Spironolactone use is associated with improved outcomes in patients with heart failure with preserved ejection fraction and concomitant resistant hypertension 8 Dec, 2020 | 07:44h | UTC Spironolactone Use and Improved Outcomes in Patients With Heart Failure With Preserved Ejection Fraction With Resistant Hypertension – Journal of the American Heart Association Commentary: Spironolactone use associated with improved outcomes for patients with HFpEF and resistant hypertension – 2 Minute Medicine