – News Medical (free) AND Meditation, Mindfulness Hold Promise for Pain Treatment, Curbing Opioid Use – U.S. News (free)
Consensus Document: Follow-up of Patients after Revascularization for Peripheral Arterial Diseases
5 Nov, 2019 | 10:20h | UTC
Podcast: Random Pearls in Pulmonary Medicine and Critical Care from #CHEST2019 in New Orleans
5 Nov, 2019 | 08:39h | UTC#179 CHEST 2019 Recap Part 1 – The Curbsiders Internal Medicine Podcast (free audio)
#180 CHEST 2019 Recap Part 2 from New Orleans – The Curbsiders Internal Medicine Podcast (free audio)
ACP Guideline: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults
5 Nov, 2019 | 10:43h | UTCNews Release: ACP issues guidance for colorectal cancer screening – American College of Physicians (free)
Summaries for Patients: Colorectal Cancer Screening in Average-Risk Adults (free)
Commentaries: ACP issues new guidance on colorectal cancer screening – ACP Internist (free) AND Medical groups differ on when to start colon and rectal cancer screening. Here’s why – CNN (free)
Related: BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy (new guideline suggesting a more selective approach to screening) AND Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society (recent guideline with recommendation to start screening at 45 years, with links to guidelines from other organizations)
A Systematic Review of Guidelines for Managing Rheumatoid Arthritis
5 Nov, 2019 | 08:52h | UTCA systematic review of guidelines for managing rheumatoid arthritis – BMC Rheumatology (free)
Related Guidelines: Rheumatoid arthritis in adults: management – National Institute for Health and Care Excellence (free) AND 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis (free)
Choosing Wisely in Family Medicine: Thirteen Things Physicians and Patients Should Question
5 Nov, 2019 | 08:32h | UTCThirteen Things Physicians and Patients Should Question – Choosing Wisely Canada (free)
Related: American Academy of Family Physicians: Twenty Things Physicians and Patients Should Question (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
[Abstract Only] Meta-Analysis: Fish Oil Supplements Have no Effect on Anxiety and Depression
5 Nov, 2019 | 08:13h | UTCOmega-3 and polyunsaturated fat for prevention of depression and anxiety symptoms: systematic review and meta-analysis of randomised trials – British Journal of Psychiatry (link to abstract – $ for full-text)
News Release: Fish oil supplements have no effect on anxiety and depression – University of East Anglia (free)
Perspective – Correlation Confounded by Timing: One Reason we Believe Bad Therapies are Awesome
5 Nov, 2019 | 08:29h | UTCCorrelation confounded by timing: One reason we believe bad therapies are awesome – PulmCrit (free)
Systematic Review: Intra‐pleural Fibrinolytic Therapy for the Treatment of Parapneumonic Effusions and Empyema
31 Oct, 2019 | 08:18h | UTCIntra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult parapneumonic effusions and empyema – Cochrane Library (free)
Summary: Clot-busting drugs for infections of the lining of the lung – Cochrane Library (free)
EULAR Recommendations for the Management of Sjögren’s Syndrome
4 Nov, 2019 | 01:23h | UTCRelated Guideline: The British Society for Rheumatology guideline for the management of adults with primary Sjögren’s Syndrome – Rheumatology (free)
Meta-Analysis: Which Modes of Exercise are Most Effective for Treating Low Back Pain?
4 Nov, 2019 | 01:19h | UTC
Related Commentary on Twitter
Hot off the press 🔥🔓🔥
Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis
👀👀👇👇https://t.co/MTLlPbew6Z pic.twitter.com/wiOK4ukyig
— Physio Meets Science (@PhysioMeScience) October 30, 2019
Randomized Trial: Naproxen vs. Colchicine for the Treatment of Gout Flares in Primary Care
4 Nov, 2019 | 01:13h | UTC
Related Commentary on Twitter
Our @NIHRSPCR funded research finds no diff in pain between people with a #goutflare randomised to either #naproxen or low-dose #colchicine, but #naproxen caused fewer #sideeffects, supporting its use as first-line treatment for #flares in #primarycare https://t.co/cKBDymlFjS
— Inflam Arthr Keele (@KeeleInflamArth) November 1, 2019
Podcast: Emerging Applications for Ketamine
4 Nov, 2019 | 00:50h | UTCEmerging Applications for Ketamine – JAMA (free audio)
Related Resources:
Ketamine for Depression: Ketamine and depression: a narrative review – Drug Design, Development and Therapy (free)
Alex Nowbar’s weekly review—1 November 2019
4 Nov, 2019 | 00:41h | UTCAlex Nowbar’s weekly review, 1 November 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.