Internal Medicine
[Preprint] Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients
15 May, 2020 | 03:50h | UTCEarly Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients – medRxiv
Commentary: Convalescent plasma is safe to treat COVID-19: nationwide study – NBC News
Systematic Review: Plasma from People who Have Recovered from COVID-19 to Treat Individuals with COVID-19
15 May, 2020 | 03:48h | UTC
Study: Airborne Lifetime of Small Speech Droplets and their Potential Importance in SARS-CoV-2 Transmission
15 May, 2020 | 03:43h | UTCCommentaries: Expert reaction to study looking at speech-generated droplets and COVID-19 transmission – Science Media Centre AND Loud Talking Can Spread More than 1,000 Coronavirus Particles in the Air for 14 Minutes: Study – The Science Times AND Simply talking in confined spaces may be enough to spread the coronavirus, researchers say – USA Today AND Loud talking could leave coronavirus in the air for up to 14 minutes – MIT Technology Review
ACP Systematic Review: Chloroquine or Hydroxychloroquine Alone or in Combination with Azithromycin for the Prophylaxis or Treatment of COVID-19
15 May, 2020 | 03:32h | UTC
Study Commentary: Before/after Study of Short-Course Steroid in COVID-19
14 May, 2020 | 10:09h | UTCBefore/after study of short-course steroid in COVID-19 – PulmCrit
Original Study (Preprint): Early Short Course Corticosteroids in Hospitalized Patients with COVID-19 – medRxiv
Meta-Analysis: Manifestations and Prognosis of Gastrointestinal and Liver Involvement in COVID-19
14 May, 2020 | 10:16h | UTCRelated: Gastrointestinal, Hepatobiliary, and Pancreatic Manifestations of COVID-19 (review and guideline) AND Abdominal Imaging Findings in COVID-19: Preliminary Observations – Radiology
New Study Does Not Support the Idea that BCG Vaccination Protects Against COVID-19
14 May, 2020 | 10:12h | UTCSARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults – JAMA
Related: BCG Against Coronavirus: Less Hype And More Evidence, Please – Forbes AND Does BCG vaccination protect against acute respiratory infections and COVID-19? A rapid review of current evidence – CEBM University of Oxford AND Bacille Calmette-Guérin (BCG) vaccination and COVID-19 – World Health Organization
ERS Guideline: Withdrawal of Inhaled Corticosteroids in COPD
14 May, 2020 | 02:17h | UTC
Research Round-up: COPD
14 May, 2020 | 02:20h | UTCResearch round-up: COPD – Nature
Related: Should physicians still be prescribing steroid inhalers as a first-line treatment for COPD? – Nature AND Redefining the diagnostic criteria for COPD – Nature
See other articles from the series: Nature Outlook on COPD
Cohort Study: Pulmonary Rehabilitation Linked to Improved Survival After Hospitalization for COPD
14 May, 2020 | 02:14h | UTCAssociation Between Initiation of Pulmonary Rehabilitation After Hospitalization for COPD and 1-Year Survival Among Medicare Beneficiaries – JAMA (free for a limited period)
Editorial: Pulmonary Rehabilitation and Improved Survival for Patients With COPD (free for a limited period)
Meta-Analysis: Progression to Type 2 Diabetes in Women with Previous Gestational Diabetes
14 May, 2020 | 02:11h | UTCCommentary: Gestational diabetes—missed opportunities in post-partum follow-up – The BMJ Opinion
Interpreting a Covid-19 Test Result
13 May, 2020 | 02:18h | UTCPractice Pointer: Interpreting a covid-19 test result – The BMJ
Related: Interpreting Diagnostic Tests for SARS-CoV-2 – JAMA
Editorial: Waste in Covid-19 Research
13 May, 2020 | 02:17h | UTCWaste in covid-19 research – The BMJ
Related Landmark Paper from the Author: Avoidable waste in the production and reporting of research evidence – The Lancet (free registration required)
Related Commentary on Twitter
"A deluge of poor quality research is sabotaging an effective evidence based response" say @PaulGlasziou, Sharon Sanders and @Tammy_Hoffmann https://t.co/jvx8FQxQCo
— The BMJ (@bmj_latest) May 12, 2020
New Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19
13 May, 2020 | 02:14h | UTCSee also: Calculation Tool For Predicting Critical-ill COVID-19 At Admission
Related Preprint Study (just published): Development and validation of the COVID-19 severity index (CSI): a prognostic tool for early respiratory decompensation – medRxiv AND Calculation Tool: https://covidseverityindex.org/
Study Commentary – Virus Wars: Return of Lopinavir/Ritonavir (Along with Ribavirin and Interferon)
13 May, 2020 | 02:12h | UTCVirus Wars: Return of Lopinavir/Ritonavir (along with ribavirin and interferon) – PulmCrit
Original Article: Triple Therapy Antiviral Combination Seems Promising for COVID-19 in Open-label, Randomized, Phase 2 Trial (study and commentaries)
Gastrointestinal, Hepatobiliary, and Pancreatic Manifestations of COVID-19
13 May, 2020 | 02:05h | UTC
Hydroxychloroquine in Patients with COVID-19: A Systematic Review and Meta-analysis
13 May, 2020 | 01:53h | UTC“While initial studies with hydroxychloroquine showed some ray of hope, recent studies that have emerged found either no benefit or a possible harm in COVID-19.”
Remdesivir in COVID-19: A Critical Review of Pharmacology, Pre-clinical and Clinical Studies
13 May, 2020 | 01:50h | UTC“While the first double-blind, randomized-controlled trial (DBRCT) found no significant benefit with remdesivir compared to placebo, preliminary reports from another DBRCT showed a significant faster recovery, without any difference in mortality.”
The Dangers of Using Tumor Markers to Evaluate Nonspecific Symptoms
13 May, 2020 | 01:45h | UTCThe Dangers of Using Tumor Markers to Evaluate Nonspecific Symptoms: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
The FDA has Authorized the use of Remdesivir: But There’s no Good Evidence it Reduces Mortality in Covid-19
13 May, 2020 | 01:49h | UTC
Observational Study: Hydroxychloroquine, Azithromycin, or Both Not Associated with Lower In-hospital Mortality
12 May, 2020 | 03:39h | UTC
Abdominal Imaging Findings in COVID-19: Preliminary Observations
12 May, 2020 | 03:28h | UTCAbdominal Imaging Findings in COVID-19: Preliminary Observations – Radiology
News Release: Imaging reveals bowel abnormalities in patients with COVID-19 – Radiological Society of North America
Richard Lehman’s Covid-19 Reviews—11 May 2020
12 May, 2020 | 03:22h | UTCRichard Lehman’s Covid-19 Reviews, 11 May 2020 – The BMJ Opinion
In this weekly round-up, Richard Lehman looks at a personal selection of articles of relevance to clinicians dealing with covid-19
Coagulation Abnormalities and Thrombosis in Patients with COVID-19
12 May, 2020 | 03:16h | UTCCoagulation abnormalities and thrombosis in patients with COVID-19 – The Lancet
Related Commentary on Twitter
Good to see these welcome recommendations today for diagnosis of clotting and its prevention in patients with severe #COVID19 @TheLancetHaem https://t.co/RrtXSIu2Ne by @MarcelLevi @JerroldLevy and colleagues pic.twitter.com/dU17RIj1f2
— Eric Topol (@EricTopol) May 11, 2020
2020 ACR Guideline for the Management of Gout
12 May, 2020 | 03:14h | UTCNews Release: ACR releases gout management guideline