Internal Medicine
Case Reports: Acute Limb Ischemia in Two Young Patients with COVID-19
7 May, 2020 | 09:15h | UTCAcute limb ischaemia in two young, non-atherosclerotic patients with COVID-19 – The Lancet
Reducing Risks from Coronavirus Transmission in the Home—The Role of Viral Load
7 May, 2020 | 09:01h | UTCReducing risks from coronavirus transmission in the home—the role of viral load – The BMJ
Commentaries: Can we do more to protect people at home when a family member has coronavirus? – University of Bristol AND Coronavirus: Exposure to higher ‘viral load’ when infected could make victims more severely ill – Yahoo News
2020 International Society of Hypertension Global Hypertension Practice Guidelines
7 May, 2020 | 09:00h | UTC2020 International Society of Hypertension Global Hypertension Practice Guidelines – Hypertension
New COVID-19 Guidance for Gastroenterologists
6 May, 2020 | 03:58h | UTCNews Release: New COVID-19 guidance for gastroenterologists
COVID-19: AMA Step-by-step Guide for Physicians Planning to Reopen Medical Practices
6 May, 2020 | 04:00h | UTCCOVID-19: A physician practice guide to reopening – American Medical Association
News Release: AMA launches physician guide for reopening medical practices
Tests in Recovered Patients Found to be False Positives, Not Reinfections
6 May, 2020 | 03:48h | UTCTests in recovered patients found false positives, not reinfections, experts say – The Korea Herald
See also: Recovered patients who tested positive for COVID-19 likely not reinfected – Live Science AND South Korea says recovered coronavirus patients who tested positive again did not relapse: Tests picked up ‘dead virus fragments’ – Business Insider
Systematic Review: Chloroquine and Hydroxychloroquine as a Treatment for COVID‐19
6 May, 2020 | 03:44h | UTC“Pending further results from more extensive studies with more stringent study parameters, clinicians should defer from routine use of HCQ and CQ.”
Despite Anticoagulation, Patients with Severe SARS-CoV-2 Infection are at Increased Risk of Developing Thrombosis
6 May, 2020 | 03:40h | UTC
Perspective: Treatments Can Harm
6 May, 2020 | 03:38h | UTCTreatments can harm – Evidently Cochrane
Related: Treatments can harm – Students 4 Best Evidence (commentary and EBM resource) AND Patients’ Expectations of the Benefits and Harms of Treatments, Screening, and Tests: A Systematic Review – JAMA Internal Medicine AND If Patients Only Knew How Often Treatments Could Harm Them – The New York Times
COVID-19: Out-of-control Science and Bypassing Science-based Medicine
5 May, 2020 | 05:04h | UTCCOVID-19: Out-of-control science and bypassing science-based medicine – Science Based Medicine
Related: Covid-19 — A Reminder to Reason – New England Journal of Medicine AND Pandemic Science Out of Control – Issues in Science and Technology AND Science Has an Ugly, Complicated Dark Side. And the Coronavirus Is Bringing It Out – Mother Jones AND Against pandemic research exceptionalism – Science AND In Defense of Evidence-Based Medicine for the Treatment of COVID-19 ARDS – Annals of the American Thoracic Society
Obesity Could Shift Severe COVID-19 Disease to Younger Ages
5 May, 2020 | 04:53h | UTCObesity could shift severe COVID-19 disease to younger ages – The Lancet
NEW Correspondence—D Kass et al examined the correlation between BMI & age in 265 #COVID19 patients admitted to ICU at 6 hospitals & found a significant inverse correlation between age & BMI, in which younger individuals were more likely to be obese https://t.co/SrNSp2W7JQ pic.twitter.com/ozpBug5Mv9
— The Lancet (@TheLancet) May 1, 2020
Critical Conversations: Say This, Not That
5 May, 2020 | 04:32h | UTCCritical Conversations: Say This, Not That – CHEST
White Paper: Current Perspectives on COVID‐19 and Cardiovascular Disease
5 May, 2020 | 04:25h | UTC
[Abstract Only] Randomized Trial: No Benefit from L-thyroxine Among Elderly Patients with Symptomatic Subclinical Hypothyroidism
5 May, 2020 | 04:11h | UTCL-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: L-thyroxine did not improve symptoms or tiredness in older patients with subclinical hypothyroidism – ACP Internist AND More Evidence Against L-Thyroxine for Subclinical Hypothyroidism – NEJM Journal Watch
Related Articles: Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism – JAMA AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism – New England Journal of Medicine
Recommendations for the Management of Lower Urinary Tract Infections in Pregnant and Non-pregnant Women
5 May, 2020 | 03:57h | UTC
Systematic Review: Corticosteroids as Standalone or Add‐on Treatment for Sore Throat
5 May, 2020 | 03:36h | UTCCorticosteroids as standalone or add‐on treatment for sore throat – Cochrane Library
Summary: Corticosteroids as standalone or add‐on treatment for sore throat – Cochrane Library
New NICE Coronavirus Rapid Guidelines
3 May, 2020 | 22:46h | UTC- COVID-19 rapid guideline: antibiotics for pneumonia in adults in hospital – National Institute for Health and Care Excellence
- COVID-19 rapid guideline: gastrointestinal and liver conditions treated with drugs affecting the immune response – National Institute for Health and Care Excellence
- COVID-19 rapid guideline: children and young people who are immunocompromised – National Institute for Health and Care Excellence
See Previous NICE Coronavirus Guidelines: Rapid guidelines and evidence summaries – National Institute for Health and Care Excellence
Consensus Document: Restarting Planned Surgery in the Context of the COVID-19 Pandemic
3 May, 2020 | 22:43h | UTCRelated: New Scoring System to Prioritize Medically Necessary Operations (report and commentary)
New Observational Studies Confirm the Safety of Renin–Angiotensin–Aldosterone System Blockers in Patients with Covid-19
3 May, 2020 | 22:32h | UTCStudy 3: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19 – New England Journal of Medicine
Commentary: Blood Pressure Drugs Don’t Increase Coronavirus Risk, Studies Find – The New York Times
See also: Observational Study: Renin-Angiotensin System Inhibitors are Not Associated with Severity or Mortality in Hospitalized Patients with Coronavirus Disease (2 other studies on the subject)
Case Series: Characteristics of Ischemic Stroke Associated with COVID-19
3 May, 2020 | 22:18h | UTCCommentary: Expert reaction to study looking at COVID-19, ischaemic stroke and blood clots – Science media Centre
Related: Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young – New England Journal of Medicine AND Coronavirus’s new mystery: It’s causing strokes in healthy people – Vox AND What’s Behind the Sharp Increase in Large-Vessel Stroke Risk in Young, Healthy COVID-19 Patients? – Neurology Today
Short Review: Coagulopathy Associated with COVID-19
3 May, 2020 | 22:09h | UTCCoagulopathy associated with COVID-19 – Canadian Medical Association Journal
Case Series: QT Intervals in Patients with COVID-19 Treated with Hydroxychloroquine Alone or in Combination with Azithromycin
3 May, 2020 | 22:01h | UTCCommentary: Beth Israel Deaconess Medical Center – Beth Israel Deaconess Medical Center
Related Studies: The Effect of Chloroquine, Hydroxychloroquine and Azithromycin on the Corrected QT Interval in Patients with SARS-CoV-2 Infection – Circulation: Arrhythmia and Electrophysiology (link to abstract – $ for full-text) AND [Preprint] QT Interval Prolongation and Torsade De Pointes in Patients with COVID-19 treated with Hydroxychloroquine/Azithromycin – medRxiv
FDA Issues Emergency Use Authorization for the Use of Remdesivir to Treat COVID-19
3 May, 2020 | 22:03h | UTCSee also: Remdesivir: A Non-Antiviral Antiviral Drug? – Forbes
[Abstract Only] Meta-Analysis: Prevalence of Harmful Diagnostic Errors in Hospitalized Adults
3 May, 2020 | 21:45h | UTCPrevalence of harmful diagnostic errors in hospitalised adults: a systematic review and meta-analysis – BMJ Quality & Safety (link to abstract – $ for full-text) (via @brhospitalist)
Related Commentary on Twitter
Systematic review of 22 UK studies found that 14 common diagnoses, including malignancy and pulmonary embolism, accounted for more than half of missed or delayed diagnoses in hospital patients. @BMJ_Qual_Saf https://t.co/1JypG7idlJ pic.twitter.com/YxKeiZr5x0
— AHRQ (@AHRQNews) May 1, 2020
Classification of the Cutaneous Manifestations of COVID‐19 with 375 Illustrative Cases
1 May, 2020 | 03:43h | UTCRelated: Journal articles on coronavirus with relevance for skin diseases and dermatology – Centre of Evidence Based Dermatology, University of Nottingham AND Characterization of acute acro-ischemic lesions in non-hospitalized patients: a case series of 132 patients during the COVID-19 outbreak – Journal of the American Academy of Dermatology
Great atlas with the different cutaneous manifestations of Covid-19.