Internal Medicine
Opinion: “Get ready for vaccine false side effects”. When millions of people are vaccinated, naturally occurring health problems could be wrongly attributed to vaccines
8 Dec, 2020 | 07:55h | UTCGet Ready for False Side Effects – Science Translational Medicine
First-of-its-kind African trial tests common drugs to prevent severe COVID-19. “Could cheap, widely available drugs prevent patients with mild illness from becoming severely sick?”
8 Dec, 2020 | 07:46h | UTCFirst-of-its-kind African trial tests common drugs to prevent severe COVID-19 – Science
Observational study: Even low dose oral glucocorticoids linked to increased cardiovascular risk in people with immune-mediated inflammatory diseases
8 Dec, 2020 | 07:35h | UTCCommentary: Patients receiving low dose steroid at increased risk of cardiovascular disease – Public Library of Science
New CDC Guidance with 10 public health strategies to address high levels of community transmission of SARS-Cov-2, including universal use of face masks
7 Dec, 2020 | 01:10h | UTCCommentaries: Masks are critical to stopping coronavirus spread, even at home, CDC says – CNN AND CDC recommends ‘universal’ use of face masks to prevent COVID-19 spread – UPI
Commentary on Twitter
In most of the US, Covid transmission is at dangerously high levels. CDC released a new package of 10 key strategies needed to curb the spread, including universal masking and postponing travel. https://t.co/b0utHmygSI pic.twitter.com/HXjlo89WrR
— Dr. Tom Frieden (@DrTomFrieden) December 5, 2020
Spironolactone use is associated with improved outcomes in patients with heart failure with preserved ejection fraction and concomitant resistant hypertension
8 Dec, 2020 | 07:44h | UTC
Meta-analysis: Respiratory function post-infection by COVID-19. Altered diffusion capacity, restrictive pattern, and obstructive pattern were found in 39%, 15% and 7% of patients, respectively
7 Dec, 2020 | 01:04h | UTC
Commentary on Twitter
Check out our recent systematic review in post-COVID-19 patients. Altered diffusion capacity, restrictive pattern and obstructive pattern were found in 39%, 15% and 7% of patients, respectively. @VilaroJordi @lvasconcello @RestoyAlsina @BufadorBufador https://t.co/PDHcUOCEbw
— Rodrigo Torres Castro (@klgorodtorres) November 25, 2020
Myocardial injury in severe COVID-19 is similar to traditional ARDS. It is a function of baseline comorbidities, advanced age, and multisystem organ dysfunction
7 Dec, 2020 | 00:59h | UTCCommentary: Myocardial Injury in Severe COVID-19 vs. ARDS – American College of Cardiology
Commentary on Twitter
About that “permanent heart damage” people associate with #COVID19…
Study published 11/13 found odds of heart damage was found to be *lower* in intubated C19 patients than in those w/ Acute Respiratory Distress Syndrome from non-Covid causes.https://t.co/rnRGFkfl0N pic.twitter.com/NN1f3DNrC7
— AJ Kay (@AJKayWriter) November 20, 2020
The UK has approved a COVID vaccine — but scientists still have many questions. One of them is if the vaccines will prevent the transmission of the disease
7 Dec, 2020 | 00:52h | UTCThe UK has approved a COVID vaccine — here’s what scientists now want to know – Nature
Study in Germany comparing regions with vs. without mask mandates concluded that 20 d after becoming mandatory, face masks reduced new Covid-19 infections by around 45%
7 Dec, 2020 | 00:46h | UTC
Case-control study: Meningococcus B vaccine prevents disease with 79 percent effectiveness in children and young adults
6 Dec, 2020 | 23:48h | UTCCommentary: Meningococcus B vaccine prevents disease with 79 per cent effectiveness in under-18s – University of Bristol
Commentary on Twitter
In this matched case-control study, children who developed meningococcal disease were less likely to have been vaccinated with 4CMenB vs matched controls without meningococcal disease during the first 5y of vaccine availability in Portugal https://t.co/dGagZ3aTIB @adamhfinn
— JAMA (@JAMA_current) December 3, 2020
Randomized trial: High-dose influenza vaccine shows no additional benefit for heart disease patients
7 Dec, 2020 | 00:44h | UTCEditorial: Influenza Vaccine for Patients With High-risk Cardiovascular Disease
Commentary: High-dose influenza vaccine shows no additional benefit for heart disease patients – NIH News Releases
Commentary on Twitter
In patients w high-risk CVD, high-dose trivalent influenza vaccine, vs standard-dose quadrivalent vaccine, did not significantly reduce all-cause mortality or cardiopulmonary hospitalizations https://t.co/I3XygBajQL
— JAMA (@JAMA_current) December 4, 2020
Meta-analysis reinforces the safety of betablockers in patients with COPD and cardiovascular disease
6 Dec, 2020 | 23:30h | UTCCommentary: Beta-Blockers in Patients With COPD and CVD – American College of Cardiology
Meta-analysis: High-quality evidence supports fecal microbiota transplantation is effective for recurrent Clostridioides difficile infection
6 Dec, 2020 | 23:35h | UTC
Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update From the National Asthma Education and Prevention Program
4 Dec, 2020 | 08:33h | UTCEditorial: Evolving Strategies for Long-term Asthma Management – JAMA
Commentaries: New Asthma Guidelines Published in The Journal of Allergy and Clinical Immunology, an Official Journal of the AAAAI – American Academy of Allergy, Asthma & Immunology AND New updates to federal guidelines revamp asthma management – NHLBI News
New WHO Guidance on masks for the public and health workers in the context of COVID-19
4 Dec, 2020 | 08:24h | UTCMask use in the context of COVID-19 – World Health Organization
Commentaries: WHO fine-tunes advice on COVID masks for public, health workers – Reuters AND WHO updates mask advice, recommending they be worn in indoor, poorly ventilated areas – CBC
Commentary on Twitter
.@WHO has tightened its guidance on face masks, recommending that where COVID-19 is spreading, masks be worn by everyone in healthcare settings, indoor low ventilated areas & outdoors when a distance of 3 ft from others cannot be maintained. #MaskUpAmerica https://t.co/dJUJ2syDMN
— IDSA (@IDSAInfo) December 3, 2020
Meta-analysis: Epidural corticosteroid injections for sciatica are effective, although the effects are small and short-term
4 Dec, 2020 | 08:26h | UTC
Why the CDC changed its Covid-19 quarantine guidelines
4 Dec, 2020 | 08:18h | UTCWhy the CDC changed its Covid-19 quarantine guidelines – Vox
CDC Guideline: Duration of Isolation and Precautions for Adults with COVID-19 – Centers for Disease Control and Prevention
Could COVID delirium bring on dementia?
4 Dec, 2020 | 08:11h | UTCCould COVID delirium bring on dementia? – Nature
UK becomes first country to authorize Pfizer/BioNTech’s Covid-19 vaccine, first shots roll out next week
3 Dec, 2020 | 08:44h | UTCPress release: UK medicines regulator gives approval for first UK COVID-19 vaccine – Medicines and Healthcare products Regulatory Agency
See also: Covid-19: Pfizer/BioNTech vaccine judged safe for use in UK – BBC AND Expert reaction to news that the MHRA has approved the Pfizer/BioNTech COVID-19 vaccine for mass UK roll out – Science Media Centre AND UK approves Pfizer/BioNTech Covid vaccine for rollout next week – The Guardian
WHO Solidarity Trial: Remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19
3 Dec, 2020 | 08:47h | UTCAudio Interview: Caring for Hospitalized Patients with Covid-19
Commentary on Twitter (thread – click for more)
The biggest multinational pandemic randomised trial #SOLIDARITYtrial published in the New England Journal of Medicine. https://t.co/VbpbpziFwm
WHO, trial leaders, numerous countries, hospitals, doctors, nurses, patients & many others are to be congratulated!
Key results 👇🏾 1/5 pic.twitter.com/Xe9K6EfUpc
— Kari Tikkinen (@KariTikkinen) December 2, 2020
Review: Cytokine Storm
3 Dec, 2020 | 08:46h | UTCCytokine Storm – New England Journal of Medicine
Commentary on Twitter
Cytokine storm is a prominent feature in severe #COVID19. This new @NEJM review on it is as good as it gets. By @DavidFajgenbaum @carlhjune @PennMedicine https://t.co/a4qE7xGR58 pic.twitter.com/Ul1HrnL8Ve
— Eric Topol (@EricTopol) December 2, 2020
Randomized trial: In treatment naive early rheumatoid arthritis, a treatment based on methotrexate and low dose corticosteroids was safe and effective and non-inferior to certolizumab and tocilizumab, but not to abatacept
3 Dec, 2020 | 08:35h | UTC
CDC to shorten COVID-19 quarantine to 10 days, 7 with test
3 Dec, 2020 | 08:40h | UTCCDC to shorten COVID-19 quarantine to 10 days, 7 with test – Associated Press
Commentary: CDC Shortens Its COVID-19 Quarantine Recommendations – NPR
Guideline for the perioperative management of hip fractures 2020
3 Dec, 2020 | 08:30h | UTCGuideline for the management of hip fractures 2020 – Anaesthesia
Commentary on Twitter
🔐This new @Assoc_Anaes guideline for the management of hip fractures from @IainMoppett and colleagues contains more specific recommendations about controversial areas of patient management than were made in 2011.
Available now and #FOAMed forever!
🔗https://t.co/B5cdxSx2mU pic.twitter.com/8nQiUNpdS2
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) December 2, 2020
Review: Perioperative venous thromboembolism prophylaxis
3 Dec, 2020 | 08:28h | UTCPerioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings