Internal Medicine
Review: Vaccines for International Travel
4 Nov, 2019 | 00:28h | UTCVaccines for International Travel – Mayo Clinic Proceedings (free)
See also: Just Released. 2020 Edition of CDC Traveler’s Health Yellow Book (free resources)
New Enhanced Recovery After Surgery (ERAS) Guideline: Perioperative Care in Total Hip Replacement and Total Knee Replacement Surgery
1 Nov, 2019 | 10:43h | UTCRelated: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)
Randomized Trial: Severe Energy Restriction Associated with Increased Bone Loss when Compared with Moderate Energy Restriction
3 Nov, 2019 | 19:48h | UTCCommentary: Total Meal Replacement Diets Effective for Weight Loss, But Can Lead To Bone Loss – MedicalResearch.com (free)
Meta-Analysis: Short- vs. Long-term Dual Antiplatelet Therapy in Secondary Prevention for Ischemic Stroke
1 Nov, 2019 | 10:24h | UTCRelated Study: Dual Antiplatelet Therapy Should be Used for 21 Days After Minor Ischemic Stroke or High-risk Transient Ischemic Attack (link to abstract)
Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)
Related Commentary on Twitter
Short-term DAPT had better risk-benefit profile than long-term DAPT in secondary prevention of ischaemic stroke – a network meta-analysis https://t.co/suoThL5GLK@escardio #EHJQCCO @adamtimmis @cpgale3 #cardiotwitter pic.twitter.com/ppzyv37Oou
— European Society of Cardiology Journals (@ESC_Journals) October 27, 2019
Meta-Analysis: Calcium Supplementation May Increase the Risk of Myocardial Infarction
1 Nov, 2019 | 07:42h | UTCRelated Meta-Analysis with Conflicting Results: Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis – Annals of Internal Medicine (free)
See also: Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures (free)
AHA/ASA Guideline Update: Early Management of Acute Ischemic Stroke
31 Oct, 2019 | 08:49h | UTCTop Things to Know: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke (free)
Study: Treatment of Subclinical Hypothyroidism Not Beneficial for Elderly Patients
31 Oct, 2019 | 08:42h | UTCAssociation Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism – JAMA (free for a limited period)
Editorial: The Thyrotropin Reference Range Should Be Changed in Older Patients (free for a limited period)
Related Review: Subclinical Hypothyroidism – JAMA (free for a limited period)
Related Randomized Trial: Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism – New England Journal of Medicine (free)
Related Commentary on Twitter
Important RCT data demonstrating that routine treatment with levothyroxine for subclinical hypothyroidism in adults aged 80 years and older was not associated with improved patient-reported quality of life outcome scores for hypothyroid symptoms https://t.co/KboKmMFcxm
— Joseph Ross (@jsross119) October 30, 2019
[Abstract Only] New Details Emerge in Case of First Death from Fecal Transplant
31 Oct, 2019 | 08:30h | UTCOriginal Article: Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant – New England Journal of Medicine ($)
Related FDA Safety Alert: Fecal Transplant May Have Caused a Patient’s Death Due to Transmission of a Multi-Drug Resistant Organism (free)
Together We Stand, Divided We Fall: A Multidisciplinary Approach in Complicated Acute Pancreatitis
30 Oct, 2019 | 07:46h | UTCRelated Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)
[Abstract Only] Cohort Study: Mortality-related Health Metrics Associated with Mental Disorders
29 Oct, 2019 | 10:33h | UTCA comprehensive analysis of mortality-related health metrics associated with mental disorders: a nationwide, register-based cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Life expectancy mapped for people with mental disorders – The University of Queensland (free) AND Mentally ill die many years earlier than others – Aarhus University (free)
Related Commentary on Twitter (Thread – Click for More)
https://twitter.com/oleguerplana/status/1187497468105089024?s=03
[Abstract Only] Meta-Analysis: Insufficient Evidence for The Use of Cannabinoids for Treating Mental Disorders
29 Oct, 2019 | 10:24h | UTCCannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentaries: Marijuana Cannabinoids Don’t Help With Depression, Anxiety, ADHS, Tourettes, Psychosis, Or PTSD – Scientific Blogging (free) AND There is little evidence that cannabis helps mental health problems – NewScientist (free) AND There’s ‘Scarce Evidence’ to Suggest Cannabis Improves Mental Health Symptoms, a New Research Review Says – TIME (free) AND Medicinal cannabis not proven in mental health, study finds – Reuters (free) AND Risks of cannabis use for mental health treatment outweigh benefits – The Guardian (free)
Related Commentary on Twitter
NEW—Insufficient evidence that medicinal #cannabinoids improve #mentalhealth: finding from a systematic review and meta-analysis combining 83 studies including 3000 people @TheLancetPsych https://t.co/dD7czOHA7O pic.twitter.com/tvsDCqcnfa
— The Lancet (@TheLancet) October 28, 2019
Analysis: Is Mycobacterium Tuberculosis Infection Life Long?
27 Oct, 2019 | 23:44h | UTCIs Mycobacterium tuberculosis infection life long? – The BMJ (free)
Commentaries: Tuberculous infection is not life-long in most people – University of Pennsylvania School of Medicine (free) AND In the absence of a true test for latent TB we need shorter, safer preventive treatments – The BMJ Opinion (free)
Related Commentary on Twitter
People with immunoreactivity to tuberculosis are thought to have lifelong asymptomatic infection and remain at risk for active tuberculosis. Is this assumption valid? Marcel A Behr and colleagues argue that most of these people are no longer infected https://t.co/LlRcMNlriJ
— The BMJ (@bmj_latest) October 27, 2019
Opinion – “Sepsis Hysteria: Excess Hype and Unrealistic Expectations”
27 Oct, 2019 | 23:49h | UTCSepsis hysteria: excess hype and unrealistic expectations – The Lancet (free)
Commentary: Sepsis myths create ‘unhealthy climate of fear’, say experts – The Guardian (free)
Source: Grupo UTIclínica – HCFMUSP
Related Commentary on Twitter
"It is crucial to expose the fictions surrounding #sepsis…to create realistic expectations about outcomes"
Sepsis hysteria: NEW Correspondence from M Singer, M Inada-Kim & M Shankar-Hari https://t.co/3oVYkE1BQS pic.twitter.com/gMvdVyCicc
— The Lancet (@TheLancet) October 25, 2019
Diagnosis and Management of Disorders of Body Tonicity—Hyponatremia and Hypernatremia
28 Oct, 2019 | 00:46h | UTCSource: Grupo UTIclínica – HCFMUSP
Things We Do for No Reason: Supplemental Oxygen for Patients without Hypoxemia
27 Oct, 2019 | 23:40h | UTCSee other articles in the series: Choosing Wisely: Things We Do For No Reason (free)
Related: Oxygen therapy for acutely ill medical patients: a clinical practice guideline – The BMJ (free) AND Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary) AND A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less? – BioMed Research International (free)
Hospital Medicine Update: High-Impact Literature from March 2018 to April 2019
27 Oct, 2019 | 23:42h | UTC
Interest in Cannabidiol Products Keeps Soaring Despite Limited Evidence in Humans
27 Oct, 2019 | 19:29h | UTCTrends in Internet Searches for Cannabidiol (CBD) in the United States – JAMA Network Open (free)
Commentaries: Interest in CBD products keeps soaring, but health experts wary – HealthDay (free) AND Online Searches For CBD Skyrocket – MedicalResearch.com (free)
Related Commentary on Twitter
"Interest in CBD products keeps soaring, but health experts wary" https://t.co/TP50a31bbP via @medical_xpress
"At this time there are no known benefits for taking CBD over-the-counter. #CBD is this generation's snake oil…"
Studies "in humans are still limited…"#CBDHype.
— Timothy Caulfield (@CaulfieldTim) October 25, 2019
Report: Safe Ambulatory Care, Strategies for Patient Safety and Risk Reduction
27 Oct, 2019 | 23:33h | UTCNews Release: ECRI Institute: Diagnostic Tests, Medication Pose Biggest Risks to Patients in Ambulatory Care (free)
Commentaries: ECRI Institute: Top 4 Biggest Risks in Ambulatory Care to Watch – HIT Consultant Media (free) AND Top 5 Patient Safety Risks in Ambulatory Care – Medscape (free registration required)
[Abstract Only] Large Observational Analysis Suggests Thiazide Diuretics are Superior as First-Line Drugs for the Treatment of Hypertension
25 Oct, 2019 | 08:48h | UTCComprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis – The Lancet (link to abstract – $ for full-text)
Commentaries: Most Prescribed Blood Pressure Drugs May Be Less Effective than Others – Columbia University Irving Medical Center (free) AND Diuretics Better Than ACE Inhibitors as Initial Hypertension Treatment, Analysis Suggests – NEJM Journal Watch (free)
Related Cochrane Review: Thiazides best first choice for hypertension (free)
Preventing Opioid Prescription After Major Surgery: A Scoping Review of Opioid-free Analgesia
25 Oct, 2019 | 08:44h | UTCRelated Review: The rising tide of opioid use and abuse: the role of the anesthesiologist – Perioperative Medicine (free)
Perspective: The Silent Heart Attack You Didn’t Know You Had
25 Oct, 2019 | 08:38h | UTCThe Silent Heart Attack You Didn’t Know You Had – The New York Times (10 articles per month are free)
Related Studies: Silent Myocardial Infarction Often Precedes Sudden Cardiac Death (link to abstract and commentaries) AND Cohort Study: Long-term Outcomes of Unrecognized MI (link to abstract and commentaries)
A State-of-the-Art Review Highlighting Medical Overuse in Dermatology, 2017-2018
24 Oct, 2019 | 08:46h | UTCA State-of-the-Art Review Highlighting Medical Overuse in Dermatology, 2017-2018: A Systematic Review – JAMA Dermatology (free for a limited period)
Review: Diagnosis and Management of Dementia
24 Oct, 2019 | 08:42h | UTCDiagnosis and Management of Dementia: Review – JAMA (free for a limited period)
The 2018 ESC/ESH Hypertension Guideline and the 2019 NICE Hypertension Guideline, How and Why they Differ
24 Oct, 2019 | 08:37h | UTCOriginal Guidelines: 2018 ESC/ESH Guidelines for the management of arterial hypertension – European Heart Journal (free) AND Hypertension in adults: diagnosis and management – National Institute for Health and Care Excellence (free)
Study Suggests Methicillin-Resistant Staphylococcus Aureus (MRSA) Acquisition and Infections are Not Impacted by use of Active Surveillance and Contact Precautions
24 Oct, 2019 | 08:14h | UTCThe effectiveness of Contact Precautions on methicillin-resistant Staphylococcus aureus (MRSA) in long-term care across the United States – Clinical Infectious Diseases (free for a limited period)
Commentary: VA study finds contact precautions don’t affect MRSA in long-term care – CIDRAP (free)