Internal Medicine
Perspective | Don’t Be Surprised When Vaccinated People Get Infected
24 Mar, 2021 | 08:28h | UTCDon’t Be Surprised When Vaccinated People Get Infected – The Atlantic
Opinion | Perfect as the enemy of good: tracing transmissions with low-sensitivity tests to mitigate SARS-CoV-2 outbreaks
24 Mar, 2021 | 08:22h | UTC
Commentary on Twitter
Editor's Pick—How do different contact tracing & testing methods work? What resources are needed for each? How do features of #COVID19 transmission influence their effectiveness?
Read the Personal View by @LeeKShaffer et al. in @LancetMicrobe. https://t.co/ruHV0RW6aY pic.twitter.com/19f7vCrt0I
— The Lancet (@TheLancet) March 18, 2021
Study: More than half of antibiotics prescribed in US hospitals were not consistent with recommended prescribing practices
21 Mar, 2021 | 21:44h | UTCAssessment of the Appropriateness of Antimicrobial Use in US Hospitals
Commentary: New findings spur call to reduce improper antibiotic use in hospitals – CIDRAP
Commentary on Twitter
Newly published CDC data estimates that more than half of antibiotics prescribed in U.S. hospitals for selected prescribing events were not consistent with recommended prescribing practices. https://t.co/oZXNX26UiD pic.twitter.com/hUOrRxsPJG
— CDC Emerging Infections (@CDC_NCEZID) March 18, 2021
[Press release – not published yet] AstraZeneca vaccine 79% effective for preventing symptomatic COVID-19
23 Mar, 2021 | 02:36h | UTCCommentaries: AstraZeneca vaccine is 79% effective against symptomatic Covid-19, company says – CNN AND AstraZeneca’s Covid-19 vaccine shows better-than-expected efficacy in U.S. trial – STAT AND Expert reaction to press release from AstraZeneca announcing interim data on safety and efficacy from the US trial of the Oxford-AstraZeneca COVID-19 vaccine – Science Media Centre AND AstraZeneca Publishes Reassuring Trial Data, But Vaccine Hesitancy Remains Widespread In European Union – Health Policy Watch
Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery
23 Mar, 2021 | 02:33h | UTCSARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery – Anaesthesia
Commentary on Twitter
Our research has underpinned key recommendations in new guidance on SARS-CoV-2 infection & elective surgery from @Assoc_Anaes & @RCoANews & @RCSnews.
This guideline can act as a template for policy makers in other countries!
🆓https://t.co/kKgJXFf0vd pic.twitter.com/mJRasJTJws
— COVIDSurg (@CovidSurg) March 20, 2021
EMA advises against use of ivermectin for the prevention or treatment of COVID-19 outside randomized clinical trials
23 Mar, 2021 | 02:30h | UTCRelated: FDA: Why you should not use Ivermectin to treat or prevent COVID-19 (statement, commentary, and RCT)
Opinion | We need to start thinking more critically — and speaking more cautiously — about long Covid
23 Mar, 2021 | 02:28h | UTCWe need to start thinking more critically — and speaking more cautiously — about long Covid – STAT
Review | Post-acute COVID-19 syndrome
23 Mar, 2021 | 02:26h | UTCPost-acute COVID-19 syndrome – Nature Medicine
News Release: Study underscores need for multidisciplinary care for COVID-19 long-haulers – Dana-Farber Cancer Institute
Lung ultrasound for the early diagnosis of COVID-19 pneumonia: an international multicenter study
23 Mar, 2021 | 02:20h | UTC
Commentary on Twitter
Lung #ultrasound based approach for early diagnosis of #COVID19 pneumonia:
➡️20 US/European hospitals
➡️1462 pts
Combining #LUS patterns of probability + clinical characteristics allow to rapidly rule in/out #SARSCoV2 pneumonia at bedside w high accuracy!https://t.co/GqsOZoIdgc pic.twitter.com/eENciXi9Cf— Intensive Care Medicine (@yourICM) March 20, 2021
Expert consensus statements for the management of COVID-19-related acute respiratory failure
21 Mar, 2021 | 22:05h | UTC
Commentary on Twitter
👌Expert consensus statements for the management of 👍💥 COVID-19-related acute respiratory failure using a Delphi method.
👇👇👇👇👇https://t.co/ujt8669VAb pic.twitter.com/AlT0ZkdKSc— RECAT👩🏽⚕️🏥👨🏽⚕️🇲🇽🫀 (@LeslieMegom) March 17, 2021
RCT: Pegcetacoplan vs. Eculizumab in Paroxysmal Nocturnal Hemoglobinuria
21 Mar, 2021 | 21:32h | UTC
WHO Report: Kicking off a global conversation about ageism
19 Mar, 2021 | 08:12h | UTCGlobal report on ageism – World Health Organization
News release: Kicking off a global conversation about ageism: launch of the first UN Global report on ageism – World Health Organization
Bioethics | “Europe’s Vaccine Ethics Call: Do No Harm and Let More Die?”
21 Mar, 2021 | 21:50h | UTCEurope’s Vaccine Ethics Call: Do No Harm and Let More Die? – The New York Times (free registration may be required)
Related opinion: Covid-19 vaccine adverse events: balancing monitoring with confidence in vaccines – The BMJ Opinion
See also: European Medicines Agency finds AstraZeneca vaccine is safe and benefits outweigh the risks (Statement and commentaries) AND Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) COVID-19 subcommittee on safety signals related to the AstraZeneca COVID-19 vaccine – World Health Organization AND Update on the safety of COVID-19 Vaccine AstraZeneca (statement and commentaries)
Commentary on Twitter
Many bioethicists have a problem with how Europe halted use of the AstraZeneca vaccine. Keeping the vaccine available would have allowed people “to consensually protect themselves from a big risk by taking a very small one.” https://t.co/qctELhfFGI
— NYT Health (@NYTHealth) March 20, 2021
Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19: JACC State-of-the-Art Review
21 Mar, 2021 | 21:49h | UTC
Commentary on Twitter
@JACCJournals: We share a systematic summary of #anticcogulation,#antiplatelet, and #fibrinolysis #RCTs in #COVID19. Amazing work by @AzitaTalasaz and a stellar multidisciplinary team! Figs illustrate areas where we’ll have evidence, & the gaps. Link: https://t.co/t4ksxwjAze pic.twitter.com/0Th3OZBXOY
— Behnood Bikdeli (@bbikdeli) March 16, 2021
Modeling Study: Vaccination alone is unlikely to contain COVID-19 infections in UK
21 Mar, 2021 | 21:46h | UTCCommentaries: Risking further COVID-19 waves despite vaccination – The Lancet Infectious Diseases AND Vaccination alone is unlikely to contain COVID-19 infections in UK – The Lancet
Commentary on Twitter
Vaccination alone is unlikely to contain #COVID19 infections in UK, suggests modelling study in @TheLancetInfDis—gradual release of control measures, high vaccine uptake, and high efficacy vaccine essential to minimise future waves. https://t.co/zpbPsYVHS2 pic.twitter.com/v47v6ux4r6
— The Lancet (@TheLancet) March 19, 2021
Cohort study: Fish consumption linked to reduced risk of major cardiovascular complications among patients with prior cardiovascular disease, but not in the general population
19 Mar, 2021 | 08:03h | UTCAssociations of Fish Consumption With Risk of Cardiovascular Disease and Mortality Among Individuals With or Without Vascular Disease From 58 Countries – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Study finds two servings of fish per week can help prevent recurrent heart disease – McMaster University
Author interview: Fish Consumption and Risk of Cardiovascular Disease or Mortality With or Without Vascular Disease
Fish intake of up to 175 grams (about 2 servings) weekly is associated with a lower risk of major cardiovascular events and overall mortality in high-risk individuals or patients with existing vascular disease, but not in the general population https://t.co/Jz9RTYtgSa
— JAMA Internal Medicine (@JAMAInternalMed) March 8, 2021
Podcast | Addiction Medicine Triple Distilled
19 Mar, 2021 | 08:00h | UTC#259 Addiction Medicine Triple Distilled – The Curbsiders
M-A: Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments
19 Mar, 2021 | 07:52h | UTC
RCT: Intermediate-dose enoxaparin (1 mg/kg/d) not better than standard-dose prophylactic anticoagulation in patients with Covid-19 admitted to the intensive care unit
19 Mar, 2021 | 08:42h | UTCEditorial: Finding the Optimal Thromboprophylaxis Dose in Patients With COVID-19 – JAMA
Commentary on Twitter
Intermediate-dose prophylactic enoxaparin (1 mg/kg/d) had no effect on a primary composite outcome of adjudicated venous or arterial thrombosis, ECMO, or 30-d mortality vs standard dose enoxaparin among ICU patients w #COVID19 https://t.co/L6UdB31J7V
— JAMA (@JAMA_current) March 18, 2021
European Medicines Agency finds AstraZeneca vaccine is safe and benefits outweigh the risks
19 Mar, 2021 | 08:37h | UTCCommentaries: Restoring confidence after the covid-19 Oxford/AstraZeneca vaccine pause will be an uphill battle – The BMJ Opinion AND European Medicines Agency: AstraZeneca Vaccine Safe – Benefits Outweigh Risks – Despite Possible Rare Events – Health Policy Watch AND Expert reaction to announcement from EMA on Oxford-AstraZeneca vaccine and blood clots – Science Media Centre AND European regulators say AstraZeneca vaccine safe, but can’t rule out rare events – CIDRAP AND AstraZeneca vaccine safe, but rare risk of blood clots not ruled out, EU regulator says – LiveScience AND European Medicines Agency Finds AstraZeneca Vaccine Safe And Effective – NPR
Current evidence for COVID-19 therapies: a systematic literature review
19 Mar, 2021 | 08:36h | UTC
SARS-CoV-2 transmission without symptoms
19 Mar, 2021 | 08:30h | UTCSARS-CoV-2 transmission without symptoms – Science (a few articles per month are free)
How do you treat coronavirus? Here are physicians’ best strategies
19 Mar, 2021 | 08:33h | UTCHow do you treat coronavirus? Here are physicians’ best strategies – Science (a few articles per month are free)
CDC: SARS-CoV-2 Variants of Concern
19 Mar, 2021 | 08:28h | UTCSARS-CoV-2 Variants – Centers for Disease Control and Prevention
Commentaries: Coronavirus strains first detected in California are officially ‘variants of concern,’ CDC says – CNN AND CDC IDs new COVID-19 variants of concern as hot spots reemerge – CIDRAP
Leprosy drug holds promise as at-home treatment for COVID-19
19 Mar, 2021 | 08:22h | UTCOriginal article: Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 – Nature